메뉴 건너뛰기




Volumn 24, Issue 2, 2013, Pages 123-131

Snail/Gfi-1 (SNAG) family zinc finger proteins in transcription regulation, chromatin dynamics, cell signaling, development, and disease

Author keywords

Cellular signaling and development; EMT and cancer; SNAG repression domain; SNAG ZFP target genes; Transcription regulation

Indexed keywords

HISTONE DEACETYLASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GFI 1; TRANSCRIPTION FACTOR SNAG; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG;

EID: 84875244569     PISSN: 13596101     EISSN: 18790305     Source Type: Journal    
DOI: 10.1016/j.cytogfr.2012.09.002     Document Type: Short Survey
Times cited : (65)

References (99)
  • 3
    • 46749157875 scopus 로고    scopus 로고
    • 2-zinc finger genes and subfamilies in mammals: species-specific duplication and loss of clusters, genes and effector domains
    • 2-zinc finger genes and subfamilies in mammals: species-specific duplication and loss of clusters, genes and effector domains. BMC Evolutionary Biology 2008, 8:176.
    • (2008) BMC Evolutionary Biology , vol.8 , pp. 176
    • Tadepally, H.D.1    Burger, G.2    Aubry, M.3
  • 4
    • 0040215628 scopus 로고
    • Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes
    • Miller J., McLachlan A.D., Klug A. Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO Journal 1985, 4:1609-1614.
    • (1985) EMBO Journal , vol.4 , pp. 1609-1614
    • Miller, J.1    McLachlan, A.D.2    Klug, A.3
  • 6
    • 34249299791 scopus 로고    scopus 로고
    • The complex language of chromatin regulation during transcription
    • Berger S.L. The complex language of chromatin regulation during transcription. Nature 2007, 447:407-412.
    • (2007) Nature , vol.447 , pp. 407-412
    • Berger, S.L.1
  • 7
    • 0029562736 scopus 로고
    • Purification and properties of an ATP-dependent nucleosome remodeling factor
    • Tsukiyama T., Wu C. Purification and properties of an ATP-dependent nucleosome remodeling factor. Cell 1995, 83:1011-1020.
    • (1995) Cell , vol.83 , pp. 1011-1020
    • Tsukiyama, T.1    Wu, C.2
  • 8
    • 0029978521 scopus 로고    scopus 로고
    • Active repression mechanisms of eukaryotic transcription repressors
    • Hanna-Rose W., Hansen U. Active repression mechanisms of eukaryotic transcription repressors. Trends in Genetics 1996, 12:229-234.
    • (1996) Trends in Genetics , vol.12 , pp. 229-234
    • Hanna-Rose, W.1    Hansen, U.2
  • 9
    • 0029656208 scopus 로고    scopus 로고
    • Unliganded thyroid hormone receptor alpha can target TATA-binding protein for transcriptional repression
    • Fondell J.D., Brunel F., Hisatake K., Roeder R.G. Unliganded thyroid hormone receptor alpha can target TATA-binding protein for transcriptional repression. Molecular and Cellular Biology 1996, 16:281-287.
    • (1996) Molecular and Cellular Biology , vol.16 , pp. 281-287
    • Fondell, J.D.1    Brunel, F.2    Hisatake, K.3    Roeder, R.G.4
  • 10
    • 0041624239 scopus 로고    scopus 로고
    • Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation
    • Ayyanathan K., Lechner M.S., Bell P., Maul G.G., Schultz D.C., Yamada Y., et al. Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation. Genes and Development 2003, 17:1855-1869.
    • (2003) Genes and Development , vol.17 , pp. 1855-1869
    • Ayyanathan, K.1    Lechner, M.S.2    Bell, P.3    Maul, G.G.4    Schultz, D.C.5    Yamada, Y.6
  • 11
    • 35148851978 scopus 로고    scopus 로고
    • The Ajuba LIM domain protein is a corepressor for SNAG domain mediated repression and participates in nucleocytoplasmic shuttling
    • Ayyanathan K., Peng H., Hou Z., Fredericks W.J., Goyal R.K., Langer E.M., et al. The Ajuba LIM domain protein is a corepressor for SNAG domain mediated repression and participates in nucleocytoplasmic shuttling. Cancer Research 2007, 67:9097-9106.
    • (2007) Cancer Research , vol.67 , pp. 9097-9106
    • Ayyanathan, K.1    Peng, H.2    Hou, Z.3    Fredericks, W.J.4    Goyal, R.K.5    Langer, E.M.6
  • 12
    • 0021220312 scopus 로고
    • Mutations and chromosomal rearrangements affecting the expression of Snail, a gene involved in embryonic patterning in Drosophila melanogaster
    • Grau Y., Carteret C., Simpson P. Mutations and chromosomal rearrangements affecting the expression of Snail, a gene involved in embryonic patterning in Drosophila melanogaster. Genetics 1984, 108:347-360.
    • (1984) Genetics , vol.108 , pp. 347-360
    • Grau, Y.1    Carteret, C.2    Simpson, P.3
  • 13
    • 0029806268 scopus 로고    scopus 로고
    • The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal
    • Grimes H.L., Chan T.O., Zweidler-McKay P.A., Tong B., Tsichlis P.N. The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal. Molecular and Cellular Biology 1996, 16:6263-6272.
    • (1996) Molecular and Cellular Biology , vol.16 , pp. 6263-6272
    • Grimes, H.L.1    Chan, T.O.2    Zweidler-McKay, P.A.3    Tong, B.4    Tsichlis, P.N.5
  • 14
    • 0034680368 scopus 로고    scopus 로고
    • Snail/slug family of repressors: slowly going into the fast lane of development and cancer
    • Hemavathy K., Ashraf S.I., Ip Y.T. Snail/slug family of repressors: slowly going into the fast lane of development and cancer. Gene 2000, 257:1-12.
    • (2000) Gene , vol.257 , pp. 1-12
    • Hemavathy, K.1    Ashraf, S.I.2    Ip, Y.T.3
  • 16
    • 0035312996 scopus 로고    scopus 로고
    • The increasing complexity of the Snail gene superfamily in metazoan evolution
    • Manzanares M., Locascio A., Nieto M.A. The increasing complexity of the Snail gene superfamily in metazoan evolution. Trends in Genetics 2001, 17:178-181.
    • (2001) Trends in Genetics , vol.17 , pp. 178-181
    • Manzanares, M.1    Locascio, A.2    Nieto, M.A.3
  • 17
    • 66449098550 scopus 로고    scopus 로고
    • Evolutionary history of the Snail/Scratch superfamily
    • Barrallo-Gimeno A., Nieto M.A. Evolutionary history of the Snail/Scratch superfamily. Trends in Genetics 2009, 25:248-252.
    • (2009) Trends in Genetics , vol.25 , pp. 248-252
    • Barrallo-Gimeno, A.1    Nieto, M.A.2
  • 18
    • 0028285316 scopus 로고
    • Genomic organization, 5'-upstream sequence, and chromosomal localization of an insulinoma-associated intronless gene, IA-1
    • Lan M.S., Li Q., Lu J., Modi W.S., Notkins A.L. Genomic organization, 5'-upstream sequence, and chromosomal localization of an insulinoma-associated intronless gene, IA-1. Journal of Biological Chemistry 1994, 269:14170-14174.
    • (1994) Journal of Biological Chemistry , vol.269 , pp. 14170-14174
    • Lan, M.S.1    Li, Q.2    Lu, J.3    Modi, W.S.4    Notkins, A.L.5
  • 19
    • 34548120890 scopus 로고    scopus 로고
    • Ol-insm1b, a SNAG family transcription factor involved in cell cycle arrest during medaka development
    • Candal E., Alunni A., Thermes V., Jamen F., Joly J.S., Bourrat F. Ol-insm1b, a SNAG family transcription factor involved in cell cycle arrest during medaka development. Developmental Biology 2007, 309:1-17.
    • (2007) Developmental Biology , vol.309 , pp. 1-17
    • Candal, E.1    Alunni, A.2    Thermes, V.3    Jamen, F.4    Joly, J.S.5    Bourrat, F.6
  • 20
    • 33746309504 scopus 로고    scopus 로고
    • Expression of two insm1-like genes in the developing zebrafish nervous system
    • Lukowski C.M., Ritzel R.G., Waskiewicz A.J. Expression of two insm1-like genes in the developing zebrafish nervous system. Gene Expression Patterns 2006, 6:711-718.
    • (2006) Gene Expression Patterns , vol.6 , pp. 711-718
    • Lukowski, C.M.1    Ritzel, R.G.2    Waskiewicz, A.J.3
  • 21
    • 0035114280 scopus 로고    scopus 로고
    • Identification of a novel member of the snail/Gfi-1 repressor family, mlt 1, which is methylated and silenced in liver tumors of SV40 T antigen transgenic mice
    • Tateno M., Fukunishi Y., Komatsu S., Okazaki Y., Kawai J., Shibata K., et al. Identification of a novel member of the snail/Gfi-1 repressor family, mlt 1, which is methylated and silenced in liver tumors of SV40 T antigen transgenic mice. Cancer Research 2001, 61:1144-1153.
    • (2001) Cancer Research , vol.61 , pp. 1144-1153
    • Tateno, M.1    Fukunishi, Y.2    Komatsu, S.3    Okazaki, Y.4    Kawai, J.5    Shibata, K.6
  • 22
    • 34247176148 scopus 로고    scopus 로고
    • Ovol1 represses its own transcription by competing with transcription activator c-Myb and by recruiting histone deacetylase activity
    • Nair M., Bilanchone V., Ortt K., Sinha S., Dai X. Ovol1 represses its own transcription by competing with transcription activator c-Myb and by recruiting histone deacetylase activity. Nucleic Acids Research 2007, 35:1687-1697.
    • (2007) Nucleic Acids Research , vol.35 , pp. 1687-1697
    • Nair, M.1    Bilanchone, V.2    Ortt, K.3    Sinha, S.4    Dai, X.5
  • 23
    • 84860465552 scopus 로고    scopus 로고
    • Characterization of the SNAG and SLUG domains of Snail2 in the repression of E-cadherin and EMT induction: modulation by serine 4 phosphorylation
    • Molina-Ortiz P., Villarejo A., MacPherson M., Santos V., Montes A., Souchelnytskyi S., et al. Characterization of the SNAG and SLUG domains of Snail2 in the repression of E-cadherin and EMT induction: modulation by serine 4 phosphorylation. PLoS One 2012, 7:e36132.
    • (2012) PLoS One , vol.7
    • Molina-Ortiz, P.1    Villarejo, A.2    MacPherson, M.3    Santos, V.4    Montes, A.5    Souchelnytskyi, S.6
  • 24
    • 43249086048 scopus 로고    scopus 로고
    • The LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repression
    • Hou Z., Peng H., Ayyanathan K., Yan K., Langer E.M., Longmore G.D., et al. The LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repression. Molecular and Cellular Biology 2008, 28:3198-3207.
    • (2008) Molecular and Cellular Biology , vol.28 , pp. 3198-3207
    • Hou, Z.1    Peng, H.2    Ayyanathan, K.3    Yan, K.4    Langer, E.M.5    Longmore, G.D.6
  • 25
  • 26
    • 57649115445 scopus 로고    scopus 로고
    • Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor
    • Montoya-Durango D.E., Velu C.S., Kazanjian A., Rojas M.E.B., Jay C.M., Longmore G.D., et al. Ajuba functions as a histone deacetylase-dependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor. Journal of Biological Chemistry 2008, 283:32056-32065.
    • (2008) Journal of Biological Chemistry , vol.283 , pp. 32056-32065
    • Montoya-Durango, D.E.1    Velu, C.S.2    Kazanjian, A.3    Rojas, M.E.B.4    Jay, C.M.5    Longmore, G.D.6
  • 27
    • 77953107054 scopus 로고    scopus 로고
    • The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1
    • Lin Y., Wu Y., Li J., Dong C., Ye X., Chi Y., et al. The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine-specific demethylase 1. EMBO Journal 2010, 29:1803-1816.
    • (2010) EMBO Journal , vol.29 , pp. 1803-1816
    • Lin, Y.1    Wu, Y.2    Li, J.3    Dong, C.4    Ye, X.5    Chi, Y.6
  • 28
    • 34547785073 scopus 로고    scopus 로고
    • Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1
    • Saleque S., Kim J., Rooke H.M., Orkin S.H. Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1. Molecular Cell 2007, 27:562-572.
    • (2007) Molecular Cell , vol.27 , pp. 562-572
    • Saleque, S.1    Kim, J.2    Rooke, H.M.3    Orkin, S.H.4
  • 29
    • 84861214055 scopus 로고    scopus 로고
    • A short Gfi-1B isoform controls erythroid differentiation by recruiting the LSD1-CoREST complex through the dimethylation of its SNAG domain
    • Laurent B., Randrianarison-Huetz V., Frisan E., Andrieu-Soler C., Soler E., Fontenay M., et al. A short Gfi-1B isoform controls erythroid differentiation by recruiting the LSD1-CoREST complex through the dimethylation of its SNAG domain. Journal of Cell Science 2012, 125:993-1002.
    • (2012) Journal of Cell Science , vol.125 , pp. 993-1002
    • Laurent, B.1    Randrianarison-Huetz, V.2    Frisan, E.3    Andrieu-Soler, C.4    Soler, E.5    Fontenay, M.6
  • 30
    • 1942425459 scopus 로고    scopus 로고
    • The repressor function of snail is required for Drosophila gastrulation and is not replaceable by Escargot or Worniu
    • Hemavathy K., Hu X., Ashraf S.I., Small S.J., Ip Y.T. The repressor function of snail is required for Drosophila gastrulation and is not replaceable by Escargot or Worniu. Developmental Biology 2004, 269:411-420.
    • (2004) Developmental Biology , vol.269 , pp. 411-420
    • Hemavathy, K.1    Hu, X.2    Ashraf, S.I.3    Small, S.J.4    Ip, Y.T.5
  • 31
    • 0032403085 scopus 로고    scopus 로고
    • DCtBP mediates transcriptional repression by Knirps, Kruppel and Snail in the Drosophila embryo
    • Nibu Y., Zhang H., Bajor E., Barolo S., Small S., Levine M. dCtBP mediates transcriptional repression by Knirps, Kruppel and Snail in the Drosophila embryo. EMBO Journal 1998, 17:7009-7020.
    • (1998) EMBO Journal , vol.17 , pp. 7009-7020
    • Nibu, Y.1    Zhang, H.2    Bajor, E.3    Barolo, S.4    Small, S.5    Levine, M.6
  • 32
    • 0033013868 scopus 로고    scopus 로고
    • KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing
    • Ryan R.F., Schultz D.C., Ayyanathan K., Singh P.B., Friedman J.R., Fredericks W.J., et al. KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Kruppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing. Molecular and Cellular Biology 1999, 19:4366-4378.
    • (1999) Molecular and Cellular Biology , vol.19 , pp. 4366-4378
    • Ryan, R.F.1    Schultz, D.C.2    Ayyanathan, K.3    Singh, P.B.4    Friedman, J.R.5    Fredericks, W.J.6
  • 33
    • 84856533341 scopus 로고    scopus 로고
    • EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin
    • Tong Z.T., Cai M.Y., Wang X.G., Kong L.L., Mai S.J., Liu Y.H., et al. EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin. Oncogene 2012, 31:583-594.
    • (2012) Oncogene , vol.31 , pp. 583-594
    • Tong, Z.T.1    Cai, M.Y.2    Wang, X.G.3    Kong, L.L.4    Mai, S.J.5    Liu, Y.H.6
  • 34
    • 27944504221 scopus 로고    scopus 로고
    • Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1
    • Duan Z., Zarebski A., Montoya-Durango D., Grimes H.L., Horwitz M. Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1. Molecular and Cellular Biology 2005, 25:10338-10351.
    • (2005) Molecular and Cellular Biology , vol.25 , pp. 10338-10351
    • Duan, Z.1    Zarebski, A.2    Montoya-Durango, D.3    Grimes, H.L.4    Horwitz, M.5
  • 35
    • 0042769321 scopus 로고    scopus 로고
    • Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism
    • McGhee L., Bryan J., Elliott L., Grimes H.L., Kazanjian A., Davis J.N., et al. Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism. Journal of Cellular Biochemistry 2003, 89:1005-1018.
    • (2003) Journal of Cellular Biochemistry , vol.89 , pp. 1005-1018
    • McGhee, L.1    Bryan, J.2    Elliott, L.3    Grimes, H.L.4    Kazanjian, A.5    Davis, J.N.6
  • 36
    • 33745556537 scopus 로고    scopus 로고
    • INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases
    • Liu W.D., Wang H.W., Muguira M., Breslin M.B., Lan M.S. INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases. Biochemical Journal 2006, 397:169-177.
    • (2006) Biochemical Journal , vol.397 , pp. 169-177
    • Liu, W.D.1    Wang, H.W.2    Muguira, M.3    Breslin, M.B.4    Lan, M.S.5
  • 37
    • 0027184973 scopus 로고
    • Definition of the DNA-binding site repertoire for the Drosophila transcription factor SNAIL
    • Mauhin V., Lutz Y., Dennefeld C., Alberga A. Definition of the DNA-binding site repertoire for the Drosophila transcription factor SNAIL. Nucleic Acids Research 1993, 21:3951-3957.
    • (1993) Nucleic Acids Research , vol.21 , pp. 3951-3957
    • Mauhin, V.1    Lutz, Y.2    Dennefeld, C.3    Alberga, A.4
  • 38
    • 0033197879 scopus 로고    scopus 로고
    • SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein
    • Inukai T., Inoue A., Kurosawa H., Goi K., Shinjyo T., Ozawa K., et al. SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein. Molecular Cell 1999, 4:343-352.
    • (1999) Molecular Cell , vol.4 , pp. 343-352
    • Inukai, T.1    Inoue, A.2    Kurosawa, H.3    Goi, K.4    Shinjyo, T.5    Ozawa, K.6
  • 40
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • Cano A., Perez-Moreno M.A., Rodrigo I., Locascio A., Blanco M.J., del Barrio M.G., et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nature Cell Biology 2000, 2:76-83.
    • (2000) Nature Cell Biology , vol.2 , pp. 76-83
    • Cano, A.1    Perez-Moreno, M.A.2    Rodrigo, I.3    Locascio, A.4    Blanco, M.J.5    del Barrio, M.G.6
  • 42
    • 0034650716 scopus 로고    scopus 로고
    • A novel snail-related transcription factor Smuc regulates basic helix-loop-helix transcription factor activities via specific E-box motifs
    • Kataoka H., Murayama T., Yokode M., Mori S., Sano H., Ozaki H., et al. A novel snail-related transcription factor Smuc regulates basic helix-loop-helix transcription factor activities via specific E-box motifs. Nucleic Acids Research 2000, 28:626-633.
    • (2000) Nucleic Acids Research , vol.28 , pp. 626-633
    • Kataoka, H.1    Murayama, T.2    Yokode, M.3    Mori, S.4    Sano, H.5    Ozaki, H.6
  • 43
    • 33645909102 scopus 로고    scopus 로고
    • Snail1 transcriptional repressor binds to its own promoter and controls its expression
    • Peiro S., Escriva M., Puig I., Barbera M.J., Dave N., Herranz N., et al. Snail1 transcriptional repressor binds to its own promoter and controls its expression. Nucleic Acids Research 2006, 34:2077-2084.
    • (2006) Nucleic Acids Research , vol.34 , pp. 2077-2084
    • Peiro, S.1    Escriva, M.2    Puig, I.3    Barbera, M.J.4    Dave, N.5    Herranz, N.6
  • 44
    • 0141755155 scopus 로고    scopus 로고
    • NeuroD1/E47 regulates the E-box element of a novel zinc finger transcription factor, IA-1, in developing nervous system
    • Breslin M.B., Zhu M., Lan M.S. NeuroD1/E47 regulates the E-box element of a novel zinc finger transcription factor, IA-1, in developing nervous system. Journal of Biological Chemistry 2003, 278:38991-38997.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 38991-38997
    • Breslin, M.B.1    Zhu, M.2    Lan, M.S.3
  • 45
    • 0029897536 scopus 로고    scopus 로고
    • Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor
    • Zweidler-Mckay P.A., Grimes H.L., Flubacher M.M., Tsichlis P.N. Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor. Molecular and Cellular Biology 1996, 16:4024-4034.
    • (1996) Molecular and Cellular Biology , vol.16 , pp. 4024-4034
    • Zweidler-Mckay, P.A.1    Grimes, H.L.2    Flubacher, M.M.3    Tsichlis, P.N.4
  • 47
    • 13244252714 scopus 로고    scopus 로고
    • Gfi-1 takes center stage in hematopoietic stem cells
    • Duan Z., Horwitz M. Gfi-1 takes center stage in hematopoietic stem cells. Trends in Molecular Medicine 2005, 11:49-52.
    • (2005) Trends in Molecular Medicine , vol.11 , pp. 49-52
    • Duan, Z.1    Horwitz, M.2
  • 48
    • 0031895515 scopus 로고    scopus 로고
    • The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation
    • Tong B., Grimes H.L., Yang T.Y., Bear S.E., Qin Z., Du K., et al. The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation. Molecular and Cellular Biology 1998, 18:2462-2473.
    • (1998) Molecular and Cellular Biology , vol.18 , pp. 2462-2473
    • Tong, B.1    Grimes, H.L.2    Yang, T.Y.3    Bear, S.E.4    Qin, Z.5    Du, K.6
  • 49
    • 14244258985 scopus 로고    scopus 로고
    • Direct transcriptional repression of the genes encoding the zinc-finger proteins Gfi1b and Gfi1 by Gfi1b
    • Vassen L., Fiolka K., Mahlmann S., Moroy T. Direct transcriptional repression of the genes encoding the zinc-finger proteins Gfi1b and Gfi1 by Gfi1b. Nucleic Acids Research 2005, 33:987-998.
    • (2005) Nucleic Acids Research , vol.33 , pp. 987-998
    • Vassen, L.1    Fiolka, K.2    Mahlmann, S.3    Moroy, T.4
  • 50
    • 0037082431 scopus 로고    scopus 로고
    • Neuroendocrine differentiation factor, IA-1, is a transcriptional repressor and contains a specific DNA-binding domain: identification of consensus IA-1 binding sequence
    • Breslin M.B., Zhu M., Notkins A.L., Lan M.S. Neuroendocrine differentiation factor, IA-1, is a transcriptional repressor and contains a specific DNA-binding domain: identification of consensus IA-1 binding sequence. Nucleic Acids Research 2002, 30:1038-1045.
    • (2002) Nucleic Acids Research , vol.30 , pp. 1038-1045
    • Breslin, M.B.1    Zhu, M.2    Notkins, A.L.3    Lan, M.S.4
  • 51
    • 47849099626 scopus 로고    scopus 로고
    • Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription
    • Wang H.W., Muguira M., Liu W.D., Zhang T., Chen C., Aucoin R., et al. Identification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcription. Journal of Endocrinology 2008, 198:29-39.
    • (2008) Journal of Endocrinology , vol.198 , pp. 29-39
    • Wang, H.W.1    Muguira, M.2    Liu, W.D.3    Zhang, T.4    Chen, C.5    Aucoin, R.6
  • 52
    • 84875252247 scopus 로고    scopus 로고
    • Characterization of the E-box binding affi{ligature}nity to SNAG-zinc fi{ligature}nger proteins
    • Chiang C., Ayyanathan K. Characterization of the E-box binding affi{ligature}nity to SNAG-zinc fi{ligature}nger proteins. Molekulyarnaya Biologiya 2012, 46:1-8.
    • (2012) Molekulyarnaya Biologiya , vol.46 , pp. 1-8
    • Chiang, C.1    Ayyanathan, K.2
  • 53
    • 34249289041 scopus 로고    scopus 로고
    • Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
    • Peinado H., Olmeda D., Cano A. Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?. Nature Reviews Cancer 2007, 7:415-428.
    • (2007) Nature Reviews Cancer , vol.7 , pp. 415-428
    • Peinado, H.1    Olmeda, D.2    Cano, A.3
  • 55
    • 0033789680 scopus 로고    scopus 로고
    • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
    • Batlle E., Sancho E., Franci C., Dominguez D., Monfar M., Baulida J., et al. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nature Cell Biology 2000, 2:84-89.
    • (2000) Nature Cell Biology , vol.2 , pp. 84-89
    • Batlle, E.1    Sancho, E.2    Franci, C.3    Dominguez, D.4    Monfar, M.5    Baulida, J.6
  • 56
    • 12944260524 scopus 로고    scopus 로고
    • Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes
    • Savagner P., Kusewitt D.F., Carver E.A., Magnino F., Choi C., Gridley T., et al. Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes. Journal of Cellular Physiology 2005, 202:858-866.
    • (2005) Journal of Cellular Physiology , vol.202 , pp. 858-866
    • Savagner, P.1    Kusewitt, D.F.2    Carver, E.A.3    Magnino, F.4    Choi, C.5    Gridley, T.6
  • 57
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors
    • Bolos V., Peinado H., Perez-Moreno M.A., Fraga M.F., Esteller M., Cano A. The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. Journal of Cell Science 2003, 116:499-511.
    • (2003) Journal of Cell Science , vol.116 , pp. 499-511
    • Bolos, V.1    Peinado, H.2    Perez-Moreno, M.A.3    Fraga, M.F.4    Esteller, M.5    Cano, A.6
  • 58
    • 0037086277 scopus 로고    scopus 로고
    • The SLUG zinc-finger protein represses E-cadherin in breast cancer
    • Hajra K.M., Chen D.Y., Fearon E.R. The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Research 2002, 62:1613-1618.
    • (2002) Cancer Research , vol.62 , pp. 1613-1618
    • Hajra, K.M.1    Chen, D.Y.2    Fearon, E.R.3
  • 59
    • 5444269904 scopus 로고    scopus 로고
    • Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition
    • Zhou B.P., Deng J., Xia W., Xu J., Li Y.M., Gunduz M., et al. Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition. Nature Cell Biology 2004, 6:931-940.
    • (2004) Nature Cell Biology , vol.6 , pp. 931-940
    • Zhou, B.P.1    Deng, J.2    Xia, W.3    Xu, J.4    Li, Y.M.5    Gunduz, M.6
  • 62
    • 0346363757 scopus 로고    scopus 로고
    • Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex
    • Peinado H., Ballestar E., Esteller M., Cano A. Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex. Molecular and Cellular Biology 2004, 24:306-319.
    • (2004) Molecular and Cellular Biology , vol.24 , pp. 306-319
    • Peinado, H.1    Ballestar, E.2    Esteller, M.3    Cano, A.4
  • 63
    • 84875231385 scopus 로고    scopus 로고
    • Interaction with Suv39H1 is critical for Snail mediated E-cadherin repression in breast cancer
    • Dong C., Wu Y., Wang Y., Wang C., Kang T., Rychahou P.G., et al. Interaction with Suv39H1 is critical for Snail mediated E-cadherin repression in breast cancer. Oncogene 2012, 169:1-12.
    • (2012) Oncogene , vol.169 , pp. 1-12
    • Dong, C.1    Wu, Y.2    Wang, Y.3    Wang, C.4    Kang, T.5    Rychahou, P.G.6
  • 64
    • 33947528384 scopus 로고    scopus 로고
    • Snail silencing effectively suppresses tumour growth and invasiveness
    • Olmeda D., Jorda M., Peinado H., Fabra A., Cano A. Snail silencing effectively suppresses tumour growth and invasiveness. Oncogene 2007, 26:1862-1874.
    • (2007) Oncogene , vol.26 , pp. 1862-1874
    • Olmeda, D.1    Jorda, M.2    Peinado, H.3    Fabra, A.4    Cano, A.5
  • 66
    • 21244437500 scopus 로고    scopus 로고
    • Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer
    • Martin T.A., Goyal A., Watkins G., Jiang W.G. Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer. Annals of Surgical Oncology 2005, 12:488-496.
    • (2005) Annals of Surgical Oncology , vol.12 , pp. 488-496
    • Martin, T.A.1    Goyal, A.2    Watkins, G.3    Jiang, W.G.4
  • 67
    • 85047698213 scopus 로고    scopus 로고
    • Correlation of Snail expression with histological grade and lymph node status in breast carcinomas
    • Blanco M.J., Moreno-Bueno G., Sarrio D., Locascio A., Cano A., Palacios J., et al. Correlation of Snail expression with histological grade and lymph node status in breast carcinomas. Oncogene 2002, 21:3241-3246.
    • (2002) Oncogene , vol.21 , pp. 3241-3246
    • Blanco, M.J.1    Moreno-Bueno, G.2    Sarrio, D.3    Locascio, A.4    Cano, A.5    Palacios, J.6
  • 69
    • 14844297318 scopus 로고    scopus 로고
    • Snail accelerates cancer invasion by upregulating MMP expression and is associated with poor prognosis of hepatocellular carcinoma
    • Miyoshi A., Kitajima Y., Kido S., Shimonishi T., Matsuyama S., Kitahara K., et al. Snail accelerates cancer invasion by upregulating MMP expression and is associated with poor prognosis of hepatocellular carcinoma. British Journal of Cancer 2005, 92:252-258.
    • (2005) British Journal of Cancer , vol.92 , pp. 252-258
    • Miyoshi, A.1    Kitajima, Y.2    Kido, S.3    Shimonishi, T.4    Matsuyama, S.5    Kitahara, K.6
  • 72
    • 78349273712 scopus 로고    scopus 로고
    • Slug inhibits proliferation of human prostate cancer cells via downregulation of cyclin D1 expression
    • Liu J., Uygur B., Zhang Z., Shao L., Romero D., Vary C., et al. Slug inhibits proliferation of human prostate cancer cells via downregulation of cyclin D1 expression. Prostate 2010, 70:1768-1777.
    • (2010) Prostate , vol.70 , pp. 1768-1777
    • Liu, J.1    Uygur, B.2    Zhang, Z.3    Shao, L.4    Romero, D.5    Vary, C.6
  • 74
    • 68549099889 scopus 로고    scopus 로고
    • Structure, expression, and biological function of INSM1 transcription factor in neuroendocrine differentiation
    • Lan M.S., Breslin M.B. Structure, expression, and biological function of INSM1 transcription factor in neuroendocrine differentiation. FASEB Journal 2009, 23:2024-2033.
    • (2009) FASEB Journal , vol.23 , pp. 2024-2033
    • Lan, M.S.1    Breslin, M.B.2
  • 75
    • 33645016881 scopus 로고    scopus 로고
    • The insulinoma-associated 1: a novel promoter for targeted cancer gene therapy for small-cell lung cancer
    • Pedersen N., Pedersen M.W., Lan M.S., Breslin M.B., Poulsen H.S. The insulinoma-associated 1: a novel promoter for targeted cancer gene therapy for small-cell lung cancer. Cancer Gene Therapy 2006, 13:375-384.
    • (2006) Cancer Gene Therapy , vol.13 , pp. 375-384
    • Pedersen, N.1    Pedersen, M.W.2    Lan, M.S.3    Breslin, M.B.4    Poulsen, H.S.5
  • 76
    • 0027818834 scopus 로고
    • IA-1, a new marker for neuroendocrine differentiation in human lung cancer cell lines
    • Lan M.S., Russell E.K., Lu J., Johnson B.E., Notkins A.L. IA-1, a new marker for neuroendocrine differentiation in human lung cancer cell lines. Cancer Research 1993, 53:4169-4171.
    • (1993) Cancer Research , vol.53 , pp. 4169-4171
    • Lan, M.S.1    Russell, E.K.2    Lu, J.3    Johnson, B.E.4    Notkins, A.L.5
  • 77
    • 20444466497 scopus 로고    scopus 로고
    • The transcriptional repressor Gfi1 controls STAT3-dependent dendritic cell development and function
    • Rathinam C., Geffers R., Yucel R., Buer J., Welte K., Moroy T., et al. The transcriptional repressor Gfi1 controls STAT3-dependent dendritic cell development and function. Immunity 2005, 22:717-728.
    • (2005) Immunity , vol.22 , pp. 717-728
    • Rathinam, C.1    Geffers, R.2    Yucel, R.3    Buer, J.4    Welte, K.5    Moroy, T.6
  • 78
    • 0013201680 scopus 로고    scopus 로고
    • Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1
    • Karsunky H., Zeng H., Schmidt T., Zevnik B., Kluge R., Schmid K.W., et al. Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1. Nature Genetics 2002, 28:28.
    • (2002) Nature Genetics , vol.28 , pp. 28
    • Karsunky, H.1    Zeng, H.2    Schmidt, T.3    Zevnik, B.4    Kluge, R.5    Schmid, K.W.6
  • 79
    • 41649106096 scopus 로고    scopus 로고
    • The zinc finger protein and transcriptional repressor Gfi1 as a regulator of the innate immune response
    • Moroy T., Zeng H., Jin J., Schmid K.W., Carpinteiro A., Gulbins E. The zinc finger protein and transcriptional repressor Gfi1 as a regulator of the innate immune response. Immunobiology 2008, 213:341-352.
    • (2008) Immunobiology , vol.213 , pp. 341-352
    • Moroy, T.1    Zeng, H.2    Jin, J.3    Schmid, K.W.4    Carpinteiro, A.5    Gulbins, E.6
  • 80
    • 33746195568 scopus 로고    scopus 로고
    • The growth factor independence-1 transcription factor: new functions and new insights
    • Kazanjian A., Gross E.A., Grimes H.L. The growth factor independence-1 transcription factor: new functions and new insights. Critical Reviews in Oncology/Hematology 2006, 59:85-97.
    • (2006) Critical Reviews in Oncology/Hematology , vol.59 , pp. 85-97
    • Kazanjian, A.1    Gross, E.A.2    Grimes, H.L.3
  • 82
    • 4344662447 scopus 로고    scopus 로고
    • Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress
    • Kajita M., McClinic K.N., Wade P.A. Aberrant expression of the transcription factors snail and slug alters the response to genotoxic stress. Molecular and Cellular Biology 2004, 24:7559-7566.
    • (2004) Molecular and Cellular Biology , vol.24 , pp. 7559-7566
    • Kajita, M.1    McClinic, K.N.2    Wade, P.A.3
  • 83
    • 0036513626 scopus 로고    scopus 로고
    • The snail superfamily of zinc-finger transcription factors
    • Nieto M.A. The snail superfamily of zinc-finger transcription factors. Nature Reviews Molecular Cell Biology 2002, 3:155-166.
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , pp. 155-166
    • Nieto, M.A.1
  • 84
    • 34249035916 scopus 로고    scopus 로고
    • Multiple functions of Snail family genes during palate development in mice
    • Murray S.A., Oram K.F., Gridley T. Multiple functions of Snail family genes during palate development in mice. Development 2007, 134:1789-1797.
    • (2007) Development , vol.134 , pp. 1789-1797
    • Murray, S.A.1    Oram, K.F.2    Gridley, T.3
  • 85
    • 0028318730 scopus 로고
    • Control of cell behavior during vertebrate development by Slug, a zinc finger gene
    • Nieto M.A., Sargent M.G., Wilkinson D.G., Cooke J. Control of cell behavior during vertebrate development by Slug, a zinc finger gene. Science 1994, 264:835-839.
    • (1994) Science , vol.264 , pp. 835-839
    • Nieto, M.A.1    Sargent, M.G.2    Wilkinson, D.G.3    Cooke, J.4
  • 86
    • 33748329757 scopus 로고    scopus 로고
    • The expression of Scratch genes in the developing and adult brain
    • Marin F., Nieto M.A. The expression of Scratch genes in the developing and adult brain. Developmental Dynamics 2006, 235:2586-2591.
    • (2006) Developmental Dynamics , vol.235 , pp. 2586-2591
    • Marin, F.1    Nieto, M.A.2
  • 87
    • 33645766023 scopus 로고    scopus 로고
    • Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development
    • Fiolka K., Hertzano R., Vassen L., Zeng H., Hermesh O., Avraham K.B.N., et al. Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development. EMBO Reports 2006, 7:326-333.
    • (2006) EMBO Reports , vol.7 , pp. 326-333
    • Fiolka, K.1    Hertzano, R.2    Vassen, L.3    Zeng, H.4    Hermesh, O.5    Avraham, K.B.N.6
  • 88
    • 33748251457 scopus 로고    scopus 로고
    • The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells
    • Gierl M.S., Karoulias N., Wende H., Strehle M., Birchmeier C. The zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cells. Genes and Development 2006, 20:2465-2478.
    • (2006) Genes and Development , vol.20 , pp. 2465-2478
    • Gierl, M.S.1    Karoulias, N.2    Wende, H.3    Strehle, M.4    Birchmeier, C.5
  • 89
    • 40749145752 scopus 로고    scopus 로고
    • Transient expression of the conserved zinc finger gene INSM1 in progenitors and nascent neurons throughout embryonic and adult neurogenesis
    • Duggan A., Madathany T., de Castro S.C., Gerrelli D., Guddati K., Garcia-Anoveros J. Transient expression of the conserved zinc finger gene INSM1 in progenitors and nascent neurons throughout embryonic and adult neurogenesis. Journal of Comparative Neurology 2008, 507:1497-1520.
    • (2008) Journal of Comparative Neurology , vol.507 , pp. 1497-1520
    • Duggan, A.1    Madathany, T.2    de Castro, S.C.3    Gerrelli, D.4    Guddati, K.5    Garcia-Anoveros, J.6
  • 90
    • 53049106922 scopus 로고    scopus 로고
    • Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex
    • Farkas L.M., Haffner C., Giger T., Khaitovich P., Nowick K., Birchmeier C., et al. Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron 2008, 60:40-55.
    • (2008) Neuron , vol.60 , pp. 40-55
    • Farkas, L.M.1    Haffner, C.2    Giger, T.3    Khaitovich, P.4    Nowick, K.5    Birchmeier, C.6
  • 93
    • 34447096563 scopus 로고    scopus 로고
    • Zinc-finger transcription factor snail accelerates survival, migration and expression of matrix metalloproteinase-2 in human bone mesenchymal stem cells
    • Zha Y.H., He J.F., Mei Y.W., Yin T., Mao L. Zinc-finger transcription factor snail accelerates survival, migration and expression of matrix metalloproteinase-2 in human bone mesenchymal stem cells. Cell Biology International 2007, 31:1089-1096.
    • (2007) Cell Biology International , vol.31 , pp. 1089-1096
    • Zha, Y.H.1    He, J.F.2    Mei, Y.W.3    Yin, T.4    Mao, L.5
  • 94
    • 0037108193 scopus 로고    scopus 로고
    • Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis
    • Osawa M., Yamaguchi T., Nakamura Y., Kaneko S., Onodera M., Sawada K., et al. Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis. Blood 2002, 100:2769-2777.
    • (2002) Blood , vol.100 , pp. 2769-2777
    • Osawa, M.1    Yamaguchi, T.2    Nakamura, Y.3    Kaneko, S.4    Onodera, M.5    Sawada, K.6
  • 95
    • 33947251378 scopus 로고    scopus 로고
    • Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1
    • Vassen L., Okayama T., Moroy T. Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1. Blood 2007, 109:2356-2364.
    • (2007) Blood , vol.109 , pp. 2356-2364
    • Vassen, L.1    Okayama, T.2    Moroy, T.3
  • 96
    • 13544273833 scopus 로고    scopus 로고
    • Gfi-1B plays a critical role in terminal differentiation of normal and transformed erythroid progenitor cells
    • Garcon L., Lacout C., Svinartchouk F., Le Couedic J.P., Villeval J.L., Vainchenker W., et al. Gfi-1B plays a critical role in terminal differentiation of normal and transformed erythroid progenitor cells. Blood 2005, 105:1448-1455.
    • (2005) Blood , vol.105 , pp. 1448-1455
    • Garcon, L.1    Lacout, C.2    Svinartchouk, F.3    Le Couedic, J.P.4    Villeval, J.L.5    Vainchenker, W.6
  • 97
    • 0037127270 scopus 로고    scopus 로고
    • Regulation of Socs gene expression by the proto-oncoprotein GFI-1B: two routes for STAT5 target gene induction by erythropoietin
    • Jegalian A.G., Wu H. Regulation of Socs gene expression by the proto-oncoprotein GFI-1B: two routes for STAT5 target gene induction by erythropoietin. Journal of Biological Chemistry 2002, 277:2345-2352.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 2345-2352
    • Jegalian, A.G.1    Wu, H.2
  • 98
    • 77953147456 scopus 로고    scopus 로고
    • Insulinoma-associated antigen-1 zinc-finger transcription factor promotes pancreatic duct cell trans-differentiation
    • Zhang T., Wang H., Saunee N.A., Breslin M.B., Lan M.S. Insulinoma-associated antigen-1 zinc-finger transcription factor promotes pancreatic duct cell trans-differentiation. Endocrinology 2010, 151:2030-2039.
    • (2010) Endocrinology , vol.151 , pp. 2030-2039
    • Zhang, T.1    Wang, H.2    Saunee, N.A.3    Breslin, M.B.4    Lan, M.S.5
  • 99
    • 33646076202 scopus 로고    scopus 로고
    • Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcription
    • Nair M., Teng A., Bilanchone V., Agrawal A., Li B., Dai X. Ovol1 regulates the growth arrest of embryonic epidermal progenitor cells and represses c-myc transcription. Journal of Cell Biology 2006, 173:253-264.
    • (2006) Journal of Cell Biology , vol.173 , pp. 253-264
    • Nair, M.1    Teng, A.2    Bilanchone, V.3    Agrawal, A.4    Li, B.5    Dai, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.