Fatty Acid Ethyl Esters Induce Intestinal Epithelial Barrier Dysfunction via a Reactive Oxygen Species-Dependent Mechanism in a Three-Dimensional Cell Culture Model

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Elamin, Elhaseen ^a,b   Masclee, Ad ^a,b   Juuti Uusitalo, Kati ^a,d   van IJzendoorn, Sven ^a,c   Troost, Freddy ^a,b   Pieters, Harm Jan ^b   Dekker, Jan ^a,e   Jonkers, Daisy ^a,b  

^a TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^d TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^e WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; FATTY ACID ESTER; LACTATE DEHYDROGENASE; OCCLUDIN; OLEIC ACID ETHYL ESTER; PALMITIC ACID ETHYL ESTER; PROTEIN ZO1; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL CULTURE; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL VIABILITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME RELEASE; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; INTESTINE EPITHELIUM; INTESTINE MUCOSA PERMEABILITY; MEMBRANE DAMAGE; OXIDATIVE STRESS; PERMEABILITY BARRIER; PROTEIN LOCALIZATION;

ADENOSINE TRIPHOSPHATE; CACO-2 CELLS; CELL CULTURE TECHNIQUES; CELL MEMBRANE PERMEABILITY; ETHANOL; HUMANS; INTESTINAL MUCOSA; MODELS, BIOLOGICAL; OCCLUDIN; OLEIC ACIDS; OXIDATIVE STRESS; PALMITIC ACIDS; REACTIVE OXYGEN SPECIES; STILBENES; TIGHT JUNCTIONS; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84875114040     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058561     Document Type: Article

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