메뉴 건너뛰기




Volumn 17, Issue 13, 2008, Pages 1916-1921

Endocannabinoid receptor 1 gene variations increase risk for obesity and modulate body mass index in European populations

Author keywords

[No Author keywords available]

Indexed keywords

ENDOCANNABINOID; ENDOCANNABINOID RECEPTOR 1;

EID: 45749158085     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddn089     Document Type: Article
Times cited : (89)

References (28)
  • 1
    • 0033998951 scopus 로고    scopus 로고
    • Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol
    • Hillard, C.J. (2000) Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. Prostaglandins Other Lipid Mediat., 61, 3-18.
    • (2000) Prostaglandins Other Lipid Mediat , vol.61 , pp. 3-18
    • Hillard, C.J.1
  • 5
    • 1842866963 scopus 로고    scopus 로고
    • CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity
    • Ravinet Trillou, C., Delgorge, C., Menet, C., Arnone, M. and Soubrie, P. (2004) CB1 cannabinoid receptor knockout in mice leads to leanness, resistance to diet-induced obesity and enhanced leptin sensitivity. Int. J. Obes. Relat. Metab. Disord., 28, 640-648.
    • (2004) Int. J. Obes. Relat. Metab. Disord , vol.28 , pp. 640-648
    • Ravinet Trillou, C.1    Delgorge, C.2    Menet, C.3    Arnone, M.4    Soubrie, P.5
  • 7
    • 23844482784 scopus 로고    scopus 로고
    • Cholesterol-dependent modulation of type 1 cannabinoid receptors in nerve cells
    • Bari, M., Paradisi, A., Pasquariello, N. and Maccarrone, M. (2005) Cholesterol-dependent modulation of type 1 cannabinoid receptors in nerve cells. J. Neurosci. Res., 81, 275-283.
    • (2005) J. Neurosci. Res , vol.81 , pp. 275-283
    • Bari, M.1    Paradisi, A.2    Pasquariello, N.3    Maccarrone, M.4
  • 9
    • 21344453761 scopus 로고    scopus 로고
    • The endocannabinoid system and the treatment of obesity
    • Pagotto, U., Vicennati, V. and Pasquali, R. (2005) The endocannabinoid system and the treatment of obesity. Ann. Med., 37, 270-275.
    • (2005) Ann. Med , vol.37 , pp. 270-275
    • Pagotto, U.1    Vicennati, V.2    Pasquali, R.3
  • 10
    • 32644441249 scopus 로고    scopus 로고
    • Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: A randomized controlled trial
    • Pi-Sunyer, F.X., Aronne, L.J., Heshmati, H.M., Devin, J. and Rosenstock, J. (2006) Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: A randomized controlled trial. Jama, 295, 761-775.
    • (2006) Jama , vol.295 , pp. 761-775
    • Pi-Sunyer, F.X.1    Aronne, L.J.2    Heshmati, H.M.3    Devin, J.4    Rosenstock, J.5
  • 11
    • 17144382751 scopus 로고    scopus 로고
    • Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
    • Van Gaal, L.F., Rissanen, A.M., Scheen, A.J., Ziegler, O. and Rossner, S. (2005) Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet, 365, 1389-1397.
    • (2005) Lancet , vol.365 , pp. 1389-1397
    • Van Gaal, L.F.1    Rissanen, A.M.2    Scheen, A.J.3    Ziegler, O.4    Rossner, S.5
  • 12
    • 33751001942 scopus 로고    scopus 로고
    • Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: A randomised controlled study
    • Scheen, A.J., Finer, N., Hollander, P., Jensen, M.D. and Van Gaal, L.F. (2006) Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: A randomised controlled study. Lancet 368, 1660-1672.
    • (2006) Lancet , vol.368 , pp. 1660-1672
    • Scheen, A.J.1    Finer, N.2    Hollander, P.3    Jensen, M.D.4    Van Gaal, L.F.5
  • 13
    • 27844463517 scopus 로고    scopus 로고
    • Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
    • Despres, J.P., Golay, A. and Sjostrom, L. (2005) Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N. Engl. J. Med., 353, 2121-2134.
    • (2005) N. Engl. J. Med , vol.353 , pp. 2121-2134
    • Despres, J.P.1    Golay, A.2    Sjostrom, L.3
  • 15
    • 35348858145 scopus 로고    scopus 로고
    • The G1422A variant of the cannabinoid receptor gene (CNR1) is associated with abdominal adiposity in obese men
    • Peeters, A., Beckers, S., Mertens, I., Van Hul, W. and Van Gaal, L. (2007) The G1422A variant of the cannabinoid receptor gene (CNR1) is associated with abdominal adiposity in obese men. Endocrine, 31 138-141.
    • (2007) Endocrine , vol.31 , pp. 138-141
    • Peeters, A.1    Beckers, S.2    Mertens, I.3    Van Hul, W.4    Van Gaal, L.5
  • 16
    • 34250002798 scopus 로고    scopus 로고
    • Genetic variation in two proteins of the endocannabinoid system and their influence on body mass index and metabolism under low fat diet
    • Aberle, J., Fedderwitz, I., Klages, N., George, E. and Beil, F.U. (2007) Genetic variation in two proteins of the endocannabinoid system and their influence on body mass index and metabolism under low fat diet. Horm. Metab. Res., 39, 395-397.
    • (2007) Horm. Metab. Res , vol.39 , pp. 395-397
    • Aberle, J.1    Fedderwitz, I.2    Klages, N.3    George, E.4    Beil, F.U.5
  • 18
    • 6044253601 scopus 로고    scopus 로고
    • Human cannabinoid receptor 1: 5′ exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse
    • Zhang, P.W., Ishiguro, H., Ohtsuki, T., Hess, J., Carillo, F., Walther, D., Onaivi, E.S., Arinami, T. and Uhl, G.R. (2004) Human cannabinoid receptor 1: 5′ exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse. Mol. Psychiatry 9, 916-931.
    • (2004) Mol. Psychiatry , vol.9 , pp. 916-931
    • Zhang, P.W.1    Ishiguro, H.2    Ohtsuki, T.3    Hess, J.4    Carillo, F.5    Walther, D.6    Onaivi, E.S.7    Arinami, T.8    Uhl, G.R.9
  • 19
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
    • Nyholt, D.R. (2004) A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am. J. Hum. Genet., 74, 765-769.
    • (2004) Am. J. Hum. Genet , vol.74 , pp. 765-769
    • Nyholt, D.R.1
  • 20
    • 30744434862 scopus 로고    scopus 로고
    • Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
    • Li, J. and Ji, L. (2005) Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix. Heredity, 95, 221-227.
    • (2005) Heredity , vol.95 , pp. 221-227
    • Li, J.1    Ji, L.2
  • 21
    • 33645511469 scopus 로고    scopus 로고
    • The unfolding cannabinoid story on energy homeostasis: Central or peripheral site of action?
    • Horvath, T.L. (2006) The unfolding cannabinoid story on energy homeostasis: Central or peripheral site of action? Int. J. Obes. (Lond), 30 (Suppl 1), S30-S32.
    • (2006) Int. J. Obes. (Lond) , vol.30 , Issue.SUPPL. 1
    • Horvath, T.L.1
  • 22
    • 0034471041 scopus 로고    scopus 로고
    • Obesity: Preventing and managing the global epidemic. Report of a WHO consultation
    • World Health Organ. Tech. Rep. Ser, 1-253
    • Horvath, T.L. (2000) Obesity: Preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ. Tech. Rep. Ser., 894, i-xii. 1-253.
    • (2000) , vol.894
    • Horvath, T.L.1
  • 24
    • 33745291825 scopus 로고    scopus 로고
    • The PPARG Pro 12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: The Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) study
    • Jaziri, R., Lobbens, S., Aubert, R., Pean, F., Lahmidi, S., Vaxillaire, M., Porchay, I., Bellili, N., Tichet, J., Balkau, B. et al. (2006) The PPARG Pro 12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: The Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR) study. Diabetes, 55, 1157-1162.
    • (2006) Diabetes , vol.55 , pp. 1157-1162
    • Jaziri, R.1    Lobbens, S.2    Aubert, R.3    Pean, F.4    Lahmidi, S.5    Vaxillaire, M.6    Porchay, I.7    Bellili, N.8    Tichet, J.9    Balkau, B.10
  • 25
    • 84960989652 scopus 로고
    • On estimating the relation between blood group and disease
    • Woolf, B. (1955) On estimating the relation between blood group and disease. Ann. Hum. Genet., 19, 251-253.
    • (1955) Ann. Hum. Genet , vol.19 , pp. 251-253
    • Woolf, B.1
  • 26
    • 0035884457 scopus 로고    scopus 로고
    • Exact inference for categorical data: Recent advances and continuing controversies
    • Agresti, A. (2001) Exact inference for categorical data: Recent advances and continuing controversies. Stat. Med., 20, 2709-2722.
    • (2001) Stat. Med , vol.20 , pp. 2709-2722
    • Agresti, A.1
  • 28
    • 0041857847 scopus 로고    scopus 로고
    • Pedigree disequilibrium tests for multilocus haplotypes
    • Dudbridge, F. (2003) Pedigree disequilibrium tests for multilocus haplotypes. Genet. Epidemiol., 25, 115-121.
    • (2003) Genet. Epidemiol , vol.25 , pp. 115-121
    • Dudbridge, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.