New insights into the role of HDL as an anti-inflammatory agent in the prevention of cardiovascular disease

Current Cardiology Reports

Volumn 9, Issue 6, 2007, Pages 493-498

  Barter, Philip J ^a   Puranik, Rajesh ^b   Rye, Kerry Anne ^b  

^a HEART RESEARCH INSTITUTE   (Australia)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; APOLIPOPROTEIN A1; APOLIPOPROTEIN A4; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FENOFIBRATE; HIGH DENSITY LIPOPROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MYELOPEROXIDASE; PHOSPHATIDYLCHOLINE; PHOSPHOLIPID; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; SCAVENGER RECEPTOR BI; VASCULAR CELL ADHESION MOLECULE 1;

ACUTE CORONARY SYNDROME; ANTICOAGULATION; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTERY WALL; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CEREBROVASCULAR ACCIDENT; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL TRANSPORT; CHRONIC INFLAMMATION; FOAM CELL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIPID COMPOSITION; LIPID DIET; LIPOPROTEIN BLOOD LEVEL; LOW DRUG DOSE; NONHUMAN; REVIEW; SINGLE DRUG DOSE;

ANTI-INFLAMMATORY AGENTS; APOLIPOPROTEIN A-I; CARDIOVASCULAR DISEASES; CHOLESTEROL, HDL; ENDOTHELIUM, VASCULAR; HUMANS; INFLAMMATION;

EID: 36049023700     PISSN: 15233782     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02938394     Document Type: Review

References (46)

1. Gordon T, Castelli WP, Hjortland MC, et al.: High density lipoprotein as a protective factor against coronary heart disease: the Framingham Study. Am J Med 1977, 62:707-714.
2. Miller M, Seidler A, Kwiterovich PO, Pearson TA: Long-term predictors of subsequent cardiovascular events with coronary artery disease and "desirable" levels of plasma total cholesterol. Circulation 1992, 86:1165-1170.
3. Badimon JJ, Badimon L, Fuster V: Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit. J Clin Invest 1990, 85:1234-1241.
4. Pászty C, Maeda N, Verstuyft J, Rubin EM: Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. J Clin Invest 1994, 94:899-903.
5. Plump AS, Scott CJ, Breslow JL: Human apolipoprotein A-I gene expression increases high density lipoprotein and suppresses atherosclerosis in the apolipoprotein E-deficient mouse. Proc Natl Acad Sci USA 1994, 91:9607-9611.
6. Rubin EM, Krauss RM, Spangler EA, et al.: Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI. Nature 1991, 353:265-267.
7. Duffy D, Rader DJ: Emerging therapies targeting high-density lipoprotein metabolism and reverse cholesterol transport. Circulation 2006, 113:1140-1150.
8. Durrington PN, Mackness B, Mackness MI: Paraoxonase and atherosclerosis. Arterioscler Thromb Vasc Biol 2001, 21:473-480.
9. Spieker LE, Sudano I, Hurlimann D, et al.: High-density lipoprotein restores endothelial function in hypercholesterolemic men. Circulation 2002, 105:1399-1402.
10. Bisoendial RJ, Hovingh GK, Levels JH, et al.: Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein. Circulation 2003, 107:2944-2948.
11. Suc I, Escargueil-Blanc I, Troly M, et al.: HDL and ApoA prevent cell death of endothelial cells induced by oxidized LDL. Arterioscler Thromb Vasc Biol 1997, 17: 2158-2166.
12. Sugano M, Tsuchida K, Makino N: High-density lipoproteins protect endothelial cells from tumor necrosis factor-alpha-induced apoptosis. Biochem Biophys Res Commun 2000, 272:872-876.
13. Speidel MT, Booyse FM, Abrams A, et al.: Lipolyzed hypertriglyceridemic serum and triglyceride-rich lipoprotein cause lipid accumulation in and are cytotoxic to cultured human endothelial cells: high density lipoproteins inhibit this cytotoxicity. Thromb Res 1990, 58:251-264.
14. Hui DY, Noel JG, Harmony JA: Binding of plasma low density lipoproteins to erythrocytes. Biochim Biophys Acta 1981, 664:513-526.
15. Lerch PG, Spycher MO, Doran JE: Reconstituted high density lipoprotein (rHDL) modulates platelet activity in vitro and ex vivo. Thromb Haemost 1998, 80:316-320.
16. Rosenson RS, Lowe GD: Effects of lipids and lipoproteins on thrombosis and rheology. Atherosclerosis 1998, 140:271-280.
17. Seetharam D, Mineo C, Gormley AK, et al.: High-density lipoprotein promotes endothelial cell migration and reendothelialization via scavenger receptor-B type I. Circ Res 2006, 98:63-72.
18. Tso C, Martinic G, Fan WH, et al.: High-density lipoproteins enhance progenitor-mediated endothelium repair in mice. Arterioscler Thromb Vasc Biol 2006, 26:1144-1149.
19. Cockerill GW, Rye KA, Gamble JR, et al.: High-density lipoproteins inhibit cytokine-induced expression of endothelial cell adhesion molecules. Arterioscler Thromb Vasc Biol 1995, 15:1987-1994.
20. Calabresi L, Franceschini G, Sirtori CR, et al.: Inhibition of VCAM-1 expression in endothelial cells by reconstituted high density lipoproteins. Biochem Biophys Res Commun 1997, 238:61-65.
21. Xia P, Vadas MA, Rye KA, et al.: High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway: a possible mechanism for protection against atherosclerosis by HDL. J Biol Chem 1999, 274:33143-33147.
22. Ashby DT, Rye KA, Clay MA, et al.: Factors influencing the ability of HDL to inhibit expression of vascular cell adhesion molecule-1 in endothelial cells. Arterioscler Thromb Vasc Biol 1998, 18:1450-1455.
23. Baker PW, Rye KA, Gamble JR, et al.: Ability of reconstituted high density lipoproteins to inhibit cytokine-induced expression of vascular cell adhesion molecule-1 in human umbilical vein endothelial cells. J Lipid Res 1999, 40:345-353.
24. Baker PW, Rye KA, Gamble JR, et al.: Phospholipid composition of reconstituted high density lipoproteins influences their ability to inhibit endothelial cell adhesion molecule expression. J Lipid Res 2000, 41:1261-1267.
25. Maier JA, Barenghi L, Pagani F, et al.: The protective role of high-density lipoprotein on oxidized-low-density-lipoprotein-induced U937/endothelial cell interactions. Eur J Biochem 1994, 221:35-41.
26. Moudry R, Spycher MO, Doran JE: Reconstituted high density lipoprotein modulates adherence of polymorphonuclear leukocytes to human endothelial cells. Shock 1997, 7:175-181.
27. Clay MA, Pyle DH, Rye KA, et al.: Time sequence of the inhibition of endothelial adhesion molecule expression by reconstituted high density lipoproteins. Atherosclerosis 2001, 157:23-29.
28. Park SH, Park JH, Kang JS, Kang YH: Involvement of transcription factors in plasma HDL protection against TNF-alpha-induced vascular cell adhesion molecule-1 expression. Int J Biochem Cell Biol 2003, 35:168-182.
29. Schmidt A, Geigenmüller S, Völker W, Buddecke E: The antiatherogenic and antiinflammatory effect of HDL-associated lysosphingolipids operates via Akt --> NF-kappaB signalling pathways in human vascular endothelial cells. Basic Res Cardiol 2006, 101:109-116.
30. Dimayuga P, Zhu J, Oguchi S, et al.: Reconstituted HDL containing human apolipoprotein A-1 reduces VCAM-1 expression and neointima formation following periadventitial cuff-induced carotid injury in apoE null mice. Biochem Biophys Res Commun 1999, 264:465-468.
31. Rong JX, Li J, Reis ED, et al.: Elevating high-density lipoprotein cholesterol in apolipoprotein E-deficient mice remodels advanced atherosclerotic lesions by decreasing macrophage and increasing smooth muscle cell content. Circulation 2001, 104:2447-2452.
32. Nicholls SJ, Cutri B, Worthley SG, et al.: Impact of short-term administration of high-density lipoproteins and atorvastatin on atherosclerosis in rabbits. Arterioscler Thromb Vasc Biol 2005, 25:2416-2421.
33. Paterno R, Ruocco A, Postiglione A, et al.: Reconstituted high-density lipoprotein exhibits neuroprotection in two rat models of stroke. Cerebrovasc Dis 2004, 17:204-211.
34. Cockerill GW, McDonald MC, Mota-Filipe H, et al.: High density lipoproteins reduce organ injury and organ dysfunction in a rat model of hemorrhagic shock. FASEB J 2001, 15:1941-1952.
35. Cockerill GW, Huehns TY, Weerasinghe A, et al.: Elevation of plasma high-density lipoprotein concentration reduces interleukin-1-induced expression of E-selectin in an in vivo model of acute inflammation. Circulation 2001, 103:108-112.
36. Levkau B, Hermann S, Theilmeier G, et al.: High-density lipoprotein stimulates myocardial perfusion in vivo. Circulation 2004, 110:3355-3359.
37. McDonald MC, Dhadly P, Cockerill GW, et al.: Reconstituted high-density lipoprotein attenuates organ injury and adhesion molecule expression in a rodent model of endotoxic shock. Shock 2003, 20:551-557.
38. Cuzzocrea S, Dugo L, Patel NS, et al.: High-density lipoproteins reduce the intestinal damage associated with ischemia/reperfusion and colitis. Shock 2004, 21:342-351.
39. Vowinkel T, Mori M, Krieglstein CF, et al.: Apolipoprotein A-IV inhibits experimental colitis. J Clin Invest 2004, 114:260-269.
40. Nicholls SJ, Dusting GJ, Cutri B, et al.: Reconstituted high-density lipoproteins inhibit the acute pro-oxidant and proinflammatory vascular changes induced by a periarterial collar in normocholesterolemic rabbits. Circulation 2005, 111:1543-1550.
41. Puranik R, Bao S, Nobecourt E, et al.: Low dose apolipoprotein A-I rescues carotid arteries from inflammation in vivo. Atherosclerosis 2007 [Epub ahead of print].
42. Calabresi L, Gomaraschi M, Villa B, et al.: Elevated soluble cellular adhesion molecules in subjects with low HDL-cholesterol. Arterioscler Thromb Vasc Biol 2002, 22:656-661.
43. Nicholls SJ, Lundman P, Harmer JA, et al.: Consumption of saturated fat impairs the anti-inflammatory properties of high-density lipoproteins and endothelial function. J Am Coll Cardiol 2006, 48:715-720.
44. Navab M, Imes SS, Hama SY, et al.: Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein. J Clin Invest 1991, 88:2039-2046.
45. Nissen SE, Tsunoda T, Tuzcu EM, et al.: Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial. JAMA 2003, 290:2292-2300.
46. Kee P, Rye KA, Taylor JL, et al.: Metabolism of apoA-I as lipid-free protein or as component of discoidal and spherical reconstituted HDLs: studies in wild-type and hepatic lipase transgenic rabbits. Arterioscler Thromb Vasc Biol 2002, 22:1912-1917.