Inflammation modulates human HDL composition and function in vivo

Atherosclerosis

Volumn 222, Issue 2, 2012, Pages 390-394

  de la Llera Moya, Margarita ^a   McGillicuddy, Fiona C ^b,c   Hinkle, Christine C ^b   Byrne, Michael ^b   Joshi, Michelle R ^a   Nguyen, Vihn ^a   Tabita Martinez, Jennifer ^b   Wolfe, Megan L ^b   Badellino, Karen ^b   Pruscino, Leticia ^b   Mehta, Nehal N ^b   Asztalos, Bela F ^d   Reilly, Muredach P ^b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

^d TUFTS UNIVERSITY   (United States)

Author keywords

Atherosclerosis; Cholesterol; Inflammation; Lipoproteins; Macrophages

Indexed keywords

ABC TRANSPORTER A1; ABC TRANSPORTER G1; CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; HIGH DENSITY LIPOPROTEIN; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE A2; SCAVENGER RECEPTOR BI;

ADULT; ARTICLE; CHOLESTEROL TRANSPORT; ENDOTOXEMIA; ENZYME ACTIVITY; FEMALE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MALE; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ADULT; ANIMALS; APOLIPOPROTEIN A-I; ATP BINDING CASSETTE TRANSPORTER 1; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL, HDL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENDOTOXEMIA; FEMALE; GROUP II PHOSPHOLIPASES A2; HIGH-DENSITY LIPOPROTEINS, PRE-BETA; HUMANS; INFLAMMATION; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; PARTICLE SIZE; PHOSPHATIDYLCHOLINE-STEROL O-ACYLTRANSFERASE; RATS; SCAVENGER RECEPTORS, CLASS B; TIME FACTORS; YOUNG ADULT;

EID: 84861347399     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.02.032     Document Type: Article

References (34)

1. Wang X., Rader D.J. Molecular regulation of macrophage reverse cholesterol transport. Curr Opin Cardiol 2007, 22:368-372.
2. van der Westhuyzen D.R., de Beer F.C., Webb N.R. HDL cholesterol transport during inflammation. Curr Opin Lipidol 2007, 18:147-151.
3. Khovidhunkit W., Kim M.S., Memon R.A., et al. Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host. J Lipid Res 2004, 45:1169-1196.
4. Hudgins L.C., Parker T.S., Levine D.M., et al. A single intravenous dose of endotoxin rapidly alters serum lipoproteins and lipid transfer proteins in normal volunteers. J Lipid Res 2003, 44:1489-1498.
5. Levels J.H., Pajkrt D., Schultz M., et al. Alterations in lipoprotein homeostasis during human experimental endotoxemia and clinical sepsis. Biochim Biophys Acta 2007, 1771:1429-1438.
6. Memon R.A., Grunfeld C., Moser A.H., Feingold K.R. Tumor necrosis factor mediates the effects of endotoxin on cholesterol and triglyceride metabolism in mice. Endocrinology 1993, 132:2246-2253.
7. Paradis M.E., Badellino K.O., Rader D.J., et al. Endothelial lipase is associated with inflammation in humans. J Lipid Res 2006, 47:2808-2813.
8. de Beer F.C., Connell P.M., Yu J., de Beer M.C., Webb N.R., van der Westhuyzen D.R. HDL modification by secretory phospholipase A(2) promotes scavenger receptor class B type I interaction and accelerates HDL catabolism. J Lipid Res 2000, 41:1849-1857.
9. Jahangiri A., de Beer M.C., Noffsinger V., et al. HDL remodeling during the acute phase response. Arterioscler Thromb Vasc Biol 2009, 29:261-267.
10. Khovidhunkit W., Moser A.H., Shigenaga J.K., Grunfeld C., Feingold K.R. Regulation of scavenger receptor class B type I in hamster liver and Hep3B cells by endotoxin and cytokines. J Lipid Res 2001, 42:1636-1644.
11. McGillicuddy F.C., de la Llera Moya M., Hinkle C.C., et al. Inflammation impairs reverse cholesterol transport in vivo. Circulation 2009, 119:1135-1145.
12. Grunfeld C., Pang M., Doerrler W., Shigenaga J.K., Jensen P., Feingold K.R. Lipids, lipoproteins, triglyceride clearance, and cytokines in human immunodeficiency virus infection and the acquired immunodeficiency syndrome. J Clin Endocrinol Metab 1992, 74:1045-1052.
13. Fong Y.M, Marano M.A., Barber A., et al. Total parenteral nutrition and bowel rest modify the metabolic response to endotoxin in humans. Ann Surg 1989, 210:449-456. discussion 456-447.
14. Malik P., Berisha S.Z., Santore J., Agatisa-Boyle C., Brubaker G., Smith J.D. Zymosan-mediated inflammation impairs in vivo reverse cholesterol transport. J Lipid Res 2011, 52:951-957.
15. Smoak K.A., Aloor J.J., Madenspacher J., et al. Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation. Cell Metab 2010, 11:493-502.
16. Mehta N.N., McGillicuddy F.C., Anderson P.D., et al. Experimental endotoxemia induces adipose inflammation and insulin resistance in humans. Diabetes 2010, 59:172-181.
17. Badellino K.O., Wolfe M.L., Reilly M.P., Rader D.J. Endothelial lipase is increased in vivo by inflammation in humans. Circulation 2008, 117:678-685.
18. Tietge U.J., Maugeais C., Lund-Katz S., Grass D., deBeer F.C., Rader D.J. Human secretory phospholipase A2 mediates decreased plasma levels of HDL cholesterol and apoA-I in response to inflammation in human apoA-I transgenic mice. Arterioscler Thromb Vasc Biol 2002, 22:1213-1218.
19. Schunkert H., Konig I.R., Kathiresan S., et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 2011, 43:333-338.
20. Barter P.J., Caulfield M., Eriksson M., et al. Effects of torcetrapib in patients at high risk for coronary events. N Engl J Med 2007, 357:2109-2122.
21. Agwunobi A.O., Reid C., Maycock P., Little R.A., Carlson G.L. Insulin resistance and substrate utilization in human endotoxemia. J Clin Endocrinol Metab 2000, 85:3770-3778.
22. Copeland S., Warren H.S., Lowry S.F., Calvano S.E., Remick D. Acute inflammatory response to endotoxin in mice and humans. Clin Diagn Lab Immunol 2005, 12:60-67.
23. Shah R., Lu Y., Hinkle C.C., et al. Gene profiling of human adipose tissue during evoked inflammation in vivo. Diabetes 2009, 58:2211-2219.
24. Suffredini A.F., Fantuzzi G., Badolato R., Oppenheim J.J., O'Grady N.P. New insights into the biology of the acute phase response. J Clin Immunol 1999, 19:203-214.
25. Shi H., Kokoeva M.V., Inouye K., Tzameli I., Yin H., Flier J.S. TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 2006, 116:3015-3025.
26. Feingold K.R., Hardardottir I., Memon R., et al. Effect of endotoxin on cholesterol biosynthesis and distribution in serum lipoproteins in Syrian hamsters. J Lipid Res 1993, 34:2147-2158.
27. Feingold K.R., Memon R.A., Moser A.H., Shigenaga J.K., Grunfeld C. Endotoxin and interleukin-1 decrease hepatic lipase mRNA levels. Atherosclerosis 1999, 142:379-387.
28. Pruzanski W., Stefanski E., de beer F.C., et al. Lipoproteins are substrates for human secretory group IIA phospholipase A2: preferential hydrolysis of acute phase HDL. J Lipid Res 1998, 39:2150-2160.
29. Duong M., Psaltis M., Rader D.J., Marchadier D., Barter P.J., Rye K.A. Evidence that hepatic lipase and endothelial lipase have different substrate specificities for high-density lipoprotein phospholipids. Biochemistry 2003, 42:13778-13785.
30. Asztalos B.F., Sloop C.H., Wong L., Roheim P.S. Two-dimensional electrophoresis of plasma lipoproteins: recognition of new apo A-I-containing subpopulations. Biochim Biophys Acta 1993, 1169:291-300.
31. Asztalos B.F., Schaefer E.J., Horvath K.V., et al. Role of LCAT in HDL remodeling: investigation of LCAT deficiency states. J Lipid Res 2007, 48:592-599.
32. Asztalos B.F., de la Llera-Moya M., Dallal G.E., Horvath K.V., Schaefer E.J., Rothblat G.H. Differential effects of HDL subpopulations on cellular ABCA1- and SR-BI-mediated cholesterol efflux. J Lipid Res 2005, 46:2246-2253.
33. de Beer M.C., Ji A., Jahangiri A., et al. ATP binding cassette G1-dependent cholesterol efflux during inflammation. J Lipid Res 2010, 52:345-353.
34. Khera A.V., Cuchel M., de la Llera-Moya M., et al. Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosis. New Engl J Med 2011, 364:127-135.