-
1
-
-
33646942669
-
Reflections on the 'discovery' of the antimalarial qinghao
-
Hsu E, (2006) Reflections on the 'discovery' of the antimalarial qinghao. British J Clin Pharmaco 61: 666-670.
-
(2006)
British J Clin Pharmaco
, vol.61
, pp. 666-670
-
-
Hsu, E.1
-
2
-
-
80052937334
-
Artemisinin: Discovery from the Chinese Herbal Garden
-
Miller LH, Su XZ, (2011) Artemisinin: Discovery from the Chinese Herbal Garden. Cell 146: 855-858.
-
(2011)
Cell
, vol.146
, pp. 855-858
-
-
Miller, L.H.1
Su, X.Z.2
-
3
-
-
42349104331
-
Qinghaosu (Artemisinin): The price of success
-
White NJ, (2008) Qinghaosu (Artemisinin): The price of success. Science 320: 330-334.
-
(2008)
Science
, vol.320
, pp. 330-334
-
-
White, N.J.1
-
4
-
-
78449267241
-
Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial
-
Dondorp AM, Fanello CI, Hendriksen ICE, Gomes E, Seni A, et al. (2010) Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial. Lancet 376: 1647-1657.
-
(2010)
Lancet
, vol.376
, pp. 1647-1657
-
-
Dondorp, A.M.1
Fanello, C.I.2
Hendriksen, I.C.E.3
Gomes, E.4
Seni, A.5
-
5
-
-
0442307497
-
Antimalarial drug toxicity - A review
-
Taylor WRJ, White NJ, (2004) Antimalarial drug toxicity- A review. Drug Safety 27: 25-61.
-
(2004)
Drug Safety
, vol.27
, pp. 25-61
-
-
Taylor, W.R.J.1
White, N.J.2
-
6
-
-
58149465600
-
Does Artesunate Prolong the Electrocardiograph QT Interval in Patients with Severe Malaria?
-
Maude RJ, Plewes K, Faiz MA, Hanson J, Charunwatthana P, et al. (2009) Does Artesunate Prolong the Electrocardiograph QT Interval in Patients with Severe Malaria? Am J Trop Med Hyg 80: 126-132.
-
(2009)
Am J Trop Med Hyg
, vol.80
, pp. 126-132
-
-
Maude, R.J.1
Plewes, K.2
Faiz, M.A.3
Hanson, J.4
Charunwatthana, P.5
-
7
-
-
34249097684
-
Malaria-infected mice are cured by a single dose of novel artemisinin derivatives
-
Posner GH, Paik I-H, Chang W, Borstnik K, Sinishtaj S, et al. (2007) Malaria-infected mice are cured by a single dose of novel artemisinin derivatives. J Med Chem 50: 2516-2519.
-
(2007)
J Med Chem
, vol.50
, pp. 2516-2519
-
-
Posner, G.H.1
Paik, I.-H.2
Chang, W.3
Borstnik, K.4
Sinishtaj, S.5
-
9
-
-
78649251920
-
Heme as Trigger and Target for Trioxane-Containing Antimalarial Drugs
-
Meunier B, Robert A, (2010) Heme as Trigger and Target for Trioxane-Containing Antimalarial Drugs. Acc Chem Res 43: 1444-1451.
-
(2010)
Acc Chem Res
, vol.43
, pp. 1444-1451
-
-
Meunier, B.1
Robert, A.2
-
10
-
-
57349092438
-
Interplay Between Malaria, Crystalline Hemozoin Formation, and Antimalarial Drug Action and Design
-
Weissbuch I, Leiserowitz L, (2008) Interplay Between Malaria, Crystalline Hemozoin Formation, and Antimalarial Drug Action and Design. Chem Rev 108: 4899-4914.
-
(2008)
Chem Rev
, vol.108
, pp. 4899-4914
-
-
Weissbuch, I.1
Leiserowitz, L.2
-
11
-
-
0019794184
-
Receptor-Mediated Endocytosis of Transferrin in Developmentally Totipotent Mouse Treatocarcinoma Stem-Cells
-
Karin M, Mintz B, (1981) Receptor-Mediated Endocytosis of Transferrin in Developmentally Totipotent Mouse Treatocarcinoma Stem-Cells. J Biol Chem 256: 3245-3252.
-
(1981)
J Biol Chem
, vol.256
, pp. 3245-3252
-
-
Karin, M.1
Mintz, B.2
-
12
-
-
0029744951
-
Transferrin Receptor Expression by Blast Cells in Acute Lymphoblastic Leukemia Correlates with White Cell Count and Immunophenotype
-
Das-Gupta A, Patil J, Shah V, (1996) Transferrin Receptor Expression by Blast Cells in Acute Lymphoblastic Leukemia Correlates with White Cell Count and Immunophenotype. Indian J Med Res 104: 226-233.
-
(1996)
Indian J Med Res
, vol.104
, pp. 226-233
-
-
Das-Gupta, A.1
Patil, J.2
Shah, V.3
-
13
-
-
0022383509
-
TRANSFERRIN RECEPTOR - ITS BIOLOGICAL SIGNIFICANCE
-
May WS, Cuatrecasas P, (1985) TRANSFERRIN RECEPTOR- ITS BIOLOGICAL SIGNIFICANCE. J Membrane Biol 88: 205-215.
-
(1985)
J Membrane Biol
, vol.88
, pp. 205-215
-
-
May, W.S.1
Cuatrecasas, P.2
-
14
-
-
0027417773
-
Serum transferrin receptor level is not altered in invasive adenocarcinoma of the breast
-
Raaf H, Jacobsen D, Savon S, Green R, (1993) Serum transferrin receptor level is not altered in invasive adenocarcinoma of the breast. Am J Clin Pathol 99: 232-237.
-
(1993)
Am J Clin Pathol
, vol.99
, pp. 232-237
-
-
Raaf, H.1
Jacobsen, D.2
Savon, S.3
Green, R.4
-
16
-
-
75749141972
-
Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents
-
Chaturvedi D, Goswami A, Saikia PP, Barua NC, Rao PG, (2010) Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents. Chem Soc Rev 39: 435-454.
-
(2010)
Chem Soc Rev
, vol.39
, pp. 435-454
-
-
Chaturvedi, D.1
Goswami, A.2
Saikia, P.P.3
Barua, N.C.4
Rao, P.G.5
-
17
-
-
79953779279
-
In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents
-
Gravett AM, Liu WM, Krishna S, Chan WC, Haynes RK, et al. (2011) In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents. Cancer Chemoth Pharm 67: 569-577.
-
(2011)
Cancer Chemoth Pharm
, vol.67
, pp. 569-577
-
-
Gravett, A.M.1
Liu, W.M.2
Krishna, S.3
Chan, W.C.4
Haynes, R.K.5
-
18
-
-
80052337277
-
An Artemisinin-Derived Dimer Has Highly Potent Anti-Cytomegalovirus (CMV) and Anti-Cancer Activities
-
He R, Mott BT, Rosenthal AS, Genna DT, Posner GH, et al. (2011) An Artemisinin-Derived Dimer Has Highly Potent Anti-Cytomegalovirus (CMV) and Anti-Cancer Activities. Plos One 6.
-
(2011)
Plos One
, vol.6
-
-
He, R.1
Mott, B.T.2
Rosenthal, A.S.3
Genna, D.T.4
Posner, G.H.5
-
19
-
-
0037186497
-
Mechanism-based design of parasite-targeted artemisinin derivatives: Synthesis and antimalarial activity of new diamine containing analogues
-
Hindley S, Ward SA, Storr RC, Searle NL, Bray PG, et al. (2002) Mechanism-based design of parasite-targeted artemisinin derivatives: Synthesis and antimalarial activity of new diamine containing analogues. J Med Chem 45: 1052-1063.
-
(2002)
J Med Chem
, vol.45
, pp. 1052-1063
-
-
Hindley, S.1
Ward, S.A.2
Storr, R.C.3
Searle, N.L.4
Bray, P.G.5
-
20
-
-
79953707600
-
Anti-tumor effects of dihydroartemisinin on human osteosarcoma
-
Ji Y, Zhang YC, Pei LB, Shi LL, Yan JL, et al. (2011) Anti-tumor effects of dihydroartemisinin on human osteosarcoma. Mol Cell Biochem 351: 99-108.
-
(2011)
Mol Cell Biochem
, vol.351
, pp. 99-108
-
-
Ji, Y.1
Zhang, Y.C.2
Pei, L.B.3
Shi, L.L.4
Yan, J.L.5
-
21
-
-
0037435055
-
Antitumor activity of novel deoxoartemisinin monomers, dimers, and trimer
-
Jung M, Lee S, Ham J, Lee K, Kim H, et al. (2003) Antitumor activity of novel deoxoartemisinin monomers, dimers, and trimer. J Med Chem 46: 987-994.
-
(2003)
J Med Chem
, vol.46
, pp. 987-994
-
-
Jung, M.1
Lee, S.2
Ham, J.3
Lee, K.4
Kim, H.5
-
22
-
-
68249142819
-
Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction
-
Stockwin LH, Han BN, Yu SX, Hollingshead MG, ElSohly MA, et al. (2009) Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction. Int J Cancer 125: 1266-1275.
-
(2009)
Int J Cancer
, vol.125
, pp. 1266-1275
-
-
Stockwin, L.H.1
Han, B.N.2
Yu, S.X.3
Hollingshead, M.G.4
ElSohly, M.A.5
-
23
-
-
78651267641
-
Artemisinin inhibits in vitro and in vivo invasion and metastasis of human hepatocellular carcinoma cells
-
Tan WF, Shen F, Luo XJ, Su CQ, Qiu ZQ, et al. (2011) Artemisinin inhibits in vitro and in vivo invasion and metastasis of human hepatocellular carcinoma cells. Phytomedicine 18: 158-162.
-
(2011)
Phytomedicine
, vol.18
, pp. 158-162
-
-
Tan, W.F.1
Shen, F.2
Luo, X.J.3
Su, C.Q.4
Qiu, Z.Q.5
-
24
-
-
70349226926
-
Design, Synthesis and Antiproliferative Activities of Artemisinin Derivatives Containing a Substituted Piperazine
-
Yang XL, Liu D, Wang W, Qu L, Jing YK, et al. (2009) Design, Synthesis and Antiproliferative Activities of Artemisinin Derivatives Containing a Substituted Piperazine. Letters in Drug Design & Discovery 6: 595-598.
-
(2009)
Letters in Drug Design & Discovery
, vol.6
, pp. 595-598
-
-
Yang, X.L.1
Liu, D.2
Wang, W.3
Qu, L.4
Jing, Y.K.5
-
25
-
-
0035194318
-
Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells
-
Singh NP, Lai H, (2001) Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells. Life Sci 70: 49-56.
-
(2001)
Life Sci
, vol.70
, pp. 49-56
-
-
Singh, N.P.1
Lai, H.2
-
26
-
-
0036132144
-
New chemical and biological aspects of artemisinin-derived trioxane dimers
-
Posner GH, Northrop J, Paik IH, Borstnik K, Dolan P, et al. (2002) New chemical and biological aspects of artemisinin-derived trioxane dimers. Bioorgan Med Chem 10: 227-232.
-
(2002)
Bioorgan Med Chem
, vol.10
, pp. 227-232
-
-
Posner, G.H.1
Northrop, J.2
Paik, I.H.3
Borstnik, K.4
Dolan, P.5
-
27
-
-
0037435053
-
Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy
-
Posner GH, Paik IH, Sur S, McRiner AJ, Borstnik K, et al. (2003) Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy. J Med Chem 46: 1060-1065.
-
(2003)
J Med Chem
, vol.46
, pp. 1060-1065
-
-
Posner, G.H.1
Paik, I.H.2
Sur, S.3
McRiner, A.J.4
Borstnik, K.5
-
28
-
-
1242296302
-
Anticancer and antimalarial efficacy and safety of artemisinin-derived trioxane dimers in rodents
-
Posner GH, McRiner AJ, Paik IH, Sur S, Borstnik K, et al. (2004) Anticancer and antimalarial efficacy and safety of artemisinin-derived trioxane dimers in rodents. J Med Chem 47: 1299-1301.
-
(2004)
J Med Chem
, vol.47
, pp. 1299-1301
-
-
Posner, G.H.1
McRiner, A.J.2
Paik, I.H.3
Sur, S.4
Borstnik, K.5
-
29
-
-
58149316208
-
Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis
-
Nakase I, Gallis B, Takatani-Nakase T, Oh S, Lacoste E, et al. (2009) Transferrin receptor-dependent cytotoxicity of artemisinin-transferrin conjugates on prostate cancer cells and induction of apoptosis. Cancer Lett 274: 290-298.
-
(2009)
Cancer Lett
, vol.274
, pp. 290-298
-
-
Nakase, I.1
Gallis, B.2
Takatani-Nakase, T.3
Oh, S.4
Lacoste, E.5
-
30
-
-
77949356490
-
Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells
-
Morrissey C, Gallis B, Solazzi JW, Kim BJ, Gulati R, et al. (2010) Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells. Anticancer Drugs 21: 423-432.
-
(2010)
Anticancer Drugs
, vol.21
, pp. 423-432
-
-
Morrissey, C.1
Gallis, B.2
Solazzi, J.W.3
Kim, B.J.4
Gulati, R.5
-
31
-
-
77952795743
-
Anticancer activities of artemisinin and its bioactive derivatives
-
Firestone GL, Sundar SN, (2009) Anticancer activities of artemisinin and its bioactive derivatives. Expert Rev Mol Med 11.
-
(2009)
Expert Rev Mol Med
, vol.11
-
-
Firestone, G.L.1
Sundar, S.N.2
-
32
-
-
79955820798
-
Interruption of the MEK/ERK signaling cascade promotes dihydroartemisinin-induced apoptosis in vitro and in vivo
-
Gao N, Budhraja A, Cheng S, Liu EH, Huang C, et al. (2011) Interruption of the MEK/ERK signaling cascade promotes dihydroartemisinin-induced apoptosis in vitro and in vivo. Apoptosis 16: 511-523.
-
(2011)
Apoptosis
, vol.16
, pp. 511-523
-
-
Gao, N.1
Budhraja, A.2
Cheng, S.3
Liu, E.H.4
Huang, C.5
-
33
-
-
58549110422
-
Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity
-
Galal AM, Gul W, Slade D, Ross SA, Feng S, et al. (2009) Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity. Bioorgan Med Chem 17: 741-751.
-
(2009)
Bioorgan Med Chem
, vol.17
, pp. 741-751
-
-
Galal, A.M.1
Gul, W.2
Slade, D.3
Ross, S.A.4
Feng, S.5
-
34
-
-
84855174165
-
Effects of Artemisinin Dimers on Rat Breast Cancer Cells In Vitro and In Vivo
-
Singh NP, Lai HC, Park JS, Gerhardt TE, Kim BJ, et al. (2011) Effects of Artemisinin Dimers on Rat Breast Cancer Cells In Vitro and In Vivo. Anticancer Res 31: 4111-4114.
-
(2011)
Anticancer Res
, vol.31
, pp. 4111-4114
-
-
Singh, N.P.1
Lai, H.C.2
Park, J.S.3
Gerhardt, T.E.4
Kim, B.J.5
-
35
-
-
0029891746
-
Transport of artemisinin and sodium artesunate in Caco-2 intestinal epithelial cells
-
Augustijns P, Dhulst A, VanDaele J, Kinget R, (1996) Transport of artemisinin and sodium artesunate in Caco-2 intestinal epithelial cells. J Pharm Sci 85: 577-579.
-
(1996)
J Pharm Sci
, vol.85
, pp. 577-579
-
-
Augustijns, P.1
Dhulst, A.2
VanDaele, J.3
Kinget, R.4
-
36
-
-
80052673399
-
Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration
-
Morris CA, Duparc S, Borghini-Fuhrer I, Jung D, Shin CS, et al. (2011) Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration. Malaria J 10: 17.
-
(2011)
Malaria J
, vol.10
, pp. 17
-
-
Morris, C.A.1
Duparc, S.2
Borghini-Fuhrer, I.3
Jung, D.4
Shin, C.S.5
-
37
-
-
0025760693
-
NANOPARTICLE-BASED DRUG DELIVERY SYSTEMS
-
Kreuter J, (1991) NANOPARTICLE-BASED DRUG DELIVERY SYSTEMS. Journal of Control Release 16: 169-176.
-
(1991)
Journal of Control Release
, vol.16
, pp. 169-176
-
-
Kreuter, J.1
-
38
-
-
0003742254
-
-
New York, USA: Marcel Dekker, Inc
-
(1999) Liposomes: Rational Design. New York, USA: Marcel Dekker, Inc. 451 p.
-
(1999)
Liposomes: Rational Design
, pp. 451
-
-
-
39
-
-
1642362625
-
Drug delivery systems: Entering the mainstream
-
Allen TM, Cullis PR, (2004) Drug delivery systems: Entering the mainstream. Science 303: 1818-1822.
-
(2004)
Science
, vol.303
, pp. 1818-1822
-
-
Allen, T.M.1
Cullis, P.R.2
-
40
-
-
0003865155
-
-
The Netherlands: Elsevier Science B.V
-
(1998) Medical Applications of Liposomes. The Netherlands: Elsevier Science B.V. 779 p.
-
(1998)
Medical Applications of Liposomes
, pp. 779
-
-
-
41
-
-
79960825218
-
Imaging pH and metastasis
-
Hashim AI, Zhang XM, Wojtkowiak JW, Martinez GV, Gillies RJ, (2011) Imaging pH and metastasis. Nmr Biomed 24: 582-591.
-
(2011)
Nmr Biomed
, vol.24
, pp. 582-591
-
-
Hashim, A.I.1
Zhang, X.M.2
Wojtkowiak, J.W.3
Martinez, G.V.4
Gillies, R.J.5
-
42
-
-
0029939371
-
Defective pH regulation of acidic compartments in human breast cancer cells (MCF-7) is normalized in adriamycin-resistant cells (MCF-7adr)
-
Schindler M, Grabski S, Hoff E, Simon SM, (1996) Defective pH regulation of acidic compartments in human breast cancer cells (MCF-7) is normalized in adriamycin-resistant cells (MCF-7adr). Biochemistry 35: 2811-2817.
-
(1996)
Biochemistry
, vol.35
, pp. 2811-2817
-
-
Schindler, M.1
Grabski, S.2
Hoff, E.3
Simon, S.M.4
-
43
-
-
80052868049
-
Imaging the extracellular pH of tumors by MRI after injection of a single cocktail of T1 and T2 contrast agents
-
Martinez GV, Zhang X, García-Martín ML, Morse DL, Woods M, et al. (2011) Imaging the extracellular pH of tumors by MRI after injection of a single cocktail of T1 and T2 contrast agents. NMR Biomed 24: 1380-1391.
-
(2011)
NMR Biomed
, vol.24
, pp. 1380-1391
-
-
Martinez, G.V.1
Zhang, X.2
García-Martín, M.L.3
Morse, D.L.4
Woods, M.5
-
44
-
-
0345687957
-
Lipid-drug association enhanced HIV-1 protease inhibitor indinavir localization in lymphoid tissues and viral load reduction: A proof of concept study in HIV-2(287)-infected macaques
-
Kinman L, Brodie SJ, Tsai CC, Bui T, Larsen K, et al. (2003) Lipid-drug association enhanced HIV-1 protease inhibitor indinavir localization in lymphoid tissues and viral load reduction: A proof of concept study in HIV-2(287)-infected macaques. Jaids-J Acq Imm Def 34: 387-397.
-
(2003)
Jaids-J Acq Imm Def
, vol.34
, pp. 387-397
-
-
Kinman, L.1
Brodie, S.J.2
Tsai, C.C.3
Bui, T.4
Larsen, K.5
-
45
-
-
39749120051
-
pH-dependent interactions of indinavir and lipids in nanoparticlies and their ability to entrap a solute
-
Choi SU, Bui T, Ho RJY, (2008) pH-dependent interactions of indinavir and lipids in nanoparticlies and their ability to entrap a solute. J Pharm Sci 97: 931-943.
-
(2008)
J Pharm Sci
, vol.97
, pp. 931-943
-
-
Choi, S.U.1
Bui, T.2
Ho, R.J.Y.3
-
46
-
-
33745096804
-
Optimization of lipid-indinavir complexes for localization in lymphoid tissues of HIV-infected macaques
-
Kinman L, Bui T, Larsen K, Tsai CC, Anderson D, et al. (2006) Optimization of lipid-indinavir complexes for localization in lymphoid tissues of HIV-infected macaques. Jaids-J Acq Imm Def 42: 155-161.
-
(2006)
Jaids-J Acq Imm Def
, vol.42
, pp. 155-161
-
-
Kinman, L.1
Bui, T.2
Larsen, K.3
Tsai, C.C.4
Anderson, D.5
-
47
-
-
32944460139
-
Regulation of survivin by ErbB2 signaling: Therapeutic implications for ErbB2-overexpressing breast cancers
-
Xia WL, Bisi J, Strum J, Liu LH, Carrick K, et al. (2006) Regulation of survivin by ErbB2 signaling: Therapeutic implications for ErbB2-overexpressing breast cancers. Cancer Res 66: 1640-1647.
-
(2006)
Cancer Res
, vol.66
, pp. 1640-1647
-
-
Xia, W.L.1
Bisi, J.2
Strum, J.3
Liu, L.H.4
Carrick, K.5
-
48
-
-
79959448584
-
Examining the role of cyclin D1 in breast cancer
-
Velasco-Velazquez MA, Li Z, Casimiro M, Loro E, Homsi N, et al. (2011) Examining the role of cyclin D1 in breast cancer. Future Oncol 7: 753-765.
-
(2011)
Future Oncol
, vol.7
, pp. 753-765
-
-
Velasco-Velazquez, M.A.1
Li, Z.2
Casimiro, M.3
Loro, E.4
Homsi, N.5
-
49
-
-
78751607122
-
Characteristics of triple-negative breast cancer
-
de Ruijter TC, Veeck J, de Hoon JPJ, van Engeland M, Tjan-Heijnen VC, (2011) Characteristics of triple-negative breast cancer. J Cancer Res Clin 137: 183-192.
-
(2011)
J Cancer Res Clin
, vol.137
, pp. 183-192
-
-
de Ruijter, T.C.1
Veeck, J.2
de Hoon, J.P.J.3
van Engeland, M.4
Tjan-Heijnen, V.C.5
-
50
-
-
4544353596
-
Lithium bromide, an inexpensive and efficient catalyst for opening of epoxide rings by amines at room temperature under solvent-free condition
-
Chakraborti AK, Rudrawar S, Kondaskar A, (2004) Lithium bromide, an inexpensive and efficient catalyst for opening of epoxide rings by amines at room temperature under solvent-free condition. Eur J Org Chem 17: 3597-3600.
-
(2004)
Eur J Org Chem
, vol.17
, pp. 3597-3600
-
-
Chakraborti, A.K.1
Rudrawar, S.2
Kondaskar, A.3
-
51
-
-
80052233389
-
Endosome maturation
-
Huotari J, Helenius A, (2011) Endosome maturation. Embo J 30: 3481-3500.
-
(2011)
Embo J
, vol.30
, pp. 3481-3500
-
-
Huotari, J.1
Helenius, A.2
-
52
-
-
33947385343
-
Calcium and survivin are involved in the induction of apoptosis by dihydroartemisinin in human lung cancer SPC-A-1 cells
-
Mu D, Chen W, Yu B, Zhang C, Zhang Y, et al. (2007) Calcium and survivin are involved in the induction of apoptosis by dihydroartemisinin in human lung cancer SPC-A-1 cells. Methods Findings Exp Clin 29: 33-38.
-
(2007)
Methods Findings Exp Clin
, vol.29
, pp. 33-38
-
-
Mu, D.1
Chen, W.2
Yu, B.3
Zhang, C.4
Zhang, Y.5
-
53
-
-
34548088377
-
Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive Wnt/beta-catenin pathway
-
Li L-N, Zhang H-D, Yuan S-J, Tian Z-Y, Wang L, et al. (2007) Artesunate attenuates the growth of human colorectal carcinoma and inhibits hyperactive Wnt/beta-catenin pathway. Int J Cancer 121: 1360-1365.
-
(2007)
Int J Cancer
, vol.121
, pp. 1360-1365
-
-
Li, L.-N.1
Zhang, H.-D.2
Yuan, S.-J.3
Tian, Z.-Y.4
Wang, L.5
-
54
-
-
50149115578
-
Cancer cells survive with survivin
-
Yamamoto H, Ngan CY, Monden M, (2008) Cancer cells survive with survivin. Cancer Sci 99: 1709-1714.
-
(2008)
Cancer Sci
, vol.99
, pp. 1709-1714
-
-
Yamamoto, H.1
Ngan, C.Y.2
Monden, M.3
-
55
-
-
34548574823
-
YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts
-
Nakahara T, Takeuchi M, Kinoyama I, Minematsu T, Shirasuna K, et al. (2007) YM155, a novel small-molecule survivin suppressant, induces regression of established human hormone-refractory prostate tumor xenografts. Cancer Res 67: 8014-8021.
-
(2007)
Cancer Res
, vol.67
, pp. 8014-8021
-
-
Nakahara, T.1
Takeuchi, M.2
Kinoyama, I.3
Minematsu, T.4
Shirasuna, K.5
-
56
-
-
55949118445
-
Phase I and Pharmacokinetic Study of YM155, a Small-Molecule Inhibitor of Survivin
-
Tolcher AW, Mita A, Lewis LD, Garrett CR, Till E, et al. (2008) Phase I and Pharmacokinetic Study of YM155, a Small-Molecule Inhibitor of Survivin. J Clin Oncol 26: 5198-5203.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5198-5203
-
-
Tolcher, A.W.1
Mita, A.2
Lewis, L.D.3
Garrett, C.R.4
Till, E.5
-
57
-
-
69249155033
-
Cyclin D1 Degradation Is Sufficient to Induce G(1) Cell Cycle Arrest despite Constitutive Expression of Cyclin E2 in Ovarian Cancer Cells
-
Masamha CP, Benbrook DM, (2009) Cyclin D1 Degradation Is Sufficient to Induce G(1) Cell Cycle Arrest despite Constitutive Expression of Cyclin E2 in Ovarian Cancer Cells. Cancer Res 69: 6565-6572.
-
(2009)
Cancer Res
, vol.69
, pp. 6565-6572
-
-
Masamha, C.P.1
Benbrook, D.M.2
-
58
-
-
70449105984
-
Suppression of Cancer Cell Growth by Promoting Cyclin D1 Degradation
-
Shan J, Zhao W, Gu W, (2009) Suppression of Cancer Cell Growth by Promoting Cyclin D1 Degradation. Mol Cell 36: 469-476.
-
(2009)
Mol Cell
, vol.36
, pp. 469-476
-
-
Shan, J.1
Zhao, W.2
Gu, W.3
-
59
-
-
37049183697
-
Human-Breast Cancer - Correlation of Relapse and Survival With Amplification of the HER-2 Neu Oncogene
-
Slamon DJ, Clark GM, Wong SG, Levin WJ, Ullrich A, et al. (1987) Human-Breast Cancer- Correlation of Relapse and Survival With Amplification of the HER-2 Neu Oncogene. Science 235: 177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
-
60
-
-
79953207364
-
Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase
-
Garrett JT, Olivares MG, Rinehart C, Granja-Ingram ND, Sanchez V, et al. (2011) Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase. P Natl A Sci USA 108: 5021-5026.
-
(2011)
P Natl A Sci USA
, vol.108
, pp. 5021-5026
-
-
Garrett, J.T.1
Olivares, M.G.2
Rinehart, C.3
Granja-Ingram, N.D.4
Sanchez, V.5
-
61
-
-
79957915754
-
ErbB3 Ablation Impairs PI3K/Akt-Dependent Mammary Tumorigenesis
-
Cook RS, Garrett JT, Sanchez V, Stanford JC, Young C, et al. (2011) ErbB3 Ablation Impairs PI3K/Akt-Dependent Mammary Tumorigenesis. Cancer Res 71: 3941-3951.
-
(2011)
Cancer Res
, vol.71
, pp. 3941-3951
-
-
Cook, R.S.1
Garrett, J.T.2
Sanchez, V.3
Stanford, J.C.4
Young, C.5
-
62
-
-
0037118575
-
AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival
-
Bacus SS, Altomare DA, Lyass L, Chin DM, Farrell MP, et al. (2002) AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival. Oncogene 21: 3532-3540.
-
(2002)
Oncogene
, vol.21
, pp. 3532-3540
-
-
Bacus, S.S.1
Altomare, D.A.2
Lyass, L.3
Chin, D.M.4
Farrell, M.P.5
-
63
-
-
0042307325
-
The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
-
Holbro T, Beerli RR, Maurer F, Koziczak M, Barbas CF, et al. (2003) The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. P Natl A Sci USA 100: 8933-8938.
-
(2003)
P Natl A Sci USA
, vol.100
, pp. 8933-8938
-
-
Holbro, T.1
Beerli, R.R.2
Maurer, F.3
Koziczak, M.4
Barbas, C.F.5
-
64
-
-
78449303095
-
The role of HER3, the unpretentious member of the HER family, in cancer biology and cancer therapeutics
-
Amin DN, Campbell MR, Moasser MM, (2010) The role of HER3, the unpretentious member of the HER family, in cancer biology and cancer therapeutics. Semin Cell Dev Biol 21: 944-960.
-
(2010)
Semin Cell Dev Biol
, vol.21
, pp. 944-960
-
-
Amin, D.N.1
Campbell, M.R.2
Moasser, M.M.3
-
65
-
-
79955515280
-
Resistance to HER2-directed antibodies and tyrosine kinase inhibitors
-
Garrett JT, Arteaga CL, (2011) Resistance to HER2-directed antibodies and tyrosine kinase inhibitors. Cancer Biol Ther 11: 793-800.
-
(2011)
Cancer Biol Ther
, vol.11
, pp. 793-800
-
-
Garrett, J.T.1
Arteaga, C.L.2
|