Conducting polymers, dual neurotrophins and pulsed electrical stimulation - Dramatic effects on neurite outgrowth

Journal of Controlled Release

Volumn 141, Issue 2, 2010, Pages 161-167

  Thompson, Brianna C ^a   Richardson, Rachael T ^b,c   Moulton, Simon E ^a   Evans, Alison J ^b,c   O'Leary, Stephen ^b,c   Clark, Graeme M ^a,d   Wallace, Gordon G ^a  

^a UNIVERSITY OF WOLLONGONG   (Australia)

^b BIONIC EAR INSTITUTE   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d LA TROBE UNIVERSITY   (Australia)

Author keywords

Brain derived neurotrophic factor; Electrical stimulation; Neural engineering; Neurotrophin 3; Polypyrrole

Indexed keywords

BIOCOMPATIBLE SUBSTRATES; BRAIN-DERIVED NEUROTROPHIC FACTORS; COCHLEAR IMPLANT; ELECTRICAL STIMULATIONS; IODINE-125; NEURAL ENGINEERING; NEURITE OUTGROWTH; NEURITES; NEUROTROPHIN-3; NEUROTROPHINS; NOVEL POLYMERS; SENSORINEURAL HEARING LOSS; SYNERGISTIC EFFECT; TISSUE CULTURE PLASTICS;

AUDITION; CONDUCTING POLYMERS; CONDUCTIVE FILMS; CONDUCTIVE PLASTICS; IODINE; ORGANIC CONDUCTORS; POLYMER FILMS; POLYPYRROLES; TISSUE CULTURE;

ENZYME INHIBITION;

BRAIN DERIVED NEUROTROPHIC FACTOR; IODINE 125; NEUROTROPHIN 3; POLYPYRROLE;

ACOUSTIC NERVE FIBER; ANIMAL CELL; ARTICLE; CELL ELONGATION; CELL SURVIVAL; COCHLEAR NERVE; CONTROLLED STUDY; DRUG POTENTIATION; DRUG RELEASE; ELECTROSTIMULATION; EXPLANT; ISOTOPE LABELING; NERVE CONDUCTION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANIMALS, NEWBORN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL SURVIVAL; COCHLEAR NERVE; DRUG CARRIERS; DRUG COMBINATIONS; DRUG SYNERGISM; ELECTRIC CONDUCTIVITY; ELECTRIC STIMULATION; KINETICS; NEURITES; NEUROTROPHIN 3; POLYMERS; PYRROLES; RATS; RATS, WISTAR; SOLUBILITY; TISSUE CULTURE TECHNIQUES;

EID: 72149117668     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2009.09.016     Document Type: Article

References (29)

1. Hodgson A.J., Gilmore K.J., Small C., Wallace G.G., MacKenzie I., Ogata N., and Aoki T. Reactive supramolecular assemblies of mucopolysaccharide polypyrrole and protein as controllable biocomposites for a new generation of intelligent biomaterials. Supramol. Sci. 1 1 (1994) 77-83
2. Wong J.Y., Langer R., and Ingber D.E. Electrically conducting polymers can noninvasively control the shape and growth of mammalian cells. Proc. Natl. Acad. Sci. 91 (1994) 3201-3204
3. Kotwal A., and Schmidt C.E. Electrical stimulation alters protein adsorption and nerve cell interactions with electrically conducting biomaterials. Biomaterials 22 (2001) 1055-1064
4. Schmidt C.E., Shastri V.R., Vacanti J.P., and Langer R. Stimulation of neurite outgrowth using an electrically conducting polymer. Proc. Natl. Acad. Sci. 94 (1997) 8948-8953
5. Shastri V.R., Schmidt C.E., Kim H.T., Vacanti J.P., and Langer R. Polypyrrole - a potential candidate for stimulated nerve regeneration. Mat. Res. Soc. Proc. 414 (1996) 113-118
6. Liao H., Huang W.H., Niu R., Sun L.X., and Zhang L.Y. Cross-talk between the epidermal growth factor-like repeats/fibronectin 6-8 repeats domains of Tenascin-R and microglia modulates neural stem/progenitor cell proliferation and differentiation. J. Neurosci. Res. 86 (2008) 27-34
7. Zavan B., Abatangelo G., Mazzoleni F., Bassetto F., Cortivo R., and Vindigni V. New 3D hyaluronan-based scaffold for in vitro reconstruction of the rat sciatic nerve. Neurolog. Res. 30 (2008) 190-196
8. Cen L., Neoh K.G., Li Y., and Kang E.T. Assessment of in vitro bioactivity of hyaluronic acid and sulfated hyaluronic acid functionalized electroactive polymer. Biomacromolecules 5 (2004) 2238
9. Li Y., Neoh K.G., Cen L., and Kang E.T. Porous and electrically conductive polypyrrole-poly(vinyl alcohol) composite and its applications as a biomaterial. Langmuir 21 (2005) 10702-10709
10. Stauffer W.R., and Cui X.T. Polypyrrole doped with 2 peptide sequences from laminin. Biomaterials 27 (2006) 2405-2413
11. Chan O.C.M., So K.F., and Chan B.P. Fabrication of nano-fibrous collagen microspheres for protein delivery and effects of photochemical crosslinking on release kinetics. J. Control. Release 129 2 (2008) 135-143
12. Lee F., Chung J.E., and Kurisawa M. An injectable hyaluronic acid-tyramine hydrogel system for protein delivery. J. Control. Release 134 3 (2009) 186-193
13. Bezemer J.M., Grijpma D.W., Dijkstra P.J., van Blitterswijk C.A., and Feijen J. Control of protein delivery from amphiphilic poly(ether ester) multiblock copolymers by varying their water content using emulsification techniques. J. Control. Release 66 2-3 (2000) 307-320
14. Coue G., Feijen J., and Engbersen J.F.J. Development of biodegradable poly(amidoamine)s for protein delivery. J. Control. Release 132 3 (2008) e2-e3
15. Thompson B.C., Moulton S.E., Ding J., Richardson R., Cameron A., O'Leary S., Clark G.M., and Wallace G.G. Optimising the incorporation and release of a neurotrophic factor using conducting polypyrrole. J. Control. Release 116 (2006) 285-294
16. Richardson R., Thompson B.C., Moulton S.E., Cameron A., Wallace G.G., Kapsa R., Clark G.M., and O'Leary S. The effect of polypyrrole with incorporated neurotrophin-3 on the promotion of neurite outgrowth from auditory neurons. Biomaterials 28 (2007) 513-523
17. A.J. Evans, B.C. Thompson, G.G. Wallace, R.J. Millard, S. O'Leary, G.M. Clark, R.M. Shepherd, R.T. Richardson, Promoting neurite outgrowth from spiral ganglion neuron explants using polypyrrole/BDNF-coated electrodes, J. Biomed. Mater. Res. in press.
18. Gillespie L.N., Clark G.M., Bartlett P.F., and Marzella P.L. BDNF-induced survival of auditory neurons in vivo: cessation of treatment leads to accelerated loss of survival effects. J. Neurosci. Res. 71 (2003) 785-790
19. Miller J., Chi D., O'Keeffe L., Kruszka P., Raphael Y., and Altschuler R.A. Neurotrophins can enhance spiral ganglion cell survival after inner hair cell loss. Int. J. Dev. Neurosci 15 (1997) 631-643
20. Shepherd R.K., Coco A., Epp S.B., and Crook J.M. Chronic depolarization enhances the trophic effects of brain-derived neurotrophic factor in rescuing auditory neurons following a sensorineural hearing loss. J. Comp. Neurol. 486 (2005) 145-158
21. Staecker H., Kopke R., Malgrange B., Lefebvre P., and Van de Water T. NT-3 and/or BDNF therapy prevents loss of auditory neurons following loss of hair cells. Neuroreport 7 (1996) 889-894
22. Altschuler R.A., Cho Y., Ylikoski J., Pirvola U., Magal E., and Miller J.M. Ototoxicity: Basic Sci. Clinical Appl (1999) 305
23. Shinohara T., Bredberg G., Ulfendahl M., Pyykko I., Olivius N.P., Kaksonen R., Lindstrom B., Altschuler R., and Miller J.M. Neurotrophic factor intervention restores auditory function in deafened animals. Proc. Natl. Acad. Sci 99 (2002) 1657-1660
24. Wise A.K., Richardson R.T., Hardman J., Clark G.M., and O'Leary S. Resprouting and survival of guinea pig cochlear neurons in response to the administration of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3. J. Comp. Neurol. 487 (2005) 147-165
25. Shepherd R.K., Coco A., Epp S.B., and Crook J.M. Chronic depolarization enhances the trophic effects of brain-derived neurotrophic factor in rescuing auditory neurons following a sensorineural hearing loss. J. Comp. Neurol. 486 2 (2005) 145-158
26. Aletsee C., Mullen L., Kim D.H., Pak K., Brors D., Dazert S., and Ryan A.F. The disintegrin kistrin inhibits neurite extension from spiral ganglion explants cultured on laminin. Audiol. Neuro-Otol. 6 (2001) 57-65
27. Fritzsch B., Farinas I., and Reichardt L.F. Lack of neurotrophin 3 causes losses of both classes of spiral ganglion neurons in the cochlea in a region-specific fashion. J. Neurosci. 17 (1997) 6213-6225
28. Du J., Feng L., Yang F., and Lu B. Activity- and Ca(2+)-dependent modulation of surface expression of brain-derived neurotrophic factor receptors in hippocampal neurons. J. Cell Biol. 150 (2000) 1423-1434
29. Richardson R.T., Wise A.K., Thompson B.C., Flynn B.O., Atkinson P.J., Fretwell N.J., Fallon J.B., Wallace G.G., Shepherd R.K., Clark G.M., and O'Leary S.J. Polypyrrole-coated electrodes for the delivery of charge and neurotrophins to cochlear neurons. Biomaterials 30 13 (2009) 2614-2624