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Volumn 178, Issue 1, 2013, Pages 100-106

Dehydroepiandrosterone and dehydroepiandrosterone sulfate: Anabolic, neuroprotective, and neuroexcitatory properties in military men

Author keywords

[No Author keywords available]

Indexed keywords

AMYLASE; HYDROCORTISONE; NERVE GROWTH FACTOR; PRASTERONE; PRASTERONE SULFATE; TESTOSTERONE;

EID: 84875001534     PISSN: 00264075     EISSN: 1930613X     Source Type: Journal    
DOI: 10.7205/MILMED-D-12-00296     Document Type: Article
Times cited : (19)

References (33)
  • 1
    • 0032515989 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids
    • Baulieu EE, Robel P: Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids. Proc Natl Acad Sci 1998; 95: 4089-91.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 4089-4091
    • Baulieu, E.E.1    Robel, P.2
  • 2
    • 0024064517 scopus 로고
    • Molecular biology of steroid hormone synthesis
    • Miller WL: Molecular biology of steroid hormone synthesis. Endocr Rev 1988; 9: 295-318.
    • (1988) Endocr Rev , vol.9 , pp. 295-318
    • Miller, W.L.1
  • 3
    • 10644266103 scopus 로고    scopus 로고
    • Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones
    • Payne AH, Hales DB: Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocr Rev 2004; 25(6): 947-70.
    • (2004) Endocr Rev , vol.25 , Issue.6 , pp. 947-970
    • Payne, A.H.1    Hales, D.B.2
  • 4
    • 0033103126 scopus 로고    scopus 로고
    • Dehydroepiandrosterone antagonizes the neurotoxic effects of corticosterone and translocation of stress-activated protein kinase 3 in hippocampal primary cultures
    • Kimonides VG, Spillantini MG, Sofroniew MV, Fawcett JW, Herbert J: Dehydroepiandrosterone antagonizes the neurotoxic effects of corticosterone and translocation of stress-activated protein kinase 3 in hippocampal primary cultures. Neuroscience 1999; 89: 429-36.
    • (1999) Neuroscience , vol.89 , pp. 429-436
    • Kimonides, V.G.1    Spillantini, M.G.2    Sofroniew, M.V.3    Fawcett, J.W.4    Herbert, J.5
  • 5
    • 84862825158 scopus 로고    scopus 로고
    • Continuous de novo synthesis of neurosteroids is required for normal synaptic transmission and plasticity in the dentate gyrus of the rat hippocampus
    • Tanaka M, Sokabe M: Continuous de novo synthesis of neurosteroids is required for normal synaptic transmission and plasticity in the dentate gyrus of the rat hippocampus. Neuropharmacology 2012; 62: 2373-87.
    • (2012) Neuropharmacology , vol.62 , pp. 2373-2387
    • Tanaka, M.1    Sokabe, M.2
  • 6
    • 79955514139 scopus 로고    scopus 로고
    • Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis
    • Lazaridis I, Charalampopoulos I, Alexaki VI, et al: Neurosteroid dehydroepiandrosterone interacts with nerve growth factor (NGF) receptors, preventing neuronal apoptosis. PLoS Biol 2011; 9(4): e1001051.
    • (2011) PLoS Biol , vol.9 , Issue.4
    • Lazaridis, I.1    Charalampopoulos, I.2    Alexaki, V.I.3
  • 7
    • 84555188263 scopus 로고    scopus 로고
    • Neurosteroid binding sites on the GABA(A) receptor complex as novel targets for therapeutics to reduce alcohol abuse and dependence
    • [published online ahead of print October 31, 2011]. doi: 10.1155/2011/926361
    • HulinMW, Amato RJ, Porter JR, FilipeanuCM, Winsauer PJ:Neurosteroid binding sites on the GABA(A) receptor complex as novel targets for therapeutics to reduce alcohol abuse and dependence [published online ahead of print October 31, 2011]. Adv Pharmacol Sci. doi: 10.1155/2011/926361.
    • Adv Pharmacol Sci.
    • Hulin, M.W.1    Amato, R.J.2    Porter, J.R.3    Filipeanu, C.M.4    Winsauer, P.J.5
  • 8
    • 84055200579 scopus 로고    scopus 로고
    • DHEAS induces short-term potentiation via the activation of metabotropic glutamate receptor in the rat hippocampus
    • Xu Y, Tanaka M, Chen L, Sokabe M: DHEAS induces short-term potentiation via the activation of metabotropic glutamate receptor in the rat hippocampus. Hippocampus 2012; 22: 707-22.
    • (2012) Hippocampus , vol.22 , pp. 707-722
    • Xu, Y.1    Tanaka, M.2    Chen, L.3    Sokabe, M.4
  • 9
    • 0033586349 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage
    • Bastianetto S, Ramassamy C, Poirier J, Quiron R: Dehydroepiandrosterone (DHEA) protects hippocampal cells from oxidative stress-induced damage. Brain Res Mol Brain Res 1999; 66: 35-41.
    • (1999) Brain Res Mol Brain Res , vol.66 , pp. 35-41
    • Bastianetto, S.1    Ramassamy, C.2    Poirier, J.3    Quiron, R.4
  • 10
    • 0032516063 scopus 로고    scopus 로고
    • Dehydroepiandrosterone: A potential signaling molecule for neurocortical organization during development
    • Compagnone NA, Mellon SH: Dehydroepiandrosterone: a potential signaling molecule for neurocortical organization during development. Proc Natl Acad Sci 1998; 95: 4678-83.
    • (1998) Proc Natl Acad Sci , vol.95 , pp. 4678-4683
    • Compagnone, N.A.1    Mellon, S.H.2
  • 11
    • 0036460078 scopus 로고    scopus 로고
    • Dehydroepiandrosterone (DHEA) stimulates neurogenesis in the hippocampus of the rat, promotes survival of newly formed neurons and prevents corticosterone induced suppression
    • Karishma KK, Herbert J: Dehydroepiandrosterone (DHEA) stimulates neurogenesis in the hippocampus of the rat, promotes survival of newly formed neurons and prevents corticosterone induced suppression. Eur J Neurosci 2002; 16: 445-53.
    • (2002) Eur J Neurosci , vol.16 , pp. 445-453
    • Karishma, K.K.1    Herbert, J.2
  • 12
    • 78650079014 scopus 로고    scopus 로고
    • The neurosteroid dehydroepiandrosterone (DHEA) and its metabolites alter 5-HT neuronal activity via modulation of GABAA receptors
    • Gartside SE, Griffith NC, Kaura V, Ingram CD: The neurosteroid dehydroepiandrosterone (DHEA) and its metabolites alter 5-HT neuronal activity via modulation of GABAA receptors. J Psychopharmacol 2010; 24(11): 1717-24.
    • (2010) J Psychopharmacol , vol.24 , Issue.11 , pp. 1717-1724
    • Gartside, S.E.1    Griffith, N.C.2    Kaura, V.3    Ingram, C.D.4
  • 13
    • 79955646384 scopus 로고    scopus 로고
    • Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice
    • Moriguchi 2011
    • Moriguchi 2011 Yamamoto Y, Ikuno T, Fukunaga K: Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice. J Neurochem 2011; 117(5): 879-91.
    • (2011) J Neurochem , vol.117 , Issue.5 , pp. 879-891
    • Yamamoto, Y.1    Ikuno, T.2    Fukunaga, K.3
  • 14
    • 4043096873 scopus 로고    scopus 로고
    • The effects of corticosterone and dehydroepiandrosterone on neurotrophic factor mRNA expression in primary hippocampal and astrocyte cultures
    • Gubba EM Fawcett JW, Herbert J: The effects of corticosterone and dehydroepiandrosterone on neurotrophic factor mRNA expression in primary hippocampal and astrocyte cultures. Brain Res Mol Brain Res 2004; 127(1-2): 48-59.
    • (2004) Brain Res Mol Brain Res , vol.127 , Issue.1-2 , pp. 48-59
    • Gubba, E.M.1    Fawcett, J.W.2    Herbert, J.3
  • 15
    • 77955672345 scopus 로고    scopus 로고
    • Corticosterone and dehydroepiandrosterone have opposing effects on adult neuroplasticity in the avian song control system
    • Newman AE, MacDougall-Shackleton SA, An YS, Kriengwatana B, Soma KK: Corticosterone and dehydroepiandrosterone have opposing effects on adult neuroplasticity in the avian song control system. J Comp Neurol 2010; 518(18): 3662-78.
    • (2010) J Comp Neurol , vol.518 , Issue.18 , pp. 3662-3678
    • Newman, A.E.1    McDougall-Shackleton, S.A.2    An, Y.S.3    Kriengwatana, B.4    Soma, K.K.5
  • 16
    • 34247586012 scopus 로고    scopus 로고
    • Maternal nerve growth factor serum levels in the perinatal period
    • Schulte-Herbrüggen O, Litzke J, Hornych K, et al: Maternal nerve growth factor serum levels in the perinatal period. J Reprod Immunol 2007; 74(1-2): 170-3.
    • (2007) J Reprod Immunol , vol.74 , Issue.1-2 , pp. 170-173
    • Schulte-Herbrüggen, O.1    Litzke, J.2    Hornych, K.3
  • 17
    • 79953878849 scopus 로고    scopus 로고
    • Role of ionotropic glutamate receptors in the regulation of hippocampal norepinephrine output in vivo
    • Dazzi L, Matzeu A, Biggio G: Role of ionotropic glutamate receptors in the regulation of hippocampal norepinephrine output in vivo. Brain Res 2011; 1386: 41-9.
    • (2011) Brain Res , vol.1386 , pp. 41-49
    • Dazzi, L.1    Matzeu, A.2    Biggio, G.3
  • 18
    • 0041324827 scopus 로고    scopus 로고
    • Alprazolam (a benzodiazepine activating GABA receptor) reduces the neuroendocrine responses to insulin-induced hypoglycaemia in humans
    • Giordano R, Grottoli S, Brossa P, et al: Alprazolam (a benzodiazepine activating GABA receptor) reduces the neuroendocrine responses to insulin-induced hypoglycaemia in humans. Clin Endocrinol 2003; 59(3): 314-20.
    • (2003) Clin Endocrinol , vol.59 , Issue.3 , pp. 314-320
    • Giordano, R.1    Grottoli, S.2    Brossa, P.3
  • 19
    • 0032562092 scopus 로고    scopus 로고
    • Modulation of GABA-gated chloride ion influx in the brain by dehydroepiandrosterone and its metabolites
    • Imamura M, Prasad C: Modulation of GABA-gated chloride ion influx in the brain by dehydroepiandrosterone and its metabolites. Biochem Biophys Res Commun 1998; 243(3): 771-5.
    • (1998) Biochem Biophys Res Commun , vol.243 , Issue.3 , pp. 771-775
    • Imamura, M.1    Prasad, C.2
  • 20
    • 0033614716 scopus 로고    scopus 로고
    • Sulfated and unsulfated steroids modulate gamma-aminobutyric acid A receptor function through distinct sites
    • Park-Chung M, Malayev A, Purdy RH, Gibbs TT, Farb DH: Sulfated and unsulfated steroids modulate gamma-aminobutyric acid A receptor function through distinct sites. Brain Res 1999; 830(1): 72-87.
    • (1999) Brain Res , vol.830 , Issue.1 , pp. 72-87
    • Park-Chung, M.1    Malayev, A.2    Purdy, R.H.3    Gibbs, T.T.4    Farb, D.H.5
  • 21
    • 67651014472 scopus 로고    scopus 로고
    • Relationships among plasma dehydroepiandrosterone and dehydroepiandrosterone sulfate, cortisol, symptoms of dissociation, and objective performance in humans exposed to underwater navigation stress
    • Morgan CA III, Rasmusson A, Pietrzak RH, Coric V, Southwick SM: Relationships among plasma dehydroepiandrosterone and dehydroepiandrosterone sulfate, cortisol, symptoms of dissociation, and objective performance in humans exposed to underwater navigation stress. Biol Psychiatry 2009; 66: 334-40.
    • (2009) Biol Psychiatry , vol.66 , pp. 334-340
    • Morgan III, C.A.1    Rasmusson, A.2    Pietrzak, R.H.3    Coric, V.4    Southwick, S.M.5
  • 22
    • 83455219366 scopus 로고    scopus 로고
    • Effects of dehydroepiandrosterone supplementation during stressful military training: A randomized, controlled, double-blind field study
    • Taylor MK, Padilla GA, Stanfill KE, et al: Effects of dehydroepiandrosterone supplementation during stressful military training: a randomized, controlled, double-blind field study. Stress 2012; 15(1): 85-96.
    • (2012) Stress , vol.15 , Issue.1 , pp. 85-96
    • Taylor, M.K.1    Padilla, G.A.2    Stanfill, K.E.3
  • 23
    • 0141678094 scopus 로고    scopus 로고
    • The delayed administration of dehydroepiandrosterone sulfate improves recovery of function after traumatic brain injury in rats
    • Hoffman SW, Virmani S, Simkins RM, Stein DG: The delayed administration of dehydroepiandrosterone sulfate improves recovery of function after traumatic brain injury in rats. J Neurotrauma 2003; 20(9): 859-70.
    • (2003) J Neurotrauma , vol.20 , Issue.9 , pp. 859-870
    • Hoffman, S.W.1    Virmani, S.2    Simkins, R.M.3    Stein, D.G.4
  • 24
    • 0037850007 scopus 로고    scopus 로고
    • A novel dehydroepiandrosterone analog improves functional recovery in a rat traumatic brain injury model
    • Malik AS, Narayan RK, Wendling WW, et al: A novel dehydroepiandrosterone analog improves functional recovery in a rat traumatic brain injury model. J Neurotrauma 2003; 20(5): 463-76.
    • (2003) J Neurotrauma , vol.20 , Issue.5 , pp. 463-476
    • Malik, A.S.1    Narayan, R.K.2    Wendling, W.W.3
  • 25
    • 35549004888 scopus 로고    scopus 로고
    • Integration of salivary biomarkers into developmental and behaviorally-oriented research: Problems and solutions for collecting specimens
    • Granger DA, Kivlighan KT, Fortunato C, et al: Integration of salivary biomarkers into developmental and behaviorally-oriented research: problems and solutions for collecting specimens. Physiol Behav 2007; 92(4): 583-90.
    • (2007) Physiol Behav , vol.92 , Issue.4 , pp. 583-590
    • Granger, D.A.1    Kivlighan, K.T.2    Fortunato, C.3
  • 27
    • 27944490440 scopus 로고    scopus 로고
    • Stress-induced changes in human salivary alpha-amylase activity-associations with adrenergic activity
    • Nater UM, La Marca R, Florin L, et al: Stress-induced changes in human salivary alpha-amylase activity-associations with adrenergic activity. Psychoneuroendocrinology 2006; 31(1): 49-58.
    • (2006) Psychoneuroendocrinology , vol.31 , Issue.1 , pp. 49-58
    • Nater, U.M.1    la Marca, R.2    Florin, L.3
  • 28
    • 27944456500 scopus 로고    scopus 로고
    • Salivary alpha amylase as marker for adrenergic activity during stress: Effect of betablockade
    • Van Stegeren A, Rohleder N, Everaerd W, Wolf OT: Salivary alpha amylase as marker for adrenergic activity during stress: effect of betablockade. Psychoneuroendocrinology 2006; 31(1): 137-41.
    • (2006) Psychoneuroendocrinology , vol.31 , Issue.1 , pp. 137-141
    • van Stegeren, A.1    Rohleder, N.2    Everaerd, W.3    Wolf, O.T.4
  • 30
    • 77956791074 scopus 로고    scopus 로고
    • The importance of covariate selection in controlling for selection bias in observational studies
    • Steiner PM, Cook TD, Shadish WR, Clark MH: The importance of covariate selection in controlling for selection bias in observational studies. Psychol Methods 2010; 15(3): 250-67.
    • (2010) Psychol Methods , vol.15 , Issue.3 , pp. 250-267
    • Steiner, P.M.1    Cook, T.D.2    Shadish, W.R.3    Clark, M.H.4
  • 31
    • 80054114987 scopus 로고    scopus 로고
    • Anxiety and depression: Mouse genetics and pharmacological approaches to the role of GABAA receptor subtypes
    • Smith KS, Rudolph U: Anxiety and depression: mouse genetics and pharmacological approaches to the role of GABAA receptor subtypes. Neuropharmacology 2012; 62(1): 54-62.
    • (2012) Neuropharmacology , vol.62 , Issue.1 , pp. 54-62
    • Smith, K.S.1    Rudolph, U.2
  • 32
    • 1642487147 scopus 로고    scopus 로고
    • Psychobiological mechanisms of resilience and vulnerability: Implications for successful adaptation to extreme stress
    • Charney DS: Psychobiological mechanisms of resilience and vulnerability: implications for successful adaptation to extreme stress. Am J Psychiatry 2004; 161(2): 195-216.
    • (2004) Am J Psychiatry , vol.161 , Issue.2 , pp. 195-216
    • Charney, D.S.1
  • 33
    • 0033980873 scopus 로고    scopus 로고
    • Anti-stress effects of dehydroepiandrosterone: Protection of rats against repeated immobilization stress-induced weight loss, glucocorticoid receptor production, and lipid peroxidation
    • Hu Y, Cardounel A, Gursoy E, Anderson P, Kalimi M: Anti-stress effects of dehydroepiandrosterone: protection of rats against repeated immobilization stress-induced weight loss, glucocorticoid receptor production, and lipid peroxidation. Biochem Pharmacol 2000; 59(7): 753-62.
    • (2000) Biochem Pharmacol , vol.59 , Issue.7 , pp. 753-762
    • Hu, Y.1    Cardounel, A.2    Gursoy, E.3    Anderson, P.4    Kalimi, M.5


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