Endothelin-1 induces endoplasmic reticulum stress by activating the PLC-IP 3 pathway: Implications for placental pathophysiology in preeclampsia

American Journal of Pathology

Volumn 180, Issue 6, 2012, Pages 2309-2320

  Jain, Arjun ^a   Olovsson, Matts ^b   Burton, Graham J ^a   Yung, Hong Wa ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CALCIUM ION; ENDOTHELIN 1; ENDOTHELIN B RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; NEUTRALIZING ANTIBODY; PHOSPHOLIPASE C GAMMA1; SMALL INTERFERING RNA; XESTOSPONGIN C;

ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CARCINOMA CELL; CELL ACTIVATION; CHORIOCARCINOMA; COMPARATIVE STUDY; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOXIA; IMMUNOREACTIVITY; IN VITRO STUDY; PATHOPHYSIOLOGY; PHOSPHOACTIVATION; PLACENTA; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PROCESSING; REOXYGENATION; SIGNAL TRANSDUCTION; STRESS; SYNCYTIOTROPHOBLAST;

DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIN-1; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; PHOSPHORYLATION; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TISSUE CULTURE TECHNIQUES; TROPHOBLASTS; TUMOR CELLS, CULTURED; TYPE C PHOSPHOLIPASES;

EID: 84861651056     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.03.005     Document Type: Article

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