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Volumn 8, Issue 3, 2013, Pages

HIV-1 Gp120 Protein Downregulates Nef Induced IL-6 Release in Immature Dentritic Cells through Interplay of DC-SIGN

Author keywords

[No Author keywords available]

Indexed keywords

CD209 ANTIGEN; GLYCOPROTEIN GP 120; INTERLEUKIN 10; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NEF PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR ALPHA;

EID: 84875033768     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059073     Document Type: Article
Times cited : (22)

References (50)
  • 2
  • 3
    • 0035838984 scopus 로고    scopus 로고
    • Dendritic cells: specialized and regulated antigen processing machines
    • Mellman I, Steinman RM, (2001) Dendritic cells: specialized and regulated antigen processing machines. Cell 106: 255-258.
    • (2001) Cell , vol.106 , pp. 255-258
    • Mellman, I.1    Steinman, R.M.2
  • 4
    • 0037039379 scopus 로고    scopus 로고
    • Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance
    • Steinman RM, Nussenzweig MC, (2002) Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance. Proc Natl Acad Sci USA 99: 351-358.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 351-358
    • Steinman, R.M.1    Nussenzweig, M.C.2
  • 5
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau J, Steinman RM, (1998) Dendritic cells and the control of immunity. Nature 392: 245-252.
    • (1998) Nature , vol.392 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 6
    • 0033012398 scopus 로고    scopus 로고
    • Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease
    • Berger EA, Murphy PM, Farber JM, (1999) Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annu Rev Immunol 17: 657-700.
    • (1999) Annu Rev Immunol , vol.17 , pp. 657-700
    • Berger, E.A.1    Murphy, P.M.2    Farber, J.M.3
  • 7
    • 0030777412 scopus 로고    scopus 로고
    • Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways
    • Blauvelt A, Asada H, Saville MW, Klaus-Kovtun V, Altman DJ, et al. (1997) Productive infection of dendritic cells by HIV-1 and their ability to capture virus are mediated through separate pathways. J Clin Invest 100: 2043-2053.
    • (1997) J Clin Invest , vol.100 , pp. 2043-2053
    • Blauvelt, A.1    Asada, H.2    Saville, M.W.3    Klaus-Kovtun, V.4    Altman, D.J.5
  • 8
    • 77949824729 scopus 로고    scopus 로고
    • Preserved MHC class II antigen processing in monocytes from HIV-infected individuals
    • Woc-Colburn L, Smultea L, Ramachandra L, Canaday DH, (2010) Preserved MHC class II antigen processing in monocytes from HIV-infected individuals. PLoS One 5: e9491.
    • (2010) PLoS One , vol.5
    • Woc-Colburn, L.1    Smultea, L.2    Ramachandra, L.3    Canaday, D.H.4
  • 9
    • 0034598905 scopus 로고    scopus 로고
    • DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells
    • Geijtenbeek TB, Kwon DS, Torensma R, van Vliet SJ, van Duijnhoven GC, et al. (2000) DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells. Cell 100: 587-597.
    • (2000) Cell , vol.100 , pp. 587-597
    • Geijtenbeek, T.B.1    Kwon, D.S.2    Torensma, R.3    van Vliet, S.J.4    van Duijnhoven, G.C.5
  • 11
    • 0034843054 scopus 로고    scopus 로고
    • Bitter-sweet symphony: defining the role of dendritic cell gp120 receptors in HIV infection
    • Turville SG, Cameron PU, Arthos J, MacDonald K, Clark G, et al. (2001) Bitter-sweet symphony: defining the role of dendritic cell gp120 receptors in HIV infection. J Clin Virol 22: 229-239.
    • (2001) J Clin Virol , vol.22 , pp. 229-239
    • Turville, S.G.1    Cameron, P.U.2    Arthos, J.3    MacDonald, K.4    Clark, G.5
  • 12
    • 0036172314 scopus 로고    scopus 로고
    • DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection
    • Kwon DS, Gregorio G, Bitton N, Hendrickson WA, Littman DR, (2002) DC-SIGN-mediated internalization of HIV is required for trans-enhancement of T cell infection. Immunity 16: 135-144.
    • (2002) Immunity , vol.16 , pp. 135-144
    • Kwon, D.S.1    Gregorio, G.2    Bitton, N.3    Hendrickson, W.A.4    Littman, D.R.5
  • 13
    • 0038025223 scopus 로고    scopus 로고
    • Recruitment of HIV and its receptors to dendritic cell-T cell junctions
    • McDonald D, Wu L, Bohks SM, KewalRamani VN, Unutmaz D, et al. (2003) Recruitment of HIV and its receptors to dendritic cell-T cell junctions. Science 300: 1295-1297.
    • (2003) Science , vol.300 , pp. 1295-1297
    • McDonald, D.1    Wu, L.2    Bohks, S.M.3    KewalRamani, V.N.4    Unutmaz, D.5
  • 14
    • 0028835788 scopus 로고
    • Brief report: absence of intact Nef sequences in a long-term survivor with nonprogressive HIV-1 infection
    • Kirchhoff F, Greenough TC, Brettler DB, Sullivan JL, Desrosiers RC, (1995) Brief report: absence of intact Nef sequences in a long-term survivor with nonprogressive HIV-1 infection. N Engl J Med 332: 228.
    • (1995) N Engl J Med , vol.332 , pp. 228
    • Kirchhoff, F.1    Greenough, T.C.2    Brettler, D.B.3    Sullivan, J.L.4    Desrosiers, R.C.5
  • 15
    • 0033526798 scopus 로고    scopus 로고
    • Defective Nef alleles in a cohort of hemophiliacs with progressing and nonprogressing HIV-1 infection
    • Brambilla A, Turchetto L, Gatti A, Bovolenta C, Veglia F, et al. (1999) Defective Nef alleles in a cohort of hemophiliacs with progressing and nonprogressing HIV-1 infection. Virology 259: 349.
    • (1999) Virology , vol.259 , pp. 349
    • Brambilla, A.1    Turchetto, L.2    Gatti, A.3    Bovolenta, C.4    Veglia, F.5
  • 16
    • 0025743306 scopus 로고
    • Importance of the Nef gene for maintenance of high virus loads and for development of AIDS
    • Kestler HW, Ringler DJ, Mori K, Panicali DL, Sehgal PK, et al. (1991) Importance of the Nef gene for maintenance of high virus loads and for development of AIDS. Cell 65: 651-662.
    • (1991) Cell , vol.65 , pp. 651-662
    • Kestler, H.W.1    Ringler, D.J.2    Mori, K.3    Panicali, D.L.4    Sehgal, P.K.5
  • 17
    • 0032538278 scopus 로고    scopus 로고
    • Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice
    • Hanna Z, Kay DG, Rebai N, Guimond A, Jothy S, et al. (1998) Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice. Cell 95: 163-175.
    • (1998) Cell , vol.95 , pp. 163-175
    • Hanna, Z.1    Kay, D.G.2    Rebai, N.3    Guimond, A.4    Jothy, S.5
  • 18
    • 0029015330 scopus 로고
    • Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis
    • Aiken C, Trono D, (1995) Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis. J Virol 69: 5048-5056.
    • (1995) J Virol , vol.69 , pp. 5048-5056
    • Aiken, C.1    Trono, D.2
  • 19
    • 0028006247 scopus 로고
    • The human immunodeficiency virus-1 Nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages
    • Miller MD, Warmerdam MT, Gaston I, Greene WC, Feinberg MB, (1994) The human immunodeficiency virus-1 Nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages. J Exp Med 179: 101-113.
    • (1994) J Exp Med , vol.179 , pp. 101-113
    • Miller, M.D.1    Warmerdam, M.T.2    Gaston, I.3    Greene, W.C.4    Feinberg, M.B.5
  • 20
    • 0030576919 scopus 로고    scopus 로고
    • Soluble Nef antigen of HIV-1 is cytotoxic for human CD4+T cells
    • Fujii Y, Otake K, Tashiro M, Adachi A, (1996) Soluble Nef antigen of HIV-1 is cytotoxic for human CD4+T cells. FEBS Lett 393: 93-96.
    • (1996) FEBS Lett , vol.393 , pp. 93-96
    • Fujii, Y.1    Otake, K.2    Tashiro, M.3    Adachi, A.4
  • 21
    • 1542345590 scopus 로고    scopus 로고
    • Chemokine receptor utilization and macrophage signaling by human immunodeficiency virus type 1 gp120: Implications for neuropathogenesis
    • Yi Y, Lee C, Liu QH, Freedman BD, Collman RG, (2004) Chemokine receptor utilization and macrophage signaling by human immunodeficiency virus type 1 gp120: Implications for neuropathogenesis. J Neurovirol 10: 91-96.
    • (2004) J Neurovirol , vol.10 , pp. 91-96
    • Yi, Y.1    Lee, C.2    Liu, Q.H.3    Freedman, B.D.4    Collman, R.G.5
  • 22
    • 0027999216 scopus 로고
    • Cytokine expression of HIV-infected monocytes/macrophages at the single-cell level
    • Glienke W, Esser R, von Briesen H, Schuster K, Müller S, et al. (1994) Cytokine expression of HIV-infected monocytes/macrophages at the single-cell level. Res Virol 145: 193-197.
    • (1994) Res Virol , vol.145 , pp. 193-197
    • Glienke, W.1    Esser, R.2    von Briesen, H.3    Schuster, K.4    Müller, S.5
  • 23
    • 0028244039 scopus 로고
    • HIV-1 induces tumour necrosis factor and IL-1 gene expression in primary human macrophages independent of productive infection
    • Herbein G, Keshav S, Collin M, Montaner LJ, Gordon S, (1994) HIV-1 induces tumour necrosis factor and IL-1 gene expression in primary human macrophages independent of productive infection. Clin Exp Immunol 95: 442-449.
    • (1994) Clin Exp Immunol , vol.95 , pp. 442-449
    • Herbein, G.1    Keshav, S.2    Collin, M.3    Montaner, L.J.4    Gordon, S.5
  • 24
    • 0035340992 scopus 로고    scopus 로고
    • HIV-1 gp120 stimulates the production of beta-chemokines in human peripheral blood monocytes through a CD4- independent mechanism
    • Fantuzzi L, Canini I, Belardelli F, Gessani S, (2001) HIV-1 gp120 stimulates the production of beta-chemokines in human peripheral blood monocytes through a CD4- independent mechanism. J Immunol 166: 5381-5387.
    • (2001) J Immunol , vol.166 , pp. 5381-5387
    • Fantuzzi, L.1    Canini, I.2    Belardelli, F.3    Gessani, S.4
  • 25
    • 16844372394 scopus 로고    scopus 로고
    • HIV-1 Nef mediates post-translational down-regulation and redistribution of the mannose receptor
    • Vigerust DJ, Egan BS, Shepherd VL, (2005) HIV-1 Nef mediates post-translational down-regulation and redistribution of the mannose receptor. J. Leukoc. Biol 77: 522-534.
    • (2005) J. Leukoc. Biol , vol.77 , pp. 522-534
    • Vigerust, D.J.1    Egan, B.S.2    Shepherd, V.L.3
  • 26
    • 33847617830 scopus 로고    scopus 로고
    • HIV-1 gp120 inhibits TLR9-mediated activation and IFN-α secretion in Plasmacytoid dendritic cells
    • Martinelli E, Cicala C, Van Ryk D, Goode DJ, Macleod K, et al. (2007) HIV-1 gp120 inhibits TLR9-mediated activation and IFN-α secretion in Plasmacytoid dendritic cells. Proc Natl Acad Sci USA 104: 3396-3401.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 3396-3401
    • Martinelli, E.1    Cicala, C.2    Van Ryk, D.3    Goode, D.J.4    Macleod, K.5
  • 27
    • 0035892099 scopus 로고    scopus 로고
    • HIV-1 gp120 and chemokine activation of Pyk2 and mitogen- activated protein kinases in primary macrophages mediated by calcium-dependent, pertussis toxin-insensitive chemokine receptor signaling
    • Del Corno M, Liu QH, Schols D, de Clercq E, Gessani S, et al. (2001) HIV-1 gp120 and chemokine activation of Pyk2 and mitogen- activated protein kinases in primary macrophages mediated by calcium-dependent, pertussis toxin-insensitive chemokine receptor signaling. Blood 98: 2909-2916.
    • (2001) Blood , vol.98 , pp. 2909-2916
    • Del Corno, M.1    Liu, Q.H.2    Schols, D.3    de Clercq, E.4    Gessani, S.5
  • 28
    • 0034755687 scopus 로고    scopus 로고
    • Induction of rapid and extensive beta-chemokine synthesis in macrophages by human immunodeficiency virus type 1 and gp120, independently of their coreceptor phenotype
    • Choe W, Volsky DJ, Potash MJ, (2001) Induction of rapid and extensive beta-chemokine synthesis in macrophages by human immunodeficiency virus type 1 and gp120, independently of their coreceptor phenotype. J Virol 75: 10738-10745.
    • (2001) J Virol , vol.75 , pp. 10738-10745
    • Choe, W.1    Volsky, D.J.2    Potash, M.J.3
  • 29
    • 25644440748 scopus 로고    scopus 로고
    • HIV-1 gp120-induced TNF-alpha production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen- activated protein (MAP) kinase pathways
    • Lee C, Tomkowicz B, Freedman BD, Collman RG, (2005) HIV-1 gp120-induced TNF-alpha production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen- activated protein (MAP) kinase pathways. J Leukoc Biol 78: 1016-1023.
    • (2005) J Leukoc Biol , vol.78 , pp. 1016-1023
    • Lee, C.1    Tomkowicz, B.2    Freedman, B.D.3    Collman, R.G.4
  • 30
    • 0025951640 scopus 로고
    • The HIV-1 gp120 envelope protein has the intrinsic capacity to stimulate monokine secretion
    • Clouse KA, Cosentino LM, Weih KA, Pyle SW, Robbins PB, et al. (1991) The HIV-1 gp120 envelope protein has the intrinsic capacity to stimulate monokine secretion. J Immunol 147: 2892-2901.
    • (1991) J Immunol , vol.147 , pp. 2892-2901
    • Clouse, K.A.1    Cosentino, L.M.2    Weih, K.A.3    Pyle, S.W.4    Robbins, P.B.5
  • 31
    • 79959316890 scopus 로고    scopus 로고
    • Effects of HIV-1 Nef on virus co-receptor expression and cytokine release in human bladder, laryngeal, and intestinal epithelial cell lines
    • Quaranta MG, Falzano L, Vincentini O, Fiorentini C, Giordani L, et al. (2011) Effects of HIV-1 Nef on virus co-receptor expression and cytokine release in human bladder, laryngeal, and intestinal epithelial cell lines. Viral Immunol 24: 245-250.
    • (2011) Viral Immunol , vol.24 , pp. 245-250
    • Quaranta, M.G.1    Falzano, L.2    Vincentini, O.3    Fiorentini, C.4    Giordani, L.5
  • 32
    • 84859570010 scopus 로고    scopus 로고
    • Exogenous Nef induces proinflammatory signaling events in murine macrophages
    • Mangino G, Serra V, Borghi P, Percario ZA, Horenkamp FA, et al. (2012) Exogenous Nef induces proinflammatory signaling events in murine macrophages. Viral Immunol 25: 117-130.
    • (2012) Viral Immunol , vol.25 , pp. 117-130
    • Mangino, G.1    Serra, V.2    Borghi, P.3    Percario, Z.A.4    Horenkamp, F.A.5
  • 33
    • 15844389650 scopus 로고    scopus 로고
    • HIV-1 entry into CD4+cells is mediated by the chemokine receptor CC-CKR-5
    • Dragic T, Litwin V, Allaway GP, Martin SR, Huang Y, et al. (1996) HIV-1 entry into CD4+cells is mediated by the chemokine receptor CC-CKR-5. Nature 381: 667-673.
    • (1996) Nature , vol.381 , pp. 667-673
    • Dragic, T.1    Litwin, V.2    Allaway, G.P.3    Martin, S.R.4    Huang, Y.5
  • 34
    • 37349066496 scopus 로고    scopus 로고
    • HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells
    • Shan M, Klasse PJ, Banerjee K, Dey AK, Iyer SP, et al. (2007) HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells. PLoS Pathog 3: e169.
    • (2007) PLoS Pathog , vol.3
    • Shan, M.1    Klasse, P.J.2    Banerjee, K.3    Dey, A.K.4    Iyer, S.P.5
  • 35
    • 70349201241 scopus 로고    scopus 로고
    • Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori
    • Gringhuis SI, den Dunnen J, Litjens M, van der Vlist M, Geijtenbeek TBH, (2009) Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori. Nat Immunol 10: 1081-1088.
    • (2009) Nat Immunol , vol.10 , pp. 1081-1088
    • Gringhuis, S.I.1    den Dunnen, J.2    Litjens, M.3    van der Vlist, M.4    Geijtenbeek, T.B.H.5
  • 36
    • 20444411532 scopus 로고    scopus 로고
    • Second nature: biological functions of the Raf-1 "kinase"
    • Baccarini M, (2005) Second nature: biological functions of the Raf-1 "kinase". FEBS Lett 579: 3271-3277.
    • (2005) FEBS Lett , vol.579 , pp. 3271-3277
    • Baccarini, M.1
  • 37
    • 0034657336 scopus 로고    scopus 로고
    • The role of STATs in transcriptional control and their impact on cellular function
    • Bromberg J, Darnell JE Jr, (2000) The role of STATs in transcriptional control and their impact on cellular function. Oncogene 19: 2468-2473.
    • (2000) Oncogene , vol.19 , pp. 2468-2473
    • Bromberg, J.1    Darnell Jr., J.E.2
  • 38
    • 0032996486 scopus 로고    scopus 로고
    • The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus
    • Heim MH, (1999) The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus. J Recept Signal Transduct Res 19: 75-120.
    • (1999) J Recept Signal Transduct Res , vol.19 , pp. 75-120
    • Heim, M.H.1
  • 39
    • 0032213273 scopus 로고    scopus 로고
    • Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice
    • Takeda K, Kaisho T, Yoshida N, Takeda J, Kishimoto T, et al. (1998) Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice. J Immunol 161: 4652-4660.
    • (1998) J Immunol , vol.161 , pp. 4652-4660
    • Takeda, K.1    Kaisho, T.2    Yoshida, N.3    Takeda, J.4    Kishimoto, T.5
  • 40
    • 52949090018 scopus 로고    scopus 로고
    • SOCS regulation of the JAK/STAT signalling pathway
    • Croker BA, Kiu H, Nicholson SE, (2008) SOCS regulation of the JAK/STAT signalling pathway. Semin Cell Dev Biol 19: 414-422.
    • (2008) Semin Cell Dev Biol , vol.19 , pp. 414-422
    • Croker, B.A.1    Kiu, H.2    Nicholson, S.E.3
  • 42
    • 10744223504 scopus 로고    scopus 로고
    • HIV type 1-infected dendritic cells induce apoptotic death in infected and uninfected primary CD4 T lymphocytes
    • Lichtner M, Marañón C, Vidalain PO, Azocar O, Hanau D, et al. (2004) HIV type 1-infected dendritic cells induce apoptotic death in infected and uninfected primary CD4 T lymphocytes. AIDS Res Hum Retroviruses 20: 175-182.
    • (2004) AIDS Res Hum Retroviruses , vol.20 , pp. 175-182
    • Lichtner, M.1    Marañón, C.2    Vidalain, P.O.3    Azocar, O.4    Hanau, D.5
  • 43
    • 79957880451 scopus 로고    scopus 로고
    • CD4+T cell depletion in human immunodeficiency virus (HIV) infection: role of apoptosis
    • Février M, Dorgham K, Rebollo A, (2011) CD4+T cell depletion in human immunodeficiency virus (HIV) infection: role of apoptosis. Viruses 3: 586-612.
    • (2011) Viruses , vol.3 , pp. 586-612
    • Février, M.1    Dorgham, K.2    Rebollo, A.3
  • 44
    • 0036187980 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Nef binds to tumor suppressor p53 and protects cells against p53-mediated apoptosis
    • Greenway AL, McPhee DA, Allen K, Johnstone R, Holloway G, et al. (2002) Human immunodeficiency virus type 1 Nef binds to tumor suppressor p53 and protects cells against p53-mediated apoptosis. J Virol 76: 2692-2702.
    • (2002) J Virol , vol.76 , pp. 2692-2702
    • Greenway, A.L.1    McPhee, D.A.2    Allen, K.3    Johnstone, R.4    Holloway, G.5
  • 45
    • 0035848864 scopus 로고    scopus 로고
    • HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell
    • Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC, (2001) HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature 410: 834-838.
    • (2001) Nature , vol.410 , pp. 834-838
    • Geleziunas, R.1    Xu, W.2    Takeda, K.3    Ichijo, H.4    Greene, W.C.5
  • 46
    • 0035173735 scopus 로고    scopus 로고
    • HIV-1 Nef associated PAK and PI3- kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals
    • Wolf D, Witte V, Laffert B, Blume K, Stromer E, et al. (2001) HIV-1 Nef associated PAK and PI3- kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals. Nat Med 7: 1217-1224.
    • (2001) Nat Med , vol.7 , pp. 1217-1224
    • Wolf, D.1    Witte, V.2    Laffert, B.3    Blume, K.4    Stromer, E.5
  • 47
    • 0033551829 scopus 로고    scopus 로고
    • Roles of CD4 and Coreceptors in Binding, Endocytosis, and Proteolysis of gp120 Envelope Glycoproteins Derived from Human Immunodeficiency Virus Type 1
    • Kozak SL, Kuhmann SE, Platt EJ, Kabat D, (1999) Roles of CD4 and Coreceptors in Binding, Endocytosis, and Proteolysis of gp120 Envelope Glycoproteins Derived from Human Immunodeficiency Virus Type 1. J Biol Chem 274: 23499-23507.
    • (1999) J Biol Chem , vol.274 , pp. 23499-23507
    • Kozak, S.L.1    Kuhmann, S.E.2    Platt, E.J.3    Kabat, D.4
  • 48
    • 0022495870 scopus 로고
    • Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone
    • Adachi A, Gendelman HE, Koenig S, Folks T, Willey R, et al. (1986) Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone. J Virol 59: 284-291.
    • (1986) J Virol , vol.59 , pp. 284-291
    • Adachi, A.1    Gendelman, H.E.2    Koenig, S.3    Folks, T.4    Willey, R.5
  • 49
    • 0028956139 scopus 로고
    • In vitro human immunodeficiency virus-1infection of purified hematopoietic progenitors in single-cell culture
    • Chelucci C, Hassan HJ, Locardi C, Bulgarini D, Pelosi E, et al. (1995) In vitro human immunodeficiency virus-1infection of purified hematopoietic progenitors in single-cell culture. Blood 85: 1181-1187.
    • (1995) Blood , vol.85 , pp. 1181-1187
    • Chelucci, C.1    Hassan, H.J.2    Locardi, C.3    Bulgarini, D.4    Pelosi, E.5
  • 50
    • 3142688998 scopus 로고    scopus 로고
    • Rap1 signaling is required for suppression of Ras-generated reactive oxygen species and protection against oxidative stress in T lymphocytes
    • Remans PHJ, Gringhuis SI, van Laar JM, Sanders ME, Papendrecht-van der Voort EAMet al. (2004). Rap1 signaling is required for suppression of Ras-generated reactive oxygen species and protection against oxidative stress in T lymphocytes. J. Immunol.173, 920-931.
    • (2004) J. Immunol , vol.173 , pp. 920-931
    • Remans, P.H.J.1    Gringhuis, S.I.2    van Laar, J.M.3    Sanders, M.E.4    Papendrecht-van der Voort, E.A.M.5


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