A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol

PLoS Genetics

Volumn 7, Issue 10, 2011, Pages

  Surakka, Ida ^a,b   Isaacs, Aaron ^c,d   Karssen, Lennart C ^c   Laurila, Pirkka Pekka P ^a,b,e   Middelberg, Rita P S ^f,g   Tikkanen, Emmi ^a,b   Ried, Janina S ^h   Lamina, Claudia ⁱ   Mangino, Massimo ^j   Igl, Wilmar ^k   Hottenga, Jouke Jan ^l   Lagou, Vasiliki ^m,n   van der Harst, Pim ^o   Leach, Irene ^o   Esko, Tõnu ^p,q   Kutalik, Zoltán ^r,s   Wainwright, Nicholas W ^t,u   Struchalin, Maksim V ^c   Sarin, Antti Pekka ^a,b   Kangas, Antti J ^v   Viikari, Jorma S ^w   Perola, Markus ^a,b,p   Rantanen, Taina ^x   Petersen, Ann Kristin ^h   Soininen, Pasi ^y   Johansson, Åsa ^k   Soranzo, Nicole ^j,t   Heath, Andrew C ^z   Papamarkou, Theodore ^t,u   Prokopenko, Inga ^m,n   Tönjes, Anke ^aa   Kronenberg, Florian ⁱ   Döring, Angela ^h   Rivadeneira, Fernando ^c,d   Montgomery, Grant W ^f   Whitfield, John B ^f   Kähönen, Mika ^ab,ac   Lehtimäki, Terho ^ab,ac   Freimer, Nelson B ^ad,ae   Willemsen, Gonneke ^l   de Geus, Eco J C ^l   Palotie, Aarno ^a,e,t,af   Sandhu, Manj S ^t,u   Waterworth, Dawn M ^ag   Metspalu, Andres ^p,q   Stumvoll, Michael ^aa   Uitterlinden, André G ^c,d   Jula, Antti ^b   Navis, Gerjan ^o   Wijmenga, Cisca ^o   Wolffenbuttel, Bruce H R ^o   Taskinen, Marja Riitta ^ah   Ala Korpela, Mika ^v,y   Kaprio, Jaakko ^a,b   Kyvik, Kirsten O ^ai,aj   Boomsma, Dorret I ^l   Pedersen, Nancy L ^ak   Gyllensten, Ulf ^k   Wilson, James F ^al   Rudan, Igor ^al,am   Campbell, Harry ^al   Pramstaller, Peter P ^an,ao,ap   Spector, Tim D ^j   Witteman, Jacqueline C M ^c,d   Eriksson, Johan G ^a,b,ah,aq,ar   Salomaa, Veikko ^b   Oostra, Ben A ^c   Raitakari, Olli T ^w,as   Wichmann, H Erich ^h,at,au   Gieger, Christian ^h   Järvelin, Marjo Riitta ^av   Martin, Nicholas G ^f   Hofman, Albert ^c,d   McCarthy, Mark I ^m,n,aw   Peltonen, Leena ^a,b,e,r,af   van Duijn, Cornelia M ^c,d   Aulchenko, Yurii S ^c   Ripatti, Samuli ^a,b,t   more..

^a UNIVERSITY OF HELSINKI   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d Netherlands Genomics Initiative   (Netherlands)

^e UNIVERSITY OF HELSINKI   (Finland)

^f QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^g THE PRINCE CHARLES HOSPITAL   (Australia)

^h INSTITUTE OF EPIDEMIOLOGY   (Germany)

ⁱ INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^j KING'S COLLEGE LONDON   (United Kingdom)

^k UPPSALA UNIVERSITY   (Sweden)

^l VU UNIVERSITY AMSTERDAM   (Netherlands)

^m UNIVERSITY OF OXFORD   (United Kingdom)

ⁿ UNIVERSITY OF OXFORD   (United Kingdom)

^o UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^p UNIVERSITY OF TARTU   (Estonia)

^q UNIVERSITY OF TARTU   (Estonia)

^r UNIVERSITY OF LAUSANNE   (Switzerland)

^s SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^t WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^u UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^v UNIVERSITY OF OULU   (Finland)

^w UNIVERSITY OF TURKU   (Finland)

^x UNIVERSITY OF JYVÄSKYLÄ   (Finland)

^y UNIVERSITY OF EASTERN FINLAND   (Finland)

^z WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^aa UNIVERSITY OF LEIPZIG   (Germany)

^ab TAMPERE UNIVERSITY HOSPITAL   (Finland)

^ac TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^ad UNIVERSITY OF CALIFORNIA   (United States)

^ae UNIVERSITY OF CALIFORNIA   (United States)

^af BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^ag GLAXOSMITHKLINE   (United States)

^ah HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^ai UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^aj ODENSE UNIVERSITY HOSPITAL   (Denmark)

^ak KAROLINSKA INSTITUTE   (Sweden)

^al UNIVERSITY OF EDINBURGH   (United Kingdom)

^am UNIVERSITY OF SPLIT   (Croatia)

^an INSTITUTE FOR RENEWABLE ENERGY   (Italy)

^ao UNIVERSITY OF LÜBECK   (Germany)

^ap CENTRAL HOSPITAL OF BOLZANO   (Italy)

^aq FOLKHÄLSAN RESEARCH CENTER   (Finland)

^ar VAASA CENTRAL HOSPITAL   (Finland)

^as UNIVERSITY OF TURKU   (Finland)

^at UNIVERSITY OF MUNICH   (Germany)

^au LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^av IMPERIAL COLLEGE LONDON   (United Kingdom)

^aw CHURCHILL HOSPITAL   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; CHOLESTEROL; GUANOSINE; LIPOPROTEIN; CADHERIN; LIPID; PCDH7 PROTEIN, HUMAN; TRIACYLGLYCEROL;

ADULT; ALLELE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DNA MODIFICATION; EUROPE; GENE DOSAGE; GENE EXPRESSION PROFILING; GENE INTERACTION; GENE LOCUS; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SCREENING; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HOMOZYGOSITY; HUMAN; RISK FACTOR; WAIST HIP RATIO; ADIPOSE TISSUE; BLOOD; BODY FAT DISTRIBUTION; CAUCASIAN; CHROMOSOME 4; CHROMOSOME MAP; GENETICS; METABOLISM; PHENOTYPE; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM;

ADIPOSE TISSUE; BODY FAT DISTRIBUTION; CADHERINS; CHOLESTEROL; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 4; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; LIPIDS; LIPOPROTEINS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; RISK FACTORS; TRIGLYCERIDES; WAIST-HIP RATIO;

EID: 80055066037     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002333     Document Type: Article

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