N-Cadherin- and L1-functionalised conducting polymers for synergistic stimulation and guidance of neural cell growth

Biomaterials

Volumn 34, Issue 14, 2013, Pages 3603-3617

  Collazos Castro, Jorge E ^a   Hernández Labrado, Gabriel R ^b   Polo, José L ^b   García Rama, Concepción ^a  

^a HOSPITAL NACIONAL DE PARAPLÉJICOS   (Spain)

^b UNIVERSITY OF CASTILLA LA MANCHA   (Spain)

Author keywords

Conducting polymers; L1; Microfibre; N Cadherin; Neural; PEDOT

Indexed keywords

L1; MICROFIBRE; N-CADHERIN; NEURAL; PEDOT;

CARBON; CHRONOAMPEROMETRY; CYCLIC VOLTAMMETRY; ELECTRIC PROPERTIES; ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY; GLYCOPROTEINS; NEURONS; RECOMBINANT PROTEINS; REPAIR; SCAFFOLDS (BIOLOGY); SURFACES;

CONDUCTING POLYMERS;

CARBON; CONDUCTING POLYMER; NERVE CELL ADHESION MOLECULE; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; CELL MIGRATION; CHEMICAL ANALYSIS; CONTROLLED STUDY; COVALENT BOND; DENDRITIC CELL; IMMUNOHISTOCHEMISTRY; MICROSCOPY; NERVE CELL GROWTH; POLYMERIZATION; POTENTIOMETRY; PRIORITY JOURNAL;

ANIMALS; CADHERINS; CELLS, CULTURED; NEURONS; POLYMERS; RATS;

EID: 84875260113     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.01.097     Document Type: Article

References (58)

1. Guangchun L., Pickup P.G. Ion transport in poly(3,4-ethylenedioxythiophene)-poly(styrene-4-sulfonate) composites. Phys Chem Chem Phys 2000, 2:1255-1260.
2. Wang X., Shapiro B., Smela E. Visualizing ion currents in conjugated polymers. Adv Mater 2004, 16:1605-1609.
3. Hernandez-Labrado G.R., Contreras-Donayre R.E., Collazos-Castro J.E., Polo J.L. Subdiffusion behavior in poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) evidenced by electrochemical impedance spectroscopy. J Electroanal Chem 2011, 659:201-204.
4. Cui X., Martin D.C. Electrochemical deposition and characterization of poly(3,4-ethylenedioxythiophene) on neural microelectrode arrays. Sensors Actuators B 2003, 89:92-102.
5. Llinás R.R., Walton K.D., Nakao M., Hunter I., Anquetil P.A. Neuro-vascular central nervous recording/stimulating system: using nanotechnology probes. J Nanoparticle Res 2005, 7:111-127.
6. Simon D.T., Kurup S., Larsson K.C., Hori R., Tybrandt K., Goiny M., et al. Organic electronics for precise delivery of neurotransmitters to modulate mammalian sensory function. Nat Mater 2009, 8:742-746.
7. Collazos-Castro J.E., Polo J.L., Hernández-Labrado G., Padial-Cañete V., García-Rama C. Bioelectrochemical control of neural cell development on conducting polymers. Biomaterials 2010, 31:9244-9255.
8. Lu Y., Li Y., Pan J., Wei P., Liu N., Wu B., et al. Poly(3,4-ethylenedioxythiophene)/poly(styrenesulfonate)-poly(vinyl alcohol)/poly(acrylic acid) interpenetrating polymer networks for improving optrode-neural tissue interface in optogenetics. Biomaterials 2012, 33:378-394.
9. Green R.A., Hassarati R.T., Bouchinet L., Lee C.S., Cheong G.L., Yu J.F., et al. Substrate dependent stability of conducting polymer coatings on medical electrodes. Biomaterials 2012, 33:5875-5886.
10. Chikar J.A., Hendricks J.L., Richardson-Burns S.M., Raphael Y., Pfingst B.E., Martin D.C. The use of a dual PEDOT and RGD-functionalized alginate hydrogel coating to provide sustained drug delivery and improved cochlear implant function. Biomaterials 2012, 33:1982-1990.
11. Ludwig K.A., Uram J.D., Yang J., Martin D.C., Kipke D.R. Chronic neural recordings using silicon microelectrode arrays electrochemically deposited with a poly(3,4-ethylenedioxythiophene) (PEDOT) film. J Neural Eng 2006, 3:59-70.
12. Nyberg T., Shimada A., Torimitsu K. Ion conducting polymer microelectrodes for interfacing with neural networks. J Neurosci Methods 2007, 160:16-25.
13. Collazos-Castro J.E., Muñetón-Gómez V., Nieto-Sampedro M. Olfactory glia transplantation into cervical spinal cord contusion injuries. J Neurosurg Spine 2005, 3:308-317.
14. Richardson R.T., Thompson B., Moulton S., Newbold C., Lum M.G., Cameron A., et al. The effect of polypyrrole with incorporated neurotrophin-3 on the promotion of neurite outgrowth from auditory neurons. Biomaterials 2007, 28:513-523.
15. Thompson B.C., Richardson R.T., Moulton S.E., Evans A.J., O'Leary S., Clark G.M., et al. Conducting polymers, dual neurotrophins and pulsed electrical stimulation - dramatic effects on neurite outgrowth. J Control Release 2010, 141:161-167.
16. Hsiao Y.S., Lin C.C., Hsieh H.J., Tsai S.M., Kuo C.W., Chu C.W., et al. Manipulating location, polarity, and outgrowth length of neuron-like pheochromocytoma (PC-12) cells on patterned organic electrode arrays. Lab Chip 2011, 11:3674-3680.
17. Goldberg J.L. How does an axon grow?. Genes Dev 2003, 17:941-958.
18. Carmel J.B., Berrol L.J., Brus-Ramer M., Martin J.H. Chronic electrical stimulation of the intact corticospinal system after unilateral injury restores skilled locomotor control and promotes spinal axon outgrowth. J Neurosci 2010, 30:10918-10926.
19. Ishibashi T., Dakin K.A., Stevens B., Lee P.R., Kozlov S.V., Stewart C.L., et al. Astrocytes promote myelination in response to electrical impulses. Neuron 2006, 49:823-832.
20. Yamato H., Ohwa M., Wernet W. Stability of polypyrrole and poly(3,4-ethylenedioxythiophene) for biosensor application. J Electroanal Chem 1995, 397:163-170.
21. Song H.K., Toste B., Ahmann K., Hoffman-Kim D., Palmore G.T. Micropatterns of positive guidance cues anchored to polypyrrole doped with polyglutamic acid: a new platform for characterizing neurite extension in complex environments. Biomaterials 2006, 27:473-484.
22. Liu X., Yue Z., Higgins M.J., Wallace G.G. Conducting polymers with immobilised fibrillar collagen for enhanced neural interfacing. Biomaterials 2011, 32:7309-7317.
23. Fischer G., Kunemund V., Schachner M. Neurite outgrowth patterns in cerebellar microexplant cultures are affected by antibodies to the cell surface glycoprotein L1. J Neurosci 1986, 6:605-612.
24. Lagenaur C., Lemmon V. An L1-like molecule, the 8D9 antigen, is a potent substrate for neurite extension. Proc Natl Acad Sci U S A 1987, 84:7753-7757.
25. Webb K., Budko E., Neuberger T.J., Chen S., Schachner M., Tresco P.A. Substrate-bound human recombinant L1 selectively promotes neuronal attachment and outgrowth in the presence of astrocytes and fibroblasts. Biomaterials 2001, 22:1017-1028.
26. Azemi E., Lagenaur C.F., Cui X.T. The surface immobilization of the neural adhesion molecule L1 on neural probes and its effect on neuronal density and gliosis at the probe/tissue interface. Biomaterials 2011, 32:681-692.
27. Esch T., Lemmon V., Banker G. Differential effects of NgCAM and N-cadherin on the development of axons and dendrites by cultured hippocampal neurons. J Neurocytol 2000, 29:215-223.
28. Shi P., Shen K., Kam L.C. Local presentation of L1 and N-cadherin in multicomponent, microscale patterns differentially direct neuron function in vitro. Dev Neurobiol 2007, 67:1765-1776.
29. Bixby J.L., Zhang R. Purified N-cadherin is a potent substrate for the rapid induction of neurite outgrowth. J Cell Biol 1990, 110:1253-1260.
30. Matsunaga M., Hatta K., Nagafuchi A., Takeichi M. Guidance of optic nerve fibres by N-cadherin adhesion molecules. Nature 1988, 334:62-64.
31. Treubert-Zimmermann U., Heyers D., Redies C. Targeting axons to specific fiber tracts in vivo by altering cadherin expression. J Neurosci 2002, 22:7617-7626.
32. Jossin Y., Cooper J.A. Reelin, Rap1 and N-cadherin orient the migration of multipolar neurons in the developing neocortex. Nat Neurosci 2011, 14:697-703.
33. Tang L., Hung C.P., Schuman E.M. A role for the cadherin family of cell adhesion molecules in hippocampal long-term potentiation. Neuron 1998, 20:1165-1175.
34. Okamura K., Tanaka H., Yagita Y., Saeki Y., Taguchi A., Hiraoka Y., et al. Cadherin activity is required for activity-induced spine remodeling. J Cell Biol 2004, 167:961-972.
35. 2 anatase nanostructured surfaces. Thin Solid Films 2009, 518:160-170.
36. Dotti C.G., Sullivan C.A., Banker G.A. The establishment of polarity by hippocampal neurons in culture. J Neurosci 1988, 8:1454-1468.
37. Kvarnström C., Neugebauer H., Blomquist S., Ahonen H.J., Kankare J., Ivaska A. In situ spectrochemical characterization of poly(3,4-ethylenedioxythiophene). Electrochim Acta 1999, 44:2739-2750.
38. Randriamahazaka H., Plesse C., Teyssié D., Chevrot C. Electrochemical behaviour of poly(3,4-ethylenedioxythiophene) in a room-temperature ionic liquid. Electrochem Commun 2003, 5:613-617.
39. Tang F., Dent E.W., Kalil K. Spontaneous calcium transients in developing cortical neurons regulate axon outgrowth. J Neurosci 2003, 23:927-936.
40. Harish S., Sridharan D., Senthil Kumar S., Joseph J., Phani K.L.N. Barrier films to control loss of 9,10-anthraquinone-2-sulphonate dopant from PEDOT films during electrochemical transitions. Electrochim Acta 2009, 54:3618-3622.
41. Han Y.-K., Yih J.-N., Chang M.-Y., Huang W.-Y., Ho K.-S., Hsieh T.-H., et al. Facile synthesis of aqueous-dispersible nano-PEDOT: PSS-co-MA core/shell colloids through spray emulsion polymerization. Macromol Chem Phys 2011, 212:361-366.
42. Stöcker T., Köhler A., Moos R. Why does the electrical conductivity in PEDOT: PSS decrease with PSS content? A study combining thermoelectric measurements with impedance spectroscopy. J Polym Sci Part B Polym Phys 2012, 50:976-983.
43. Rafat M., Rotenstein L.S., You J.-O., Auguste D.T. Dual functionalized PVA hydrogels that adhere endothelial cells synergistically. Biomaterials 2012, 33:3880-3886.
44. Stauffer W.R., Cui X.T. Polypyrrole doped with 2 peptide sequences from laminin. Biomaterials 2006, 27:2405-2413.
45. Green R.A., Lovell N.H., Poole-Warren L.A. Impact of co-incorporating laminin peptide dopants and neurotrophic growth factors on conducting polymer properties. Acta Biomater 2010, 6:63-71.
46. Zhang L. Glycosaminoglycan (GAG) biosynthesis and GAG-binding proteins. Prog Mol Biol Transl Sci 2010, 93:1-17.
47. Cherry J.F., Carlson A.L., Benarba F.L., Sommerfeld S.D., Verma D., Loers G., et al. Oriented, multimeric biointerfaces of the L1 cell adhesion molecule: an approach to enhance neuronal and neural stem cell functions on 2-D and 3-D polymer substrates. Biointerphases 2012, 7:22.
48. Hirano S., Takeichi M. Cadherins in brain morphogenesis and wiring. Physiol Rev 2012, 92:597-634.
49. Nieto-Sampedro M., Collazos-Castro J.E., Taylor J.S., Gudiño-Cabrera G., Verdú-Navarro E., Pascual-Piédrola J.I., et al. Traumatic injuries to the central nervous system and their repair. Rev Neurol 2002, 35:534-552.
50. Collazos-Castro J.E., López-Dolado E., Nieto-Sampedro M. Locomotor deficits and adaptive mechanisms after thoracic spinal cord contusion in the adult rat. J Neurotrauma 2006, 23:1-17.
51. Aznar-Cervantes S., Roca M.I., Martinez J.G., Meseguer-Olmo L., Cenis J.L., Moraleda J.M., et al. Fabrication of conductive electrospun silk fibroin scaffolds by coating with polypyrrole for biomedical applications. Bioelectrochemistry 2012, 85:36-43.
52. Ku S.H., Lee S.H., Park C.B. Synergic effects of nanofiber alignment and electroactivity on myoblast differentiation. Biomaterials 2012, 33:6098-6104.
53. Schnell E., Klinkhammer K., Balzer S., Brook G., Klee D., Dalton P., et al. Guidance of glial cell migration and axonal growth on electrospun nanofibers of poly-epsilon-caprolactone and a collagen/poly-epsilon-caprolactone blend. Biomaterials 2007, 28:3012-3025.
54. Xie J., Macewan M.R., Willerth S.M., Li X., Moran D.W., Sakiyama-Elbert S.E., et al. Conductive core-sheath nanofibers and their potential application in neural tissue engineering. Adv Funct Mater 2009, 19:2312-2318.
55. Daud M.F., Pawar K.C., Claeyssens F., Ryan A.J., Haycock J.W. An aligned 3D neuronal-glial co-culture model for peripheral nerve studies. Biomaterials 2012, 33:5901-5913.
56. Hurtado A., Cregg J.M., Wang H.B., Wendell D.F., Oudega M., Gilbert R.J., et al. Robust CNS regeneration after complete spinal cord transection using aligned poly-L-lactic acid microfibers. Biomaterials 2011, 32:6068-6079.
57. Chen J., Wu J., Apostolova I., Skup M., Irintchev A., Kügler S., et al. Adeno-associated virus-mediated L1 expression promotes functional recovery after spinal cord injury. Brain 2007, 130:954-969.
58. Yue X.S., Murakami Y., Tamai T., Nagaoka M., Cho C.S., Ito Y., et al. A fusion protein N-cadherin-Fc as an artificial extracellular matrix surface for maintenance of stem cell features. Biomaterials 2010, 31:5287-5296.