Genetic and Structure-Function Studies of Missense Mutations in Human Endothelial Lipase

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Razzaghi, Hamid ^a   Tempczyk Russell, Anna ^b   Haubold, Kurt ^a   Santorico, Stephanie A ^c   Shokati, Touraj ^d   Christians, Uwe ^d   Churchill, Mair E A ^d  

^a UNIVERSITY OF COLORADO   (United States)

^b ACCELRYS INC   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; ENDOTHELIAL LIPASE; FATTY ACID; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ALPHA CHAIN; ARTICLE; BETA CHAIN; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENDOTHELIAL LIPASE GENE; ETHNICITY; FEMALE; GENE ACTIVITY; GENE INTERACTION; GENE LOCATION; GENETIC ASSOCIATION; GENETIC CODE; GENETIC SCREENING; GENETIC VARIABILITY; HISPANIC; HUMAN; LIPID COMPOSITION; LIPIDOMICS; MAJOR CLINICAL STUDY; MISSENSE MUTATION; MUTATIONAL ANALYSIS; PROTEIN DOMAIN; REGULATOR GENE; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION;

ALLELES; AMINO ACID SEQUENCE; CHOLESTEROL; CHOLESTEROL, HDL; COLORADO; ENZYME ACTIVATION; GENETIC ASSOCIATION STUDIES; GENOTYPE; HEPARAN SULFATE PROTEOGLYCANS; HISPANIC AMERICANS; HYDROLYSIS; INFLAMMATION; LIPASE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PHOSPHOLIPASES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84875420466     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0055716     Document Type: Article

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