메뉴 건너뛰기




Volumn 73, Issue 6, 2013, Pages 1969-1980

Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE; PROTEIN KINASE LYN; SMALL INTERFERING RNA; SUGEN KINASE 269; UNCLASSIFIED DRUG;

EID: 84875414367     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-1472     Document Type: Article
Times cited : (70)

References (34)
  • 2
    • 78549278133 scopus 로고    scopus 로고
    • Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells
    • Hochgrafe F, Zhang L, O'Toole SA, Browne BC, Pinese M, Porta Cubas A, et al. Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells. Cancer Res 2010; 70:9391-401.
    • (2010) Cancer Res , vol.70 , pp. 9391-9401
    • Hochgrafe, F.1    Zhang, L.2    O'Toole, S.A.3    Browne, B.C.4    Pinese, M.5    Porta Cubas, A.6
  • 3
    • 77954643220 scopus 로고    scopus 로고
    • Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected]
    • Wang Y, Kelber JA, Tran Cao HS, Cantin GT, Lin R, Wang W, et al. Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected]. Proc Natl Acad Sci U S A 2010;107:10920-5.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 10920-10925
    • Wang, Y.1    Kelber, J.A.2    Tran Cao, H.S.3    Cantin, G.T.4    Lin, R.5    Wang, W.6
  • 6
    • 65549140324 scopus 로고    scopus 로고
    • Quantitative phosphoproteomics reveals a cluster of tyrosine kinases thatmediatesSRCinvasive activity in advanced colon carcinoma cells
    • Leroy C, Fialin C, Sirvent A, Simon V, Urbach S, Poncet J, et al. Quantitative phosphoproteomics reveals a cluster of tyrosine kinases thatmediatesSRCinvasive activity in advanced colon carcinoma cells. Cancer Res 2009;69:2279-86.
    • (2009) Cancer Res , vol.69 , pp. 2279-2286
    • Leroy, C.1    Fialin, C.2    Sirvent, A.3    Simon, V.4    Urbach, S.5    Poncet, J.6
  • 9
    • 76649110554 scopus 로고    scopus 로고
    • In-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling
    • Boersema PJ, Foong LY, Ding VM, Lemeer S, van Breukelen B, Philp R, et al. In-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling. Mol Cell Proteomics 2010;9:84-99.
    • (2010) Mol Cell Proteomics , vol.9 , pp. 84-99
    • Boersema, P.J.1    Foong, L.Y.2    Ding, V.M.3    Lemeer, S.4    Van Breukelen, B.5    Philp, R.6
  • 10
    • 58149382072 scopus 로고    scopus 로고
    • Screening for EphB signaling effectors using SILAC with a linear ion trap-orbitrap mass spectrometer
    • Zhang G, Fenyo D, Neubert TA. Screening for EphB signaling effectors using SILAC with a linear ion trap-orbitrap mass spectrometer. J Proteome Res 2008;7:4715-26.
    • (2008) J Proteome Res , vol.7 , pp. 4715-4726
    • Zhang, G.1    Fenyo, D.2    Neubert, T.A.3
  • 12
    • 84861162319 scopus 로고    scopus 로고
    • KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer
    • Kelber JA, Reno T, Kaushal S, Metildi C, Wright T, Stoletov K, et al. KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer. Cancer Res 2012;72:2554-64.
    • (2012) Cancer Res , vol.72 , pp. 2554-2564
    • Kelber, J.A.1    Reno, T.2    Kaushal, S.3    Metildi, C.4    Wright, T.5    Stoletov, K.6
  • 13
    • 77957832068 scopus 로고    scopus 로고
    • Cortactinmodulates RhoA activation and expression of Cip/Kip cyclindependent kinase inhibitors to promote cell cycle progression in 11q13-amplified head and neck squamous cell carcinoma cells
    • Croucher DR, Rickwood D, Tactacan CM, Musgrove EA, Daly RJ. Cortactinmodulates RhoA activation and expression of Cip/Kip cyclindependent kinase inhibitors to promote cell cycle progression in 11q13-amplified head and neck squamous cell carcinoma cells. Mol Cell Biol 2010;30:5057-70.
    • (2010) Mol Cell Biol , vol.30 , pp. 5057-5070
    • Croucher, D.R.1    Rickwood, D.2    Tactacan, C.M.3    Musgrove, E.A.4    Daly, R.J.5
  • 14
    • 33644850529 scopus 로고    scopus 로고
    • Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein
    • Brummer T, Schramek D, Hayes VM, Bennett HL, Caldon CE, Musgrove EA, et al. Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein. J Biol Chem 2006;281:626-37.
    • (2006) J Biol Chem , vol.281 , pp. 626-637
    • Brummer, T.1    Schramek, D.2    Hayes, V.M.3    Bennett, H.L.4    Caldon, C.E.5    Musgrove, E.A.6
  • 15
    • 0033903187 scopus 로고    scopus 로고
    • Expression of c-erbB receptors, heregulin and oestrogen receptor in human breast cell lines
    • deFazio A, Chiew YE, Sini RL, Janes PW, Sutherland RL. Expression of c-erbB receptors, heregulin and oestrogen receptor in human breast cell lines. Int J Cancer 2000;87:487-98.
    • (2000) Int J Cancer , vol.87 , pp. 487-498
    • De Fazio, A.1    Chiew, Y.E.2    Sini, R.L.3    Janes, P.W.4    Sutherland, R.L.5
  • 16
    • 78651109297 scopus 로고    scopus 로고
    • Gab2 regulates cytoskeletal organization and migration of mammary epithelial cells by modulating RhoA activation
    • Herrera Abreu MT, Hughes WE, Mele K, Lyons RJ, Rickwood D, Browne BC, et al. Gab2 regulates cytoskeletal organization and migration of mammary epithelial cells by modulating RhoA activation. Mol Biol Cell 2011;22:105-16.
    • (2011) Mol Biol Cell , vol.22 , pp. 105-116
    • Herrera Abreu, M.T.1    Hughes, W.E.2    Mele, K.3    Lyons, R.J.4    Rickwood, D.5    Browne, B.C.6
  • 17
    • 0036583926 scopus 로고    scopus 로고
    • Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics
    • Ong SE, Blagoev B, Kratchmarova I, Kristensen DB, Steen H, Pandey A, et al. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics 2002;1:376-86.
    • (2002) Mol Cell Proteomics , vol.1 , pp. 376-386
    • Ong, S.E.1    Blagoev, B.2    Kratchmarova, I.3    Kristensen, D.B.4    Steen, H.5    Pandey, A.6
  • 18
    • 21144458164 scopus 로고    scopus 로고
    • Immunoaffinity profiling of tyrosine phosphorylation in cancer cells
    • Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, et al. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Nat Biotechnol 2005;23:94-101.
    • (2005) Nat Biotechnol , vol.23 , pp. 94-101
    • Rush, J.1    Moritz, A.2    Lee, K.A.3    Guo, A.4    Goss, V.L.5    Spek, E.J.6
  • 19
    • 63049110388 scopus 로고    scopus 로고
    • Comparative proteomic phenotyping of cell lines and primary cells to assess preservation of cell type-specific functions
    • Pan C, Kumar C, Bohl S, Klingmueller U, Mann M. Comparative proteomic phenotyping of cell lines and primary cells to assess preservation of cell type-specific functions. Mol Cell Proteomics 2009;8:443-50.
    • (2009) Mol Cell Proteomics , vol.8 , pp. 443-450
    • Pan, C.1    Kumar, C.2    Bohl, S.3    Klingmueller, U.4    Mann, M.5
  • 20
    • 0026729382 scopus 로고
    • The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling
    • Lowenstein EJ, Daly RJ, Batzer AG, Li W, Margolis B, Lammers R, et al. The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling. Cell 1992;70:431-42.
    • (1992) Cell , vol.70 , pp. 431-442
    • Lowenstein, E.J.1    Daly, R.J.2    Batzer, A.G.3    Li, W.4    Margolis, B.5    Lammers, R.6
  • 21
    • 0030929332 scopus 로고    scopus 로고
    • Structural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7
    • Janes PW, Lackmann M, Church WB, Sanderson GM, Sutherland RL, Daly RJ. Structural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7. J Biol Chem 1997;272:8490-7.
    • (1997) J Biol Chem , vol.272 , pp. 8490-8497
    • Janes, P.W.1    Lackmann, M.2    Church, W.B.3    Sanderson, G.M.4    Sutherland, R.L.5    Daly, R.J.6
  • 22
    • 36749093009 scopus 로고    scopus 로고
    • A structural basis for differential cell signalling by PAI-1 and PAI-2 in breast cancer cells
    • Croucher DR, Saunders DN, Stillfried GE, Ranson M. A structural basis for differential cell signalling by PAI-1 and PAI-2 in breast cancer cells. Biochem J 2007;408:203-10.
    • (2007) Biochem J , vol.408 , pp. 203-210
    • Croucher, D.R.1    Saunders, D.N.2    Stillfried, G.E.3    Ranson, M.4
  • 23
    • 33645243620 scopus 로고    scopus 로고
    • Involvement of Golgi-associated Lyn tyrosine kinase in the translocation of annexin II to the endoplasmic reticulum under oxidative stress
    • Matsuda D, Nakayama Y, Horimoto S, Kuga T, Ikeda K, Kasahara K, et al. Involvement of Golgi-associated Lyn tyrosine kinase in the translocation of annexin II to the endoplasmic reticulum under oxidative stress. Exp Cell Res 2006;312:1205-17.
    • (2006) Exp Cell Res , vol.312 , pp. 1205-1217
    • Matsuda, D.1    Nakayama, Y.2    Horimoto, S.3    Kuga, T.4    Ikeda, K.5    Kasahara, K.6
  • 24
    • 37249030356 scopus 로고    scopus 로고
    • A switch from Ecadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer
    • Gravdal K, Halvorsen OJ, Haukaas SA, Akslen LA. A switch from Ecadherin to N-cadherin expression indicates epithelial to mesenchymal transition and is of strong and independent importance for the progress of prostate cancer. Clin Cancer Res 2007;13:7003-11.
    • (2007) Clin Cancer Res , vol.13 , pp. 7003-7011
    • Gravdal, K.1    Halvorsen, O.J.2    Haukaas, S.A.3    Akslen, L.A.4
  • 25
    • 34249289041 scopus 로고    scopus 로고
    • Snail Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
    • Peinado H, Olmeda D, Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 2007;7:415-28.
    • (2007) Nat Rev Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 26
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath J, Muthuswamy SK, Brugge JS. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 2003;30:256-68.
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 28
    • 33750606752 scopus 로고    scopus 로고
    • The duplicitous nature of the Lyn tyrosine kinase in growth factor signaling
    • Hibbs ML, Harder KW. The duplicitous nature of the Lyn tyrosine kinase in growth factor signaling. Growth Factors 2006;24:137-49.
    • (2006) Growth Factors , vol.24 , pp. 137-149
    • Hibbs, M.L.1    Harder, K.W.2
  • 29
    • 61849152775 scopus 로고    scopus 로고
    • Multiple roles of Lyn kinase in myeloid cell signaling and function
    • Scapini P, Pereira S, Zhang H, Lowell CA. Multiple roles of Lyn kinase in myeloid cell signaling and function. Immunol Rev 2009;228:23-40.
    • (2009) Immunol Rev , vol.228 , pp. 23-40
    • Scapini, P.1    Pereira, S.2    Zhang, H.3    Lowell, C.A.4
  • 30
    • 77950284093 scopus 로고    scopus 로고
    • LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer
    • Choi YL, Bocanegra M, Kwon MJ, Shin YK, Nam SJ, Yang JH, et al. LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer. Cancer Res 2010;70:2296-306.
    • (2010) Cancer Res , vol.70 , pp. 2296-2306
    • Choi, Y.L.1    Bocanegra, M.2    Kwon, M.J.3    Shin, Y.K.4    Nam, S.J.5    Yang, J.H.6
  • 31
    • 44849134528 scopus 로고    scopus 로고
    • Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model
    • Park SI, Zhang J, Phillips KA, Araujo JC, Najjar AM, Volgin AY, et al. Targeting SRC family kinases inhibits growth and lymph node metastases of prostate cancer in an orthotopic nude mouse model. Cancer Res 2008;68:3323-33.
    • (2008) Cancer Res , vol.68 , pp. 3323-3333
    • Park, S.I.1    Zhang, J.2    Phillips, K.A.3    Araujo, J.C.4    Najjar, A.M.5    Volgin, A.Y.6
  • 32
    • 77649250977 scopus 로고    scopus 로고
    • STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress
    • Uckun FM, Qazi S, Ma H, Tuel-Ahlgren L, Ozer Z. STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress. Proc Natl Acad Sci U S A 2010;107:2902-7.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 2902-2907
    • Uckun, F.M.1    Qazi, S.2    Ma, H.3    Tuel-Ahlgren, L.4    Ozer, Z.5
  • 33
    • 0348147580 scopus 로고    scopus 로고
    • Grb2 regulates Stat3 activation negatively in epidermal growth factor signalling
    • Zhang T, Ma J, Cao X. Grb2 regulates Stat3 activation negatively in epidermal growth factor signalling. Biochem J 2003;376:457-64.
    • (2003) Biochem J , vol.376 , pp. 457-464
    • Zhang, T.1    Ma, J.2    Cao, X.3
  • 34
    • 33646557326 scopus 로고    scopus 로고
    • P130Cas: A versatile scaffold in signaling networks
    • Defilippi P, Di Stefano P, Cabodi S. p130Cas: a versatile scaffold in signaling networks. Trends Cell Biol 2006;16:257-63.
    • (2006) Trends Cell Biol , vol.16 , pp. 257-263
    • Defilippi, P.1    Di Stefano, P.2    Cabodi, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.