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Volumn 18, Issue 4, 2013, Pages 451-460

GSK-3β overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons in vivo

Author keywords

adult hippocampal neurogenesis; Alzheimer's disease; environmental enrichment; GSK 3; post synaptic density; PSD95; retrovirus

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA;

EID: 84875416121     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2013.4     Document Type: Article
Times cited : (106)

References (50)
  • 1
    • 65549133778 scopus 로고    scopus 로고
    • Adult-generated hippocampal neurons allow the flexible use of spatially precise learning strategies
    • Garthe A, Behr J, Kempermann G. Adult-generated hippocampal neurons allow the flexible use of spatially precise learning strategies. PLoS ONE 2009; 4: e5464.
    • (2009) PLoS ONE , vol.4
    • Garthe, A.1    Behr, J.2    Kempermann, G.3
  • 2
    • 33645097490 scopus 로고    scopus 로고
    • A functional hypothesis for adult hippocampal neurogenesis: Avoidance of catastrophic interference in the dentate gyrus
    • Wiskott L, Rasch MJ, Kempermann G. A functional hypothesis for adult hippocampal neurogenesis: avoidance of catastrophic interference in the dentate gyrus. Hippocampus 2006; 16: 329-343.
    • (2006) Hippocampus , vol.16 , pp. 329-343
    • Wiskott, L.1    Rasch, M.J.2    Kempermann, G.3
  • 3
    • 0033360314 scopus 로고    scopus 로고
    • Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus
    • van Praag H, Kempermann G, Gage FH. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci 1999; 2: 266-270.
    • (1999) Nat Neurosci , vol.2 , pp. 266-270
    • Van Praag, H.1    Kempermann, G.2    Gage, F.H.3
  • 4
    • 0030597165 scopus 로고    scopus 로고
    • Immunocytochemistry of tau phosphoserine 413 and tau protein kinase i in Alzheimer pathology
    • Shiurba RA, Ishiguro K, Takahashi M, Sato K, Spooner ET, Mercken M et al. Immunocytochemistry of tau phosphoserine 413 and tau protein kinase I in Alzheimer pathology. Brain Res 1996; 737: 119-132.
    • (1996) Brain Res , vol.737 , pp. 119-132
    • Shiurba, R.A.1    Ishiguro, K.2    Takahashi, M.3    Sato, K.4    Spooner, E.T.5    Mercken, M.6
  • 5
    • 0036942638 scopus 로고    scopus 로고
    • The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease
    • Leroy K, Boutajangout A, Authelet M, Woodgett JR, Anderton BH, Brion JP. The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease. Acta Neuropathol 2002; 103: 91-99.
    • (2002) Acta Neuropathol , vol.103 , pp. 91-99
    • Leroy, K.1    Boutajangout, A.2    Authelet, M.3    Woodgett, J.R.4    Anderton, B.H.5    Brion, J.P.6
  • 6
    • 0442276554 scopus 로고    scopus 로고
    • The glamour and gloom of glycogen synthase kinase-3
    • Jope RS, Johnson GV. The glamour and gloom of glycogen synthase kinase-3. Trends Biochem Sci 2004; 29: 95-102.
    • (2004) Trends Biochem Sci , vol.29 , pp. 95-102
    • Jope, R.S.1    Johnson, G.V.2
  • 7
    • 79959223383 scopus 로고    scopus 로고
    • GSK3 function in the brain during development, neuronal plasticity, and neurodegeneration
    • Salcedo-Tello P, Ortiz-Matamoros A, Arias C. GSK3 function in the brain during development, neuronal plasticity, and neurodegeneration. Int J Alzheimer's Dis 2011; 2011: 189728.
    • (2011) Int J Alzheimer's Dis , pp. 189728
    • Salcedo-Tello, P.1    Ortiz-Matamoros, A.2    Arias, C.3
  • 8
    • 79959223383 scopus 로고    scopus 로고
    • GSK3 function in the brain during development, neuronal plasticity, and neurodegeneration
    • Salcedo-Tello P, Ortiz-Matamoros A, Arias C. GSK3 function in the brain during development, neuronal plasticity, and neurodegeneration. Int J Alzheimers Dis 2011; 2011: 189728.
    • (2011) Int J Alzheimers Dis , pp. 189728
    • Salcedo-Tello, P.1    Ortiz-Matamoros, A.2    Arias, C.3
  • 9
    • 33847113902 scopus 로고    scopus 로고
    • LTP inhibits LTD in the hippocampus via regulation of GSK3beta
    • Peineau S, Taghibiglou C, Bradley C, Wong TP, Liu L, Lu J et al. LTP inhibits LTD in the hippocampus via regulation of GSK3beta. Neuron 2007; 53: 703-717.
    • (2007) Neuron , vol.53 , pp. 703-717
    • Peineau, S.1    Taghibiglou, C.2    Bradley, C.3    Wong, T.P.4    Liu, L.5    Lu, J.6
  • 11
    • 49849085127 scopus 로고    scopus 로고
    • Non-cell-Autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation
    • Choi SH, Veeraraghavalu K, Lazarov O, Marler S, Ransohoff RM, Ramirez JM et al. Non-cell-Autonomous effects of presenilin 1 variants on enrichment-mediated hippocampal progenitor cell proliferation and differentiation. Neuron 2008; 59: 568-580.
    • (2008) Neuron , vol.59 , pp. 568-580
    • Choi, S.H.1    Veeraraghavalu, K.2    Lazarov, O.3    Marler, S.4    Ransohoff, R.M.5    Ramirez, J.M.6
  • 12
  • 13
    • 34548246475 scopus 로고    scopus 로고
    • The dentate gyrus in Alzheimer's disease
    • Ohm TG. The dentate gyrus in Alzheimer's disease. Prog Brain Res 2007; 163: 723-740.
    • (2007) Prog Brain Res , vol.163 , pp. 723-740
    • Ohm, T.G.1
  • 14
    • 0003921607 scopus 로고    scopus 로고
    • Paxinos G (ed.) The Human Nervous system Elsevier Academic Press: San Diego, USA
    • Paxinos G. The human nervous system. In: Paxinos G (ed.). The Human Nervous system. Elsevier Academic Press: San Diego, USA, 2004, pp 871-914.
    • (2004) The Human Nervous System , pp. 871-914
    • Paxinos, G.1
  • 15
    • 0035863188 scopus 로고    scopus 로고
    • Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK- 3beta conditional transgenic mice
    • Lucas JJ, Hernandez F, Gomez-Ramos P, Moran MA, Hen R, Avila J. Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK- 3beta conditional transgenic mice. EMBO J 2001; 20: 27-39.
    • (2001) EMBO J , vol.20 , pp. 27-39
    • Lucas, J.J.1    Hernandez, F.2    Gomez-Ramos, P.3    Moran, M.A.4    Hen, R.5    Avila, J.6
  • 16
    • 30644474606 scopus 로고    scopus 로고
    • Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus
    • Zhao C, Teng EM, Summers Jr. RG, Ming GL, Gage FH. Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus. J Neurosci 2006; 26: 3-11.
    • (2006) J Neurosci , vol.26 , pp. 3-11
    • Zhao, C.1    Teng, E.M.2    Summers Jr., R.G.3    Ming, G.L.4    Gage, F.H.5
  • 17
    • 55949118569 scopus 로고    scopus 로고
    • Sequential development of synapses in dendritic domains during adult neurogenesis
    • Kelsch W, Lin CW, Lois C. Sequential development of synapses in dendritic domains during adult neurogenesis. Proc Natl Acad Sci USA 2008; 105(43): 16803-16808.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.43 , pp. 16803-16808
    • Kelsch, W.1    Lin, C.W.2    Lois, C.3
  • 18
    • 77957872719 scopus 로고    scopus 로고
    • Differential regulation of the variations induced by environmental richness in adult neurogenesis as a function of time: A dual birthdating analysis
    • Llorens-Martin M, Tejeda GS, Trejo JL. Differential regulation of the variations induced by environmental richness in adult neurogenesis as a function of time: a dual birthdating analysis. PLoS ONE 2010; 5: e12188.
    • (2010) PLoS ONE , vol.5
    • Llorens-Martin, M.1    Tejeda, G.S.2    Trejo, J.L.3
  • 19
    • 0007807185 scopus 로고
    • The organization of the visual cortex in the cat
    • Sholl DA. The organization of the visual cortex in the cat. J Anat 1955; 89: 33-46.
    • (1955) J Anat , vol.89 , pp. 33-46
    • Sholl, D.A.1
  • 20
    • 77957339217 scopus 로고    scopus 로고
    • Alzheimer Center Reina Sofia Foundation: Fighting the disease and providing overall solutions
    • Martinez-Martin P, Avila J. Alzheimer Center Reina Sofia Foundation: fighting the disease and providing overall solutions. J Alzheimers Dis 2010; 21: 337-348.
    • (2010) J Alzheimers Dis , vol.21 , pp. 337-348
    • Martinez-Martin, P.1    Avila, J.2
  • 21
    • 48349108322 scopus 로고    scopus 로고
    • International Society for Biological and Environmental Repositories Biopreservation and Biobanking 2012 Collection, storage, retrieval, and distribution of biological materials for research
    • doi:10.1089/ cpt 2008 9997
    • International Society for Biological and Environmental Repositories Biopreservation and Biobanking 2012. Collection, storage, retrieval, and distribution of biological materials for research. Cell Preserv Technol 2008; 6, doi:10.1089/ cpt.2008.9997.
    • (2008) Cell Preserv Technol , vol.6
  • 22
    • 80455129781 scopus 로고    scopus 로고
    • Different susceptibility to neurodegeneration of dorsal and ventral hippocampal dentate gyrus: A study with transgenic mice overexpressing GSK3beta
    • Fuster-Matanzo A, Llorens-Martin M, de Barreda EG, Avila J, Hernandez F. Different susceptibility to neurodegeneration of dorsal and ventral hippocampal dentate gyrus: a study with transgenic mice overexpressing GSK3beta. PLoS ONE 2011; 6: e27262.
    • (2011) PLoS ONE , vol.6
    • Fuster-Matanzo, A.1    Llorens-Martin, M.2    De Barreda, E.G.3    Avila, J.4    Hernandez, F.5
  • 23
    • 0032080116 scopus 로고    scopus 로고
    • Experience-induced neurogenesis in the senescent dentate gyrus
    • Kempermann G, Kuhn HG, Gage FH. Experience-induced neurogenesis in the senescent dentate gyrus. J Neurosci 1998; 18: 3206-3212.
    • (1998) J Neurosci , vol.18 , pp. 3206-3212
    • Kempermann, G.1    Kuhn, H.G.2    Gage, F.H.3
  • 24
    • 0019417721 scopus 로고
    • Structure of the granular layer of the rat dentate gyrus. A light microscopic and Golgi study
    • Seress L, Pokorny J. Structure of the granular layer of the rat dentate gyrus. A light microscopic and Golgi study. J Anat 1981; 133(Pt 2): 181-195.
    • (1981) J Anat , vol.133 , Issue.PART 2 , pp. 181-195
    • Seress, L.1    Pokorny, J.2
  • 25
    • 33646504833 scopus 로고    scopus 로고
    • A model of posttraumatic epilepsy induced by lateral fluid-percussion brain injury in rats
    • Kharatishvili I, Nissinen JP, McIntosh TK, Pitkanen A. A model of posttraumatic epilepsy induced by lateral fluid-percussion brain injury in rats. Neuroscience 2006; 140: 685-697.
    • (2006) Neuroscience , vol.140 , pp. 685-697
    • Kharatishvili, I.1    Nissinen, J.P.2    McIntosh, T.K.3    Pitkanen, A.4
  • 26
    • 0021145680 scopus 로고
    • Alzheimer's disease: Cellspecific pathology isolates the hippocampal formation
    • Hyman BT, Van Hoesen GW, Damasio AR, Barnes CL. Alzheimer's disease: cellspecific pathology isolates the hippocampal formation. Science (New York, NY) 1984; 225: 1168-1170.
    • (1984) Science (New York, NY) , vol.225 , pp. 1168-1170
    • Hyman, B.T.1    Van Hoesen, G.W.2    Damasio, A.R.3    Barnes, C.L.4
  • 27
    • 0023125687 scopus 로고
    • Morphometric and dendritic analysis of fascia dentata granule cells in human aging and senile dementia
    • de Ruiter JP, Uylings HB. Morphometric and dendritic analysis of fascia dentata granule cells in human aging and senile dementia. Brain Res 1987; 402: 217-229.
    • (1987) Brain Res , vol.402 , pp. 217-229
    • De Ruiter, J.P.1    Uylings, H.B.2
  • 28
    • 9944252377 scopus 로고    scopus 로고
    • Receptor trafficking and synaptic plasticity
    • Collingridge GL, Isaac JT, Wang YT. Receptor trafficking and synaptic plasticity. Nat Rev 2004; 5: 952-962.
    • (2004) Nat Rev , vol.5 , pp. 952-962
    • Collingridge, G.L.1    Isaac, J.T.2    Wang, Y.T.3
  • 30
    • 0348108123 scopus 로고    scopus 로고
    • Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: The 'Dr jekyll and mr hyde concept' of alzheimer's disease or the yin and yang of neuroplasticity
    • Arendt T. Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the 'Dr Jekyll and Mr Hyde concept' of Alzheimer's disease or the yin and yang of neuroplasticity. Prog Neurobiol 2003; 71: 83-248.
    • (2003) Prog Neurobiol , vol.71 , pp. 83-248
    • Arendt, T.1
  • 31
    • 33646922314 scopus 로고    scopus 로고
    • Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3
    • Engel T, Hernandez F, Avila J, Lucas JJ. Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3. J Neurosci 2006; 26: 5083-5090.
    • (2006) J Neurosci , vol.26 , pp. 5083-5090
    • Engel, T.1    Hernandez, F.2    Avila, J.3    Lucas, J.J.4
  • 32
    • 1642363745 scopus 로고    scopus 로고
    • Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments
    • Hernandez F, Borrell J, Guaza C, Avila J, Lucas JJ. Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments. J Neurochem 2002; 83: 1529-1533.
    • (2002) J Neurochem , vol.83 , pp. 1529-1533
    • Hernandez, F.1    Borrell, J.2    Guaza, C.3    Avila, J.4    Lucas, J.J.5
  • 33
    • 0029793008 scopus 로고    scopus 로고
    • Quantitative assessment of synaptic density in the outer molecular layer of the Hippocampal dentate gyrus in alzheimer's disease
    • Scheff SW, Sparks DL, Price DA. Quantitative assessment of synaptic density in the outer molecular layer of the hippocampal dentate gyrus in Alzheimer's disease. Dementia: Basel, Switzerland, 1996; 7(4): 226-232.
    • (1996) Dementia: Basel Switzerland , vol.7 , Issue.4 , pp. 226-232
    • Scheff, S.W.1    Sparks, D.L.2    Price, D.A.3
  • 34
    • 0023156372 scopus 로고
    • Dendritic extent in human dentate gyrus granule cells in normal aging and senile dementia
    • Flood DG, Buell SJ, Horwitz GJ, Coleman PD. Dendritic extent in human dentate gyrus granule cells in normal aging and senile dementia. Brain Res 1987; 402: 205-216.
    • (1987) Brain Res , vol.402 , pp. 205-216
    • Flood, D.G.1    Buell, S.J.2    Horwitz, G.J.3    Coleman, P.D.4
  • 35
    • 64949175022 scopus 로고    scopus 로고
    • Alpha- CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders
    • Yamasaki N, Maekawa M, Kobayashi K, Kajii Y, Maeda J, Soma M et al. Alpha- CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders. Mol Brain 2008; 1: 6.
    • (2008) Mol Brain , vol.1 , pp. 6
    • Yamasaki, N.1    Maekawa, M.2    Kobayashi, K.3    Kajii, Y.4    Maeda, J.5    Soma, M.6
  • 36
    • 72349096338 scopus 로고    scopus 로고
    • Microglia-Associated granule cell death in the normal adult dentate gyrus
    • Ribak CE, Shapiro LA, Perez ZD, Spigelman I. Microglia-Associated granule cell death in the normal adult dentate gyrus. Brain Struct Funct 2009; 214: 25-35.
    • (2009) Brain Struct Funct , vol.214 , pp. 25-35
    • Ribak, C.E.1    Shapiro, L.A.2    Perez, Z.D.3    Spigelman, I.4
  • 37
    • 0345189366 scopus 로고    scopus 로고
    • Inflammatory blockade restores adult hippocampal neurogenesis
    • Monje ML, Toda H, Palmer TD. Inflammatory blockade restores adult hippocampal neurogenesis. Science (New York, NY) 2003; 302: 1760-1765.
    • (2003) Science (New York, NY) , vol.302 , pp. 1760-1765
    • Monje, M.L.1    Toda, H.2    Palmer, T.D.3
  • 38
    • 81355149680 scopus 로고    scopus 로고
    • Chronic neuroinflammation impacts the recruitment of adult-born neurons into behaviorally relevant hippocampal networks
    • Belarbi K, Arellano C, Ferguson R, Jopson T, Rosi S. Chronic neuroinflammation impacts the recruitment of adult-born neurons into behaviorally relevant hippocampal networks. Brain Behav Immun 2012; 26: 18-23.
    • (2012) Brain Behav Immun , vol.26 , pp. 18-23
    • Belarbi, K.1    Arellano, C.2    Ferguson, R.3    Jopson, T.4    Rosi, S.5
  • 39
    • 0348141712 scopus 로고    scopus 로고
    • Chemokines promote quiescence and survival of human neural progenitor cells
    • Krathwohl MD, Kaiser JL. Chemokines promote quiescence and survival of human neural progenitor cells. Stem Cells (Dayton, Ohio) 2004; 22: 109-118.
    • (2004) Stem Cells (Dayton, Ohio) , vol.22 , pp. 109-118
    • Krathwohl, M.D.1    Kaiser, J.L.2
  • 40
    • 38649092266 scopus 로고    scopus 로고
    • IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress
    • Koo JW, Duman RS. IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress. Proc Natl Acad Sci USA 2008; 105(2): 751-756.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.2 , pp. 751-756
    • Koo, J.W.1    Duman, R.S.2
  • 41
    • 33746255997 scopus 로고    scopus 로고
    • Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation
    • Barkho BZ, Song H, Aimone JB, Smrt RD, Kuwabara T, Nakashima K et al. Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation. Stem Cells Dev 2006; 15: 407-421.
    • (2006) Stem Cells Dev , vol.15 , pp. 407-421
    • Barkho, B.Z.1    Song, H.2    Aimone, J.B.3    Smrt, R.D.4    Kuwabara, T.5    Nakashima, K.6
  • 42
    • 17044401322 scopus 로고    scopus 로고
    • Changes in hippocampal IL-15, related cytokines, and neurogenesis in IL-2 deficient mice
    • Beck Jr RD, Wasserfall C, Ha GK, Cushman JD, Huang Z, Atkinson MA et al. Changes in hippocampal IL-15, related cytokines, and neurogenesis in IL-2 deficient mice. Brain Res 2005; 1041: 223-230.
    • (2005) Brain Res , vol.1041 , pp. 223-230
    • Beck Jr., R.D.1    Wasserfall, C.2    Ha, G.K.3    Cushman, J.D.4    Huang, Z.5    Atkinson, M.A.6
  • 43
    • 79960208166 scopus 로고    scopus 로고
    • Enriched environment and physical activity reduce microglia and influence the fate of NG2 cells in the amygdala of adult mice
    • Ehninger D, Wang LP, Klempin F, Romer B, Kettenmann H, Kempermann G. Enriched environment and physical activity reduce microglia and influence the fate of NG2 cells in the amygdala of adult mice. Cell Tissue Res 2011; 345: 69-86.
    • (2011) Cell Tissue Res , vol.345 , pp. 69-86
    • Ehninger, D.1    Wang, L.P.2    Klempin, F.3    Romer, B.4    Kettenmann, H.5    Kempermann, G.6
  • 45
    • 0026589752 scopus 로고
    • Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment
    • Falkenberg T, Mohammed AK, Henriksson B, Persson H, Winblad B, Lindefors N. Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment. Neurosci Lett 1992; 138: 153-156.
    • (1992) Neurosci Lett , vol.138 , pp. 153-156
    • Falkenberg, T.1    Mohammed, A.K.2    Henriksson, B.3    Persson, H.4    Winblad, B.5    Lindefors, N.6
  • 46
    • 33847163934 scopus 로고    scopus 로고
    • Preferential incorporation of adultgenerated granule cells into spatial memory networks in the dentate gyrus
    • Kee N, Teixeira CM, Wang AH, Frankland PW. Preferential incorporation of adultgenerated granule cells into spatial memory networks in the dentate gyrus. Nat Neurosci 2007; 10: 355-362.
    • (2007) Nat Neurosci , vol.10 , pp. 355-362
    • Kee, N.1    Teixeira, C.M.2    Wang, A.H.3    Frankland, P.W.4
  • 47
    • 0035073115 scopus 로고    scopus 로고
    • Mechanism for increased hippocampal synaptic strength following differential experience
    • Foster TC, Dumas TC. Mechanism for increased hippocampal synaptic strength following differential experience. J Neurophysiol 2001; 85: 1377-1383.
    • (2001) J Neurophysiol , vol.85 , pp. 1377-1383
    • Foster, T.C.1    Dumas, T.C.2
  • 48
    • 63349100105 scopus 로고    scopus 로고
    • Enrich the environment to empower the brain
    • Sale A, Berardi N, Maffei L. Enrich the environment to empower the brain. Trends Neurosci 2009; 32: 233-239.
    • (2009) Trends Neurosci , vol.32 , pp. 233-239
    • Sale, A.1    Berardi, N.2    Maffei, L.3
  • 49
    • 37249012296 scopus 로고    scopus 로고
    • GluR1 links structural and functional plasticity at excitatory synapses
    • Kopec CD, Real E, Kessels HW, Malinow R. GluR1 links structural and functional plasticity at excitatory synapses. J Neurosci 2007; 27: 13706-13718.
    • (2007) J Neurosci , vol.27 , pp. 13706-13718
    • Kopec, C.D.1    Real, E.2    Kessels, H.W.3    Malinow, R.4
  • 50


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