Inhibition of choline acetyltransferase as a mechanism for cholinergic dysfunction induced by amyloid-β peptide oligomers

Journal of Biological Chemistry

Volumn 287, Issue 23, 2012, Pages 19377-19385

  Nunes Tavares, Nilson ^a   Santos, Luís Eduardo ^a   Stutz, Bernardo ^a   Brito Moreira, Jordano ^a   Klein, William L ^b   Ferreira, Sérgio T ^a   De Mello, Fernando G ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL TRANSFERASE; ALZHEIMER DISEASE; EXCITATORY SYNAPSIS; GLUTAMATE RECEPTOR; NANOMOLAR CONCENTRATION; NEURONAL DAMAGE; NEURONAL DYSFUNCTION; OXIDATIVE DAMAGE; PEPTIDE OLIGOMERS;

BROMINE COMPOUNDS; GLYCOPROTEINS; OLIGOMERS; PEPTIDES; POLYUNSATURATED FATTY ACIDS;

OSMIUM;

AMYLOID BETA PROTEIN; CHOLINE; CHOLINE ACETYLTRANSFERASE; GLUTAMATE RECEPTOR; INSULIN RECEPTOR; LACTATE DEHYDROGENASE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; OLIGOMER; POLYUNSATURATED FATTY ACID; REACTIVE OXYGEN METABOLITE; TETRAZOLIUM;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BINDING SITE; CELL CULTURE; CELL VIABILITY; CHOLINERGIC NERVE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA CELL; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ANTIOXIDANTS; AVIAN PROTEINS; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CHICKENS; CHOLINE O-ACETYLTRANSFERASE; EXCITATORY AMINO ACID ANTAGONISTS; NEURONS; OXIDATIVE STRESS;

EID: 84861727534     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.321448     Document Type: Article

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