Beneficial effect of a weight-stable, low-fat/low-saturated fat/low-glycaemic index diet to reduce liver fat in older subjects

British Journal of Nutrition

Volumn 109, Issue 6, 2013, Pages 1096-1104

  Utzschneider, Kristina M ^a,b   Bayer Carter, Jennifer L ^a,c   Arbuckle, Matthew D ^a   Tidwell, Jaime M ^a   Richards, Todd L ^c   Craft, Suzanne ^a,c  

^a VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Dietary fat; Glycaemic index; Non alcoholic fatty liver; Saturated fat

Indexed keywords

CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SATURATED FATTY ACID; TRIACYLGLYCEROL;

AGED; ARTICLE; BODY FAT DISTRIBUTION; BODY MASS; CALORIC INTAKE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; DOUBLE BLIND PROCEDURE; FAT CONTENT; FATTY LIVER; FEMALE; FOOD COMPOSITION; GLUCOSE BLOOD LEVEL; GLYCEMIC INDEX; HOMEOSTASIS; HUMAN; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID DIET; LIPID STORAGE; LOW FAT DIET; MALE; MATSUDA INDEX; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORAL GLUCOSE TOLERANCE TEST; PARALLEL DESIGN; RANDOMIZED CONTROLLED TRIAL; THERAPY EFFECT; TREATMENT DURATION; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT CHANGE;

AGED; BODY FAT DISTRIBUTION; BODY MASS INDEX; BODY WEIGHT; DIET; DIET, FAT-RESTRICTED; DIET, HIGH-FAT; DOUBLE-BLIND METHOD; ENERGY INTAKE; FATTY LIVER; FEMALE; GLYCEMIC INDEX; HUMANS; INSULIN RESISTANCE; LIPIDS; MAGNETIC RESONANCE SPECTROSCOPY; MALE;

EID: 84875020011     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114512002966     Document Type: Article

References (53)

1. Browning JD, Szczepaniak LS, Dobbins R, et al. (2004)Prevalence of hepatic steatosis in an urban population inthe United States: impact of ethnicity. Hepatology 40,1387-1395. (Pubitemid 39657013)
2. Frith J, Day CP, Henderson E, et al. (2009) Non-alcoholicfatty liver disease in older people. Gerontology 55, 607-613.
3. Donnelly KL, Smith CI, Schwarzenberg SJ, et al. (2005)Sources of fatty acids stored in liver and secreted via lipoproteinsin patients with nonalcoholic fatty liver disease. J ClinInvest 115, 1343-1351. (Pubitemid 40629054)
4. Lovejoy JC, Smith SR, Champagne CM, et al. (2002) Effects ofdiets enriched in saturated (palmitic), monounsaturated(oleic), or trans (elaidic) fatty acids on insulin sensitivityand substrate oxidation in healthy adults. Diabetes Care25, 1283-1288. (Pubitemid 41071133)
5. Vessby B, Unsitupa M, Hermansen K, et al. (2001) Substitutingdietary saturated for monounsaturated fat impairs insulinsensitivity in healthy men and women: The KANWU Study.Diabetologia 44, 312-319. (Pubitemid 32234457)
6. Xiao C, Giacca A, Carpentier A, et al. (2006) Differentialeffects of monounsaturated, polyunsaturated and saturatedfat ingestion on glucose-stimulated insulin secretion, sensitivityand clearance in overweight and obese, non-diabetichumans. Diabetologia 49, 1371-1379.
7. Proietto J, Filippis A, Nakhla C, et al. (1999) Nutrient-inducedinsulin resistance. Mol Cell Endocrinol 151, 143-149.
8. Bessesen DH (2001) The role of carbohydrates in insulinresistance. J Nutr 131, 2782S-2786S.
9. McLaughlin T, Yee G, Glassford A, et al. (2011) Use of a twostageinsulin infusion study to assess the relationshipbetween insulin suppression of lipolysis and insulinmediatedglucose uptake in overweight/obese, nondiabeticwomen. Metabolism 60, 1741-1747.
10. Browning JD & Horton JD (2004) Molecular mediators ofhepatic steatosis and liver injury. J Clin Invest 114, 147-152. (Pubitemid 39071617)
11. Wolever TM, Yang M, Zeng XY, et al. (2006) Food glycemicindex, as given in glycemic index tables, is a significantdeterminant of glycemic responses elicited by compositebreakfast meals. Am J Clin Nutr 83, 1306-1312. (Pubitemid 44713060)
12. Fried SK & Rao SP (2003) Sugars, hypertriglyceridemia, andcardiovascular disease. Am J Clin Nutr 78, 873S-880S.
13. Brynes AE, Mark Edwards C, Ghatei MA, et al. (2003) A randomisedfour-intervention crossover study investigating theeffect of carbohydrates on daytime profiles of insulin, glucose,non-esterified fatty acids and triacylglycerols inmiddle-aged men. Br J Nutr 89, 207-218. (Pubitemid 36215859)
14. Tiikkainen M, Bergholm R, Vehkavaara S, et al. (2003) Effectsof identical weight loss on body composition and features ofinsulin resistance in obese women with high and low liverfat content. Diabetes 52, 701-707. (Pubitemid 36323577)
15. Vilar L, Oliveira CP, Faintuch J, et al. (2008) High-fat diet: atrigger of non-alcoholic steatohepatitis? Preliminary findingsin obese subjects. Nutrition 24, 1097-1102.
16. Toshimitsu K, Matsuura B, Ohkubo I, et al. (2007) Dietaryhabits and nutrient intake in non-alcoholic steatohepatitis.Nutrition 23, 46-52. (Pubitemid 44959764)
17. Assy N, Nasser G, Kamayse I, et al. (2008) Soft drink consumptionlinked with fatty liver in the absence of traditionalrisk factors. Can J Gastroenterol 22, 811-816.
18. Valtuena S, Pellegrini N, Ardigo D, et al. (2006) Dietary glycemicindex and liver steatosis. Am J Clin Nutr 84, 136-142,quiz 268-139.
19. Bortolotti M, Kreis R, Debard C, et al. (2009) High proteinintake reduces intrahepatocellular lipid deposition inhumans. Am J Clin Nutr 90, 1002-1010.
20. Sobrecases H, Le KA, Bortolotti M, et al. (2010) Effects ofshort-term overfeeding with fructose, fat and fructose plusfat on plasma and hepatic lipids in healthy men. DiabetesMetab 36, 244-246.
21. Ngo Sock ET, Le KA, Ith M, et al. (2010) Effects of a shorttermoverfeeding with fructose or glucose in healthyyoung males. Br J Nutr 103, 939-943.
22. Zivkovic AM, German JB & Sanyal AJ (2007) Comparativereview of diets for the metabolic syndrome: implicationsfor nonalcoholic fatty liver disease. Am J Clin Nutr 86,285-300. (Pubitemid 47256910)
23. Huang MA, Greenson JK, Chao C, et al. (2005) One-yearintense nutritional counseling results in histologicalimprovement in patients with non-alcoholic steatohepatitis:a pilot study. Am J Gastroenterol 100, 1072-1081. (Pubitemid 40769044)
24. Promrat K, Kleiner DE, Niemeier HM, et al. (2010) Randomizedcontrolled trial testing the effects of weight loss on nonalcoholicsteatohepatitis. Hepatology 51, 121-129.
25. Lazo M, Solga SF, Horska A, et al. (2010) Effect of a 12-monthintensive lifestyle intervention on hepatic steatosis in adultswith type 2 diabetes. Diabetes Care 33, 2156-2163.
26. Shah K, Stufflebam A, Hilton TN, et al. (2009) Diet and exerciseinterventions reduce intrahepatic fat content andimprove insulin sensitivity in obese older adults. Obesity17, 2162-2168.
27. Westerbacka J, Lammi K, Hakkinen AM, et al. (2005) Dietaryfat content modifies liver fat in overweight nondiabetic subjects.J Clin Endocrinol Metab 90, 2804-2809. (Pubitemid 40686327)
28. van Herpen NA, Schrauwen-Hinderling V, Schaart G, et al.(2011) Three weeks on a high-fat diet increases intrahepaticlipid accumulation and decreases metabolic flexibility inhealthy overweight men. J Clin Endocrinol Metab 96,E691-E695.
29. Bayer-Carter JL, Green PS, Montine TJ, et al. (2011) Dietintervention and cerebrospinal fluid biomarkers in amnesticmild cognitive impairment. Arch Neurol 68, 743-752.
30. USDA Standard Reference 18 and Food and Nutrient Databasefor Dietary Studies 1.0 http://www.ars usda.gov/Services/docs.htm?docid1208231
31. http://www.ars.usda.gov/Services/docs.htm?docid1208231. Mifflin MD, Jeor ST, Hill LA, et al. (1990) A new predictiveequation for resting energy expenditure in healthy individuals.Am J Clin Nutr 51, 241-247.
32. Harris JA & Benedict FG (1919) A Biometric Study of BasalMetabolism in Man. Washington, DC: Carnegie Institutionof Washington.
33. Longo R, Ricci C, Masutti F, et al. (1993) Fatty infiltration ofthe liver. Quantification by 1H localized magnetic resonancespectroscopy and comparison with computed tomography.Invest Radiol 28, 297-302. (Pubitemid 24079682)
34. Szczepaniak LS, Nurenberg P, Leonard D, et al. (2005) Magneticresonance spectroscopy to measure hepatic triglyceridecontent: prevalence of hepatic steatosis in the general population.Am J Physiol 288, E462-E468. FSLview http://www.fmrib.ox.ac.uk/fsl/fslview/index.html36 (Pubitemid 40110657)
35. FSLview. http://www.fmrib.ox.ac.uk/fsl/fslview/index.html36. Craft S, Newcomer J, Kanne S, et al. (1996) Memoryimprovement following induced hyperinsulinemia in Alzheimer'sdisease. Neurobiol Aging 17, 123-130. (Pubitemid 26019103)
36. Friedewald WT, Levy RI & Fredrickson DS (1972) Estimationof the concentration of low-density lipoprotein cholesterol inplasma, without use of the preparative ultracentrifuge. ClinChem 18, 499-502.
37. Matthews DR, Hosker JP, Rudenski AS, et al. (1985) Homeostasismodel assessment: insulin resistance and b-cell functionfrom fasting plasma glucose and insulin concentrationsin man. Diabetologia 28, 412-419. (Pubitemid 15018832)
38. Matsuda M & DeFronzo RA (1999) Insulin sensitivity indicesobtained from oral glucose tolerance testing: comparisonwith the euglycemic insulin clamp. Diabetes Care 22,1462-1470. (Pubitemid 29418240)
39. Hudgins LC, Hellerstein M, Seidman C, et al. (1996) Humanfatty acid synthesis is stimulated by a eucaloric low fat, highcarbohydrate diet. J Clin Invest 97, 2081-2091. (Pubitemid 26143963)
40. Hudgins LC, Seidman CE, Diakun J, et al. (1998) Human fattyacid synthesis is reduced after the substitution of dietarystarch for sugar. Am J Clin Nutr 67, 631-639. (Pubitemid 28153165)
41. Browning JD, Baker JA, Rogers T, et al. (2011) Short-termweight loss and hepatic triglyceride reduction: evidence ofa metabolic advantage with dietary carbohydrate restriction.Am J Clin Nutr 93, 1048-1052.
42. Kabir M, Rizkalla SW, Quignard-Boulange A, et al. (1998) Ahigh glycemic index starch diet affects lipid storage-relatedenzymes in normal and to a lesser extent in diabetic rats.J Nutr 128, 1878-1883. (Pubitemid 28509849)
43. Isken F, Klaus S, Petzke KJ, et al. (2009) Impairment of fatoxidation under high vs low glycemic index diet occursprior to the development of an obese phenotype. Am J PhysiolEndocrinol Metab 298, E287-E295.
44. Subramanian S, Goodspeed L, Wang S, et al. (2011) Dietarycholesterol exacerbates hepatic steatosis and inflammation inobese LDL receptor-deficient mice. J Lipid Res 52,1626-1635. USDA What we eat in America http://www.ars.usda. gov/Services/docs.htm?docid14 1834947.
45. USDA, What we eat in America. http://www.ars.usda.gov/Services/docs.htm? docid1834947. Kechagias S, Ernersson A, Dahlqvist O, et al. (2008) Fastfood-based hyper-alimentation can induce rapid and profoundelevation of serum alanine aminotransferase inhealthy subjects. Gut 57, 649-654. (Pubitemid 351579979)
46. Jump DB & Clarke SD (1999) Regulation of gene expressionby dietary fat. Annu Rev Nutr 19, 63-90. (Pubitemid 29380597)
47. Hussein O, Grosovski M, Lasri E, et al. (2007) Monounsaturatedfat decreases hepatic lipid content in non-alcoholicfatty liver disease in rats. World J Gastroenterol 13, 361-368. (Pubitemid 46178969)
48. Retzlaff BM, Walden CE, Dowdy AA, et al. (1995) Changes inplasma triacylglycerol concentrations among free-livinghyperlipidemic men adopting different carbohydrate intakesover 2 y: the Dietary Alternatives Study. Am J Clin Nutr 62,988-995.
49. Gannon MC & Nuttall FQ (2004) Effect of a high-protein,low- carbohydrate diet on blood glucose control in peoplewith type 2 diabetes. Diabetes 53, 2375-2382. (Pubitemid 39145592)
50. Livesey G, Taylor R, Hulshof T, et al. (2008) Glycemicresponse and health-a systematic review and meta-analysis:relations between dietary glycemic properties andhealth outcomes. Am J Clin Nutr 87, 258S-268S.
51. Thomas DE & Elliott EJ (2010) The use of low-glycaemicindex diets in diabetes control. Br J Nutr 104, 797-802.
52. Perez-Jimenez F, Lopez-Miranda J, Pinillos MD, et al. (2001)A Mediterranean and a high-carbohydrate diet improve glucosemetabolism in healthy young persons. Diabetologia 44,2038-2043. (Pubitemid 33124050)
53. Eckel RH, Hernandez TL, Bell ML, et al. (2006) Carbohydratebalance predicts weight and fat gain in adults. Am J Clin Nutr83, 803-808. (Pubitemid 44713143)