Cyclosporine A Impairs Nucleotide Binding Oligomerization Domain (Nod1)-Mediated Innate Antibacterial Renal Defenses in Mice and Human Transplant Recipients

PLoS Pathogens

Volumn 9, Issue 1, 2013, Pages

  Tourneur, Emilie ^a   Ben Mkaddem, Sanae ^b,c   Chassin, Cécilia ^b,c   Bens, Marcelle ^a   Goujon, Jean Michel ^d,e   Charles, Nicolas ^b,c   Pellefigues, Christophe ^b,c   Aloulou, Meryem ^b,c   Hertig, Alexandre ^f,g   Monteiro, Renato C ^b,c   Girardin, Stephen E ^h   Philpott, Dana J ⁱ   Rondeau, Eric ^f,g   Elbim, Carole ^b   Werts, Catherine ^j   Vandewalle, Alain ^a  

^a CENTRE DE RECHERCHE BIOMÉDICALE BICHAT BEAUJON CRB3   (France)

^b INSERM   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d UNIVERSITÉ DE POITIERS   (France)

^e Service d'Anatomie et de Cytologie Pathologiques   (France)

^f HÔPITAL TENON   (France)

^g SORBONNE UNIVERSITÉ   (France)

^h UNIVERSITY OF TORONTO   (Canada)

ⁱ UNIVERSITY OF TORONTO   (Canada)

^j INSTITUT PASTEUR   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; CYCLOSPORIN; NUCLEAR FACTOR; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN PROTEIN; TOLL LIKE RECEPTOR 4;

ACUTE PYELONEPHRITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL LOAD; BACTERICIDAL ACTIVITY; CELL POPULATION; CONTROLLED STUDY; DENDRITIC CELL; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GRAFT RECIPIENT; HOST RESISTANCE; HUMAN; IMMUNE RESPONSE; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; MACROPHAGE; NEUTROPHIL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHAGOCYTOSIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UROPATHOGENIC ESCHERICHIA COLI; WESTERN BLOTTING;

ACUTE DISEASE; ANIMALS; BONE MARROW CELLS; CELL MOVEMENT; CHEMOKINES; CYCLOSPORINE; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; FEMALE; GENE SILENCING; HUMANS; IMMUNITY, INNATE; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; KIDNEY TRANSPLANTATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHILS; NFATC TRANSCRIPTION FACTORS; NOD1 SIGNALING ADAPTOR PROTEIN; ORGAN CULTURE TECHNIQUES; PHAGOCYTOSIS; PYELONEPHRITIS;

EID: 84875060230     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003152     Document Type: Article

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