Supplementation of carnitine leads to an activation of the IGF-1/PI3K/Akt signalling pathway and down regulates the E3 ligase MuRF1 in skeletal muscle of rats

Nutrition and Metabolism

Volumn 10, Issue 1, 2013, Pages

  Keller, Janine ^a   Couturier, Aline ^a   Haferkamp, Melanie ^a   Most, Erika ^a   Eder, Klaus ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Carnitine; IGF 1 PI3K Akt signalling pathway; Muscle; Rat; Ubiquitin proteasome system

Indexed keywords

ATROGIN 1; CARNITINE; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; MUSCLE PROTEIN; MUSCLE RING FINGER 1 PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEASOME; PROTEIN KINASE B; SOMATOMEDIN C; TRANSCRIPTION FACTOR FKHR; TRIPARTITE MOTIF PROTEIN 63; UBIQUITIN; UBIQUITINATED PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOWN REGULATION; DRUG BLOOD LEVEL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; RAT; SIGNAL TRANSDUCTION; SKELETAL MUSCLE;

RATTUS; SUIDAE;

EID: 84874941537     PISSN: None     EISSN: 17437075     Source Type: Journal    
DOI: 10.1186/1743-7075-10-28     Document Type: Article

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