The SNAIL family member SCRATCH1 is not expressed in human tumors

Oncology Reports

Volumn 23, Issue 2, 2010, Pages 523-529

  Bastid, Jérémy ^a,b,c   Bouchet, Benjamin Pierre ^a,b,c   Ciancia, Claire ^a,b,c   Pourchet, Julie ^a,b   Audoynaud, Carole ^b   Grelier, Gaël ^a,b   Puisieux, Alain ^a,b,c   Ansieau, Stéphane ^a,b  

^a INSERM   (France)

^b CENTRE LÉON BÉRARD   (France)

^c UNIVERSITÉ LYON 1   (France)

Author keywords

Epithelial mesenchymal transition; SCRATCH; SNAIL transcription factors; Tumorigenesis

Indexed keywords

PROTEIN SCRT1; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CARCINOMA; CONTROLLED STUDY; GENETIC ANALYSIS; LUNG CANCER; MELANOMA; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; CARCINOMA; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MAMMARY NEOPLASMS, ANIMAL; MELANOMA; MICE; NEOPLASMS; TRANSCRIPTION FACTORS;

EID: 76649144221     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or-00000665     Document Type: Article

References (38)

1. Lee JM, Dedhar S, Kalluri R and Thompson EW: The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol 172: 973-981, 2006.
2. Thiery JP: Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2: 442-454, 2002.
3. Mani SA, Guo W, Liao MJ, et al: The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133: 704-715, 2008.
4. Morel AP, Lievre M, Thomas C, Hinkal G, Ansieau S and Puisieux A: Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS one 3: e2888, 2008.
5. Ansieau S, Bastid J, Doreau A, et al: Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence. Cancer Cell 14: 79-89, 2008.
6. Nieto MA: The snail superfamily of zinc-finger transcription factors. Nat Rev Mol Cell Biol 3: 155-166, 2002.
7. Peinado H, Olmeda D and Cano A: Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Nat Rev Cancer 7: 415-428, 2007.
8. Grimes HL, Chan TO, Zweidler-McKay PA, Tong B and Tsichlis PN: The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal. Mol Cell Biol 16: 6263-6272, 1996.
9. Nibu Y, Zhang H, Bajor E, Barolo S, Small S and Levine M: dCtBP mediates transcriptional repression by Knirps, Kruppel and Snail in the Drosophila embryo. EMBO J 17: 7009-7020, 1998.
10. Barrallo-Gimeno A and Nieto MA: Evolutionary history of the Snail/Scratch superfamily. Trends Genet (In press).
11. Barrallo-Gimeno A and Nieto MA: The Snail genes as inducers of cell movement and survival: implications in development and cancer. Development 132: 3151-3161, 2005.
12. Nieto MA, Sargent MG, Wilkinson DG and Cooke J: Control of cell behavior during vertebrate development by Slug, a zinc finger gene. Science 264: 835-839, 1994.
13. Carver EA, Jiang R, Lan Y, Oram KF and Gridley T: The mouse snail gene encodes a key regulator of the epithelialmesenchymal transition. Mol Cell Biol 21: 8184-8188, 2001.
14. Cobaleda C, Perez-Caro M, Vicente-Duenas C and Sanchez-Garcia I: Function of the zinc-finger transcription factor SNAI2 in cancer and development. Annu Rev Genet 41: 41-61, 2007.
15. Come C, Arnoux V, Bibeau F and Savagner P: Roles of the transcription factors snail and slug during mammary morphogenesis and breast carcinoma progression. J Mammary Gland Biol Neoplasia 9: 183-193, 2004.
16. Blanco MJ, Moreno-Bueno G, Sarrio D, Locascio A, Cano A, Palacios J and Nieto MA: Correlation of Snail expression with histological grade and lymph node status in breast carcinomas. Oncogene 21: 3241-3246, 2002.
17. Elloul S, Elstrand MB, Nesland JM, et al: Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma. Cancer 103: 1631-1643, 2005.
18. Rosivatz E, Becker I, Specht K, et al: Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer. Am J Pathol 161: 1881-1891, 2002.
19. Sugimachi K, Tanaka S, Kameyama T, et al: Transcriptional repressor snail and progression of human hepatocellular carcinoma. Clin Cancer Res 9: 2657-2664, 2003.
20. Miyoshi A, Kitajima Y, Kido S, Shimonishi T, Matsuyama S, Kitahara K and Miyazaki K: Snail accelerates cancer invasion by upregulating MMP expression and is associated with poor prognosis of hepatocellular carcinoma. Br J Cancer 92: 252-258, 2005.
21. Palmer HG, Larriba MJ, Garcia JM, et al: The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer. Nat Med 10: 917-919, 2004.
22. Saito T, Oda Y, Kawaguchi K, et al: E-cadherin mutation and Snail overexpression as alternative mechanisms of E-cadherin inactivation in synovial sarcoma. Oncogene 23: 8629-8638, 2004.
23. Poser I, Dominguez D, De Herreros AG, Varnai A, Buettner R and Bosserhoff AK: Loss of E-cadherin expression in melanoma cells involves up-regulation of the transcriptional repressor Snail. J Biol Chem 276: 24661-24666, 2001.
24. Olmeda D, Montes A, Moreno-Bueno G, Flores JM, Portillo F and Cano A: Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines. Oncogene 27: 4690-4701, 2008.
25. Olmeda D, Moreno-Bueno G, Flores JM, Fabra A, Portillo F and Cano A: SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells. Cancer Res 67: 11721-11731, 2007.
26. Moody SE, Perez D, Pan TC, et al: The transcriptional repressor Snail promotes mammary tumor recurrence. Cancer Cell 8: 197-209, 2005.
27. Vega S, Morales AV, Ocana OH, Valdes F, Fabregat I and Nieto MA: Snail blocks the cell cycle and confers resistance to cell death. Genes Dev 18: 1131-1143, 2004.
28. Wu Y, Deng J, Rychahou PG, Qiu S, Evers BM and Zhou BP: Stabilization of snail by NF-kappaB is required for inflammationinduced cell migration and invasion. Cancer Cell 15: 416-428, 2009.
29. Wu WS, Heinrichs S, Xu D, Garrison SP, Zambetti GP, Adams JM and Look AT: Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma. Cell 123: 641-653, 2005.
30. Roark M, Sturtevant MA, Emery J, Vaessin H, Grell E and Bier E: scratch, a pan-neural gene encoding a zinc finger protein related to snail, promotes neuronal development. Genes Dev 9: 2384-2398, 1995.
31. Nakakura EK, Watkins DN, Schuebel KE, Sriuranpong V, Borges MW, Nelkin BD and Ball DW: Mammalian scratch: a neural-specific Snail family transcriptional repressor. Proc Natl Acad Sci USA 98: 4010-4015, 2001.
32. Marin F and Nieto MA: The expression of Scratch genes in the developing and adult brain. Dev Dyn 235: 2586-2591, 2006.
33. Metzstein MM and Horvitz HR: The C. elegans cell death specification gene ces-1 encodes a snail family zinc finger protein. Mol Cell 4: 309-319, 1999.
34. Vandesompele J, De Preter K, Pattyn F, Poppe B, van Roy N, De Paepe A and Speleman F: Accurate normalization of realtime quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 18: 3, 2002.
35. Come C, Magnino F, Bibeau F, De Santa BP, Becker KF, Theillet C and Savagner P: Snail and slug play distinct roles during breast carcinoma progression. Clin Cancer Res 12: 5395-5402, 2006.
36. Uchikado Y, Natsugoe S, Okumura H, Setoyama T, Matsumoto M, Ishigami S and Aikou T: Slug expression in the E-cadherin preserved tumors is related to prognosis in patients with esophageal squamous cell carcinoma. Clin Cancer Res 11: 1174-1180, 2005.
37. Gupta PB, Kuperwasser C, Brunet JP, et al: The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nat Genet 37: 1047-1054, 2005.
38. Guy CT, Webster MA, Schaller M, Parsons TJ, Cardiff RD and Muller WJ: Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proc Natl Acad Sci USA 89: 10578-10582, 1992.