-
1
-
-
0037321379
-
Oxidative stress in neurodegenerative diseases: Therapeutic implications for superoxide dismutase mimetics
-
DOI 10.1517/14712598.3.1.127
-
K Pong 2003 Oxidative stress in neurodegenerative diseases: therapeutic implications for superoxide dismutase mimetics Expert Opin Biol Ther 3 127 139 10.1517/14712598.3.1.127 12718737 (Pubitemid 36193657)
-
(2003)
Expert Opinion on Biological Therapy
, vol.3
, Issue.1
, pp. 127-139
-
-
Pong, K.1
-
3
-
-
0037366104
-
Oxidative stress, cell cycle, and neurodegeneration
-
12639981
-
JA Klein SL Ackerman 2003 Oxidative stress, cell cycle, and neurodegeneration J Clin Invest 111 785 793 12639981
-
(2003)
J Clin Invest
, vol.111
, pp. 785-793
-
-
Klein, J.A.1
Ackerman, S.L.2
-
4
-
-
68149156531
-
Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: How neurons are lost in the Bermuda triangle
-
10.1186/1750-1326-4-24 19500376
-
KA Malkus E Tsika H Ischiropoulos 2009 Oxidative modifications, mitochondrial dysfunction, and impaired protein degradation in Parkinson's disease: how neurons are lost in the Bermuda triangle Mol Neurodegener 4 24 10.1186/1750-1326-4-24 19500376
-
(2009)
Mol Neurodegener
, vol.4
, pp. 24
-
-
Malkus, K.A.1
Tsika, E.2
Ischiropoulos, H.3
-
5
-
-
0037237927
-
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
-
12531868
-
H Ischiropoulos JS Beckman 2003 Oxidative stress and nitration in neurodegeneration: cause, effect, or association? J Clin Invest 111 163 169 12531868
-
(2003)
J Clin Invest
, vol.111
, pp. 163-169
-
-
Ischiropoulos, H.1
Beckman, J.S.2
-
6
-
-
34248187134
-
Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders
-
DOI 10.2741/2130
-
C Mancuso G Scapagini D Curro AM Giuffrida Stella C De Marco DA Butterfield V Calabrese 2007 Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders Front Biosci 12 1107 1123 10.2741/2130 17127365 (Pubitemid 46846882)
-
(2007)
Frontiers in Bioscience
, vol.12
, Issue.3
, pp. 1107-1123
-
-
Mancuso, C.1
Scapagnini, G.2
Curro, D.3
Giuffrida Stella, A.M.4
De Marco, C.5
Butterfield, D.A.6
Calabrese, V.7
-
7
-
-
0029805172
-
Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
-
8944624
-
JS Beckman WH Koppenol 1996 Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly Am J Physiol 271 C1424 C1437 8944624
-
(1996)
Am J Physiol
, vol.271
-
-
Beckman, J.S.1
Koppenol, W.H.2
-
8
-
-
0029146273
-
Peroxynitrite-induced cytotoxicity in PC12 cells: Evidence for an apoptotic mechanism differentially modulated by neurotrophic factors
-
7561848
-
AG Estevez R Radi L Barbeito JT Shin JA Thompson JS Beckman 1995 Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors J Neurochem 65 1543 1550 7561848
-
(1995)
J Neurochem
, vol.65
, pp. 1543-1550
-
-
Estevez, A.G.1
Radi, R.2
Barbeito, L.3
Shin, J.T.4
Thompson, J.A.5
Beckman, J.S.6
-
9
-
-
0036169830
-
Selective nitration of mitochondrial complex I by peroxynitrite: Involvement in mitochondria dysfunction and cell death of dopaminergic SH-SY5Y cells
-
DOI 10.1007/s702-002-8232-1
-
T Yamamoto W Maruyama Y Kato H Yi M Shamoto-Nagai M Tanaka Y Sato M Naoi 2002 Selective nitration of mitochondrial complex I by peroxynitrite: involvement in mitochondria dysfunction and cell death of dopaminergic SH-SY5Y cells J Neural Transm 109 1 13 10.1007/s702-002-8232-1 11793158 (Pubitemid 34146585)
-
(2002)
Journal of Neural Transmission
, vol.109
, Issue.1
, pp. 1-13
-
-
Yamamoto, T.1
Maruyama, W.2
Kato, Y.3
Yi, H.4
Shamoto-Nagai, M.5
Tanaka, M.6
Sato, Y.7
Naoi, M.8
-
10
-
-
0036338635
-
ARF pathway
-
DOI 10.1006/niox.2001.0389
-
T Kaji I Kaieda T Hisatsune S Kaminogawa 2002 3-Morpholinosydnonimine hydrochloride induces p53-dependent apoptosis in murine primary neural cells: a critical role for p21(ras)-MAPK-p19(ARF) pathway Nitric Oxide 6 125 134 10.1006/niox.2001.0389 11890736 (Pubitemid 34848434)
-
(2002)
Nitric Oxide - Biology and Chemistry
, vol.6
, Issue.2
, pp. 125-134
-
-
Kaji, T.1
Kaieda, I.2
Hisatsune, T.3
Kaminogawa, S.4
-
11
-
-
0037432615
-
Multiple pathways of peroxynitrite cytotoxicity
-
DOI 10.1016/S0378-4274(02)00507-6
-
C Szabo 2003 Multiple pathways of peroxynitrite cytotoxicity Toxicol Lett 140-141 105 112 10.1016/S0378-4274(02)00507-6 12676456 (Pubitemid 36378928)
-
(2003)
Toxicology Letters
, vol.140-141
, pp. 105-112
-
-
Szabo, C.1
-
12
-
-
18044388712
-
Poly (ADP-Ribose) polymerase inhibitors as potential therapeutic agents in stroke and neurotrauma
-
DOI 10.2174/1568007053544138
-
K Komjati VC Besson C Szabo 2005 Poly (adp-ribose) polymerase inhibitors as potential therapeutic agents in stroke and neurotrauma Curr Drug Targets CNS Neurol Disord 4 179 194 10.2174/1568007053544138 15857303 (Pubitemid 40601609)
-
(2005)
Current Drug Targets: CNS and Neurological Disorders
, vol.4
, Issue.2
, pp. 179-194
-
-
Komjati, K.1
Besson, V.C.2
Szabo, C.3
-
13
-
-
0034671886
-
Metallothionein inhibits peroxynitrite-induced DNA and lipoprotein damage
-
DOI 10.1074/jbc.C000593200
-
L Cai JB Klein YJ Kang 2000 Metallothionein inhibits peroxynitrite- induced DNA and lipoprotein damage J Biol Chem 275 38957 38960 10.1074/jbc.C000593200 11042194 (Pubitemid 32058905)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.50
, pp. 38957-38960
-
-
Cai, L.1
Klein, J.B.2
Kang, Y.J.3
-
14
-
-
18244415707
-
Defenses against peroxynitrite: Selenocompounds and flavonoids
-
DOI 10.1016/S0378-4274(02)00511-8
-
LO Klotz H Sies 2003 Defenses against peroxynitrite: selenocompounds and flavonoids Toxicol Lett 140-141 125 132 10.1016/S0378-4274(02)00511-8 12676458 (Pubitemid 36378930)
-
(2003)
Toxicology Letters
, vol.140-141
, pp. 125-132
-
-
Klotz, L.-O.1
Sies, H.2
-
15
-
-
0032738998
-
Antioxidative properties of pyruvate and protection of the ischemic rat heart during cardioplegia
-
DOI 10.1097/00005344-199911000-00005
-
P Dobsak C Courderot-Masuyer M Zeller C Vergely A Laubriet M Assem JC Eicher JR Teyssier JE Wolf L Rochette 1999 Antioxidative properties of pyruvate and protection of the ischemic rat heart during cardioplegia J Cardiovasc Pharmacol 34 651 659 10.1097/00005344-199911000-00005 10547080 (Pubitemid 29491726)
-
(1999)
Journal of Cardiovascular Pharmacology
, vol.34
, Issue.5
, pp. 651-659
-
-
Dobsak, P.1
Courderot-Masuyer, C.2
Zeller, M.3
Vergely, C.4
Laubriet, A.5
Assem, M.6
Eicher, J.-C.7
Teyssier, J.-R.8
Wolf, J.-E.9
Rochette, L.10
-
16
-
-
0000728273
-
Pyruvate-C14, Purity and Stability
-
10.1016/0003-2697(64)90043-0 14186671
-
RW Vonkorff 1964 Pyruvate-C14, Purity and Stability Anal Biochem 8 171 178 10.1016/0003-2697(64)90043-0 14186671
-
(1964)
Anal Biochem
, vol.8
, pp. 171-178
-
-
Vonkorff, R.W.1
-
17
-
-
0034883436
-
Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats
-
10.1097/00003246-200108000-00003 11505117
-
CA Sims S Wattanasirichaigoon MJ Menconi AM Ajami MP Fink 2001 Ringer's ethyl pyruvate solution ameliorates ischemia/reperfusion-induced intestinal mucosal injury in rats Crit Care Med 29 1513 1518 10.1097/00003246-200108000- 00003 11505117
-
(2001)
Crit Care Med
, vol.29
, pp. 1513-1518
-
-
Sims, C.A.1
Wattanasirichaigoon, S.2
Menconi, M.J.3
Ajami, A.M.4
Fink, M.P.5
-
18
-
-
26944449700
-
Anti-inflammatory mechanism is involved in ethyl pyruvate-mediated efficacious neuroprotection in the postischemic brain
-
DOI 10.1016/j.brainres.2005.08.029, PII S0006899305012047
-
JB Kim YM Yu SW Kim JK Lee 2005 Anti-inflammatory mechanism is involved in ethyl pyruvate-mediated efficacious neuroprotection in the postischemic brain Brain Res 1060 188 192 10.1016/j.brainres.2005.08.029 16226231 (Pubitemid 41483605)
-
(2005)
Brain Research
, vol.1060
, Issue.1-2
, pp. 188-192
-
-
Kim, J.-B.1
Yu, Y.-M.2
Kim, S.-W.3
Lee, J.-K.4
-
20
-
-
26444558061
-
Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window
-
DOI 10.1161/01.STR.0000181779.83472.35
-
YM Yu JB Kim KW Lee SY Kim PL Han JK Lee 2005 Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window Stroke 36 2238 2243 10.1161/01.STR.0000181779.83472.35 16141417 (Pubitemid 41429253)
-
(2005)
Stroke
, vol.36
, Issue.10
, pp. 2238-2243
-
-
Yu, Y.-M.1
Kim, J.-B.2
Lee, K.-W.3
Kim, S.Y.4
Han, P.-L.5
Lee, J.-K.6
-
21
-
-
62349126169
-
Neuroprotective effects of ethyl pyruvate on brain energy metabolism after ischemia-reperfusion injury: A 31P-nuclear magnetic resonance study
-
10.1007/s11064-008-9871-x 18985448
-
O Tokumaru C Kuroki N Yoshimura T Sakamoto H Takei K Ogata T Kitano N Nisimaru I Yokoi 2009 Neuroprotective effects of ethyl pyruvate on brain energy metabolism after ischemia-reperfusion injury: a 31P-nuclear magnetic resonance study Neurochem Res 34 775 785 10.1007/s11064-008-9871-x 18985448
-
(2009)
Neurochem Res
, vol.34
, pp. 775-785
-
-
Tokumaru, O.1
Kuroki, C.2
Yoshimura, N.3
Sakamoto, T.4
Takei, H.5
Ogata, K.6
Kitano, T.7
Nisimaru, N.8
Yokoi, I.9
-
23
-
-
0036298874
-
Aspirin potently inhibits oxidative DNA strand breaks: Implications for cancer chemoprevention
-
DOI 10.1016/S0006-291X(02)00271-1, PII S0006291X02002711
-
CS Hsu Y Li 2002 Aspirin potently inhibits oxidative DNA strand breaks: implications for cancer chemoprevention Biochem Biophys Res Commun 293 705 709 10.1016/S0006-291X(02)00271-1 12054526 (Pubitemid 34687244)
-
(2002)
Biochemical and Biophysical Research Communications
, vol.293
, Issue.2
, pp. 705-709
-
-
Susan Hsu, C.1
Li, Y.2
-
24
-
-
59949089422
-
Alpha-lipoic acid potently inhibits peroxynitrite-mediated DNA strand breakage and hydroxyl radical formation: Implications for the neuroprotective effects of alpha-lipoic acid
-
10.1007/s11010-008-9971-6 19082545
-
Z Jia H Zhu MJ Vitto BR Misra Y Li HP Misra 2009 Alpha-lipoic acid potently inhibits peroxynitrite-mediated DNA strand breakage and hydroxyl radical formation: implications for the neuroprotective effects of alpha-lipoic acid Mol Cell Biochem 323 131 138 10.1007/s11010-008-9971-6 19082545
-
(2009)
Mol Cell Biochem
, vol.323
, pp. 131-138
-
-
Jia, Z.1
Zhu, H.2
Vitto, M.J.3
Misra, B.R.4
Li, Y.5
Misra, H.P.6
-
25
-
-
44449129847
-
EPR studies on the superoxide-scavenging capacity of the nutraceutical resveratrol
-
10.1007/s11010-008-9756-y 18409032
-
Z Jia H Zhu BR Misra JE Mahaney Y Li HP Misra 2008 EPR studies on the superoxide-scavenging capacity of the nutraceutical resveratrol Mol Cell Biochem 313 187 194 10.1007/s11010-008-9756-y 18409032
-
(2008)
Mol Cell Biochem
, vol.313
, pp. 187-194
-
-
Jia, Z.1
Zhu, H.2
Misra, B.R.3
Mahaney, J.E.4
Li, Y.5
Misra, H.P.6
-
26
-
-
0029046840
-
Detection by ESR of DMPO hydroxyl adduct formation from islets of langerhans
-
10.1016/0891-5849(95)00018-S 7649493
-
GM Pieper CC Felix B Kalyanaraman M Turk AM Roza 1995 Detection by ESR of DMPO hydroxyl adduct formation from islets of langerhans Free Radic Biol Med 19 219 225 10.1016/0891-5849(95)00018-S 7649493
-
(1995)
Free Radic Biol Med
, vol.19
, pp. 219-225
-
-
Pieper, G.M.1
Felix, C.C.2
Kalyanaraman, B.3
Turk, M.4
Roza, A.M.5
-
27
-
-
0027296545
-
DNA damage resulting from the oxidation of hydroquinone by copper: Role for a Cu(II)/Cu(I) redox cycle and reactive oxygen generation
-
10.1093/carcin/14.7.1303 8392444
-
Y Li MA Trush 1993 DNA damage resulting from the oxidation of hydroquinone by copper: role for a Cu(II)/Cu(I) redox cycle and reactive oxygen generation Carcinogenesis 14 1303 1311 10.1093/carcin/14.7.1303 8392444
-
(1993)
Carcinogenesis
, vol.14
, pp. 1303-1311
-
-
Li, Y.1
Trush, M.A.2
-
28
-
-
0036268226
-
Possible roles of nitric oxide in the physiology and pathophysiology of the mammalian cochlea
-
10.1111/j.1749-6632.2002.tb04073.x 12076980
-
RS Ruan 2002 Possible roles of nitric oxide in the physiology and pathophysiology of the mammalian cochlea Ann N Y Acad Sci 962 260 274 10.1111/j.1749-6632.2002.tb04073.x 12076980
-
(2002)
Ann N y Acad Sci
, vol.962
, pp. 260-274
-
-
Ruan, R.S.1
-
29
-
-
0242348817
-
Cyclic AMP and Cyclic GMP Independent Stimulation of Ventricular Calcium Current by Peroxynitrite Donors in Guinea Pig Myocytes
-
DOI 10.1002/jcp.10368
-
D Malan RC Levi G Alloatti A Marcantoni I Bedendi MP Gallo 2003 Cyclic AMP and cyclic GMP independent stimulation of ventricular calcium current by peroxynitrite donors in guinea pig myocytes J Cell Physiol 197 284 296 10.1002/jcp.10368 14502568 (Pubitemid 37485257)
-
(2003)
Journal of Cellular Physiology
, vol.197
, Issue.2
, pp. 284-296
-
-
Malan, D.1
Levi, R.C.2
Alloatti, G.3
Marcantoni, A.4
Bedendi, I.5
Gallo, M.P.6
-
31
-
-
1842736342
-
Potent inhibition of peroxynitrite-induced DNA strand breakage by ethanol: Possible implications for ethanol-mediated cardiovascular protection
-
DOI 10.1016/j.phrs.2003.12.010, PII S1043661803004183
-
Z Cao Y Li 2004 Potent inhibition of peroxynitrite-induced DNA strand breakage by ethanol: possible implications for ethanol-mediated cardiovascular protection Pharmacol Res 50 13 19 10.1016/j.phrs.2003.12.010 15082025 (Pubitemid 38479664)
-
(2004)
Pharmacological Research
, vol.50
, Issue.1
, pp. 13-19
-
-
Cao, Z.1
Li, Y.2
-
32
-
-
0030013889
-
Selenium-containing compounds protect DNA from single-strand breaks caused by peroxynitrite
-
DOI 10.1006/abbi.1996.0245
-
I Roussyn K Briviba H Masumoto H Sies 1996 Selenium-containing compounds protect DNA from single-strand breaks caused by peroxynitrite Arch Biochem Biophys 330 216 218 10.1006/abbi.1996.0245 8651699 (Pubitemid 26166644)
-
(1996)
Archives of Biochemistry and Biophysics
, vol.330
, Issue.1
, pp. 216-218
-
-
Roussyn, I.1
Briviba, K.2
Masumoto, H.3
Sies, H.4
-
33
-
-
34547673497
-
Peroxynitrite: Biochemistry, pathophysiology and development of therapeutics
-
DOI 10.1038/nrd2222, PII NRD2222
-
C Szabo H Ischiropoulos R Radi 2007 Peroxynitrite: biochemistry, pathophysiology and development of therapeutics Nat Rev Drug Discov 6 662 680 10.1038/nrd2222 17667957 (Pubitemid 47207751)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.8
, pp. 662-680
-
-
Szabo, C.1
Ischiropoulos, H.2
Radi, R.3
-
34
-
-
0029013876
-
5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide: A new efficient phosphorylated nitrone for the in vitro and in vivo spin trapping of oxygen-centered radicals
-
10.1021/jm00002a007 7830268
-
C Frejaville H Karoui B Tuccio F Le Moigne M Culcasi S Pietri R Lauricella P Tordo 1995 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide: a new efficient phosphorylated nitrone for the in vitro and in vivo spin trapping of oxygen-centered radicals J Med Chem 38 258 265 10.1021/jm00002a007 7830268
-
(1995)
J Med Chem
, vol.38
, pp. 258-265
-
-
Frejaville, C.1
Karoui, H.2
Tuccio, B.3
Le Moigne, F.4
Culcasi, M.5
Pietri, S.6
Lauricella, R.7
Tordo, P.8
-
35
-
-
0023505008
-
Spin trapping: ESR parameters of spin adducts
-
10.1016/S0891-5849(87)80033-3 2826304
-
GR Buettner 1987 Spin trapping: ESR parameters of spin adducts Free Radic Biol Med 3 259 303 10.1016/S0891-5849(87)80033-3 2826304
-
(1987)
Free Radic Biol Med
, vol.3
, pp. 259-303
-
-
Buettner, G.R.1
-
36
-
-
0029114341
-
Spin trap studies on the decomposition of peroxynitrite
-
10.1006/abbi.1995.1364 7639532
-
JN Lemercier GL Squadrito WA Pryor 1995 Spin trap studies on the decomposition of peroxynitrite Arch Biochem Biophys 321 31 39 10.1006/abbi.1995.1364 7639532
-
(1995)
Arch Biochem Biophys
, vol.321
, pp. 31-39
-
-
Lemercier, J.N.1
Squadrito, G.L.2
Pryor, W.A.3
-
37
-
-
0027057113
-
EPR kinetic studies of superoxide radicals generated during the autoxidation of 1-methyl-4-phenyl-2, 3-dihydropyridinium, a bioactivated intermediate of parkinsonian-inducing neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine
-
1331093
-
LY Zang HP Misra 1992 EPR kinetic studies of superoxide radicals generated during the autoxidation of 1-methyl-4-phenyl-2, 3-dihydropyridinium, a bioactivated intermediate of parkinsonian-inducing neurotoxin 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine J Biol Chem 267 23601 23608 1331093
-
(1992)
J Biol Chem
, vol.267
, pp. 23601-23608
-
-
Zang, L.Y.1
Misra, H.P.2
-
38
-
-
0032753172
-
Effects of mannitol or catalase on the generation of reactive oxygen species leading to DNA damage by chromium(VI) reduction with ascorbate
-
DOI 10.1021/tx9802264
-
TC Tsou HJ Lai JL Yang 1999 Effects of mannitol or catalase on the generation of reactive oxygen species leading to DNA damage by Chromium(VI) reduction with ascorbate Chem Res Toxicol 12 1002 1009 10.1021/tx9802264 10525278 (Pubitemid 29498376)
-
(1999)
Chemical Research in Toxicology
, vol.12
, Issue.10
, pp. 1002-1009
-
-
Tsou, T.-C.1
Lai, H.-J.2
Yang, J.-L.3
-
39
-
-
43249094826
-
Ethyl pyruvate
-
10.1097/ACO.0b013e3282f63c2e 18443482
-
MP Fink 2008 Ethyl pyruvate Curr Opin Anaesthesiol 21 160 167 10.1097/ACO.0b013e3282f63c2e 18443482
-
(2008)
Curr Opin Anaesthesiol
, vol.21
, pp. 160-167
-
-
Fink, M.P.1
-
40
-
-
0033179481
-
Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes
-
DOI 10.1046/j.1432-1327.1999.00534.x
-
EK Ainscow MD Brand 1999 Top-down control analysis of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes Eur J Biochem 263 671 685 10.1046/j.1432-1327.1999.00534.x 10469130 (Pubitemid 29361939)
-
(1999)
European Journal of Biochemistry
, vol.263
, Issue.3
, pp. 671-685
-
-
Ainscow, E.K.1
Brand, M.D.2
-
41
-
-
0033021002
-
Neuroinflammatory processes are important in neurodegenerative diseases: An hypothesis to explain the increased formation of reactive oxygen and nitrogen species as major factors involved in neurodegenerative disease development
-
DOI 10.1016/S0891-5849(98)00293-7, PII S0891584998002937
-
RA Floyd 1999 Neuroinflammatory processes are important in neurodegenerative diseases: an hypothesis to explain the increased formation of reactive oxygen and nitrogen species as major factors involved in neurodegenerative disease development Free Radic Biol Med 26 1346 1355 10.1016/S0891-5849(98)00293-7 10381209 (Pubitemid 29262724)
-
(1999)
Free Radical Biology and Medicine
, vol.26
, Issue.9-10
, pp. 1346-1355
-
-
Floyd, R.A.1
|