Liver X receptor activation inhibits melanogenesis through the acceleration of ERK-mediated MITF degradation

Journal of Investigative Dermatology

Volumn 133, Issue 4, 2013, Pages 1063-1071

  Lee, Chang Seok ^a   Park, Miyoung ^a   Han, Jiwon ^a   Lee, Ji Hae ^a   Bae, Il Hong ^a   Choi, Hyunjung ^a   Son, Eui Dong ^a   Park, Young Ho ^a   Lim, Kyung Min ^a,b  

^a AmorePacific Corporation   (South Korea)

^b Ewha Womans University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

22 HYDROXYCHOLESTEROL; 3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; DOPACHROME TAUTOMERASE; LIVER X RECEPTOR; LIVER X RECEPTOR BETA; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; RAS PROTEIN; SMALL INTERFERING RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; EXPERIMENTAL GUINEA PIG; HUMAN; HUMAN CELL; IN VIVO STUDY; MELANOCYTE; MELANOGENESIS; MELANOMA; MELANOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

EID: 84875226505     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2012.409     Document Type: Article

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