-
1
-
-
0033031331
-
COX-2 inhibitors
-
C.J. Hawkey COX-2 inhibitors Lancet 353 1999 307 314
-
(1999)
Lancet
, vol.353
, pp. 307-314
-
-
Hawkey, C.J.1
-
2
-
-
0025754779
-
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
-
W.L. Xie, J.G. Chipman, D.L. Robertson, R.L. Erikson, and D.L. Simmons Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing Proc. Natl. Acad. Sci. U.S.A. 88 1991 2692 2696
-
(1991)
Proc. Natl. Acad. Sci. U.S.A.
, vol.88
, pp. 2692-2696
-
-
Xie, W.L.1
Chipman, J.G.2
Robertson, D.L.3
Erikson, R.L.4
Simmons, D.L.5
-
3
-
-
77952554514
-
Thinking outside the box about COX-1 in Alzheimer's disease
-
S.A. Frautschy Thinking outside the box about COX-1 in Alzheimer's disease Neurobiol. Dis. 38 2010 492 494
-
(2010)
Neurobiol. Dis.
, vol.38
, pp. 492-494
-
-
Frautschy, S.A.1
-
4
-
-
77951620638
-
The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1
-
J.L. Teeling, C. Cunningham, T.A. Newman, and V.H. Perry The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: implications for a role of COX-1 Brain Behav. Immun. 24 2010 409 419
-
(2010)
Brain Behav. Immun.
, vol.24
, pp. 409-419
-
-
Teeling, J.L.1
Cunningham, C.2
Newman, T.A.3
Perry, V.H.4
-
5
-
-
58949086472
-
Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole- 1-yl)-methanesulfonylphenyl derivatives
-
F. Wuest, X. Tang, T. Kniess, J. Pietzsch, and M. Suresh Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)- methanesulfonylphenyl derivatives Bioorg. Med. Chem. 17 2009 1146 1151
-
(2009)
Bioorg. Med. Chem.
, vol.17
, pp. 1146-1151
-
-
Wuest, F.1
Tang, X.2
Kniess, T.3
Pietzsch, J.4
Suresh, M.5
-
6
-
-
58549091464
-
Diaryl-dithiolanes and -isothiazoles: COX-1/COX-2 and 5-LOX-inhibitory, OH scavenging and anti-adhesive activities
-
M. Scholz, H.K. Ulbrich, and O. Soehnlein Diaryl-dithiolanes and -isothiazoles: COX-1/COX-2 and 5-LOX-inhibitory, OH scavenging and anti-adhesive activities Bioorg. Med. Chem. 17 2009 558 568
-
(2009)
Bioorg. Med. Chem.
, vol.17
, pp. 558-568
-
-
Scholz, M.1
Ulbrich, H.K.2
Soehnlein, O.3
-
8
-
-
0032789047
-
Selective cyclooxygenase-2 inhibitors as non-ulcerogenic anti-inflammatory agents
-
A.S. Kalgutkar Selective cyclooxygenase-2 inhibitors as non-ulcerogenic anti-inflammatory agents Exp. Opin. Ther. Patents 8 1999 831 849
-
(1999)
Exp. Opin. Ther. Patents
, vol.8
, pp. 831-849
-
-
Kalgutkar, A.S.1
-
9
-
-
13444266910
-
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5-(4-methylphenyl)-3- (trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC-58635, Celecoxib)
-
T.D. Penning, J.J. Talley, and S.R. Bertenshaw Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide (SC-58635, Celecoxib) J. Med. Chem. 40 1997 1347 1365
-
(1997)
J. Med. Chem.
, vol.40
, pp. 1347-1365
-
-
Penning, T.D.1
Talley, J.J.2
Bertenshaw, S.R.3
-
10
-
-
77549086418
-
Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor
-
H. Kakuta, R. Fukai, and X. Zheng Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor Bioorg. Med. Chem. Lett. 20 2010 1840 1843
-
(2010)
Bioorg. Med. Chem. Lett.
, vol.20
, pp. 1840-1843
-
-
Kakuta, H.1
Fukai, R.2
Zheng, X.3
-
11
-
-
33646490753
-
Anti-angiogenic activity of basic-type, selective cyclooxygenase (COX)-1 inhibitors
-
H. Sano, T. Noguchi, A. Miyajma, Y. Hashimoto, and H. Miyachi Anti-angiogenic activity of basic-type, selective cyclooxygenase (COX)-1 inhibitors Bioorg. Med. Chem. Lett. 16 2006 3068 3072
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 3068-3072
-
-
Sano, H.1
Noguchi, T.2
Miyajma, A.3
Hashimoto, Y.4
Miyachi, H.5
-
12
-
-
16244383547
-
Design and synthesis of subtype-selective cyclooxygenase (COX) inhibitors derived from thalidomide
-
H. Sano, T. Noguchi, A. Tanatni, Y. Hashimoto, and H. Miyachi Design and synthesis of subtype-selective cyclooxygenase (COX) inhibitors derived from thalidomide Bioorg. Med. Chem. 13 2005 3079 3091
-
(2005)
Bioorg. Med. Chem.
, vol.13
, pp. 3079-3091
-
-
Sano, H.1
Noguchi, T.2
Tanatni, A.3
Hashimoto, Y.4
Miyachi, H.5
-
14
-
-
0026788165
-
Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs
-
M.C. Allison, A.G. Howatson, C.J. Torrance, F.D. Lee, and R.I. Russell Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs N. Engl. J. Med. 327 1992 749 754
-
(1992)
N. Engl. J. Med.
, vol.327
, pp. 749-754
-
-
Allison, M.C.1
Howatson, A.G.2
Torrance, C.J.3
Lee, F.D.4
Russell, R.I.5
-
16
-
-
0027345554
-
Microbial pyran-2-ones and dihydropyran-2-ones
-
J.M. Dickinson Microbial pyran-2-ones and dihydropyran-2-ones Nat. Prod. Rep. 10 1993 71 98
-
(1993)
Nat. Prod. Rep.
, vol.10
, pp. 71-98
-
-
Dickinson, J.M.1
-
17
-
-
21244491657
-
2-Pyrone natural products and mimetics: Isolation, characterization and biological activity
-
G.P. McGlacken, and I.J.S Fairlamb 2-Pyrone natural products and mimetics: isolation, characterization and biological activity Nat. Prod. Rep. 22 2005 369 385
-
(2005)
Nat. Prod. Rep.
, vol.22
, pp. 369-385
-
-
McGlacken, G.P.1
Fairlamb, J.S.2
-
18
-
-
0028094959
-
Novel series of achiral, low molecular weight, and potent HIV-1 protease inhibitors
-
J.V.N. Vara Prasad, K.S. Para, and E.A. Lunney Novel series of achiral, low molecular weight, and potent HIV-1 protease inhibitors J. Am. Chem. Soc. 116 1994 6989 6990
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 6989-6990
-
-
Vara Prasad, J.V.N.1
Para, K.S.2
Lunney, E.A.3
-
19
-
-
0141855265
-
Synthetic studies directed toward the assembly of the C-glycoside fragment of the telomerase inhibitor D8646-2-6
-
A. Kanai, T. Kamino, K. Kuramochi, and S. Kobayashi Synthetic studies directed toward the assembly of the C-glycoside fragment of the telomerase inhibitor D8646-2-6 Org. Lett. 5 2003 2837 2839
-
(2003)
Org. Lett.
, vol.5
, pp. 2837-2839
-
-
Kanai, A.1
Kamino, T.2
Kuramochi, K.3
Kobayashi, S.4
-
20
-
-
0027393279
-
Gibepyrones: α-pyrones from Gibberella fujikuroi
-
A.F. Barrero, J.E. Oltra, and M.M. Herrador Gibepyrones: α-pyrones from Gibberella fujikuroi Tetrahedron 49 1993 141 150
-
(1993)
Tetrahedron
, vol.49
, pp. 141-150
-
-
Barrero, A.F.1
Oltra, J.E.2
Herrador, M.M.3
-
21
-
-
0001122915
-
Fusalanipyrone, a monoterpenoid from Fusarium solani
-
W.R. Abraham, and H. Arfmann Fusalanipyrone, a monoterpenoid from Fusarium solani Phytochemistry 27 1988 3310 3311
-
(1988)
Phytochemistry
, vol.27
, pp. 3310-3311
-
-
Abraham, W.R.1
Arfmann, H.2
-
22
-
-
0242439488
-
Viridepyronone, a new antifungal 6-substituted 2H-pyran-2-one produced by Trichoderma viride
-
A. Evidente, A. Cabras, and L. Maddau Viridepyronone, a new antifungal 6-substituted 2H-pyran-2-one produced by Trichoderma viride J. Agric. Food Chem. 51 2003 6957 6960
-
(2003)
J. Agric. Food Chem.
, vol.51
, pp. 6957-6960
-
-
Evidente, A.1
Cabras, A.2
Maddau, L.3
-
25
-
-
0022876824
-
6-Pentyl-α-pyrone from Trichoderma harzianum: Its plant growth inhibitory and antimicrobial properties
-
H.G. Cutler, R.H. Cox, F.G. Crumley, and P.O. Cole 6-Pentyl-α- pyrone from Trichoderma harzianum: its plant growth inhibitory and antimicrobial properties Agric. Biol. Chem. 50 1986 2943 2945
-
(1986)
Agric. Biol. Chem.
, vol.50
, pp. 2943-2945
-
-
Cutler, H.G.1
Cox, R.H.2
Crumley, F.G.3
Cole, P.O.4
-
26
-
-
0014172728
-
Pharmacology and toxicology of toad venom
-
K.K. Chen, and A.J. Kovarikova Pharmacology and toxicology of toad venom J. Pharm. Sci. 56 1967 1535 1541
-
(1967)
J. Pharm. Sci.
, vol.56
, pp. 1535-1541
-
-
Chen, K.K.1
Kovarikova, A.J.2
-
27
-
-
0028833190
-
A new synthesis of alkylated 2H-pyran-2-ones and its application to the determination of the relative and absolute configuration of supellapyrone, sex pheromone of the brownbanded cockroach, Supella longipalpa
-
X. Shi, W.S. Leal, Z. Liu, E. Schrader, and J. Meinwald A new synthesis of alkylated 2H-pyran-2-ones and its application to the determination of the relative and absolute configuration of supellapyrone, sex pheromone of the brownbanded cockroach, Supella longipalpa Tetrahedron Lett. 36 1995 71 74
-
(1995)
Tetrahedron Lett.
, vol.36
, pp. 71-74
-
-
Shi, X.1
Leal, W.S.2
Liu, Z.3
Schrader, E.4
Meinwald, J.5
-
28
-
-
0032558625
-
New α-pyrones produced by fungal culture LL-11G219 function as androgen receptor ligands
-
G. Schlingmann, L. Milne, and G.T. Carter New α-pyrones produced by fungal culture LL-11G219 function as androgen receptor ligands Tetrahedron 54 1998 13013 13022
-
(1998)
Tetrahedron
, vol.54
, pp. 13013-13022
-
-
Schlingmann, G.1
Milne, L.2
Carter, G.T.3
-
29
-
-
0001744466
-
Three new phytotoxins produced by Pyrenochaeta terrestris: Pyrenochaetic acids A, B and C
-
H. Sato, K. Konoma, and S. Sakamura Three new phytotoxins produced by Pyrenochaeta terrestris: pyrenochaetic acids A, B and C Agric. Biol. Chem. 45 1981 1675 1679
-
(1981)
Agric. Biol. Chem.
, vol.45
, pp. 1675-1679
-
-
Sato, H.1
Konoma, K.2
Sakamura, S.3
-
31
-
-
0036890401
-
Bioactive 4-substituted-6-methyl-2-pyrones with promising cytotoxicity against A2780 and K562 cell lines
-
L.R. Marrison, J.M. Dickinson, and I.J.S. Fairlamb Bioactive 4-substituted-6-methyl-2-pyrones with promising cytotoxicity against A2780 and K562 cell lines Bioorg. Med. Chem. Lett. 12 2002 3509 3513
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 3509-3513
-
-
Marrison, L.R.1
Dickinson, J.M.2
Fairlamb, I.J.S.3
-
32
-
-
0038487718
-
Suzuki cross-coupling approaches to the synthesis of bioactive 3-substituted and 5-substituted-4-methoxy-6-methyl-2-pyrones
-
L.R. Marrison, J.M. Dickinson, and I.J.S. Fairlamb Suzuki cross-coupling approaches to the synthesis of bioactive 3-substituted and 5-substituted-4- methoxy-6-methyl-2-pyrones Bioorg. Med. Chem. Lett. 13 2003 2667 2671
-
(2003)
Bioorg. Med. Chem. Lett.
, vol.13
, pp. 2667-2671
-
-
Marrison, L.R.1
Dickinson, J.M.2
Fairlamb, I.J.S.3
-
33
-
-
0242362591
-
Design, synthesis, and biological evaluation of 6-substituted-3-(4- methanesulfonylphenyl)-4-phenylpyran-2-ones: A novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors
-
P.N. Praveen Rao, M. Amini, H. Li, A.G. Habeeb, and E.E. Knaus Design, synthesis, and biological evaluation of 6-substituted-3-(4- methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors J. Med. Chem. 46 2003 4872 4882
-
(2003)
J. Med. Chem.
, vol.46
, pp. 4872-4882
-
-
Praveen Rao, P.N.1
Amini, M.2
Li, H.3
Habeeb, A.G.4
Knaus, E.E.5
-
34
-
-
3242748214
-
Design, synthesis, and structure-activity relationship studies of 3,4,6-triphenylpyran-2-ones as selective cyclooxygenase-2 inhibitors
-
P.N. Praveen Rao, M.J. Uddin, and E.E. Knaus Design, synthesis, and structure-activity relationship studies of 3,4,6-triphenylpyran-2-ones as selective cyclooxygenase-2 inhibitors J. Med. Chem. 47 2004 3972 3990
-
(2004)
J. Med. Chem.
, vol.47
, pp. 3972-3990
-
-
Praveen Rao, P.N.1
Uddin, M.J.2
Knaus, E.E.3
-
35
-
-
73949124308
-
Michael addition-lactonization reaction of electron-deficient alkynes with N-(diphenylmethylene)glycinates: An efficient synthesis of 3-amino-2-pyrone derivatives
-
Q.F. Zhou, Y. Zhu, W.F. Tang, and T. Lu Michael addition-lactonization reaction of electron-deficient alkynes with N-(diphenylmethylene)glycinates: an efficient synthesis of 3-amino-2-pyrone derivatives Synthesis 2010 211 216
-
(2010)
Synthesis
, pp. 211-216
-
-
Zhou, Q.F.1
Zhu, Y.2
Tang, W.F.3
Lu, T.4
-
36
-
-
79952269028
-
Research progress in the synthesis of 2-pyrone derivatives
-
Q.F. Zhou, S. Zhao, X. Wang, and T. Lu Research progress in the synthesis of 2-pyrone derivatives Chin. J. Org. Chem. 30 2010 1652 1663
-
(2010)
Chin. J. Org. Chem.
, vol.30
, pp. 1652-1663
-
-
Zhou, Q.F.1
Zhao, S.2
Wang, X.3
Lu, T.4
-
37
-
-
33646457964
-
Cyclooxygenase inhibitors not inhibit resting lung cancer A549 cell proliferation
-
W. Duan, and L. Zhang Cyclooxygenase inhibitors not inhibit resting lung cancer A549 cell proliferation Prostaglandins Leukot Essent Fatty Acids 74 2006 317 321
-
(2006)
Prostaglandins Leukot Essent Fatty Acids
, vol.74
, pp. 317-321
-
-
Duan, W.1
Zhang, L.2
|