Characteristics of highly cross-linked polyethylene wear debris in vivo

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 101 B, Issue 3, 2013, Pages 467-475

  Baxter, Ryan M ^a   MacDonald, Daniel W ^a   Kurtz, Steven M ^a,c   Steinbeck, Marla J ^a,b  

^a DREXEL UNIVERSITY   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c EXPONENT INC   (United States)

Author keywords

total hip replacementhighly cross linked polyethyleneosteolysiswear debrisbiological activity

Indexed keywords

CONVENTIONAL POLYETHYLENES; HIGHLY CROSS-LINKED POLYETHYLENE; OSTEOLYTIC POTENTIAL; POLYETHYLENE WEAR; SIGNIFICANT DIFFERENCES; SUB-MICRON PARTICLES; TOTAL HIP ARTHROPLASTY; VOLUME FRACTION DISTRIBUTION;

ARTHROPLASTY; BIOACTIVITY; DEBRIS; SCANNING ELECTRON MICROSCOPY; TISSUE; WEAR RESISTANCE;

POLYETHYLENES;

HIGHLY CROSS LINKED POLYETHYLENE; POLYETHYLENE; UNCLASSIFIED DRUG;

ADULT; AGED; BIOLOGICAL ACTIVITY; COHORT ANALYSIS; CONFERENCE PAPER; DISTRIBUTION VOLUME; FEMALE; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IN VIVO STUDY; INFLAMMATION; MALE; MECHANICAL STRESS; MELTING POINT; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; VOLUMETRY;

AGED; ARTHROPLASTY, REPLACEMENT, HIP; FEMALE; HUMANS; MALE; MATERIALS TESTING; MIDDLE AGED; POLYETHYLENE;

EID: 84875374467     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.32902     Document Type: Conference Paper

References (71)

1. Willert HG, Bertram H, Buchhorn GH,. Osteolysis in alloarthroplasty of the hip. The role of ultra-high molecular weight polyethylene wear particles. Clin Orthop Relat Res 1990 (258): 95-107.
2. Purdue PE, Koulouvaris P, Nestor BJ, Sculco TP,. The central role of wear debris in periprosthetic osteolysis. HSS J 2006; 2 (2): 102-113.
3. Goodman SB,. Wear particles, periprosthetic osteolysis and the immune system. Biomaterials 2007; 28 (34): 5044-5048.
4. Harris WH,. The problem is osteolysis. Clin Orthop Relat Res 1995; 311: 46-53.
5. Harris WH, Muratoglu OK,. A review of current cross-linked polyethylenes used in total joint arthroplasty. Clin Orthop Relat Res 2005;(430): 46-52.
6. Kurtz SM,. The UHMWPE Biomaterials Handbook: Ultra-High Molecular Weight Polyethylene in Total Joint Replacement and Medical Devices. Burlington, MA: Academic Press; 2009.
7. McKellop H, Shen FW, Lu B, Campbell P, Salovey R,. Development of an extremely wear-resistant ultra high molecular weight polyethylene for total hip replacements. J Orthop Res 1999; 17 (2): 157-167.
8. Muratoglu OK, Bragdon CR, O'Connor DO, Jasty M, Harris WH,. A novel method of cross-linking ultra-high-molecular-weight polyethylene to improve wear, reduce oxidation, and retain mechanical properties. Recipient of the 1999 HAP Paul Award. J Arthroplasty 2001; 16 (2): 149-160
9. Oral E, Muratoglu OK,. Radiation cross-linking in ultra-high molecular weight polyethylene for orthopaedic applications. Nucl Instrum Methods Phys Res B 2007; 265 (1): 18-22.
10. Gomez-Barrena E, Medel F, Puertolas JA,. Polyethylene oxidation in total hip arthroplasty: Evolution and new advances. Open Orthop J 2009; 3: 115-120.
11. Kurtz SM, Hozack W, Turner J, Purtill J, MacDonald D, Sharkey P, Parvizi J, Manley M, Rothman R,. Mechanical properties of retrieved highly cross-linked Crossfire liners after short-term implantation. J Arthroplasty 2005; 20 (7): 840-849.
12. Rajadhyaksha AD, Brotea C, Cheung Y, Kuhn C, Ramakrishnan R, Zelicof SB,. Five-year comparative study of highly cross-linked (crossfire) and traditional polyethylene. J Arthroplasty 2009; 24 (2): 161-167.
13. Digas G, Karrholm J, Thanner J, Herberts P., 5-Year experience of highly cross-linked polyethylene in cemented and uncemented sockets: Two randomized studies using radiostereometric analysis. Acta Orthop 2007; 78 (6): 746-754.
14. D'Antonio JA, Manley MT, Capello WN, Bierbaum BE, Ramakrishnan R, Naughton M, Sutton K,. Five-year experience with Crossfire highly cross-linked polyethylene. Clin Orthop Relat Res 2005; 441: 143-150.
15. Olyslaegers C, Defoort K, Simon JP, Vandenberghe L,. Wear in conventional and highly cross-linked polyethylene cups: A 5-year follow-up study. J Arthroplasty 2008; 23 (4): 489-494.
16. Geerdink CH, Grimm B, Ramakrishnan R, Rondhuis J, Verburg AJ, Tonino AJ,. Crosslinked polyethylene compared to conventional polyethylene in total hip replacement: Pre-clinical evaluation, in-vitro testing and prospective clinical follow-up study. Acta Orthop 2006; 77 (5): 719-725.
17. Engh CA, Jr., Stepniewski AS, Ginn SD, Beykirch SE, Sychterz-Terefenko CJ, Hopper RH, Jr., Engh CA,. A randomized prospective evaluation of outcomes after total hip arthroplasty using cross-linked marathon and non-cross-linked Enduron polyethylene liners. J Arthroplasty 2006; 21 (6 Suppl 2): 17-25.
18. Rohrl SM, Li MG, Nilsson KG, Nivbrant B,. Very low wear of non-remelted highly cross-linked polyethylene cups: An RSA study lasting up to 6 years. Acta Orthop 2007; 78 (6): 739-745.
19. Geerdink CH, Grimm B, Vencken W, Heyligers IC, Tonino AJ,. Cross-linked compared with historical polyethylene in THA: An 8-year clinical study. Clin Orthop Relat Res 2009; 467 (4): 979-984.
20. Kurtz SM, Austin MS, Azzam K, Sharkey PF, MacDonald DW, Medel FJ, Hozack WJ,. Mechanical properties, oxidation, and clinical performance of retrieved highly cross-linked Crossfire liners after intermediate-term implantation. J Arthroplasty 2010; 25 (4): 614-623 e 1-2.
21. Kurtz SM, Gawel HA, Patel J,. History and systematic review of wear and osteolysis outcomes for first-generation highly crosslinked polyethylene. Clin Orthop Relat Res 2011; 469: 2262-2277.
22. Langlois J, Hamadouche M,. New animal models of wear-particle osteolysis. Int Orthop 2011; 35 (2): 245-251.
23. Costa L, Luda MP, Trossarelli L, Brach del Prever EM, Crova M, Gallinaro P. Oxidation in orthopaedic UHMWPE sterilized by gamma-radiation and ethylene oxide. Biomaterials 1998; 19 (7-9): 659-668.
24. Kurtz SM, Hozack WJ, Purtill JJ, Marcolongo M, Kraay MJ, Goldberg VM, Sharkey PF, Parvizi J, Rimnac CM, Edidin AA., 2006 Otto Aufranc Award Paper: Significance of in vivo degradation for polyethylene in total hip arthroplasty. Clin Orthop Relat Res 2006; 453: 47-57.
25. Maitra R, Clement CC, Crisi GM, Cobelli N, Santambrogio L,. Immunogenecity of modified alkane polymers is mediated through TLR1/2 activation. PLoS One 2008; 3 (6): e2438.
26. Ferroni D, Quaglini V,. Thermal stabilization of highly crosslinked UHMWPE: A comparative study between annealed and remelted resins. J Appl Biomater Biomech 2010; 8 (2): 82-88.
27. Pruitt LA,. Deformation, yielding, fracture and fatigue behavior of conventional and highly cross-linked ultra high molecular weight polyethylene. Biomaterials 2005; 26 (8): 905-915.
28. Oral E, Malhi AS, Muratoglu OK,. Mechanisms of decrease in fatigue crack propagation resistance in irradiated and melted UHMWPE. Biomaterials 2006; 27 (6): 917-925.
29. Tower SS, Currier JH, Currier BH, Lyford KA, Van Citters DW, Mayor MB,. Rim cracking of the cross-linked longevity polyethylene acetabular liner after total hip arthroplasty. J Bone Joint Surg Am 2007; 89 (10): 2212-2217.
30. Furmanski J, Anderson M, Bal S, Greenwald AS, Halley D, Penenberg B, Ries M, Pruitt L,. Clinical fracture of cross-linked UHMWPE acetabular liners. Biomaterials 2009; 30 (29): 5572-5582.
31. Schroder DT, Kelly NH, Wright TM, Parks ML,. Retrieved highly crosslinked UHMWPE acetabular liners have similar wear damage as conventional UHMWPE. Clin Orthop Relat Res 2011; 469 (2): 387-394.
32. Bradford L, Kurland R, Sankaran M, Kim H, Pruitt LA, Ries MD,. Early failure due to osteolysis associated with contemporary highly cross-linked ultra-high molecular weight polyethylene. A case report. J Bone Joint Surg Am 2004; 86-A (5): 1051-1056.
33. Minoda Y, Kobayashi A, Sakawa A, Aihara M, Tada K, Sugama R, Iwakiri K, Ohashi H, Takaoka K,. Wear particle analysis of highly crosslinked polyethylene isolated from a failed total hip arthroplasty. J Biomed Mater Res B Appl Biomater 2008; 86B (2): 501-505.
34. Endo MM, Barbour PS, Barton DC, Fisher J, Tipper JL, Ingham E, Stone MH,. Comparative wear and wear debris under three different counterface conditions of crosslinked and non-crosslinked ultra high molecular weight polyethylene. Biomed Mater Eng 2001; 11 (1): 23-35.
35. Yamamoto K, Clarke IC, Masaoka T, Oonishi H, Williams PA, Good VD, Imakiire A,. Microwear phenomena of ultrahigh molecular weight polyethylene cups and debris morphology related to gamma radiation dose in simulator study. J Biomed Mater Res 2001; 56 (1): 65-73.
36. Saikko V, Calonius O, Keranen J,. Wear of conventional and cross-linked ultra-high-molecular-weight polyethylene acetabular cups against polished and roughened CoCr femoral heads in a biaxial hip simulator. J Biomed Mater Res 2002; 63 (6): 848-853.
37. Cho DR, Shanbhag AS, Hong C, Baran GR, Goldring SR,. The role of adsorbed endotoxin in particle-induced stimulation of cytokine release. J Orthop Res 2002; 20 (4): 704-713.
38. Oonishi H, Clarke IC, Yamamoto K, Masaoka T, Fujisawa A, Masuda S,. Assessment of wear in extensively irradiated UHMWPE cups in simulator studies. J Biomed Mater Res A 2004; 68 (1): 52-60.
39. Affatato S, Bersaglia G, Rocchi M, Taddei P, Fagnano C, Toni A,. Wear behaviour of cross-linked polyethylene assessed in vitro under severe conditions. Biomaterials 2005; 26 (16): 3259-3267.
40. Williams PA, Oonishi H, Clarke IC,. Highly crosslinked polyethylenes in hip replacements: Improved wear performance or paradox? STLE Tribol Trans 2007; 50 (2): 277-290.
41. Bowsher JG, Williams PA, Clarke IC, Green DD, Donaldson TK., "Severe" wear challenge to 36 mm mechanically enhanced highly crosslinked polyethylene hip liners. J Biomed Mater Res B Appl Biomater 2008; 86 (1): 253-263.
42. Burroughs BR, Rubash HE, Estok D, Jasty M, Krevolin J, Muratoglu OK,. Comparison of conventional and highly crosslinked UHMWPE patellae evaluated by a new in vitro patellofemoral joint simulator. J Biomed Mater Res B Appl Biomater 2006; 79 (2): 268-274.
43. Utzschneider S, Paulus A, Datz JC, Schroeder C, Sievers B, Wegener B, Jansson V,. Influence of design and bearing material on polyethylene wear particle generation in total knee replacement. Acta Biomater 2009; 5 (7): 2495-2502.
44. Teramura S, Sakoda H, Terao T, Endo MM, Fujiwara K, Tomita N,. Reduction of wear volume from ultrahigh molecular weight polyethylene knee components by the addition of vitamin E. J Orthop Res 2008; 26 (4): 460-464.
45. Scott M, Morrison M, Mishra SR, Jani S,. Particle analysis for the determination of UHMWPE wear. J Biomed Mater Res B Appl Biomater 2005; 73 (2): 325-337.
46. Ries MD, Scott ML, Jani S,. Relationship between gravimetric wear and particle generation in hip simulators: Conventional compared with cross-linked polyethylene. J Bone Joint Surg Am 2001; 83-A (Suppl 2 Pt 2): 116-122.
47. Illgen RL II, Forsythe TM, Pike JW, Laurent MP, Blanchard CR,. Highly crosslinked vs conventional polyethylene particles-An in vitro comparison of biologic activities. J Arthroplasty 2008; 23 (5): 721-731.
48. Sabokbar A, Fujikawa Y, Neale S, Murray DW, Athanasou NA,. Human arthroplasty derived macrophages differentiate into osteoclastic bone resorbing cells. Ann Rheum Dis 1997; 56 (7): 414-420.
49. Green TR, Fisher J, Stone M, Wroblewski BM, Ingham E,. Polyethylene particles of a 'critical size' are necessary for the induction of cytokines by macrophages in vitro. Biomaterials 1998; 19 (24): 2297-2302.
50. Green TR, Fisher J, Matthews JB, Stone MH, Ingham E,. Effect of size and dose on bone resorption activity of macrophages by in vitro clinically relevant ultra high molecular weight polyethylene particles. J Biomed Mater Res 2000; 53 (5): 490-497.
51. Urban RM, Jacobs JJ, Tomlinson MJ, Gavrilovic J, Black J, Peoc'h M,. Dissemination of wear particles to the liver, spleen, and abdominal lymph nodes of patients with hip or knee replacement. J Bone Joint Surg Am 2000; 82 (4): 457-476 (see comment).
52. Margevicius KJ, Bauer TW, McMahon JT, Brown SA, Merritt K,. Isolation and characterization of debris in membranes around total joint prostheses. J Bone Joint Surg Am 1994; 76 (11): 1664-1675.
53. Baxter RM, Steinbeck MJ, Tipper JL, Parvizi J, Marcolongo M, Kurtz SM,. Comparison of periprosthetic tissue digestion methods for ultra-high molecular weight polyethylene wear debris extraction. J Biomed Mater Res B Appl Biomater 2009; 91 (1): 409-418.
54. Lapcikova M, Slouf M, Dybal J, Zolotarevova E, Entlicher G, Pokorny D, Gallo J, Sosna A,. Nanometer size wear debris generated from ultrahigh molecular weight polyethylene in vivo. Wear 2009; 266: 349-355.
55. F1877-05e Standard Practice for Characterization of Particles. ASTM International, 100 Barr Harbor Drive, PO Box C700, West Conshohocken, PA, 19428-2959 USA; 2005.
56. Fisher J, Bell J, Barbour PS, Tipper JL, Matthews JB, Besong AA, Stone MH, Ingham E,. A novel method for the prediction of functional biological activity of polyethylene wear debris. Proc Inst Mech Eng H 2001; 215 (2): 127-132.
57. Matthews JB, Besong AA, Green TR, Stone MH, Wroblewski BM, Fisher J, Ingham E,. Evaluation of the response of primary human peripheral blood mononuclear phagocytes to challenge with in vitro generated clinically relevant UHMWPE particles of known size and dose. J Biomed Mater Res 2000; 52 (2): 296-307.
58. Baxter RM, MacDonald DW, Kurtz SM, Steinbeck MJ,. Severe impingement of lumbar disc arthroplasty increases the functional biologic activity of polyethylene wear debris. J Bone Joint Surg Am-In Press.
59. Scott M, Widding K, Jani S,. Do current wear particle isolation procedures underestimate the number of particles generated by prosthetic bearing components? Wear 2001; 251: 1213-1217.
60. Mirra JM, Amstutz HC, Matos M, Gold R,. The pathology of the joint tissues and its clinical relevance in prosthesis failure. Clin Orthop 1976; 117: 221-240.
61. Tipper JL,. The Biological Response to Nanometre-Sized Particles, Torino, Italy, 17 September; 2009.
62. Howling GI, Barnett PI, Tipper JL, Stone MH, Fisher J, Ingham E,. Quantitative characterization of polyethylene debris isolated from periprosthetic tissue in early failure knee implants and early and late failure Charnley hip implants. J Biomed Mater Res 2001; 58 (4): 415-420.
63. Gallo J, Slouf M, Goodman SB,. The relationship of polyethylene wear to particle size, distribution, and number: A possible factor explaining the risk of osteolysis after hip arthroplasty. J Biomed Mater Res B Appl Biomater 2010; 94 (1): 171-177.
64. Revell PA,. The biological effects of nanoparticles. Nanotechnol Perceptions 2006; 2: 283-298.
65. Iwakiri K, Minoda Y, Kobayashi A, Iwaki H, Inori F, Ohashi H, Ohta Y, Fukunaga K, Takaoka K,. In vivo comparison of wear particles between highly crosslinked polyethylene and conventional polyethylene in the same design of total knee arthroplasties. J Biomed Mater Res B Appl Biomater 2009; 91: 799-804.
66. Endo M, Tipper JL, Barton DC, Stone MH, Ingham E, Fisher J,. Comparison of wear, wear debris and functional biological activity of moderately crosslinked and non-crosslinked polyethylenes in hip prostheses. Proc Inst Mech Eng H 2002; 216 (2): 111-122.
67. Saikko V, Calonius O, Keranen J,. Effect of counterface roughness on the wear of conventional and crosslinked ultrahigh molecular weight polyethylene studied with a multi-directional motion pin-on-disk device. J Biomed Mater Res 2001; 57 (4): 506-512.
68. Wang A,. A unified theory of wear for ultra-high molecular weight polyethylene in multi-directional sliding. Wear 2001; 248 (1-2): 38-47.
69. Ren W, Yang SY, Fang HW, Hsu S, Wooley PH,. Distinct gene expression of receptor activator of nuclear factor-kappaB and rank ligand in the inflammatory response to variant morphologies of UHMWPE particles. Biomaterials 2003; 24 (26): 4819-4826.
70. Yang SY, Ren W, Park Y, Sieving A, Hsu S, Nasser S, Wooley PH,. Diverse cellular and apoptotic responses to variant shapes of UHMWPE particles in a murine model of inflammation. Biomaterials 2002; 23 (17): 3535-3543.
71. Galvin AL, Tipper JL, Jennings LM, Stone MH, Jin ZM, Ingham E, Fisher I,. Wear and biological activity of highly crosslinked polyethylene in the hip under low serum protein concentrations. Proc Inst Mech Eng H 2007; 221 (1): 1-10.