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Volumn 33, Issue 2, 2013, Pages 186-192

CNR1 gene and risk of the metabolic syndrome in patients with schizophrenia

Author keywords

endocannabinoid receptor type 1 gene; metabolic syndrome; schizophrenia

Indexed keywords

CLOZAPINE; ENDOCANNABINOID; ENDOCANNABINOID RECEPTOR 1; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; OLANZAPINE; UNCLASSIFIED DRUG;

EID: 84874939539     PISSN: 02710749     EISSN: 1533712X     Source Type: Journal    
DOI: 10.1097/JCP.0b013e318283925e     Document Type: Article
Times cited : (26)

References (82)
  • 1
    • 0030694189 scopus 로고    scopus 로고
    • Excess mortality of schizophrenia. A meta-analysis
    • Brown S. Excess mortality of schizophrenia. A meta-analysis. Br J Psychiatry. 1997;171:502-508. (Pubitemid 27527317)
    • (1997) British Journal of Psychiatry , vol.171 , Issue.DEC. , pp. 502-508
    • Brown, S.1
  • 2
    • 77950321358 scopus 로고    scopus 로고
    • Cardiovascular disease mortality in patients with chronic schizophrenia treated with clozapine: A retrospective cohort study
    • Kelly DL, McMahon RP, Liu F, et al. Cardiovascular disease mortality in patients with chronic schizophrenia treated with clozapine: a retrospective cohort study. J Clin Psychiatry. 2010;3:304-311.
    • (2010) J Clin Psychiatry , vol.3 , pp. 304-311
    • Kelly, D.L.1    McMahon, R.P.2    Liu, F.3
  • 3
    • 54549127387 scopus 로고    scopus 로고
    • Relative risk of diabetes dyslipidaemia hypertension and the metabolic syndrome in people with severe mental illnesses: Systematic review and metaanalysis
    • September Available at Accessed February 20 2012
    • Osborn DP, Wright CA, Levy G, et al. Relative risk of diabetes, dyslipidaemia, hypertension and the metabolic syndrome in people with severe mental illnesses: systematic review and metaanalysis. BMC Psychiatry [serial online]. September 2008;84:1-14. Available at: http://www.biomedcentral.com/ 1471-244X/8/84. Accessed February 20, 2012.
    • (2008) BMC Psychiatry [Serial Online] , vol.84 , pp. 1-14
    • Osborn, D.P.1    Wright, C.A.2    Levy, G.3
  • 4
    • 79952395209 scopus 로고    scopus 로고
    • Physical illness in patients with severe mental disorders I. Prevalence, impact of medications and disparities in health care
    • De Hert M, Correll CU, Bobes J, et al. Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care. World Psychiatry. 2011;1:52-77.
    • (2011) World Psychiatry. , vol.1 , pp. 52-77
    • De Hert, M.1    Correll, C.U.2    Bobes, J.3
  • 5
    • 79955571576 scopus 로고    scopus 로고
    • Monitoring and prevalence rates of metabolic syndrome in military veterans with serious mental illness
    • [serial online] May Available at Accessed February 20 2012
    • Khatana SA, Kane J, Taveira TH, et al. Monitoring and prevalence rates of metabolic syndrome in military veterans with serious mental illness. PLoS One [serial online]. May 2011;4:e19298. Available at: http://www.plosone.org/ article/info%3Adoi%2F10.1371%2Fjournal.pone.0019298. Accessed February 20, 2012.
    • (2011) PLoS One , vol.4
    • Khatana, S.A.1    Kane, J.2    Taveira, T.H.3
  • 6
    • 84864249142 scopus 로고    scopus 로고
    • Prevalence of metabolic syndrome and metabolic abnormalities in schizophrenia and related disordersVa systematic review and meta-analysis
    • Epub ahead of print
    • Mitchell AJ, Vancampfort D, Sweers K, et al. Prevalence of metabolic syndrome and metabolic abnormalities in schizophrenia and related disordersVa systematic review and meta-analysis. Schizophr Bull. 2011. [Epub ahead of print].
    • (2011) Schizophr Bull
    • Mitchell, A.J.1    Vancampfort, D.2    Sweers, K.3
  • 7
    • 84856466929 scopus 로고    scopus 로고
    • Metabolic and cardiovascular adverse effects associated with antipsychotic drugs
    • De Hert M, Detraux J, van Winkel R, et al. Metabolic and cardiovascular adverse effects associated with antipsychotic drugs. Nat Rev Endocrinol. 2012;2:114-126.
    • (2012) Nat Rev Endocrinol , vol.2 , pp. 114-126
    • De Hert, M.1    Detraux, J.2    Van Winkel, R.3
  • 8
    • 70350738289 scopus 로고    scopus 로고
    • Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents
    • Correll CU, Manu P, Olshanskiy V, et al. Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents. JAMA. 2009;16:1765-1773.
    • (2009) JAMA , vol.16 , pp. 1765-1773
    • Correll, C.U.1    Manu, P.2    Olshanskiy, V.3
  • 9
    • 77954762965 scopus 로고    scopus 로고
    • Antipsychotics associated with the development of type 2 diabetes in antipsychotic-naive schizophrenia patients
    • Nielsen J, Skadhede S, Correll CU. Antipsychotics associated with the development of type 2 diabetes in antipsychotic-naive schizophrenia patients. Neuropsychopharmacology. 2010;9:1997-2004.
    • (2010) Neuropsychopharmacology , vol.9 , pp. 1997-2004
    • Nielsen, J.1    Skadhede, S.2    Correll, C.U.3
  • 10
    • 76649090935 scopus 로고    scopus 로고
    • Weight gain in antipsychotic-naive patients: A review and meta-analysis
    • Tarricone I, Ferrari Gozzi B, Serretti A, et al. Weight gain in antipsychotic-naive patients: a review and meta-analysis. Psychol Med. 2010;2:187-200.
    • (2010) Psychol Med , vol.2 , pp. 187-200
    • Tarricone, I.1    Ferrari Gozzi, B.2    Serretti, A.3
  • 11
    • 79953295120 scopus 로고    scopus 로고
    • Metabolic and endocrine adverse effects of second-generation antipsychotics in children and adolescents: A systematic review of randomized, placebo controlled trials and guidelines for clinical practice
    • De Hert M, Dobbelaere M, Sheridan EM, et al. Metabolic and endocrine adverse effects of second-generation antipsychotics in children and adolescents: a systematic review of randomized, placebo controlled trials and guidelines for clinical practice. Eur Psychiatry. 2011;3:144-158.
    • (2011) Eur Psychiatry , vol.3 , pp. 144-158
    • De Hert, M.1    Dobbelaere, M.2    Sheridan, E.M.3
  • 12
    • 77957923642 scopus 로고    scopus 로고
    • Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: A systematic review and meta-analysis
    • Rummel-Kluge C, Komossa K, Schwarz S, et al. Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: a systematic review and meta-analysis. Schizophr Res. 2010;2-3:225-233.
    • (2010) Schizophr Res , vol.2-3 , pp. 225-233
    • Rummel-Kluge, C.1    Komossa, K.2    Schwarz, S.3
  • 13
    • 43049144928 scopus 로고    scopus 로고
    • Typical and atypical antipsychotics differentially affect long-term incidence rates of the metabolic syndrome in first-episode patients with schizophrenia: A retrospective chart review
    • De Hert M, Schreurs V, Sweers K, et al. Typical and atypical antipsychotics differentially affect long-term incidence rates of the metabolic syndrome in first-episode patients with schizophrenia: a retrospective chart review. Schizophr Res. 2008;1-3:295-303.
    • (2008) Schizophr Res , vol.1-3 , pp. 295-303
    • De Hert, M.1    Schreurs, V.2    Sweers, K.3
  • 14
    • 70349194825 scopus 로고    scopus 로고
    • Obesity, serious mental illness and antipsychotic drugs
    • Holt RI, Peveler RC. Obesity, serious mental illness and antipsychotic drugs. Diabetes Obes Metab. 2009;7:665-679.
    • (2009) Diabetes Obes Metab , vol.7 , pp. 665-679
    • Holt, R.I.1    Peveler, R.C.2
  • 15
    • 33748786233 scopus 로고    scopus 로고
    • Food intake and reward mechanisms in patients with schizophrenia: Implications for metabolic disturbances and treatment with second-generation antipsychotic agents
    • DOI 10.1038/sj.npp.1301051, PII 1301051
    • Elman I, Borsook D, Lukas SE. Food intake and reward mechanisms in patients with schizophrenia: implications for metabolic disturbances and treatment with second-generation antipsychotic agents. Neuropsychopharmacology. 2006;10:2091-2120. (Pubitemid 44413188)
    • (2006) Neuropsychopharmacology , vol.31 , Issue.10 , pp. 2091-2120
    • Elman, I.1    Borsook, D.2    Lukas, S.E.3
  • 16
    • 72149090641 scopus 로고    scopus 로고
    • Metabolic side effects of antipsychotic drug treatmentVpharmacological mechanisms
    • Reynolds GP, Kirk SL. Metabolic side effects of antipsychotic drug treatmentVpharmacological mechanisms. Pharmacol Ther. 2009;1:169-179.
    • (2009) Pharmacol Ther , vol.1 , pp. 169-179
    • Reynolds, G.P.1    Kirk, S.L.2
  • 18
    • 77954218128 scopus 로고    scopus 로고
    • Potential mechanisms of atypical antipsychotic-induced metabolic derangement: Clues for understanding obesity and novel drug design
    • Coccurello R, Moles A. Potential mechanisms of atypical antipsychotic-induced metabolic derangement: clues for understanding obesity and novel drug design. Pharmacol Ther. 2010;3:210-251.
    • (2010) Pharmacol Ther , vol.3 , pp. 210-251
    • Coccurello, R.1    Moles, A.2
  • 19
    • 79959374794 scopus 로고    scopus 로고
    • Mechanisms and genetics of antipsychotic-associated weight gain
    • Balt SL, Galloway GP, Baggott MJ, et al. Mechanisms and genetics of antipsychotic-associated weight gain. Clin Pharmacol Ther. 2011; 90:179-183.
    • (2011) Clin Pharmacol Ther , vol.90 , pp. 179-183
    • Balt, S.L.1    Galloway, G.P.2    Baggott, M.J.3
  • 20
    • 84857356940 scopus 로고    scopus 로고
    • Pharmacogenetics of antipsychotic-induced weight gain: Review and clinical implications
    • Lett TA, Wallace TJ, Chowdhury NI, et al. Pharmacogenetics of antipsychotic-induced weight gain: review and clinical implications. Mol Psychiatry. 2012;3:242-266.
    • (2012) Mol Psychiatry , vol.3 , pp. 242-266
    • Lett, T.A.1    Wallace, T.J.2    Chowdhury, N.I.3
  • 21
    • 77953937453 scopus 로고    scopus 로고
    • Genetic association between TNF-alpha-308 G9A polymorphism and longitudinal weight change during clozapine treatment
    • Wang YC, Bai YM, Chen JY, et al. Genetic association between TNF-alpha-308 G9A polymorphism and longitudinal weight change during clozapine treatment. Hum Psychopharmacol. 2010;4:303-309.
    • (2010) Hum Psychopharmacol , vol.4 , pp. 303-309
    • Wang, Y.C.1    Bai, Y.M.2    Chen, J.Y.3
  • 22
    • 52649105994 scopus 로고    scopus 로고
    • Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: A cohort study
    • Ujike H, Nomura A, Morita Y, et al. Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: a cohort study. J Clin Psychiatry. 2008;9:1416-1422.
    • (2008) J Clin Psychiatry , vol.9 , pp. 1416-1422
    • Ujike, H.1    Nomura, A.2    Morita, Y.3
  • 23
    • 78951469329 scopus 로고    scopus 로고
    • Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia
    • Jassim G, Ferno J, Theisen FM, et al. Association study of energy homeostasis genes and antipsychotic-induced weight gain in patients with schizophrenia. Pharmacopsychiatry. 2011;1:15-20.
    • (2011) Pharmacopsychiatry , vol.1 , pp. 15-20
    • Jassim, G.1    Ferno, J.2    Theisen, F.M.3
  • 24
    • 62649090828 scopus 로고    scopus 로고
    • HTR2C gene polymorphisms and the metabolic syndrome in patients with schizophrenia: A replication study
    • Mulder H, Cohen D, Scheffer H, et al. HTR2C gene polymorphisms and the metabolic syndrome in patients with schizophrenia: a replication study. J Clin Psychopharmacol. 2009;1:16-20.
    • (2009) J Clin Psychopharmacol , vol.1 , pp. 16-20
    • Mulder, H.1    Cohen, D.2    Scheffer, H.3
  • 25
    • 0037097014 scopus 로고    scopus 로고
    • Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism
    • DOI 10.1016/S0140-6736(02)08913-4
    • Reynolds GP, Zhang ZJ, Zhang XB. Association of antipsychotic drug-induced weight gain with a 5-HT2C receptor gene polymorphism. Lancet. 2002;9323:2086-2087. (Pubitemid 34680975)
    • (2002) Lancet , vol.359 , Issue.9323 , pp. 2086-2087
    • Reynolds, G.P.1    Zhang, Z.-J.2    Zhang, X.-B.3
  • 26
    • 79959944606 scopus 로고    scopus 로고
    • Association of genetic variants of the histamine H1 and muscarinic M3 receptors with BMI and HbA1c values in patients on antipsychotic medication
    • Vehof J, Risselada AJ, Al Hadithy AF, et al. Association of genetic variants of the histamine H1 and muscarinic M3 receptors with BMI and HbA1c values in patients on antipsychotic medication. Psychopharmacology (Berl). 2011;2:257-265.
    • (2011) Psychopharmacology (Berl) , vol.2 , pp. 257-265
    • Vehof, J.1    Risselada, A.J.2    Al Hadithy, A.F.3
  • 27
    • 78649392014 scopus 로고    scopus 로고
    • Association between the 1291-C/G polymorphism in the adrenergic alpha-2a receptor and the metabolic syndrome
    • Risselada AJ, Vehof J, Bruggeman R, et al. Association between the 1291-C/G polymorphism in the adrenergic alpha-2a receptor and the metabolic syndrome. J Clin Psychopharmacol. 2010;6:667-671.
    • (2010) J Clin Psychopharmacol , vol.6 , pp. 667-671
    • Risselada, A.J.1    Vehof, J.2    Bruggeman, R.3
  • 28
    • 79954998186 scopus 로고    scopus 로고
    • Lipogenic effects of psychotropic drugs: Focus on the SREBP system
    • Ferno J, Skrede S, Vik-Mo AO, et al. Lipogenic effects of psychotropic drugs: focus on the SREBP system. Front Biosci. 2011;16:49-60.
    • (2011) Front Biosci , vol.16 , pp. 49-60
    • Ferno, J.1    Skrede, S.2    Vik-Mo, A.O.3
  • 29
    • 77957124138 scopus 로고    scopus 로고
    • Antipsychotic drugs up-regulate lipogenic gene expression by disrupting intracellular trafficking of lipoprotein-derived cholesterol
    • Kristiana I, Sharpe LJ, Catts VS, et al. Antipsychotic drugs up-regulate lipogenic gene expression by disrupting intracellular trafficking of lipoprotein-derived cholesterol. Pharmacogenomics J. 2009;5:396-407.
    • (2009) Pharmacogenomics J , vol.5 , pp. 396-407
    • Kristiana, I.1    Sharpe, L.J.2    Catts, V.S.3
  • 30
    • 56449085151 scopus 로고    scopus 로고
    • Association of antipsychotic induced weight gain and body mass index with GNB3 gene: A meta-analysis
    • Souza RP, De Luca V, Muscettola G, et al. Association of antipsychotic induced weight gain and body mass index with GNB3 gene: a meta-analysis. Prog Neuropsychopharmacol Biol Psychiatry. 2008;8:1848-1853.
    • (2008) Prog Neuropsychopharmacol Biol Psychiatry , vol.8 , pp. 1848-1853
    • Souza, R.P.1    De Luca, V.2    Muscettola, G.3
  • 31
    • 78649362142 scopus 로고    scopus 로고
    • Effect of FTO, SH2B1, LEP, and LEPR polymorphisms on weight gain associated with antipsychotic treatment
    • Perez-Iglesias R, Mata I, Amado JA, et al. Effect of FTO, SH2B1, LEP, and LEPR polymorphisms on weight gain associated with antipsychotic treatment. J Clin Psychopharmacol. 2010;6:661-666.
    • (2010) J Clin Psychopharmacol , vol.6 , pp. 661-666
    • Perez-Iglesias, R.1    Mata, I.2    Amado, J.A.3
  • 32
    • 77955055009 scopus 로고    scopus 로고
    • MTHFR and risk of metabolic syndrome in patients with schizophrenia
    • Van Winkel R, Rutten BP, Peerbooms O, et al. MTHFR and risk of metabolic syndrome in patients with schizophrenia. Schizophr Res. 2010;1-3:193-198.
    • (2010) Schizophr Res , vol.1-3 , pp. 193-198
    • Van Winkel, R.1    Rutten, B.P.2    Peerbooms, O.3
  • 33
    • 78951488004 scopus 로고    scopus 로고
    • Clock genes and body composition in patients with schizophrenia under treatment with antipsychotic drugs
    • Moons T, Claes S, Martens GJ, et al. Clock genes and body composition in patients with schizophrenia under treatment with antipsychotic drugs. Schizophr Res. 2011;2-3:187-193.
    • (2011) Schizophr Res , vol.2-3 , pp. 187-193
    • Moons, T.1    Claes, S.2    Martens, G.J.3
  • 34
    • 73349131110 scopus 로고    scopus 로고
    • The implication of CNR1 gene's polymorphisms in the modulation of endocannabinoid system effects
    • Dinu IR, Popa S, Bicu M, et al. The implication of CNR1 gene's polymorphisms in the modulation of endocannabinoid system effects. Rom J Intern Med. 2009;1:9-18.
    • (2009) Rom J Intern Med , vol.1 , pp. 9-18
    • Dinu, I.R.1    Popa, S.2    Bicu, M.3
  • 38
    • 79251486673 scopus 로고    scopus 로고
    • A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain
    • [serial online]. January Available at Accessed February 20 2012
    • Feng Q, Jiang L, Berg RL, et al. A common CNR1 (cannabinoid receptor 1) haplotype attenuates the decrease in HDL cholesterol that typically accompanies weight gain. PLoS One [serial online]. January 2011;12:e15779. Available at: http://www.plosone.org/article/info:doi%2F10.1371%2Fjournal.pone.0015779. Accessed February 20, 2012.
    • (2011) PLoS One , vol.12
    • Feng, Q.1    Jiang, L.2    Berg, R.L.3
  • 39
    • 50249131267 scopus 로고    scopus 로고
    • Cannabinoid type-1 receptor gene polymorphisms are associated with central obesity in a Southern Brazilian population
    • Jaeger JP, Mattevi VS, Callegari-Jacques SM, et al. Cannabinoid type-1 receptor gene polymorphisms are associated with central obesity in a Southern Brazilian population. Dis Markers. 2008;1:67-74.
    • (2008) Dis Markers , vol.1 , pp. 67-74
    • Jaeger, J.P.1    Mattevi, V.S.2    Callegari-Jacques, S.M.3
  • 41
    • 70349652046 scopus 로고    scopus 로고
    • Role of cannabis and endocannabinoids in the genesis of schizophrenia
    • Fernandez-Espejo E, Viveros MP, Nunez L, et al. Role of cannabis and endocannabinoids in the genesis of schizophrenia. Psychopharmacology (Berl). 2009;4:531-549.
    • (2009) Psychopharmacology (Berl) , vol.4 , pp. 531-549
    • Fernandez-Espejo, E.1    Viveros, M.P.2    Nunez, L.3
  • 42
    • 33845656373 scopus 로고    scopus 로고
    • The endocannabinoid system as a target for the treatment of visceral obesity and metabolic syndrome
    • DOI 10.1196/annals.1367.024, Stress, Obesity, and Metabolic Syndrome
    • Kyrou I, Valsamakis G, Tsigos C. The endocannabinoid system as a target for the treatment of visceral obesity and metabolic syndrome. Ann N Y Acad Sci. 2006;1083:270-305. (Pubitemid 44955478)
    • (2006) Annals of the New York Academy of Sciences , vol.1083 , pp. 270-305
    • Kyrou, I.1    Valsamakis, G.2    Tsigos, C.3
  • 44
    • 77954954279 scopus 로고    scopus 로고
    • Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C]OMAR
    • Wong DF, Kuwabara H, Horti AG, et al. Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C]OMAR. Neuroimage. 2010;4:1505-1513.
    • (2010) Neuroimage , vol.4 , pp. 1505-1513
    • Wong, D.F.1    Kuwabara, H.2    Horti, A.G.3
  • 45
    • 33847359549 scopus 로고    scopus 로고
    • Rimonabant: A novel selective cannabinoid-1 receptor antagonist for of treatment obesity
    • DOI 10.2146/060258
    • Patel PN, Pathak R. Rimonabant: a novel selective cannabinoid-1 receptor antagonist for treatment of obesity. Am J Health Syst Pharm. 2007;5:481-489. (Pubitemid 46339261)
    • (2007) American Journal of Health-System Pharmacy , vol.64 , Issue.5 , pp. 481-489
    • Patel, P.N.1    Pathak, R.2
  • 46
    • 80053276336 scopus 로고    scopus 로고
    • The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant's antiobesity effects in mice
    • Pang Z, Wu NN, Zhao W, et al. The central cannabinoid CB1 receptor is required for diet-induced obesity and rimonabant's antiobesity effects in mice. Obesity (Silver Spring). 2011;10:1923-1934.
    • (2011) Obesity (Silver Spring) , vol.10 , pp. 1923-1934
    • Pang, Z.1    Wu, N.N.2    Zhao, W.3
  • 47
    • 53749103705 scopus 로고    scopus 로고
    • Genetic variation may influence obesity only under conditions of diet: Analysis of three candidate genes
    • Aberle J, Flitsch J, Beck NA, et al. Genetic variation may influence obesity only under conditions of diet: analysis of three candidate genes. Mol Genet Metab. 2008;3:188-191.
    • (2008) Mol Genet Metab , vol.3 , pp. 188-191
    • Aberle, J.1    Flitsch, J.2    Beck, N.A.3
  • 48
    • 61549101858 scopus 로고    scopus 로고
    • Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass index
    • Baye TM, Zhang Y, Smith E, et al. Genetic variation in cannabinoid receptor 1 (CNR1) is associated with derangements in lipid homeostasis, independent of body mass index. Pharmacogenomics. 2008;11:1647-1656.
    • (2008) Pharmacogenomics , vol.11 , pp. 1647-1656
    • Baye, T.M.1    Zhang, Y.2    Smith, E.3
  • 50
    • 78751645595 scopus 로고    scopus 로고
    • Influence of G1359A polymorphism of the cannabinoid receptor gene on anthropometric parameters and insulin resistance in women with obesity
    • de Luis DA, Gonzalez Sagrado M, Aller R, et al. Influence of G1359A polymorphism of the cannabinoid receptor gene on anthropometric parameters and insulin resistance in women with obesity. Metabolism. 2011;2:272-276.
    • (2011) Metabolism , vol.2 , pp. 272-276
    • De Luis, D.A.1    Gonzalez Sagrado, M.2    Aller, R.3
  • 51
    • 79960187115 scopus 로고    scopus 로고
    • Relation of G1359A polymorphism of the cannabinoid receptor (CB1) gene with metabolic syndrome by ATP III classification
    • de Luis DA, Gonzalez Sagrado M, Aller R, et al. Relation of G1359A polymorphism of the cannabinoid receptor (CB1) gene with metabolic syndrome by ATP III classification. Diabetes Metab Res Rev. 2011;5:506-511.
    • (2011) Diabetes Metab Res Rev , vol.5 , pp. 506-511
    • De Luis, D.A.1    Gonzalez Sagrado, M.2    Aller, R.3
  • 52
    • 78049415493 scopus 로고    scopus 로고
    • A large-scale candidate gene association study of age at menarche and age at natural menopause
    • He C, Kraft P, Chasman DI, et al. A large-scale candidate gene association study of age at menarche and age at natural menopause. Hum Genet. 2010;5:515-527.
    • (2010) Hum Genet , vol.5 , pp. 515-527
    • He, C.1    Kraft, P.2    Chasman, D.I.3
  • 54
    • 77951098236 scopus 로고    scopus 로고
    • A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia
    • Tiwari AK, Zai CC, Likhodi O, et al. A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia. Neuropsychopharmacology. 2010;6:1315-1324.
    • (2010) Neuropsychopharmacology , vol.6 , pp. 1315-1324
    • Tiwari, A.K.1    Zai, C.C.2    Likhodi, O.3
  • 55
    • 77955129795 scopus 로고    scopus 로고
    • Endocannabinoid Pro129Thr FAAH functional polymorphism but not 1359G/A CNR1 polymorphism is associated with antipsychotic-induced weight gain
    • Monteleone P, Milano W, Petrella C, et al. Endocannabinoid Pro129Thr FAAH functional polymorphism but not 1359G/A CNR1 polymorphism is associated with antipsychotic-induced weight gain. J Clin Psychopharmacol. 2010;4:441-445.
    • (2010) J Clin Psychopharmacol , vol.4 , pp. 441-445
    • Monteleone, P.1    Milano, W.2    Petrella, C.3
  • 56
    • 79960835205 scopus 로고    scopus 로고
    • Cannabinoid type 1 receptor gene polymorphisms are not associated with olanzapine-induced weight gain
    • Park YM, Choi JE, Kang SG, et al. Cannabinoid type 1 receptor gene polymorphisms are not associated with olanzapine-induced weight gain. Hum Psychopharmacol. 2011;4-5:332-337.
    • (2011) Hum Psychopharmacol , vol.4-5 , pp. 332-337
    • Park, Y.M.1    Choi, J.E.2    Kang, S.G.3
  • 58
    • 33645409466 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome in patients with schizophrenia treated with antipsychotic medication
    • De Hert MA, van Winkel R, Van Eyck D, et al. Prevalence of the metabolic syndrome in patients with schizophrenia treated with antipsychotic medication. Schizophr Res. 2006;1:87-93.
    • (2006) Schizophr Res , vol.1 , pp. 87-93
    • De Hert, M.A.1    Van Winkel, R.2    Van Eyck, D.3
  • 59
    • 49649112948 scopus 로고    scopus 로고
    • Psychiatric diagnosis as an independent risk factor for metabolic disturbances: Results from a comprehensive, naturalistic screening program
    • van Winkel R, van Os J, Celic I, et al. Psychiatric diagnosis as an independent risk factor for metabolic disturbances: results from a comprehensive, naturalistic screening program. J Clin Psychiatry. 2008;8:1319-1327.
    • (2008) J Clin Psychiatry , vol.8 , pp. 1319-1327
    • Van Winkel, R.1    Van Os, J.2    Celic, I.3
  • 60
    • 79952006351 scopus 로고    scopus 로고
    • Effects of cannabis use on age at onset in schizophrenia and bipolar disorder
    • De Hert M, Wampers M, Jendricko T, et al. Effects of cannabis use on age at onset in schizophrenia and bipolar disorder. Schizophr Res. 2011;1-3:270-276.
    • (2011) Schizophr Res , vol.1-3 , pp. 270-276
    • De Hert, M.1    Wampers, M.2    Jendricko, T.3
  • 62
    • 40349084011 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes mellitus
    • American Diabetes Association
    • American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care. 2008;31:S55YS60.
    • (2008) Diabetes Care , vol.31
  • 63
    • 79951472497 scopus 로고    scopus 로고
    • Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: Sibling analysis and proband follow-up
    • van Winkel R. Family-based analysis of genetic variation underlying psychosis-inducing effects of cannabis: sibling analysis and proband follow-up. Arch Gen Psychiatry. 2011;68:148-157.
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 148-157
    • Van Winkel, R.1
  • 64
    • 70450235344 scopus 로고    scopus 로고
    • Recovering unused information in genome-wide association studies: The benefit of analyzing SNPs out of Hardy-Weinberg equilibrium
    • Fardo DW, Becker KD, Bertram L, et al. Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy-Weinberg equilibrium. Eur J Hum Genet. 2009;12:1676-1682.
    • (2009) Eur J Hum Genet , vol.12 , pp. 1676-1682
    • Fardo, D.W.1    Becker, K.D.2    Bertram, L.3
  • 65
    • 0008651450 scopus 로고    scopus 로고
    • Hardy-Weinberg equilibrium tests and allele frequency estimation
    • Cleves MA. Hardy-Weinberg equilibrium tests and allele frequency estimation. STATA Technical Bulletin. 1999;8:34-37.
    • (1999) STATA Technical Bulletin , vol.8 , pp. 34-37
    • Cleves, M.A.1
  • 66
    • 79952579297 scopus 로고    scopus 로고
    • Age at onset of psychotic disorder: Cannabis, BDNF Val66Met, and sex-specific models of gene-environment interaction
    • Decoster J, van Os J, Kenis G, et al. Age at onset of psychotic disorder: cannabis, BDNF Val66Met, and sex-specific models of gene-environment interaction. Am J Med Genet B Neuropsychiatr Genet. 2011;3:363-369.
    • (2011) Am J Med Genet B Neuropsychiatr Genet , vol.3 , pp. 363-369
    • Decoster, J.1    Van Os, J.2    Kenis, G.3
  • 67
    • 25144501575 scopus 로고    scopus 로고
    • Genetic association studies
    • DOI 10.1016/S0140-6736(05)67424-7, PII S0140673605674247
    • Cordell HJ, Clayton DG. Genetic association studies. Lancet. 2005;9491:1121-1131. (Pubitemid 41338767)
    • (2005) Lancet , vol.366 , Issue.9491 , pp. 1121-1131
    • Cordell, H.J.1    Clayton, D.G.2
  • 68
    • 77956270559 scopus 로고    scopus 로고
    • Polymorphisms in the endocannabinoid receptor 1 in relation to fat mass distribution
    • Frost M, Nielsen TL, Wraae K, et al. Polymorphisms in the endocannabinoid receptor 1 in relation to fat mass distribution. Eur J Endocrinol. 2010;3:407-412.
    • (2010) Eur J Endocrinol , vol.3 , pp. 407-412
    • Frost, M.1    Nielsen, T.L.2    Wraae, K.3
  • 69
    • 80955158245 scopus 로고    scopus 로고
    • Endocannabinoid type 1 receptor gene (CNR1) polymorphisms (rs806381, rs10485170, rs6454674, rs2023239) and cardiovascular risk factors in postmenopausal women
    • Laczmanski L, Milewicz A, Dunajska K, et al. Endocannabinoid type 1 receptor gene (CNR1) polymorphisms (rs806381, rs10485170, rs6454674, rs2023239) and cardiovascular risk factors in postmenopausal women. Gynecol Endocrinol. 2011;12:1023-1027.
    • (2011) Gynecol Endocrinol , vol.12 , pp. 1023-1027
    • Laczmanski, L.1    Milewicz, A.2    Dunajska, K.3
  • 70
    • 79952698829 scopus 로고    scopus 로고
    • Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women
    • Milewicz A, Tworowska-Bardzinska U, Jedrzejuk D, et al. Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women Int J Obes (Lond). 2011;3:373-377.
    • (2011) Int J Obes (Lond) , vol.3 , pp. 373-377
    • Milewicz, A.1    Tworowska-Bardzinska, U.2    Jedrzejuk, D.3
  • 71
    • 77956800047 scopus 로고    scopus 로고
    • G1359A polymorphism in the cannabinoid receptor-1 gene is associated with metabolic syndrome in the Chinese Han population
    • Hu WC, Feng P. G1359A polymorphism in the cannabinoid receptor-1 gene is associated with metabolic syndrome in the Chinese Han population. Arch Med Res. 2010;5:378-382.
    • (2010) Arch Med Res , vol.5 , pp. 378-382
    • Hu, W.C.1    Feng, P.2
  • 72
    • 84856481281 scopus 로고    scopus 로고
    • The role of the endocannabinoid system in the neuroendocrine regulation of energy balance
    • Bermudez-Silva FJ, Cardinal P, Cota D. The role of the endocannabinoid system in the neuroendocrine regulation of energy balance. J Psychopharmacol. 2012;26:1-11.
    • (2012) J Psychopharmacol , vol.26 , pp. 1-11
    • Bermudez-Silva, F.J.1    Cardinal, P.2    Cota, D.3
  • 73
    • 79955632246 scopus 로고    scopus 로고
    • Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes
    • Di Marzo V, Piscitelli F, Mechoulam R. Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes. Handb Exp Pharmacol. 2011;203:75-104.
    • (2011) Handb Exp Pharmacol , vol.203 , pp. 75-104
    • Di Marzo, V.1    Piscitelli, F.2    Mechoulam, R.3
  • 74
    • 51349153318 scopus 로고    scopus 로고
    • Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice
    • Osei-Hyiaman D, Liu J, Zhou L, et al. Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice. J Clin Invest. 2008;9:3160-3169.
    • (2008) J Clin Invest , vol.9 , pp. 3160-3169
    • Osei-Hyiaman, D.1    Liu, J.2    Zhou, L.3
  • 75
    • 84856414714 scopus 로고    scopus 로고
    • Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice
    • Bell-Anderson KS, Aouad L, Williams H, et al. Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice. Int J Obes (Lond). 2011;12:1539-1548.
    • (2011) Int J Obes (Lond) , vol.12 , pp. 1539-1548
    • Bell-Anderson, K.S.1    Aouad, L.2    Williams, H.3
  • 76
    • 48149101434 scopus 로고    scopus 로고
    • The endocannabinoid system in obesity and type 2 diabetes
    • Di Marzo V. The endocannabinoid system in obesity and type 2 diabetes. Diabetologia. 2008;8:1356-1367.
    • (2008) Diabetologia , vol.8 , pp. 1356-1367
    • Di Marzo, V.1
  • 77
    • 59649102201 scopus 로고    scopus 로고
    • Altered pattern of cannabinoid type 1 receptor expression in adipose tissue of dysmetabolic and overweight patients
    • Sarzani R, Bordicchia M, Marcucci P, et al. Altered pattern of cannabinoid type 1 receptor expression in adipose tissue of dysmetabolic and overweight patients. Metabolism. 2009;3:361-367.
    • (2009) Metabolism , vol.3 , pp. 361-367
    • Sarzani, R.1    Bordicchia, M.2    Marcucci, P.3
  • 80
    • 77954371737 scopus 로고    scopus 로고
    • Expression of cannabinoid CB1 receptors by vagal afferent neurons: Kinetics and role in influencing neurochemical phenotype
    • Burdyga G, Varro A, Dimaline R, et al. Expression of cannabinoid CB1 receptors by vagal afferent neurons: kinetics and role in influencing neurochemical phenotype. Am J PhysiolGastrointest Liver Physiol. 2010;1:63-69.
    • (2010) Am J PhysiolGastrointest Liver Physiol , vol.1 , pp. 63-69
    • Burdyga, G.1    Varro, A.2    Dimaline, R.3
  • 82
    • 33646856625 scopus 로고    scopus 로고
    • Ghrelin receptors in rat and human nodose ganglia: Putative role in regulating CB-1 and MCH receptor abundance
    • Burdyga G, Varro A, Dimaline R, et al. Ghrelin receptors in rat and human nodose ganglia: putative role in regulating CB-1 and MCH receptor abundance. Am J Physiol Gastrointest Liver Physiol. 2006;6:1289-1297.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.6 , pp. 1289-1297
    • Burdyga, G.1    Varro, A.2    Dimaline, R.3


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