-
1
-
-
50349092250
-
LDL receptor-related protein 1: Unique tissue-specific functions revealed by selective gene knockout studies
-
Lillis AP, Van Duyn LB, Murphy-Ullrich JE, Strickland DK. LDL receptor-related protein 1: unique tissue-specific functions revealed by selective gene knockout studies. Physiol Rev 2008; 88: 887-918.
-
(2008)
Physiol Rev
, vol.88
, pp. 887-918
-
-
Lillis, A.P.1
Van Duyn, L.B.2
Murphy-Ullrich, J.E.3
Strickland, D.K.4
-
2
-
-
0037432766
-
LRP: Role in vascular wall integrity and protection from atherosclerosis
-
Boucher P, Gotthardt M, Li WP, et al. LRP: role in vascular wall integrity and protection from atherosclerosis. Science 2003; 300: 329-332.
-
(2003)
Science
, vol.300
, pp. 329-332
-
-
Boucher, P.1
Gotthardt, M.2
Li, W.P.3
-
3
-
-
10744231924
-
Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the lowdensity lipoprotein receptor-related protein
-
Zerbinatti CV, Wozniak DF, Cirrito J, et al. Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the lowdensity lipoprotein receptor-related protein. Proc Natl Acad Sci U S A 2004; 101: 1075-1080.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1075-1080
-
-
Zerbinatti, C.V.1
Wozniak, D.F.2
Cirrito, J.3
-
4
-
-
4744370253
-
Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4
-
Palsson-McDermott EM, O'Neill LA. Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4. Immunology 2004; 113: 153-162.
-
(2004)
Immunology
, vol.113
, pp. 153-162
-
-
Palsson-Mcdermott, E.M.1
O'neill, L.A.2
-
5
-
-
58749110564
-
Gamma-secretase limits the inflammatory response through the processing of LRP1
-
Zurhove K, Nakajima C, Herz J, et al. Gamma-secretase limits the inflammatory response through the processing of LRP1. Sci Signal 2008; 1: ra15.
-
(2008)
Sci Signal
, vol.1
, pp. 15
-
-
Zurhove, K.1
Nakajima, C.2
Herz, J.3
-
6
-
-
84867799461
-
Toll-like receptor signaling pathways in cardiovascular diseases: Challenges and opportunities
-
Moghimpour Bijani, F, Vallejo JG, Rezaei N. Toll-like receptor signaling pathways in cardiovascular diseases: challenges and opportunities. Int Rev Immunol 2012; 31: 379-395.
-
(2012)
Int Rev Immunol
, vol.31
, pp. 379-395
-
-
Moghimpour Bijani, F.1
Vallejo, J.G.2
Rezaei, N.3
-
7
-
-
35948958955
-
TLR4 enhances TGF-beta signaling and hepatic fibrosis
-
Seki E, De Minicis S, Osterreicher CH, et al. TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nat Med 2007; 13: 1324-1332.
-
(2007)
Nat Med
, vol.13
, pp. 1324-1332
-
-
Seki, E.1
De Minicis, S.2
Osterreicher, C.H.3
-
8
-
-
63249094657
-
Lipopolysaccharide alters the bloodbrain barrier transport of amyloid beta protein: A mechanism for inflammation in the progression of Alzheimer's disease
-
Jaeger LB, Dohgu S, Sultana R, et al. Lipopolysaccharide alters the bloodbrain barrier transport of amyloid beta protein: a mechanism for inflammation in the progression of Alzheimer's disease. Brain Behav Immun 2009; 23: 507-517.
-
(2009)
Brain Behav Immun
, vol.23
, pp. 507-517
-
-
Jaeger, L.B.1
Dohgu, S.2
Sultana, R.3
-
9
-
-
0033600274
-
Translating cell biology into therapeutic advances in Alzheimer's disease
-
Selkoe DJ. Translating cell biology into therapeutic advances in Alzheimer's disease. Nature 1999; 399: A23-A31.
-
(1999)
Nature
, vol.399
-
-
Selkoe, D.J.1
-
10
-
-
69949112770
-
Microglial low-density lipoprotein receptor-related protein 1 modulates c-Jun N-terminal kinase activation
-
Pocivavsek A, Mikhailenko I, Strickland DK, et al. Microglial low-density lipoprotein receptor-related protein 1 modulates c-Jun N-terminal kinase activation. J Neuroimmunol 2009; 214: 25-32.
-
(2009)
J Neuroimmunol
, vol.214
, pp. 25-32
-
-
Pocivavsek, A.1
Mikhailenko, I.2
Strickland, D.K.3
-
11
-
-
84863630839
-
Molecular mechanisms of the inhibitory effects of bovine lactoferrin on lipopolysaccharide-mediated osteoclastogenesis
-
Inubushi T, Kawazoe A, Miyauchi M, et al. Molecular mechanisms of the inhibitory effects of bovine lactoferrin on lipopolysaccharide-mediated osteoclastogenesis. J Biol Chem 2012; 287: 23527-23536.
-
(2012)
J Biol Chem
, vol.287
, pp. 23527-23536
-
-
Inubushi, T.1
Kawazoe, A.2
Miyauchi, M.3
-
12
-
-
77957866595
-
Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages
-
The investigators demonstrate that the LRP1 extracellular domain, which is shed from the plasma membrane in the course of inflammtory events, modulates the inflammatory process through the activation of p38 and JNK
-
Gorovoy M, Gaultier A, Campana WM, et al. Inflammatory mediators promote production of shed LRP1/CD91, which regulates cell signaling and cytokine expression by macrophages. J Leukoc Biol 2010; 88: 769-778. The investigators demonstrate that the LRP1 extracellular domain, which is shed from the plasma membrane in the course of inflammtory events, modulates the inflammatory process through the activation of p38 and JNK.
-
(2010)
J Leukoc Biol
, vol.88
, pp. 769-778
-
-
Gorovoy, M.1
Gaultier, A.2
Campana, W.M.3
-
13
-
-
45949089484
-
Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor
-
Gaultier A, Arandjelovic S, Niessen S, et al. Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor. Blood 2008; 111: 5316-5325.
-
(2008)
Blood
, vol.111
, pp. 5316-5325
-
-
Gaultier, A.1
Arandjelovic, S.2
Niessen, S.3
-
14
-
-
84866461090
-
Transforming growth factorbeta1 in inflammatory airway disease: A key for understanding inflammation and remodelling
-
Yang YC, Zhang N, Van Crombruggen K, et al. Transforming growth factorbeta1 in inflammatory airway disease: a key for understanding inflammation and remodelling. Allergy 2012; 67: 1193-1202.
-
(2012)
Allergy
, vol.67
, pp. 1193-1202
-
-
Yang, Y.C.1
Zhang, N.2
Van Crombruggen, K.3
-
15
-
-
44149093500
-
Transforming growth factor-beta1 in inflammatory airway disease: A key for understanding inflammation and remodelling
-
Boucher P, Li WP, Matz RL, et al. Transforming growth factor-beta1 in inflammatory airway disease: a key for understanding inflammation and remodelling. PLoS One 2007; 2: e448.
-
(2007)
PLoS One
, vol.2
-
-
Boucher, P.1
Li, W.P.2
Matz, R.L.3
-
16
-
-
0242582172
-
The cytoplasmic domain of the low density lipoprotein (LDL) receptor-related protein, but not that of the LDL receptor, triggers phagocytosis
-
Patel M, Morrow J, Maxfield FR, et al. The cytoplasmic domain of the low density lipoprotein (LDL) receptor-related protein, but not that of the LDL receptor, triggers phagocytosis. J Biol Chem 2003; 278: 44799-44807.
-
(2003)
J Biol Chem
, vol.278
, pp. 44799-44807
-
-
Patel, M.1
Morrow, J.2
Maxfield, F.R.3
-
17
-
-
0037023693
-
Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP)
-
Su HP, Nakada-Tsukui K, Tosello-Trampont AC, et al. Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP). J Biol Chem 2002; 277: 11772-11779.
-
(2002)
J Biol Chem
, vol.277
, pp. 11772-11779
-
-
Su, H.P.1
Nakada-Tsukui, K.2
Tosello-Trampont, A.C.3
-
18
-
-
0035903289
-
C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells
-
Ogden CA, deCathelineau A, Hoffmann PR, et al. C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells. J Exp Med 2001; 194: 781-795.
-
(2001)
J Exp Med
, vol.194
, pp. 781-795
-
-
Ogden, C.A.1
Decathelineau, A.2
Hoffmann, P.R.3
-
19
-
-
26844468253
-
Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte
-
Gardai SJ, McPhillips KA, Frasch SC, et al. Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte. Cell 2005; 123: 321-334.
-
(2005)
Cell
, vol.123
, pp. 321-334
-
-
Gardai, S.J.1
McPhillips, K.A.2
Frasch, S.C.3
-
20
-
-
84864804242
-
Primary phagocytosis of viable neurons by microglia activated with LPS or Abeta is dependent on calreticulin/LRP phagocytic signalling
-
Fricker M, Oliva-Martin MJ, Brown GC. Primary phagocytosis of viable neurons by microglia activated with LPS or Abeta is dependent on calreticulin/LRP phagocytic signalling. J Neuroinflammation 2009; 9: 196.
-
(2009)
J Neuroinflammation
, vol.9
, pp. 196
-
-
Fricker, M.1
Oliva-Martin, M.J.2
Brown, G.C.3
-
21
-
-
77950888338
-
Macrophage LRP-1 controls plaque cellularity by regulating efferocytosis and Akt activation
-
Yancey PG, Blakemore J, Ding L, et al. Macrophage LRP-1 controls plaque cellularity by regulating efferocytosis and Akt activation. Arterioscler Thromb Vasc Biol 2010; 30: 787-795.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 787-795
-
-
Yancey, P.G.1
Blakemore, J.2
Ding, L.3
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