Structure-function analysis of D9N and N291S mutations in human lipoprotein lipase using molecular modelling

Journal of Molecular Graphics and Modelling

Volumn 19, Issue 6, 2001, Pages

  Razzaghi, Hamid ^a   Day, Billy W ^a   McClure, Richard J ^b   Kamboh, M Ilyas ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Lipid metabolism; Lipoprotein lipase; LPL; Molecular modelling; Mutation; Structure function

Indexed keywords

CHOLESTEROL; DIMERIZATION; GENES; HYDROPHOBICITY; LIPIDS; METABOLISM; PROTEINS;

MUTATIONS;

MOLECULAR GRAPHICS;

APOLIPOPROTEIN C2; LIPOPROTEIN LIPASE; MUTANT PROTEIN; TRIACYLGLYCEROL LIPASE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; ATOM; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME STRUCTURE; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR MODEL; MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; THREE DIMENSIONAL IMAGING;

EID: 0034846137     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1093-3263(00)00096-6     Document Type: Article

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