-
1
-
-
0030694189
-
Excess mortality of schizophrenia. A meta-analysis
-
Brown S. Excess mortality of schizophrenia. A meta-analysis. Br J Psychiatry. 1997;171:502-508. (Pubitemid 27527317)
-
(1997)
British Journal of Psychiatry
, vol.171
, Issue.DEC.
, pp. 502-508
-
-
Brown, S.1
-
2
-
-
77950321358
-
Cardiovascular disease mortality in patients with chronic schizophrenia treated with clozapine: A retrospective cohort study
-
Kelly DL, McMahon RP, Liu F, et al. Cardiovascular disease mortality in patients with chronic schizophrenia treated with clozapine: a retrospective cohort study. J Clin Psychiatry. 2010;3:304-311.
-
(2010)
J Clin Psychiatry
, vol.3
, pp. 304-311
-
-
Kelly, D.L.1
McMahon, R.P.2
Liu, F.3
-
3
-
-
54549127387
-
Relative risk of diabetes dyslipidaemia hypertension and the metabolic syndrome in people with severe mental illnesses: Systematic review and metaanalysis
-
September Available at Accessed February 20 2012
-
Osborn DP, Wright CA, Levy G, et al. Relative risk of diabetes, dyslipidaemia, hypertension and the metabolic syndrome in people with severe mental illnesses: systematic review and metaanalysis. BMC Psychiatry [serial online]. September 2008;84:1-14. Available at: http://www.biomedcentral.com/ 1471-244X/8/84. Accessed February 20, 2012.
-
(2008)
BMC Psychiatry [Serial Online]
, vol.84
, pp. 1-14
-
-
Osborn, D.P.1
Wright, C.A.2
Levy, G.3
-
4
-
-
79952395209
-
Physical illness in patients with severe mental disorders I. Prevalence, impact of medications and disparities in health care
-
De Hert M, Correll CU, Bobes J, et al. Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care. World Psychiatry. 2011;1:52-77.
-
(2011)
World Psychiatry.
, vol.1
, pp. 52-77
-
-
De Hert, M.1
Correll, C.U.2
Bobes, J.3
-
5
-
-
79955571576
-
Monitoring and prevalence rates of metabolic syndrome in military veterans with serious mental illness
-
[serial online] May Available at Accessed February 20 2012
-
Khatana SA, Kane J, Taveira TH, et al. Monitoring and prevalence rates of metabolic syndrome in military veterans with serious mental illness. PLoS One [serial online]. May 2011;4:e19298. Available at: http://www.plosone.org/ article/info%3Adoi%2F10.1371%2Fjournal.pone.0019298. Accessed February 20, 2012.
-
(2011)
PLoS One
, vol.4
-
-
Khatana, S.A.1
Kane, J.2
Taveira, T.H.3
-
6
-
-
84864249142
-
Prevalence of metabolic syndrome and metabolic abnormalities in schizophrenia and related disordersVa systematic review and meta-analysis
-
Epub ahead of print
-
Mitchell AJ, Vancampfort D, Sweers K, et al. Prevalence of metabolic syndrome and metabolic abnormalities in schizophrenia and related disordersVa systematic review and meta-analysis. Schizophr Bull. 2011. [Epub ahead of print].
-
(2011)
Schizophr Bull
-
-
Mitchell, A.J.1
Vancampfort, D.2
Sweers, K.3
-
7
-
-
84856466929
-
Metabolic and cardiovascular adverse effects associated with antipsychotic drugs
-
De Hert M, Detraux J, van Winkel R, et al. Metabolic and cardiovascular adverse effects associated with antipsychotic drugs. Nat Rev Endocrinol. 2012;2:114-126.
-
(2012)
Nat Rev Endocrinol
, vol.2
, pp. 114-126
-
-
De Hert, M.1
Detraux, J.2
Van Winkel, R.3
-
8
-
-
70350738289
-
Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents
-
Correll CU, Manu P, Olshanskiy V, et al. Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents. JAMA. 2009;16:1765-1773.
-
(2009)
JAMA
, vol.16
, pp. 1765-1773
-
-
Correll, C.U.1
Manu, P.2
Olshanskiy, V.3
-
9
-
-
77954762965
-
Antipsychotics associated with the development of type 2 diabetes in antipsychotic-naive schizophrenia patients
-
Nielsen J, Skadhede S, Correll CU. Antipsychotics associated with the development of type 2 diabetes in antipsychotic-naive schizophrenia patients. Neuropsychopharmacology. 2010;9:1997-2004.
-
(2010)
Neuropsychopharmacology
, vol.9
, pp. 1997-2004
-
-
Nielsen, J.1
Skadhede, S.2
Correll, C.U.3
-
10
-
-
76649090935
-
Weight gain in antipsychotic-naive patients: A review and meta-analysis
-
Tarricone I, Ferrari Gozzi B, Serretti A, et al. Weight gain in antipsychotic-naive patients: a review and meta-analysis. Psychol Med. 2010;2:187-200.
-
(2010)
Psychol Med
, vol.2
, pp. 187-200
-
-
Tarricone, I.1
Ferrari Gozzi, B.2
Serretti, A.3
-
11
-
-
79953295120
-
Metabolic and endocrine adverse effects of second-generation antipsychotics in children and adolescents: A systematic review of randomized, placebo controlled trials and guidelines for clinical practice
-
De Hert M, Dobbelaere M, Sheridan EM, et al. Metabolic and endocrine adverse effects of second-generation antipsychotics in children and adolescents: a systematic review of randomized, placebo controlled trials and guidelines for clinical practice. Eur Psychiatry. 2011;3:144-158.
-
(2011)
Eur Psychiatry
, vol.3
, pp. 144-158
-
-
De Hert, M.1
Dobbelaere, M.2
Sheridan, E.M.3
-
12
-
-
77957923642
-
Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: A systematic review and meta-analysis
-
Rummel-Kluge C, Komossa K, Schwarz S, et al. Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis. Schizophr Res. 2010;2-3:225-233.
-
(2010)
Schizophr Res
, vol.2-3
, pp. 225-233
-
-
Rummel-Kluge, C.1
Komossa, K.2
Schwarz, S.3
-
13
-
-
43049144928
-
Typical and atypical antipsychotics differentially affect long-term incidence rates of the metabolic syndrome in first-episode patients with schizophrenia: A retrospective chart review
-
De Hert M, Schreurs V, Sweers K, et al. Typical and atypical antipsychotics differentially affect long-term incidence rates of the metabolic syndrome in first-episode patients with schizophrenia: a retrospective chart review. Schizophr Res. 2008;1-3:295-303.
-
(2008)
Schizophr Res
, vol.1-3
, pp. 295-303
-
-
De Hert, M.1
Schreurs, V.2
Sweers, K.3
-
14
-
-
70349194825
-
Obesity, serious mental illness and antipsychotic drugs
-
Holt RI, Peveler RC. Obesity, serious mental illness and antipsychotic drugs. Diabetes Obes Metab. 2009;7:665-679.
-
(2009)
Diabetes Obes Metab
, vol.7
, pp. 665-679
-
-
Holt, R.I.1
Peveler, R.C.2
-
15
-
-
33748786233
-
Food intake and reward mechanisms in patients with schizophrenia: Implications for metabolic disturbances and treatment with second-generation antipsychotic agents
-
DOI 10.1038/sj.npp.1301051, PII 1301051
-
Elman I, Borsook D, Lukas SE. Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents. Neuropsychopharmacology. 2006;10:2091-2120. (Pubitemid 44413188)
-
(2006)
Neuropsychopharmacology
, vol.31
, Issue.10
, pp. 2091-2120
-
-
Elman, I.1
Borsook, D.2
Lukas, S.E.3
-
16
-
-
72149090641
-
Metabolic side effects of antipsychotic drug treatmentVpharmacological mechanisms
-
Reynolds GP, Kirk SL. Metabolic side effects of antipsychotic drug treatmentVpharmacological mechanisms. Pharmacol Ther. 2009;1:169-179.
-
(2009)
Pharmacol Ther
, vol.1
, pp. 169-179
-
-
Reynolds, G.P.1
Kirk, S.L.2
-
18
-
-
77954218128
-
Potential mechanisms of atypical antipsychotic-induced metabolic derangement: Clues for understanding obesity and novel drug design
-
Coccurello R, Moles A. Potential mechanisms of atypical antipsychotic-induced metabolic derangement: clues for understanding obesity and novel drug design. Pharmacol Ther. 2010;3:210-251.
-
(2010)
Pharmacol Ther
, vol.3
, pp. 210-251
-
-
Coccurello, R.1
Moles, A.2
-
19
-
-
79959374794
-
Mechanisms and genetics of antipsychotic-associated weight gain
-
Balt SL, Galloway GP, Baggott MJ, et al. Mechanisms and genetics of antipsychotic-associated weight gain. Clin Pharmacol Ther. 2011; 90:179-183.
-
(2011)
Clin Pharmacol Ther
, vol.90
, pp. 179-183
-
-
Balt, S.L.1
Galloway, G.P.2
Baggott, M.J.3
-
20
-
-
84857356940
-
Pharmacogenetics of antipsychotic-induced weight gain: Review and clinical implications
-
Lett TA, Wallace TJ, Chowdhury NI, et al. Pharmacogenetics of antipsychotic-induced weight gain: review and clinical implications. Mol Psychiatry. 2012;3:242-266.
-
(2012)
Mol Psychiatry
, vol.3
, pp. 242-266
-
-
Lett, T.A.1
Wallace, T.J.2
Chowdhury, N.I.3
-
21
-
-
77953937453
-
Genetic association between TNF-alpha-308 G9A polymorphism and longitudinal weight change during clozapine treatment
-
Wang YC, Bai YM, Chen JY, et al. Genetic association between TNF-alpha-308 G9A polymorphism and longitudinal weight change during clozapine treatment. Hum Psychopharmacol. 2010;4:303-309.
-
(2010)
Hum Psychopharmacol
, vol.4
, pp. 303-309
-
-
Wang, Y.C.1
Bai, Y.M.2
Chen, J.Y.3
-
22
-
-
52649105994
-
Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: A cohort study
-
Ujike H, Nomura A, Morita Y, et al. Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: a cohort study. J Clin Psychiatry. 2008;9:1416-1422.
-
(2008)
J Clin Psychiatry
, vol.9
, pp. 1416-1422
-
-
Ujike, H.1
Nomura, A.2
Morita, Y.3
-
23
-
-
78951469329
-
Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia
-
Jassim G, Ferno J, Theisen FM, et al. Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. Pharmacopsychiatry. 2011;1:15-20.
-
(2011)
Pharmacopsychiatry
, vol.1
, pp. 15-20
-
-
Jassim, G.1
Ferno, J.2
Theisen, F.M.3
-
24
-
-
62649090828
-
HTR2C gene polymorphisms and the metabolic syndrome in patients with schizophrenia: A replication study
-
Mulder H, Cohen D, Scheffer H, et al. HTR2C gene polymorphisms and the metabolic syndrome in patients with schizophrenia: a replication study. J Clin Psychopharmacol. 2009;1:16-20.
-
(2009)
J Clin Psychopharmacol
, vol.1
, pp. 16-20
-
-
Mulder, H.1
Cohen, D.2
Scheffer, H.3
-
25
-
-
0037097014
-
Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism
-
DOI 10.1016/S0140-6736(02)08913-4
-
Reynolds GP, Zhang ZJ, Zhang XB. Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism. Lancet. 2002;9323:2086-2087. (Pubitemid 34680975)
-
(2002)
Lancet
, vol.359
, Issue.9323
, pp. 2086-2087
-
-
Reynolds, G.P.1
Zhang, Z.-J.2
Zhang, X.-B.3
-
26
-
-
79959944606
-
Association of genetic variants of the histamine H1 and muscarinic M3 receptors with BMI and HbA1c values in patients on antipsychotic medication
-
Vehof J, Risselada AJ, Al Hadithy AF, et al. Association of genetic variants of the histamine H1 and muscarinic M3 receptors with BMI and HbA1c values in patients on antipsychotic medication. Psychopharmacology (Berl). 2011;2:257-265.
-
(2011)
Psychopharmacology (Berl)
, vol.2
, pp. 257-265
-
-
Vehof, J.1
Risselada, A.J.2
Al Hadithy, A.F.3
-
27
-
-
78649392014
-
Association between the 1291-C/G polymorphism in the adrenergic alpha-2a receptor and the metabolic syndrome
-
Risselada AJ, Vehof J, Bruggeman R, et al. Association between the 1291-C/G polymorphism in the adrenergic alpha-2a receptor and the metabolic syndrome. J Clin Psychopharmacol. 2010;6:667-671.
-
(2010)
J Clin Psychopharmacol
, vol.6
, pp. 667-671
-
-
Risselada, A.J.1
Vehof, J.2
Bruggeman, R.3
-
28
-
-
79954998186
-
Lipogenic effects of psychotropic drugs: Focus on the SREBP system
-
Ferno J, Skrede S, Vik-Mo AO, et al. Lipogenic effects of psychotropic drugs: focus on the SREBP system. Front Biosci. 2011;16:49-60.
-
(2011)
Front Biosci
, vol.16
, pp. 49-60
-
-
Ferno, J.1
Skrede, S.2
Vik-Mo, A.O.3
-
29
-
-
77957124138
-
Antipsychotic drugs up-regulate lipogenic gene expression by disrupting intracellular trafficking of lipoprotein-derived cholesterol
-
Kristiana I, Sharpe LJ, Catts VS, et al. Antipsychotic drugs up-regulate lipogenic gene expression by disrupting intracellular trafficking of lipoprotein-derived cholesterol. Pharmacogenomics J. 2009;5:396-407.
-
(2009)
Pharmacogenomics J
, vol.5
, pp. 396-407
-
-
Kristiana, I.1
Sharpe, L.J.2
Catts, V.S.3
-
30
-
-
56449085151
-
Association of antipsychotic induced weight gain and body mass index with GNB3 gene: A meta-analysis
-
Souza RP, De Luca V, Muscettola G, et al. Association of antipsychotic induced weight gain and body mass index with GNB3 gene: a meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry. 2008;8:1848-1853.
-
(2008)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.8
, pp. 1848-1853
-
-
Souza, R.P.1
De Luca, V.2
Muscettola, G.3
-
31
-
-
78649362142
-
Effect of FTO, SH2B1, LEP, and LEPR polymorphisms on weight gain associated with antipsychotic treatment
-
Perez-Iglesias R, Mata I, Amado JA, et al. Effect of FTO, SH2B1, LEP, and LEPR polymorphisms on weight gain associated with antipsychotic treatment. J Clin Psychopharmacol. 2010;6:661-666.
-
(2010)
J Clin Psychopharmacol
, vol.6
, pp. 661-666
-
-
Perez-Iglesias, R.1
Mata, I.2
Amado, J.A.3
-
32
-
-
77955055009
-
MTHFR and risk of metabolic syndrome in patients with schizophrenia
-
Van Winkel R, Rutten BP, Peerbooms O, et al. MTHFR and risk of metabolic syndrome in patients with schizophrenia. Schizophr Res. 2010;1-3:193-198.
-
(2010)
Schizophr Res
, vol.1-3
, pp. 193-198
-
-
Van Winkel, R.1
Rutten, B.P.2
Peerbooms, O.3
-
33
-
-
78951488004
-
Clock genes and body composition in patients with schizophrenia under treatment with antipsychotic drugs
-
Moons T, Claes S, Martens GJ, et al. Clock genes and body composition in patients with schizophrenia under treatment with antipsychotic drugs. Schizophr Res. 2011;2-3:187-193.
-
(2011)
Schizophr Res
, vol.2-3
, pp. 187-193
-
-
Moons, T.1
Claes, S.2
Martens, G.J.3
-
34
-
-
73349131110
-
The implication of CNR1 gene's polymorphisms in the modulation of endocannabinoid system effects
-
Dinu IR, Popa S, Bicu M, et al. The implication of CNR1 gene's polymorphisms in the modulation of endocannabinoid system effects. Rom J Intern Med. 2009;1:9-18.
-
(2009)
Rom J Intern Med
, vol.1
, pp. 9-18
-
-
Dinu, I.R.1
Popa, S.2
Bicu, M.3
-
35
-
-
0035985477
-
CNR1, central cannabinoid receptor gene, associated with susceptibility to hebephrenic schizophrenia
-
DOI 10.1038/sj.mp.4001029
-
Ujike H, Takaki M, Nakata K, et al. CNR1, central cannabinoid receptor gene, associated with susceptibility to hebephrenic schizophrenia. Mol Psychiatry. 2002;5:515-518. (Pubitemid 34712904)
-
(2002)
Molecular Psychiatry
, vol.7
, Issue.5
, pp. 515-518
-
-
Ujike, H.1
Takaki, M.2
Nakata, K.3
Tanaka, Y.4
Takeda, T.5
Kodama, M.6
Fujiwara, Y.7
Sakai, A.8
Kuroda, S.9
-
36
-
-
42149110869
-
Cannabinoid receptor 1 gene (CNR1) and susceptibility to a quantitative phenotype for hebephrenic schizophrenia
-
DOI 10.1002/ajmg.b.30592
-
Chavarria-Siles I, Contreras-Rojas J, Hare E, et al. Cannabinoid receptor 1 gene (CNR1) and susceptibility to a quantitative phenotype for hebephrenic schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2008;3:279-284. (Pubitemid 351536789)
-
(2008)
American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics
, vol.147
, Issue.3
, pp. 279-284
-
-
Chavarria-Siles, I.1
Contreras-Rojas, J.2
Hare, E.3
Walss-Bass, C.4
Quezada, P.5
Dassori, A.6
Contreras, S.7
Medina, R.8
Ramirez, M.9
Salazar, R.10
Raventos, H.11
Escamilla, M.A.12
-
37
-
-
45749158085
-
Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations
-
DOI 10.1093/hmg/ddn089
-
Benzinou M, Chevre JC, Ward KJ, et al. Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations. Hum Mol Genet. 2008;13:1916-1921. (Pubitemid 351865840)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.13
, pp. 1916-1921
-
-
Benzinou, M.1
Chevre, J.-C.2
Ward, K.J.3
Lecoeur, C.4
Dina, C.5
Lobbens, S.6
Durand, E.7
Delplanque, J.8
Horber, F.F.9
Heude, B.10
Balkau, B.11
Borch-johnsen, K.12
Jorgensen, T.13
Hansen, T.14
Pedersen, O.15
Meyre, D.16
Froguel, P.17
-
38
-
-
79251486673
-
A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain
-
[serial online]. January Available at Accessed February 20 2012
-
Feng Q, Jiang L, Berg RL, et al. A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain. PLoS One [serial online]. January 2011;12:e15779. Available at: http://www.plosone.org/article/info:doi%2F10.1371%2Fjournal.pone.0015779. Accessed February 20, 2012.
-
(2011)
PLoS One
, vol.12
-
-
Feng, Q.1
Jiang, L.2
Berg, R.L.3
-
39
-
-
50249131267
-
Cannabinoid type-1 receptor gene polymorphisms are associated with central obesity in a Southern Brazilian population
-
Jaeger JP, Mattevi VS, Callegari-Jacques SM, et al. Cannabinoid type-1 receptor gene polymorphisms are associated with central obesity in a Southern Brazilian population. Dis Markers. 2008;1:67-74.
-
(2008)
Dis Markers
, vol.1
, pp. 67-74
-
-
Jaeger, J.P.1
Mattevi, V.S.2
Callegari-Jacques, S.M.3
-
42
-
-
33845656373
-
The endocannabinoid system as a target for the treatment of visceral obesity and metabolic syndrome
-
DOI 10.1196/annals.1367.024, Stress, Obesity, and Metabolic Syndrome
-
Kyrou I, Valsamakis G, Tsigos C. The endocannabinoid system as a target for the treatment of visceral obesity and metabolic syndrome. Ann N Y Acad Sci. 2006;1083:270-305. (Pubitemid 44955478)
-
(2006)
Annals of the New York Academy of Sciences
, vol.1083
, pp. 270-305
-
-
Kyrou, I.1
Valsamakis, G.2
Tsigos, C.3
-
43
-
-
34548538764
-
1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids
-
DOI 10.1038/sj.npp.1301375, PII 1301375
-
Carriba P, Ortiz O, Patkar K, et al. Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids. Neuropsychopharmacology. 2007;11:2249-2259. (Pubitemid 47587686)
-
(2007)
Neuropsychopharmacology
, vol.32
, Issue.11
, pp. 2249-2259
-
-
Carriba, P.1
Ortiz, O.2
Patkar, K.3
Justinova, Z.4
Stroik, J.5
Themann, A.6
Muller, C.7
Woods, A.S.8
Hope, B.T.9
Ciruela, F.10
Casado, V.11
Canela, E.I.12
Lluis, C.13
Goldberg, S.R.14
Moratalla, R.15
Franco, R.16
Ferre, S.17
-
44
-
-
77954954279
-
Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C]OMAR
-
Wong DF, Kuwabara H, Horti AG, et al. Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C]OMAR. Neuroimage. 2010;4:1505-1513.
-
(2010)
Neuroimage
, vol.4
, pp. 1505-1513
-
-
Wong, D.F.1
Kuwabara, H.2
Horti, A.G.3
-
45
-
-
33847359549
-
Rimonabant: A novel selective cannabinoid-1 receptor antagonist for of treatment obesity
-
DOI 10.2146/060258
-
Patel PN, Pathak R. Rimonabant: a novel selective cannabinoid-1 receptor antagonist for treatment of obesity. Am J Health Syst Pharm. 2007;5:481-489. (Pubitemid 46339261)
-
(2007)
American Journal of Health-System Pharmacy
, vol.64
, Issue.5
, pp. 481-489
-
-
Patel, P.N.1
Pathak, R.2
-
46
-
-
80053276336
-
The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant's antiobesity effects in mice
-
Pang Z, Wu NN, Zhao W, et al. The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant's antiobesity effects in mice. Obesity (Silver Spring). 2011;10:1923-1934.
-
(2011)
Obesity (Silver Spring)
, vol.10
, pp. 1923-1934
-
-
Pang, Z.1
Wu, N.N.2
Zhao, W.3
-
47
-
-
53749103705
-
Genetic variation may influence obesity only under conditions of diet: Analysis of three candidate genes
-
Aberle J, Flitsch J, Beck NA, et al. Genetic variation may influence obesity only under conditions of diet: analysis of three candidate genes. Mol Genet Metab. 2008;3:188-191.
-
(2008)
Mol Genet Metab
, vol.3
, pp. 188-191
-
-
Aberle, J.1
Flitsch, J.2
Beck, N.A.3
-
48
-
-
61549101858
-
Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass index
-
Baye TM, Zhang Y, Smith E, et al. Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass index. Pharmacogenomics. 2008;11:1647-1656.
-
(2008)
Pharmacogenomics
, vol.11
, pp. 1647-1656
-
-
Baye, T.M.1
Zhang, Y.2
Smith, E.3
-
49
-
-
34347273447
-
Genetic variations at the endocannabinoid type 1 receptor gene (CNR1) are associated with obesity phenotypes in men
-
DOI 10.1210/jc.2006-2523
-
Russo P, Strazzullo P, Cappuccio FP, et al. Genetic variations at the endocannabinoid type 1 receptor gene (CNR1) are associated with obesity phenotypes in men. J Clin Endocrinol Metab. 2007;6:2382-2386. (Pubitemid 46997151)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.6
, pp. 2382-2386
-
-
Russo, P.1
Strazzullo, P.2
Cappuccio, F.P.3
Tregouet, D.A.4
Lauria, F.5
Loguercio, M.6
Barba, G.7
Versiero, M.8
Siani, A.9
-
50
-
-
78751645595
-
Influence of G1359A polymorphism of the cannabinoid receptor gene on anthropometric parameters and insulin resistance in women with obesity
-
de Luis DA, Gonzalez Sagrado M, Aller R, et al. Influence of G1359A polymorphism of the cannabinoid receptor gene on anthropometric parameters and insulin resistance in women with obesity. Metabolism. 2011;2:272-276.
-
(2011)
Metabolism
, vol.2
, pp. 272-276
-
-
De Luis, D.A.1
Gonzalez Sagrado, M.2
Aller, R.3
-
51
-
-
79960187115
-
Relation of G1359A polymorphism of the cannabinoid receptor (CB1) gene with metabolic syndrome by ATP III classification
-
de Luis DA, Gonzalez Sagrado M, Aller R, et al. Relation of G1359A polymorphism of the cannabinoid receptor (CB1) gene with metabolic syndrome by ATP III classification. Diabetes Metab Res Rev. 2011;5:506-511.
-
(2011)
Diabetes Metab Res Rev
, vol.5
, pp. 506-511
-
-
De Luis, D.A.1
Gonzalez Sagrado, M.2
Aller, R.3
-
52
-
-
78049415493
-
A large-scale candidate gene association study of age at menarche and age at natural menopause
-
He C, Kraft P, Chasman DI, et al. A large-scale candidate gene association study of age at menarche and age at natural menopause. Hum Genet. 2010;5:515-527.
-
(2010)
Hum Genet
, vol.5
, pp. 515-527
-
-
He, C.1
Kraft, P.2
Chasman, D.I.3
-
53
-
-
33947586983
-
No evidence for an involvement of variants in the cannabinoid receptor gene (CNR1) in obesity in German children and adolescents
-
DOI 10.1016/j.ymgme.2007.01.002, PII S1096719207000261
-
Muller TD, Reichwald K, Wermter AK, et al. No evidence for an involvement of variants in the cannabinoid receptor gene (CNR1) in obesity in German children and adolescents. Mol Genet Metab. 2007;4:429-434. (Pubitemid 46484433)
-
(2007)
Molecular Genetics and Metabolism
, vol.90
, Issue.4
, pp. 429-434
-
-
Muller, T.D.1
Reichwald, K.2
Wermter, A.-K.3
Bronner, G.4
Nguyen, T.T.5
Friedel, S.6
Koberwitz, K.7
Engeli, S.8
Lichtner, P.9
Meitinger, T.10
Schafer, H.11
Hebebrand, J.12
Hinney, A.13
-
54
-
-
77951098236
-
A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia
-
Tiwari AK, Zai CC, Likhodi O, et al. A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia. Neuropsychopharmacology. 2010;6:1315-1324.
-
(2010)
Neuropsychopharmacology
, vol.6
, pp. 1315-1324
-
-
Tiwari, A.K.1
Zai, C.C.2
Likhodi, O.3
-
55
-
-
77955129795
-
Endocannabinoid Pro129Thr FAAH functional polymorphism but not 1359G/A CNR1 polymorphism is associated with antipsychotic-induced weight gain
-
Monteleone P, Milano W, Petrella C, et al. Endocannabinoid Pro129Thr FAAH functional polymorphism but not 1359G/A CNR1 polymorphism is associated with antipsychotic-induced weight gain. J Clin Psychopharmacol. 2010;4:441-445.
-
(2010)
J Clin Psychopharmacol
, vol.4
, pp. 441-445
-
-
Monteleone, P.1
Milano, W.2
Petrella, C.3
-
56
-
-
79960835205
-
Cannabinoid type 1 receptor gene polymorphisms are not associated with olanzapine-induced weight gain
-
Park YM, Choi JE, Kang SG, et al. Cannabinoid type 1 receptor gene polymorphisms are not associated with olanzapine-induced weight gain. Hum Psychopharmacol. 2011;4-5:332-337.
-
(2011)
Hum Psychopharmacol
, vol.4-5
, pp. 332-337
-
-
Park, Y.M.1
Choi, J.E.2
Kang, S.G.3
-
58
-
-
33645409466
-
Prevalence of the metabolic syndrome in patients with schizophrenia treated with antipsychotic medication
-
De Hert MA, van Winkel R, Van Eyck D, et al. Prevalence of the metabolic syndrome in patients with schizophrenia treated with antipsychotic medication. Schizophr Res. 2006;1:87-93.
-
(2006)
Schizophr Res
, vol.1
, pp. 87-93
-
-
De Hert, M.A.1
Van Winkel, R.2
Van Eyck, D.3
-
59
-
-
49649112948
-
Psychiatric diagnosis as an independent risk factor for metabolic disturbances: Results from a comprehensive, naturalistic screening program
-
van Winkel R, van Os J, Celic I, et al. Psychiatric diagnosis as an independent risk factor for metabolic disturbances: results from a comprehensive, naturalistic screening program. J Clin Psychiatry. 2008;8:1319-1327.
-
(2008)
J Clin Psychiatry
, vol.8
, pp. 1319-1327
-
-
Van Winkel, R.1
Van Os, J.2
Celic, I.3
-
60
-
-
79952006351
-
Effects of cannabis use on age at onset in schizophrenia and bipolar disorder
-
De Hert M, Wampers M, Jendricko T, et al. Effects of cannabis use on age at onset in schizophrenia and bipolar disorder. Schizophr Res. 2011;1-3:270-276.
-
(2011)
Schizophr Res
, vol.1-3
, pp. 270-276
-
-
De Hert, M.1
Wampers, M.2
Jendricko, T.3
-
61
-
-
27444443876
-
Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute scientific statement
-
DOI 10.1161/CIRCULATIONAHA.105.169404
-
Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation. 2005;17:2735-2752. (Pubitemid 41532612)
-
(2005)
Circulation
, vol.112
, Issue.17
, pp. 2735-2752
-
-
Grundy, S.M.1
Cleeman, J.I.2
Daniels, S.R.3
Donato, K.A.4
Eckel, R.H.5
Franklin, B.A.6
Gordon, D.J.7
Krauss, R.M.8
Savage, P.J.9
Smith Jr., S.C.10
Spertus, J.A.11
Costa, F.12
-
62
-
-
40349084011
-
Diagnosis and classification of diabetes mellitus
-
American Diabetes Association
-
American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2008;31:S55YS60.
-
(2008)
Diabetes Care
, vol.31
-
-
-
63
-
-
79951472497
-
Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: Sibling analysis and proband follow-up
-
van Winkel R. Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up. Arch Gen Psychiatry. 2011;68:148-157.
-
(2011)
Arch Gen Psychiatry
, vol.68
, pp. 148-157
-
-
Van Winkel, R.1
-
64
-
-
70450235344
-
Recovering unused information in genome-wide association studies: The benefit of analyzing SNPs out of Hardy-Weinberg equilibrium
-
Fardo DW, Becker KD, Bertram L, et al. Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy-Weinberg equilibrium. Eur J Hum Genet. 2009;12:1676-1682.
-
(2009)
Eur J Hum Genet
, vol.12
, pp. 1676-1682
-
-
Fardo, D.W.1
Becker, K.D.2
Bertram, L.3
-
65
-
-
0008651450
-
Hardy-Weinberg equilibrium tests and allele frequency estimation
-
Cleves MA. Hardy-Weinberg equilibrium tests and allele frequency estimation. STATA Technical Bulletin. 1999;8:34-37.
-
(1999)
STATA Technical Bulletin
, vol.8
, pp. 34-37
-
-
Cleves, M.A.1
-
66
-
-
79952579297
-
Age at onset of psychotic disorder: Cannabis, BDNF Val66Met, and sex-specific models of gene-environment interaction
-
Decoster J, van Os J, Kenis G, et al. Age at onset of psychotic disorder: cannabis, BDNF Val66Met, and sex-specific models of gene-environment interaction. Am J Med Genet B Neuropsychiatr Genet. 2011;3:363-369.
-
(2011)
Am J Med Genet B Neuropsychiatr Genet
, vol.3
, pp. 363-369
-
-
Decoster, J.1
Van Os, J.2
Kenis, G.3
-
67
-
-
25144501575
-
Genetic association studies
-
DOI 10.1016/S0140-6736(05)67424-7, PII S0140673605674247
-
Cordell HJ, Clayton DG. Genetic association studies. Lancet. 2005;9491:1121-1131. (Pubitemid 41338767)
-
(2005)
Lancet
, vol.366
, Issue.9491
, pp. 1121-1131
-
-
Cordell, H.J.1
Clayton, D.G.2
-
68
-
-
77956270559
-
Polymorphisms in the endocannabinoid receptor 1 in relation to fat mass distribution
-
Frost M, Nielsen TL, Wraae K, et al. Polymorphisms in the endocannabinoid receptor 1 in relation to fat mass distribution. Eur J Endocrinol. 2010;3:407-412.
-
(2010)
Eur J Endocrinol
, vol.3
, pp. 407-412
-
-
Frost, M.1
Nielsen, T.L.2
Wraae, K.3
-
69
-
-
80955158245
-
Endocannabinoid type 1 receptor gene (CNR1) polymorphisms (rs806381, rs10485170, rs6454674, rs2023239) and cardiovascular risk factors in postmenopausal women
-
Laczmanski L, Milewicz A, Dunajska K, et al. Endocannabinoid type 1 receptor gene (CNR1) polymorphisms (rs806381, rs10485170, rs6454674, rs2023239) and cardiovascular risk factors in postmenopausal women. Gynecol Endocrinol. 2011;12:1023-1027.
-
(2011)
Gynecol Endocrinol
, vol.12
, pp. 1023-1027
-
-
Laczmanski, L.1
Milewicz, A.2
Dunajska, K.3
-
70
-
-
79952698829
-
Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women
-
Milewicz A, Tworowska-Bardzinska U, Jedrzejuk D, et al. Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women Int J Obes (Lond). 2011;3:373-377.
-
(2011)
Int J Obes (Lond)
, vol.3
, pp. 373-377
-
-
Milewicz, A.1
Tworowska-Bardzinska, U.2
Jedrzejuk, D.3
-
71
-
-
77956800047
-
G1359A polymorphism in the cannabinoid receptor-1 gene is associated with metabolic syndrome in the Chinese Han population
-
Hu WC, Feng P. G1359A polymorphism in the cannabinoid receptor-1 gene is associated with metabolic syndrome in the Chinese Han population. Arch Med Res. 2010;5:378-382.
-
(2010)
Arch Med Res
, vol.5
, pp. 378-382
-
-
Hu, W.C.1
Feng, P.2
-
72
-
-
84856481281
-
The role of the endocannabinoid system in the neuroendocrine regulation of energy balance
-
Bermudez-Silva FJ, Cardinal P, Cota D. The role of the endocannabinoid system in the neuroendocrine regulation of energy balance. J Psychopharmacol. 2012;26:1-11.
-
(2012)
J Psychopharmacol
, vol.26
, pp. 1-11
-
-
Bermudez-Silva, F.J.1
Cardinal, P.2
Cota, D.3
-
73
-
-
79955632246
-
Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
-
Di Marzo V, Piscitelli F, Mechoulam R. Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes. Handb Exp Pharmacol. 2011;203:75-104.
-
(2011)
Handb Exp Pharmacol
, vol.203
, pp. 75-104
-
-
Di Marzo, V.1
Piscitelli, F.2
Mechoulam, R.3
-
74
-
-
51349153318
-
Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice
-
Osei-Hyiaman D, Liu J, Zhou L, et al. Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice. J Clin Invest. 2008;9:3160-3169.
-
(2008)
J Clin Invest
, vol.9
, pp. 3160-3169
-
-
Osei-Hyiaman, D.1
Liu, J.2
Zhou, L.3
-
75
-
-
84856414714
-
Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice
-
Bell-Anderson KS, Aouad L, Williams H, et al. Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice. Int J Obes (Lond). 2011;12:1539-1548.
-
(2011)
Int J Obes (Lond)
, vol.12
, pp. 1539-1548
-
-
Bell-Anderson, K.S.1
Aouad, L.2
Williams, H.3
-
76
-
-
48149101434
-
The endocannabinoid system in obesity and type 2 diabetes
-
Di Marzo V. The endocannabinoid system in obesity and type 2 diabetes. Diabetologia. 2008;8:1356-1367.
-
(2008)
Diabetologia
, vol.8
, pp. 1356-1367
-
-
Di Marzo, V.1
-
77
-
-
59649102201
-
Altered pattern of cannabinoid type 1 receptor expression in adipose tissue of dysmetabolic and overweight patients
-
Sarzani R, Bordicchia M, Marcucci P, et al. Altered pattern of cannabinoid type 1 receptor expression in adipose tissue of dysmetabolic and overweight patients. Metabolism. 2009;3:361-367.
-
(2009)
Metabolism
, vol.3
, pp. 361-367
-
-
Sarzani, R.1
Bordicchia, M.2
Marcucci, P.3
-
78
-
-
20944436157
-
1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity
-
DOI 10.1172/JCI200523057
-
Osei-Hyiaman D, DePetrillo M, Pacher P, et al. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. J Clin Invest. 2005;5:1298-1305. (Pubitemid 40629049)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.5
, pp. 1298-1305
-
-
Osei-Hyiaman, D.1
DePetrillo, M.2
Pacher, P.3
Liu, J.4
Radaeva, S.5
Batkai, S.6
Harvey-White, J.7
Mackie, K.8
Offertaler, L.9
Wang, L.10
Kunos, G.11
-
79
-
-
85047690626
-
The endogenous cennabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
-
DOI 10.1172/JCI200317725
-
Cota D, Marsicano G, Tschop M, et al. The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest. 2003;3:423-431. (Pubitemid 38063771)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.3
, pp. 423-431
-
-
Cota, D.1
Marsicano, G.2
Tschop, M.3
Grubler, Y.4
Flachskamm, C.5
Schubert, M.6
Auer, D.7
Yassouridis, A.8
Thone-Reineke, C.9
Ortmann, S.10
Tomassoni, F.11
Cervino, C.12
Nisoli, E.13
Linthorst, A.C.E.14
Pasquali, R.15
Lutz, B.16
Stalla, G.K.17
Pagotto, U.18
-
80
-
-
77954371737
-
Expression of cannabinoid CB1 receptors by vagal afferent neurons: Kinetics and role in influencing neurochemical phenotype
-
Burdyga G, Varro A, Dimaline R, et al. Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype. Am J PhysiolGastrointest Liver Physiol. 2010;1:63-69.
-
(2010)
Am J PhysiolGastrointest Liver Physiol
, vol.1
, pp. 63-69
-
-
Burdyga, G.1
Varro, A.2
Dimaline, R.3
-
81
-
-
33947357077
-
Requirement of cannabinoid receptor type 1 for the basal modulation of hypothalamic-pituitary-adrenal axis function
-
DOI 10.1210/en.2005-1649
-
Cota D, Steiner MA, Marsicano G, et al. Requirement of cannabinoid receptor type 1 for the basal modulation of hypothalamic-pituitary-adrenal axis function. Endocrinology. 2007;4:1574-1581. (Pubitemid 46457104)
-
(2007)
Endocrinology
, vol.148
, Issue.4
, pp. 1574-1581
-
-
Cota, D.1
Steiner, M.-A.2
Marsicano, G.3
Cervino, C.4
Herman, J.P.5
Grubler, Y.6
Stalla, J.7
Pasquali, R.8
Lutz, B.9
Stalla, G.K.10
Pagotto, U.11
-
82
-
-
33646856625
-
Ghrelin receptors in rat and human nodose ganglia: Putative role in regulating CB-1 and MCH receptor abundance
-
Burdyga G, Varro A, Dimaline R, et al. Ghrelin receptors in rat and human nodose ganglia: putative role in regulating CB-1 and MCH receptor abundance. Am J Physiol Gastrointest Liver Physiol. 2006;6:1289-1297.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.6
, pp. 1289-1297
-
-
Burdyga, G.1
Varro, A.2
Dimaline, R.3
|