(+)-Nootkatone and (+)-valencene from rhizomes of Cyperus rotundus increase survival rates in septic mice due to heme oxygenase-1 induction

Journal of Ethnopharmacology

Volumn 137, Issue 3, 2011, Pages 1311-1317

  Tsoyi, Konstantin ^a   Jang, Hwa Jin ^a   Lee, Young Soo ^a   Kim, Young Min ^a   Kim, Hye Jung ^a   Seo, Han Geuk ^a   Lee, Jae Heun ^a   Kwak, Jong Hwan ^b   Lee, Dong Ung ^c   Chang, Ki Churl ^a,d  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Sungkyunkwan University   (South Korea)

^c Dongguk University   (South Korea)

^d Gyeongsang National University   (South Korea)

Author keywords

Heme oxygenase 1; Inflammation; iNOS; Nootkatone; Sepsis; Valencene

Indexed keywords

CYPERUS ROTUNDUS EXTRACT; HEME OXYGENASE 1; HIGH MOBILITY GROUP B1 PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NOOTKATONE; SESQUITERPENE DERIVATIVE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VALENCENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; GENETIC TRANSFECTION; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RHIZOME; SEPSIS; SURVIVAL RATE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CYPERUS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HEME OXYGENASE-1; HMGB1 PROTEIN; MACROPHAGES; MEMBRANE PROTEINS; MICE; MICE, INBRED ICR; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; PLANTS, MEDICINAL; RHIZOME; RNA INTERFERENCE; SEPSIS; SESQUITERPENES; TIME FACTORS; TRANSFECTION; UP-REGULATION;

ANIMALIA; CYPERUS ROTUNDUS; MUS;

EID: 84860392727     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.07.062     Document Type: Article

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