Genomic, transcriptomic, and lipidomic profiling highlights the role of inflammation in individuals with low high-density lipoprotein cholesterol

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 33, Issue 4, 2013, Pages 847-857

  Laurila, Pirkka Pekka ^a,b   Surakka, Ida ^a,b   Sarin, Antti Pekka ^a,b   Yetukuri, Laxman ^c   Hyötyläinen, Tuulia ^c   Söderlund, Sanni ^d   Naukkarinen, Jussi ^b   Tang, Jing ^c   Kettunen, Johannes ^a,b   Mirel, Daniel B ⁱ   Soronen, Jarkko ^b   Lehtimäki, Terho ^l   Ruokonen, Aimo ^m   Ehnholm, Christian ^b   Eriksson, Johan G ^a,b,d,j,k   Salomaa, Veikko ^b   Jula, Antti ^b   Raitakari, Olli T ^f,g   Järvelin, Marjo Riitta ^b,e,m   Palotie, Aarno ^a,h,i   Peltonen, Leena ⁿ   Orešič, Matej ^c   Jauhiainen, Matti ^b   Taskinen, Marja Riitta ^d   Ripatti, Samuli ^a,b,h   more..

^a UNIVERSITY OF HELSINKI   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c VTT TECHNICAL RESEARCH CENTRE OF FINLAND   (Finland)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF TURKU   (Finland)

^g TURKU UNIVERSITY HOSPITAL   (Finland)

^h WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

ⁱ BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^j FOLKHÄLSAN RESEARCH CENTER   (Finland)

^k VAASA CENTRAL HOSPITAL   (Finland)

^l TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^m UNIVERSITY OF OULU   (Finland)

ⁿ National Institute for Health and Welfare ^*

more..

Author keywords

coronary artery disease; genome wide association; genomics; HDL cholesterol; inflammation; lipidomics; transcriptomics

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PLASMALOGEN; VASCULAR CELL ADHESION MOLECULE 1;

ADIPOSE TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FINLAND; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOMICS; GENOTYPE; HLA TYPING; HUMAN; INFLAMMATION; LIPIDOMICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; QUANTITATIVE TRAIT; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTOMICS; UPREGULATION; VASCULITIS;

ADIPOSE TISSUE; BIOLOGICAL MARKERS; CHOLESTEROL, HDL; CORONARY ARTERY DISEASE; FEMALE; FINLAND; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; HEALTH SURVEYS; HLA ANTIGENS; HUMANS; INFLAMMATION; LINEAR MODELS; LOGISTIC MODELS; MALE; MIDDLE AGED; PHENOTYPE; PLASMALOGENS; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; RISK FACTORS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84875372535     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.300733     Document Type: Article

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