Increased placental phospholipid levels in pre-eclamptic pregnancies

International Journal of Molecular Sciences

Volumn 14, Issue 2, 2013, Pages 3487-3499

  Huang, Xiao ^a   Jain, Arjun ^a   Baumann, Marc ^a   Körner, Meike ^a   Surbek, Daniel ^a   Bütikofer, Peter ^a   Albrecht, Christiane ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

Phospholipids; Placenta; Pre eclampsia

Indexed keywords

CHOLESTEROL; LIPID PEROXIDE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLSERINE; PHOSPHOLIPID; SPHINGOMYELIN;

ADULT; AGE; ARTICLE; BIRTH WEIGHT; BODY MASS; CLINICAL ARTICLE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FEMALE; FETUS DEATH; GESTATIONAL AGE; HUMAN; INTRAUTERINE GROWTH RETARDATION; LIPID BILAYER; LIPID METABOLISM; LIPID TRANSPORT; PARITY; PLACENTA; PLACENTA DISORDER; PLACENTA WEIGHT; PREECLAMPSIA; PROTEIN EXPRESSION; PROTEIN LIPID INTERACTION; PROTEIN LOCALIZATION; PROTEINURIA; SYNCYTIOTROPHOBLAST; SYSTOLIC BLOOD PRESSURE; THIN LAYER CHROMATOGRAPHY;

EID: 84875107334     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms14023487     Document Type: Article

References (52)

1. Brizzi, P.; Tonolo, G.; Esposito, F.; Puddu, L.; Dessole, S.; Maioli, M.; Milia, S. Lipoprotein metabolism during normal pregnancy. Am. J. Obstet. Gynecol. 1999, 181, 430-434.
2. Enquobahrie, D.A.; Williams, M.A.; Butler, C.L.; Frederick, I.O.; Miller, R.S.; Luthy, D.A. Maternal plasma lipid concentrations in early pregnancy and risk of preeclampsia. Am. J. Hypertens. 2004, 17, 574-581.
3. Lippi, G.; Albiero, A.; Montagnana, M.; Salvagno, G.L.; Scevarolli, S.; Franchi, M.; Guidi, G.C. Lipid and lipoprotein profile in physiological pregnancy. Clin. Lab. 2007, 53, 173-177.
4. Ekhator, C.N.; Ebomoyi, M.I. Blood glucose and serum lipid profiles during pregnancy. Afr. J. Diabetes Med. 2012, 20, 1-4.
5. Vrijkotte, T.G.; Krukziener, N.; Hutten, B.A.; Vollebregt, K.C.; van Eijsden, M.; Twickler, M.B. Maternal lipid profile during early pregnancy and pregnancy complications and outcomes: The ABCD study. J. Clin. Endocrinol. Metab. 2012, 97, 3917-3925.
6. Hubel, C.A. Oxidative stress in the pathogenesis of preeclampsia. Proc. Soc. Exp. Biol. Med. 1999, 222, 222-235.
7. Roberts, J.M.; Hubel, C.A. Is oxidative stress the link in the two-stage model of pre-eclampsia? Lancet 1999, 354, 788-789.
8. Lima, V.J.; Andrade, C.R.; Ruschi, G.E.; Sass, N. Serum lipid levels in pregnancies complicated by preeclampsia. Sao Paulo Med. J. 2011, 129, 73-76.
9. Evrüke, I.C.; Demir, S.C.; Ürünsak, I.F.; Özgünen, F.T.; Kadayifci, O. Comparison of lipid profiles in normal and hypertensive pregnant women. Ann. Saudi Med. 2004, 24, 382-385.
10. Herrera, E. Lipid metabolism in pregnancy and its consequences in the fetus and newborn. Endocrine 2002, 19, 43-55.
11. Elmes, M.; Tew, P.; Cheng, Z.; Kirkup, S.E.; Abayasekara, D.R.; Calder, P.C.; Hanson, M.A.; Wathes, D.C.; Burdge, G.C. The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins. Biochim. Biophys. Acta 2004, 1686, 139-147.
12. Sen, A.; Ghosh, P.K.; Mukherjea, M. Changes in lipid composition and fluidity of human placental basal membrane and modulation of bilayer protein functions with progress of gestation. Mol. Cell. Biochem. 1998, 187, 183-190.
13. Rebourcet, R.; de Ceuninck, F.; Deborde, S.; Willeput, J.; Ferré, F. Differential distribution of binding sites for 125I-insulin-like growth factor II on trophoblast membranes of human term placenta. Biol. Reprod. 1998, 58, 37-44.
14. North, P.; Fleischer, S. Alteration of synaptic membrane cholesterol/phospholipid ratio using a lipid transfer protein. Effect on gamma-aminobutyric acid uptake. J. Biol. Chem. 1983, 258, 1242-1253.
15. Shinitzky, M.; Inbar, M. Difference in microviscosity induced by different cholesterol levels in the surface membrane lipid layer of normal lymphocytes and malignant lymphoma cells. J. Mol. Biol. 1974, 85, 603-615.
16. Ohyashiki, T.; Sakata, N.; Matsui, K. A decrease of lipid fluidity of the porcine intestinal brush-border membranes by treatment with malondialdehyde. J. Biochem. 1992, 111, 419-423.
17. Cogan, U.; Shinitzky, M.; Weber, G.; Nishida, T. Microviscosity and order in the hydrocarbon region of phospholipid and phospholipid-cholesterol dispersions determined with fluorescent probes. Biochemistry 1973, 12, 521-528.
18. Staff, A.C.; Ranheim, T.; Khoury, J.; Henriksen, T. Increased contents of phospholipids, cholesterol, and lipid peroxides in decidua basalis in women with preeclampsia. Am. J. Obstet. Gynecol. 1999, 180, 587-592.
19. Bayon, Y.; Croset, M.; Chirouze, V.; Tayot, J.L.; Lagarde, M. Phospholipid molecular species from human placenta lipids. Lipids 1993, 28, 631-636.
20. Singh, E.J.; Swartwout, J.R. The phospholipid composition of human placenta, endometrium and amniotic fluid: A comparative study. Lipids 1972, 7, 26-29.
21. Romero, R.; Mazor, M.; Munoz, H.; Gomez, R.; Galasso, M.; Sherer, D.M. The preterm labor syndrome. Ann. N. Y. Acad. Sci. 1994, 734, 414-429.
22. Lockwood, C.J.; Kuczynski, E. Markers of risk for preterm delivery. J. Perinat. Med. 1999, 27, 5-20.
23. Cindrova-Davies, T.; Yung, H.W.; Johns, J.; Spasic-Boskovic, O.; Korolchuk, S.; Jauniaux, E.; Burton, G.J.; Charnock-Jones, D.S. Oxidative stress, gene expression, and protein changes induced in the human placenta during labor. Am. J. Pathol. 2007, 171, 1168-1179.
24. Harbison, J.A.; Walsh, S.; Kenny, R.A. Hypertension and daytime hypotension found on ambulatory blood pressure is associated with fatigue following stroke and TIA. QJM 2009, 102, 109-115.
25. Lugo, G.; Cassady, G. Intrauterine growth retardation. Clinicopathologic findings in 233 consecutive infants. Am. J. Obstet. Gynecol. 1971, 109, 615-622.
26. Olsson, N.U.; Salem, N., Jr. Molecular species analysis of phospholipids. J. Chromatogr. B Biomed. Sci. Appl. 1997, 692, 245-256.
27. Van Meer, G.; Voelker, D.R.; Feigenson, G.W. Membrane lipids: Where they are and how they behave. Nat. Rev. Mol. Cell Biol. 2008, 9, 112-124.
28. McCoy, S.; Baldwin, K. Pharmacotherapeutic options for the treatment of preeclampsia. Am. J. Health-Syst. Pharm. 2009, 66, 337-344.
29. Gilbert, J.S.; Ryan, M.J.; LaMarca, B.B.; Sedeek, M.; Murphy, S.R.; Granger, J.P. Pathophysiology of hypertension during preeclampsia linking placental ischemia with endothelial dysfunction. Hypertension 2001, 38, 718-722.
30. Sikkema, J.M.; Franx, A.; Bruinse, H.W.; van der Wijk, N.G.; de Valk, H.W.; Nikkels, P.G. Placental pathology in early onset pre-eclampsia and intra-uterine growth restriction in women with and without thrombophilia. Placenta 2002, 23, 337-342.
31. Hung, T.H.; Burton, G.J. Hypoxia and reoxygenation: A possible mechanism for placental oxidative stress in preeclampsia. Taiwan J. Obstet. Gynecol. 2006, 45, 189-200.
32. Jain, A. Endothelin-1: A key pathological factor in pre-eclampsia? Reprod. Biomed. Online 2012, 25, 443-449.
33. Jain, A.; Olovsson, M.; Burton, G.J.; Yung, H.W. Endothelin-1 induces endoplasmic reticulum stress by activating the PLC-IP(3) pathway: Implications for placental pathophysiology in preeclampsia. Am. J. Pathol. 2012, 180, 2309-2320.
34. Sen, C.K.; Packer, L. Antioxidant and redox regulation of gene transcription. FASEB J. 1996, 10, 709-720.
35. Scholler, M.; Wadsack, C.; Metso, J.; Chirackal Manavalan, A.P.; Sreckovic, I.; Schweinzer, C.; Hiden, U.; Jauhiainen, M.; Desoye, G.; Panzenboeck, U. Phospholipid transfer protein is differentially expressed in human arterial and venous placental endothelial cells and enhances cholesterol efflux to fetal HDL. J. Clin. Endocrinol. Metab. 2012, 97, 2466-2474.
36. Napoli, C.; D'Armiento, F.P.; Mancini, F.P.; Postiglione, A.; Witztum, J.L.; Palumbo, G.; Palinski, W. Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions. J. Clin. Invest. 1997, 100, 2680-2690.
37. Tranquilli, A.L.; Saccucci, F.; Giannubilo, S.R.; Cecati, M.; Nocchi, L.; Lorenzi, S.; Emanuelli, M. Unexplained fetal loss: The fetal side of thrombophilia. Fertil. Steril. 2010, 94, 378-380.
38. Nesheim, M.E.; Taswell, J.B.; Mann, K.G. The contribution of bovine Factor V and Factor Va to the activity of prothrombinase. J. Biol. Chem. 1979, 254, 10952-10962.
39. Davie, E.W.; Fujikawa, K. Basic mechanisms in blood coagulation. Annu. Rev. Biochem. 1975, 44, 799-829.
40. Omatsu, K.; Kobayashi, T.; Murakami, Y.; Suzuki, M.; Ohashi, R.; Sugimura, M.; Kanayama, N. Phosphatidylserine/phosphatidylcholine microvesicles can induce preeclampsia-like changes in pregnant mice. Semin. Throm. Hemost. 2005, 31, 314-320.
41. Zhang, Y.; Hua, Z.; Zhang, K.; Meng, K.; Hu, Y. Therapeutic effects of anticoagulant agents on preeclampsia in a murine model induced by phosphatidylserine/phosphatidylcholine microvesicles. Placenta 2009, 30, 1065-1070.
42. Myatt, L. Review: Reactive oxygen and nitrogen species and functional adaptation of the placenta. Placenta 2010, 31, S66-S69.
43. Krishna, U.; Bhalerao, S. Placental insufficiency and fetal growth restriction. J. Obstet. Gynaecol. India 2011, 61, 505-511.
44. Langmann, T.; Klucken, J.; Reil, M.; Liebisch, G.; Luciani, M.F.; Chimini, G.; Kaminski, W.E.; Schmitz, G. Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): Evidence for sterol-dependent regulation in macrophages. Biochem. Biophys. Res. Commun. 1999, 257, 29-33.
45. Oram, J.F. ATP-binding cassette transporter A1 and cholesterol trafficking. Curr. Opin. Lipidol. 2002, 13, 373-381.
46. Albrecht, C.; Nikitina, L.; Wenger, F.; Baumann, M.; Surbek, D.; Körner, M. Localisation of ABCA1 in first trimester and term placental tissues. Placenta 2010, 31, 741-742.
47. Nikitina, L.; Wenger, F.; Baumann, M.; Surbek, D.; Körner, M.; Albrecht, C. Expression and localization pattern of ABCA1 in diverse human placental primary cells and tissues. Placenta 2011, 32, 420-430.
48. Paul, V.; Meyer, H.H.; Leidl, K.; Soumian, S.; Albrecht, C. A novel enzyme immunoassay specific for ABCA1 protein quantification in human tissues and cells. J. Lipid Res. 2008, 49, 2259-2267.
49. Aye, I.L.; Waddell, B.J.; Mark, P.J.; Keelan, J.A. Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity. Biochim. Biophys. Acta 2010, 1801, 1013-1024.
50. Körner, M.; Wenger, F.; Nikitina, L.; Baumann, M.; Surbek, D. l Albrecht, C. PP141. The lipid transporters ABCA1 and ABCG1 are differentially expressed in preeclamptic and IUGR placentas. Pregnancy Hypertens. 2012, 2, 315-316.
51. Bligh, E.G.; Dyer, W.J. A rapid method of total lipid extraction and purification. Can. J. Biochem. Physiol. 1959, 37, 911-917.
52. Signorell, A.; Rauch, M.; Jelk, J.; Ferguson, M.A.; Bütikofer, P. Phosphatidylethanolamine in Trypanosoma brucei is organized in two separate pools and is synthesized exclusively by the Kennedy pathway. J. Biol. Chem. 2008, 283, 23636-23644.