Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

Malaria Journal

Volumn 10, Issue , 2011, Pages

  Morris, Carrie A ^a   Duparc, Stephan ^b   Borghini Fuhrer, Isabelle ^b   Jung, Donald ^c   Shin, Chang Sik ^d   Fleckenstein, Lawrence ^a  

^a UNIVERSITY OF IOWA   (United States)

^b International Center Cointrin   (Switzerland)

^c Pharmaceutical Research Services   (United States)

^d Shin Poong Pharmaceuticals   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE; ARTESUNATE; ATOVAQUONE PLUS PROGUANIL; CHLORPROGUANIL; DAPSONE; DIHYDROARTEMISININ; MEFLOQUINE; PYRIMETHAMINE; PYRONARIDINE; SULFADOXINE; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE;

AREA UNDER THE CURVE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG ELIMINATION; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG PROTEIN BINDING; FOOD DRUG INTERACTION; FOOD INTAKE; HUMAN; LIPID DIET; LIVER BLOOD FLOW; MALARIA; MALARIA FALCIPARUM; MAXIMUM PLASMA CONCENTRATION; MONOTHERAPY; PREGNANCY; REVIEW; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION; ULTRAFILTRATION; BIOAVAILABILITY; HALF LIFE TIME; INTRAMUSCULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; METABOLIC CLEARANCE RATE; ORAL DRUG ADMINISTRATION; RECTAL DRUG ADMINISTRATION; TIME;

ADMINISTRATION, ORAL; ADMINISTRATION, RECTAL; ANTIMALARIALS; ARTEMISININS; BIOLOGICAL AVAILABILITY; HALF-LIFE; HUMANS; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAVENOUS; METABOLIC CLEARANCE RATE; TIME FACTORS;

EID: 80052673399     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-10-263     Document Type: Review

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