Novel quinolone substituted thiazolidin-4-ones as anti-inflammatory, anticancer agents: Design, synthesis and biological screening

European Journal of Medicinal Chemistry

Volumn 63, Issue , 2013, Pages 589-602

  Suthar, Sharad Kumar ^a   Jaiswal, Varun ^b   Lohan, Sandeep ^a   Bansal, Sumit ^a   Chaudhary, Anil ^a   Tiwari, Amit ^a   Alex, Angel Treasa ^a   Joseph, Alex ^a  

^a MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

^b JAYPEE UNIVERSITY OF INFORMATION TECHNOLOGY   (India)

Author keywords

Anti inflammatory; Anticancer; Docking; NF B; Quinolone; Thiazolidin 4 one

Indexed keywords

3 (4 METHYL 2 OXO 1,2 DIHYDROQUINOLIN 7 YL) 2 (THIOPHEN 2 YL)THIAZOLIDIN 4 ONE; 3 (4 METHYL 2 OXO 1,2 DIHYDROQUINOLIN 7 YL) 2 PHENYLTHIAZOLIDIN 4 ONE; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CARRAGEENAN; CISPLATIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN BAX; PROTEIN BCL 2; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; EHRLICH ASCITES TUMOR; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR DOCKING; MOUSE; NONHUMAN; PAW EDEMA; STRUCTURE ACTIVITY RELATION;

EID: 84875384373     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.03.011     Document Type: Article

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