Neuroprotective effects of Cyperus rotundus on SIN-1 induced nitric oxide generation and protein nitration: Ameliorative effect against apoptosis mediated neuronal cell damage

NeuroToxicology

Volumn 34, Issue 1, 2013, Pages 150-159

  Hemanth Kumar, Kandikattu ^a   Tamatam, Anand ^a   Pal, Ajay ^b   Khanum, Farhath ^a  

^a DEFENCE FOOD RESEARCH LABORATORY   (India)

^b CCS HARYANA AGRICULTURAL UNIVERSITY   (India)

Author keywords

3 Nitrotyrosine; Apoptosis; Cyperus rotundus; Human neuronal cells; Neuroprotection; SIN 1 (3 morpholinosydnonimine)

Indexed keywords

3 NITROTYROSINE; CASPASE 3; CATALASE; CYPERUS ROTUNDUS EXTRACT; INDUCIBLE NITRIC OXIDE SYNTHASE; LINSIDOMINE; NITRIC OXIDE; PEROXYNITRITE; PROTEIN BCL 2; SUPEROXIDE DISMUTASE;

APOPTOSIS; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; HUMAN; HUMAN CELL; MEMBRANE DAMAGE; MITOCHONDRIAL MEMBRANE; NERVE CELL LESION; NEUROPROTECTION; NEUROTOXICITY; NITRATION; PRIORITY JOURNAL;

APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CATALASE; CELL DEATH; CELL LINE, TUMOR; CYPERUS; CYTOPROTECTION; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LIPID PEROXIDATION; MOLSIDOMINE; NEURONS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PEROXYNITROUS ACID; PLANT EXTRACTS; PLANTS, MEDICINAL; PROTO-ONCOGENE PROTEINS C-BCL-2; RHIZOME; SUPEROXIDE DISMUTASE; TYROSINE;

EID: 84875264185     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2012.11.002     Document Type: Article

References (50)

1. Ashki N., Hayes K.C., Bao F. The peroxynitrite donor 3-morpholinosydnonimine induces reversible changes in electrophysiological properties of neurons of the guinea-pig spinal cord. Neuroscience 2008, 156:107-117.
2. Barcelos G.R., Angeli J.P., Serpeloni J.M., Grotto D., Rocha B.A., Bastos J.K., et al. Quercetin protects human-derived liver cells against mercury-induced DNA-damage and alterations of the redox status. Mutat Res 2011, 726:109-115.
3. Borner C. The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol Immunol 2003, 39:615-647.
4. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976, 72:248-254.
5. Chaudhary A.K., Nokubo M., Reddy G.R., Yeola S.N., Morrow J.D., Blair I.A., et al. Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver. Science 1994, 265:1580-1582.
6. Chen W., Jia Z., Zhu H., Zhou K., Li Y., Misra H.P. Ethyl pyruvate inhibits peroxynitrite-induced DNA damage and hydroxyl radical generation: implications for neuroprotection. Neurochem Res 2010, 35:336-342.
7. Chinnaiyan A.M., Orth K., O'Rourke K., Duan H., Poirier G.G., Dixit V.M. Molecular ordering of the cell death pathway Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases. J Biol Chem 1996, 271:4573-4576.
8. Cohen G., Dembiec D., Marcus J. Measurement of catalase activity in tissue extracts. Anal Biochem 1970, 34:30-38.
9. Creighton T.E. Proteins: structure and molecular properties 1993, Freeman, New York.
10. Dulebohn R.V., Yi W., Srivastava A., Akoh C.C., Krewer G., Fischer J.G. Effects of blueberry (Vaccinium ashei) on DNA damage, lipid peroxidation, and phase II enzyme activities in rats. J Agric Food Chem 2008, 56:11700-11706.
11. Eiserich J.P., Vossen V., O'Neill C.A., Halliwell B., Cross C.E., van der Vliet A. Molecular mechanisms of damage by excess nitrogen oxides: nitration of tyrosine by gas-phase cigarette smoke. FEBS Lett 1994, 353:53-56.
12. Ha J.H., Lee K.Y., Choi H.C., Cho J., Kang B.S., Lim J.C., et al. Modulation of radioligand binding to the GABA(A)-benzodiazepine receptor complex by a new component from Cyperus rotundus. Biol Pharm Bull 2002, 25:128-130.
13. Hruszkewycz A.M. Lipid peroxidation and mtDNA degeneration. A hypothesis. Mutat Res 1992, 275:243-248.
14. Ischiropoulos H. Biological selectivity and functional aspects of protein tyrosine nitration. Biochem Biophys Res Commun 2003, 305:776-783.
15. Kelm M., Dahmann R., Wink D., Feelisch M. The nitric oxide/superoxide assay Insights into the biological chemistry of the NO/O-2 interaction. J Biol Chem 1997, 272:9922-9932.
16. Kilani-Jaziri S., Neffati A., Limem I., Boubaker J., Skandrani I., Sghair M.B., et al. Relationship correlation of antioxidant and antiproliferative capacity of Cyperus rotundus products towards K562 erythroleukemia cells. Chem Biol Interact 2009, 181:85-94.
17. Kim H.J., Lee K.W., Kim M.S., Lee H.J. Piceatannol attenuates hydrogen-peroxide- and peroxynitrite-induced apoptosis of PC12 cells by blocking down-regulation of Bcl-XL and activation of JNK. J Nutr Biochem 2008, 19:459-466.
18. Kirkinezos I.G., Moraes C.T. Reactive oxygen species and mitochondrial diseases. Semin Cell Dev Biol 2001, 12:449-457.
19. 2 induced human neuronal cell damage via its anti-oxidative and anti-apoptotic machinery. Cell Mol Neurobiol 2012, http://dx.doi.org/10.1007/s10571-012-9865-8.
20. Lachapelle G., Radicioni S.M., Stankiewicz A.R., Mosser D.D. Acute acidification or amiloride treatment suppresses the ability of Hsp70 to inhibit heat-induced apoptosis. Apoptosis 2007, 12:1479-1488.
21. Lanneau D., Brunet M., Frisan E., Solary E., Fontenay M., Garrido C. Heat shock proteins: essential proteins for apoptosis regulation. J Cell Mol Med 2008, 12:743-761.
22. LeBel C.P., Ischiropoulos H., Bondy S.C. Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 1992, 5:227-231.
23. Lee C.H., Hwang D.S., Kim H.G., Oh H., Park H., Cho J.H., et al. Protective effect of Cyperi rhizoma against 6-hydroxydopamine-induced neuronal damage. J Med Food 2010, 13:564-571.
24. Lee C.S., Kim Y.J., Han E.S. Glycyrrhizin protection against 3-morpholinosydnonime-induced mitochondrial dysfunction and cell death in lung epithelial cells. Life Sci 2007, 80:1759-1767.
25. Lee M.S., Lee J., Kwon D.Y., Kim M.S. Ondamtanggamibang protects neurons from oxidative stress with induction of heme oxygenase-1. J Ethnopharmacol 2006, 108:294-298.
26. Lemaure B., Touché A., Zbinden I., Moulin J., Courtois D., Macé K., et al. Administration of Cyperus rotundus tubers extract prevents weight gain in obese Zucker rats. Phytother Res 2007, 21:724-730.
27. Lin Y.C., Huang Y.C., Chen S.C., Liaw C.C., Kuo S.C., Huang L.J., et al. Neuroprotective effects of ugonin K on hydrogen peroxide-induced cell death in human neuroblastoma SH-SY5Y cells. Neurochem Res 2009, 34:923-930.
28. Maruyama W., Takahashi T., Youdim M., Naoi M. The anti-Parkinson drug, rasagiline, prevents apoptotic DNA damage induced by peroxynitrite in human dopaminergic neuroblastoma SH-SY5Y cells. J Neural Transm 2002, 109:467-481.
29. Ohkawa H., Ohishi N., Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979, 95:351-358.
30. Pal S., He K., Aizenman E. Nitrosative stress and potassium channel-mediated neuronal apoptosis: is zinc the link?. Pflugers Arch 2004, 448:296-303.
31. Paula F.B., Gouvêa C.M., Alfredo P.P., Salgado I. Protective action of a hexane crude extract of Pterodon emarginatus fruits against oxidative and nitrosative stress induced by acute exercise in rats. BMC Complement Altern Med 2005, 17:17.
32. Prehn J.H., Bindokas V.P., Jordán J., Galindo M.F., Ghadge G.D., Roos R.P., et al. Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons. Mol Pharmacol 1996, 49:319-328.
33. Savitha S., Panneerselvam C. Mitochondrial membrane damage during aging process in rat heart: potential efficacy of L-carnitine and DL alpha lipoic acid. Mech Ageing Dev 2006, 127:349-355.
34. Seo W.G., Pae H.O., Oh G.S., Chai K.Y., Kwon T.O., Yun Y.G., et al. Inhibitory effects of methanol extract of Cyperus rotundus rhizomes on nitric oxide and superoxide productions by murine macrophage cell line, RAW 264. 7 cells. J Ethnopharmacol 2001, 76:59-64.
35. Sharma R., Gupta R. Cyperus rotundus extract inhibits acetylcholinesterase activity from animal and plants as well as inhibits germination and seedling growth in wheat and tomato. Life Sci 2007, 80:2389-2392.
36. Sharma S.K., Ebadi M. Metallothionein attenuates 3-morpholinosydnonimine (SIN-1)-induced oxidative stress in dopaminergic neurons. Antioxid Redox Signal 2003, 5:251-264.
37. Singh N.P., McCoy M.T., Tice R.R., Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 1988, 175:184-191.
38. Sonwa M.M., König W.A. Chemical study of the essential oil of Cyperus rotundus. Phytochemistry 2001, 58:799-810.
39. Stewart V.C., Heales S.J. Nitric oxide-induced mitochondrial dysfunction: implications for neurodegeneration. Free Radic Biol Med 2000, 334:287-303.
40. Su J.H., Deng G., Cotman C.W., Neuronal DNA damage precedes tangle formation and is associated with up-regulation of nitrotyrosine in Alzheimer's disease brain. Brain Res 1997, 774:193-199.
41. Sunil A.G., Kesavanarayanan K.S., Kalaivani P., Sathiya S., Ranju V., Priya R.J., et al. Total oligomeric flavonoids of Cyperus rotundus ameliorates neurological deficits, excitotoxicity and behavioral alterations induced by cerebral ischemic-reperfusion injury in rats. Brain Res Bull 2011, 84:394-405.
42. Szabó C., Ischiropoulos H., Radi R. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat Rev Drug Discov 2007, 6:662-680.
43. Torreilles F., Salman-Tabcheh S., Guérin M., Torreilles J. Neurodegenerative disorders: the role of peroxynitrite. Brain Res Brain Res Rev 1999, 30:153-163.
44. Tsoyi K., Jang H.J., Lee Y.S., Kim Y.M., Kim H.J., Seo H.G., et al. (+)-Nootkatone and (+)-valencene from rhizomes of Cyperus rotundus increase survival rates in septic mice due to heme oxygenase-1 induction. J Ethnopharmacol 2011, 137:1311-1317.
45. Ubl J.J., Chatton J.Y., Chen S., Stucki J.W. A critical evaluation of in situ measurement of mitochondrial electrical potentials in single hepatocytes. Biochim Biophys Acta 1996, 1276:124-132.
46. Uddin S.J., Mondal K., Shilpi J.A., Rahman M.T. Antidiarrhoeal activity of Cyperus rotundus. Fitoterapia 2006, 77:134-136.
47. Umeric S.C., Ezeuzo H.O. Physicochemical characterization and utilization of Cyperus rotundus starch. Bioresour Technol 2000, 72:193-196.
48. Wang Y.J., Ho Y.S., Pan M.H., Lin J.K., Wang Y.J., Ho Y.S., et al. Mechanisms of cell death induced by nitric oxide and peroxynitrite in Calu-1 cells. Environ Toxicol Pharmacol 1998, 6:35-44.
49. Xie Z., Wei M., Morgan T.E., Fabrizio P., Han D., Finch C.E., et al. Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia. J Neurosci 2002, 22:3484-3492.
50. Zhu M., Luk H.H., Fung H.S., Luk C.T. Cytoprotective effects of Cyperus rotundus against ethanol induced gastric ulceration in rats. Phytother Res 1998, 11:392-394.