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Volumn 15, Issue 3, 2013, Pages 597-605

TRPV1 inhibition attenuates IL-13 mediated asthma features in mice by reducing airway epithelial injury

Author keywords

Airway epithelial injury; Asthma; Calpain; Calpain 10; IL 13; TRPV1

Indexed keywords

ALLERGEN; CALPAIN; CASPASE 3; CYTOCHROME C; INTERLEUKIN 23; MITOCHONDRIAL ENZYME; SMALL INTERFERING RNA; VANILLOID RECEPTOR 1;

EID: 84874938410     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.02.010     Document Type: Article
Times cited : (62)

References (50)
  • 3
    • 78650405313 scopus 로고    scopus 로고
    • Tralokinumab, an anti-IL-13 mAb for the potential treatment of asthma and COPD
    • G.M. Walsh Tralokinumab, an anti-IL-13 mAb for the potential treatment of asthma and COPD Curr Opin Investig Drugs 11 2010 1305 1312
    • (2010) Curr Opin Investig Drugs , vol.11 , pp. 1305-1312
    • Walsh, G.M.1
  • 5
    • 0342955715 scopus 로고    scopus 로고
    • Effect of the airway epithelium on the contraction of rat isolated trachea under conditions of low temperature
    • O. González, and G.E. Santacana Effect of the airway epithelium on the contraction of rat isolated trachea under conditions of low temperature Respiration 67 2000 439 443
    • (2000) Respiration , vol.67 , pp. 439-443
    • González, O.1    Santacana, G.E.2
  • 6
    • 0028959147 scopus 로고
    • Neurogenic switching: A hypothesis for a mechanism for shifting the site of inflammation in allergy and chemical sensitivity
    • W.J. Meggs Neurogenic switching: a hypothesis for a mechanism for shifting the site of inflammation in allergy and chemical sensitivity Environ Health Perspect 103 1995 54 56
    • (1995) Environ Health Perspect , vol.103 , pp. 54-56
    • Meggs, W.J.1
  • 7
    • 0023187773 scopus 로고
    • The site of the defect in asthma. Neurohumoral, mediator or smooth muscle?
    • A.E. Tattersfield The site of the defect in asthma. Neurohumoral, mediator or smooth muscle? Chest 91 1987 184S 189S
    • (1987) Chest , vol.91
    • Tattersfield, A.E.1
  • 8
    • 0027645736 scopus 로고
    • Neurogenic inflammation and sensitivity to environmental chemicals
    • W.J. Meggs Neurogenic inflammation and sensitivity to environmental chemicals Environ Health Perspect 101 1993 234 238
    • (1993) Environ Health Perspect , vol.101 , pp. 234-238
    • Meggs, W.J.1
  • 9
    • 9644269845 scopus 로고    scopus 로고
    • Increased expression of transient receptor potential vanilloid-1 in airway nerves of chronic cough
    • D.A. Groneberg, A. Niimi, Q.T. Dinh, B. Cosio, M. Hew, and A. Fischer Increased expression of transient receptor potential vanilloid-1 in airway nerves of chronic cough Am J Respir Crit Care Med 170 2004 1276 1280
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 1276-1280
    • Groneberg, D.A.1    Niimi, A.2    Dinh, Q.T.3    Cosio, B.4    Hew, M.5    Fischer, A.6
  • 10
    • 61649111137 scopus 로고    scopus 로고
    • TRPV1 receptors in sensitisation of cough and pain reflexes
    • J.J. Adcock TRPV1 receptors in sensitisation of cough and pain reflexes Pulm Pharmacol Ther 22 2009 65 70
    • (2009) Pulm Pharmacol Ther , vol.22 , pp. 65-70
    • Adcock, J.J.1
  • 11
    • 40149088458 scopus 로고    scopus 로고
    • TRPV1 antagonists as potential antitussive agents
    • R.L. McLeod, C.C. Correll, Y. Jia, and J.C. Anthes TRPV1 antagonists as potential antitussive agents Lung 186 2008 S59 S65
    • (2008) Lung , vol.186
    • McLeod, R.L.1    Correll, C.C.2    Jia, Y.3    Anthes, J.C.4
  • 12
    • 57749111494 scopus 로고    scopus 로고
    • Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control
    • B.F. Bessac, and S.E. Jordt Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control Physiology (Bethesda) 23 2008 360 370
    • (2008) Physiology (Bethesda) , vol.23 , pp. 360-370
    • Bessac, B.F.1    Jordt, S.E.2
  • 13
    • 78650877291 scopus 로고    scopus 로고
    • TRPV1 UTR-3 polymorphism and susceptibility of childhood asthma of the Han Nationality in Beijing
    • Q. Wang, X. Bai, D. Xu, D. Xu, H. Li, and J. Fang TRPV1 UTR-3 polymorphism and susceptibility of childhood asthma of the Han Nationality in Beijing Wei Sheng Yan Jiu 38 2009 516 521
    • (2009) Wei Sheng Yan Jiu , vol.38 , pp. 516-521
    • Wang, Q.1    Bai, X.2    Xu, D.3    Xu, D.4    Li, H.5    Fang, J.6
  • 14
    • 77956235414 scopus 로고    scopus 로고
    • Loss of function of transient receptor potential vanilloid 1 (TRPV1) genetic variant is associated with lower risk of active childhood asthma
    • G. Cantero-Recasens, J.R. Gonzalez, C. Fandos, E. Duran-Tauleria, L.A. Smit, and F. Kauffmann Loss of function of transient receptor potential vanilloid 1 (TRPV1) genetic variant is associated with lower risk of active childhood asthma J Biol Chem 285 2010 27532 27535
    • (2010) J Biol Chem , vol.285 , pp. 27532-27535
    • Cantero-Recasens, G.1    Gonzalez, J.R.2    Fandos, C.3    Duran-Tauleria, E.4    Smit, L.A.5    Kauffmann, F.6
  • 15
    • 46749091281 scopus 로고    scopus 로고
    • Cigarette smoke-induced neurogenic inflammation is mediated by alpha, beta-unsaturated aldehydes and the TRPA1 receptor in rodents
    • E. Andre, B. Campi, S. Materazzi, M. Trevisani, S. Amadesi, and D. Massi Cigarette smoke-induced neurogenic inflammation is mediated by alpha, beta-unsaturated aldehydes and the TRPA1 receptor in rodents J Clin Invest 118 2008 2574 2582
    • (2008) J Clin Invest , vol.118 , pp. 2574-2582
    • Andre, E.1    Campi, B.2    Materazzi, S.3    Trevisani, M.4    Amadesi, S.5    Massi, D.6
  • 16
    • 78649744386 scopus 로고    scopus 로고
    • Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents
    • R. Nassini, S. Materazzi, E. Andre, L. Sartiani, G. Aldini, and M. Trevisani Acetaminophen, via its reactive metabolite N-acetyl-p-benzo- quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents FASEB J 24 2010 4904 4916
    • (2010) FASEB J , vol.24 , pp. 4904-4916
    • Nassini, R.1    Materazzi, S.2    Andre, E.3    Sartiani, L.4    Aldini, G.5    Trevisani, M.6
  • 17
    • 0034669190 scopus 로고    scopus 로고
    • Vanilloid (capsaicin) receptors influence inflammatory sensitivity in response to particulate matter
    • B. Veronesi, M. Oortgiesen, J. Roy, J.D. Carter, S.A. Simon, and S.H. Gavett Vanilloid (capsaicin) receptors influence inflammatory sensitivity in response to particulate matter Toxicol Appl Pharmacol 169 2000 66 76
    • (2000) Toxicol Appl Pharmacol , vol.169 , pp. 66-76
    • Veronesi, B.1    Oortgiesen, M.2    Roy, J.3    Carter, J.D.4    Simon, S.A.5    Gavett, S.H.6
  • 18
    • 79955590047 scopus 로고    scopus 로고
    • The sensory receptor TRPV1 is expressed in human bronchial epithelium and upregulated in refractory (steroid resistant) asthma
    • C.A. Butler, S. McQuaid, T. Warke, M. Stevenson, L.G. Heaney, and L. McGarvey The sensory receptor TRPV1 is expressed in human bronchial epithelium and upregulated in refractory (steroid resistant) asthma Am J Respir Crit Care Med 181 2010 A2490
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 2490
    • Butler, C.A.1    McQuaid, S.2    Warke, T.3    Stevenson, M.4    Heaney, L.G.5    McGarvey, L.6
  • 19
    • 77649275723 scopus 로고    scopus 로고
    • Beneficial effects of high dose of l-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma
    • U. Mabalirajan, T. Ahmad, G.D. Leishangthem, D.A. Joseph, A.K. Dinda, and A. Agrawal Beneficial effects of high dose of l-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma J Allergy Clin Immunol 125 2010 626 635
    • (2010) J Allergy Clin Immunol , vol.125 , pp. 626-635
    • Mabalirajan, U.1    Ahmad, T.2    Leishangthem, G.D.3    Joseph, D.A.4    Dinda, A.K.5    Agrawal, A.6
  • 20
    • 84867005299 scopus 로고    scopus 로고
    • Resveratrol attenuates experimental allergic asthma in mice by restoring inositol polyphosphate 4 phosphatase (INPP4A)
    • J. Aich, U. Mabalirajan, T. Ahmad, K. Khanna, R. Rehman, and A. Agrawal Resveratrol attenuates experimental allergic asthma in mice by restoring inositol polyphosphate 4 phosphatase (INPP4A) Int Immunopharmacol 14 2012 438 443
    • (2012) Int Immunopharmacol , vol.14 , pp. 438-443
    • Aich, J.1    Mabalirajan, U.2    Ahmad, T.3    Khanna, K.4    Rehman, R.5    Agrawal, A.6
  • 21
    • 78651438299 scopus 로고    scopus 로고
    • Mepacrine treatment attenuates allergic airway remodeling segregated from airway inflammation in mice
    • T. Ahmad, U. Mabalirajan, K. Hasija, B. Ghosh, and A. Agrawal Mepacrine treatment attenuates allergic airway remodeling segregated from airway inflammation in mice Int Immunopharmacol 11 2011 74 78
    • (2011) Int Immunopharmacol , vol.11 , pp. 74-78
    • Ahmad, T.1    Mabalirajan, U.2    Hasija, K.3    Ghosh, B.4    Agrawal, A.5
  • 22
    • 51549106954 scopus 로고    scopus 로고
    • Mitochondrial structural changes and dysfunction are associated with experimental allergic asthma
    • U. Mabalirajan, A.K. Dinda, S. Kumar, R. Roshan, P. Gupta, and S.K. Sharma Mitochondrial structural changes and dysfunction are associated with experimental allergic asthma J Immunol 181 2008 3540 3548
    • (2008) J Immunol , vol.181 , pp. 3540-3548
    • Mabalirajan, U.1    Dinda, A.K.2    Kumar, S.3    Roshan, R.4    Gupta, P.5    Sharma, S.K.6
  • 23
    • 84863323038 scopus 로고    scopus 로고
    • Loss-of-function of inositol polyphosphate-4-phosphatase reversibly increases the severity of allergic airway inflammation
    • J. Aich, U. Mabalirajan, T. Ahmad, A. Agrawal, and B. Ghosh Loss-of-function of inositol polyphosphate-4-phosphatase reversibly increases the severity of allergic airway inflammation Nat Commun 3 2012 877
    • (2012) Nat Commun , vol.3 , pp. 877
    • Aich, J.1    Mabalirajan, U.2    Ahmad, T.3    Agrawal, A.4    Ghosh, B.5
  • 27
    • 33644806753 scopus 로고    scopus 로고
    • The transient receptor potential vanilloid 1: Role in airway inflammation and disease
    • P. Geppetti, S. Materazzi, and P. Nicoletti The transient receptor potential vanilloid 1: role in airway inflammation and disease Eur J Pharmacol 533 2006 207 214
    • (2006) Eur J Pharmacol , vol.533 , pp. 207-214
    • Geppetti, P.1    Materazzi, S.2    Nicoletti, P.3
  • 28
    • 84875721179 scopus 로고    scopus 로고
    • In vitro and in vivo assays for the discovery of analgesic drugs targeting TRP channels
    • M.X. Zhu, CRC Press Boca Raton (FL) [Chapter 18]
    • J. Chen, R.M. Reilly, P.R. Kym, and S. Joshi In vitro and in vivo assays for the discovery of analgesic drugs targeting TRP channels M.X. Zhu, Source TRP Channels 2011 CRC Press Boca Raton (FL) [Chapter 18]
    • (2011) Source TRP Channels
    • Chen, J.1    Reilly, R.M.2    Kym, P.R.3    Joshi, S.4
  • 29
    • 47749116508 scopus 로고    scopus 로고
    • TRPV1: A target for next generation analgesics
    • L.S. Premkumar, and P. Sikand TRPV1: a target for next generation analgesics Curr Neuropharmacol 6 2008 151 163
    • (2008) Curr Neuropharmacol , vol.6 , pp. 151-163
    • Premkumar, L.S.1    Sikand, P.2
  • 30
  • 31
    • 50649110931 scopus 로고    scopus 로고
    • 12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels
    • A.R. Hajek, A.R. Lindley, S. Favoreto Jr., R. Carter, R.P. Schleimer, and D.A. Kuperman 12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels J Allergy Clin Immunol 122 2008 633 639
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 633-639
    • Hajek, A.R.1    Lindley, A.R.2    Favoreto, Jr.S.3    Carter, R.4    Schleimer, R.P.5    Kuperman, D.A.6
  • 32
    • 70350117108 scopus 로고    scopus 로고
    • Effects of vitamin e on mitochondrial dysfunction and asthma features in an experimental allergic murine model
    • U. Mabalirajan, J. Aich, G.D. Leishangthem, S.K. Sharma, A.K. Dinda, and B. Ghosh Effects of vitamin E on mitochondrial dysfunction and asthma features in an experimental allergic murine model J Appl Physiol 107 2009 1285 1292
    • (2009) J Appl Physiol , vol.107 , pp. 1285-1292
    • Mabalirajan, U.1    Aich, J.2    Leishangthem, G.D.3    Sharma, S.K.4    Dinda, A.K.5    Ghosh, B.6
  • 33
    • 68149138511 scopus 로고    scopus 로고
    • Esculetin restores mitochondrial dysfunction and reduces allergic asthma features in experimental murine model
    • U. Mabalirajan, A.K. Dinda, S.K. Sharma, and B. Ghosh Esculetin restores mitochondrial dysfunction and reduces allergic asthma features in experimental murine model J Immunol 183 2009 2059 2067
    • (2009) J Immunol , vol.183 , pp. 2059-2067
    • Mabalirajan, U.1    Dinda, A.K.2    Sharma, S.K.3    Ghosh, B.4
  • 34
  • 35
    • 0029767839 scopus 로고    scopus 로고
    • Circulating nerve growth factor levels are increased in humans with allergic diseases and asthma
    • S. Bonini, A. Lambiase, S. Bonini, F. Angelucci, L. Magrini, and L. Manni Circulating nerve growth factor levels are increased in humans with allergic diseases and asthma Proc Natl Acad Sci U S A 9 1996 10955 10960
    • (1996) Proc Natl Acad Sci U S A , vol.9 , pp. 10955-10960
    • Bonini, S.1    Lambiase, A.2    Bonini, S.3    Angelucci, F.4    Magrini, L.5    Manni, L.6
  • 36
    • 29244484493 scopus 로고    scopus 로고
    • NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels
    • X. Zhang, J. Huang, and P.A. McNaughton NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels EMBO J 24 2005 4211 4223
    • (2005) EMBO J , vol.24 , pp. 4211-4223
    • Zhang, X.1    Huang, J.2    McNaughton, P.A.3
  • 37
  • 38
    • 0031684386 scopus 로고    scopus 로고
    • Role of nerve growth factor in a mouse model of allergic airway inflammation and asthma
    • A. Braun, E. Appel, R. Baruch, U. Herz, V. Botchkarev, and R. Paus Role of nerve growth factor in a mouse model of allergic airway inflammation and asthma Eur J Immunol 28 1998 3240 3251
    • (1998) Eur J Immunol , vol.28 , pp. 3240-3251
    • Braun, A.1    Appel, E.2    Baruch, R.3    Herz, U.4    Botchkarev, V.5    Paus, R.6
  • 40
    • 0035865095 scopus 로고    scopus 로고
    • IL-13 overexpression predisposes to anaphylaxis following antigen sensitization
    • P.G. Fallon, C.L. Emson, P. Smith, and A.N. McKenzie IL-13 overexpression predisposes to anaphylaxis following antigen sensitization J Immunol 166 2001 2712 2716
    • (2001) J Immunol , vol.166 , pp. 2712-2716
    • Fallon, P.G.1    Emson, C.L.2    Smith, P.3    McKenzie, A.N.4
  • 41
    • 79960987053 scopus 로고    scopus 로고
    • Identification of an IFN-γ/mast cell axis in a mouse model of chronic asthma
    • M. Yu, M.R. Eckart, A.A. Morgan, K. Mukai, A.J. Butte, and M. Tsai Identification of an IFN-γ/mast cell axis in a mouse model of chronic asthma J Clin Invest 121 2011 3133 3143
    • (2011) J Clin Invest , vol.121 , pp. 3133-3143
    • Yu, M.1    Eckart, M.R.2    Morgan, A.A.3    Mukai, K.4    Butte, A.J.5    Tsai, M.6
  • 42
    • 84855833033 scopus 로고    scopus 로고
    • MicroRNA-221 modulates RSV replication in human bronchial epithelium by targeting NGF expression
    • S. Othumpangat, C. Walton, and G. Piedimonte MicroRNA-221 modulates RSV replication in human bronchial epithelium by targeting NGF expression PLoS One 7 2012 e30030
    • (2012) PLoS One , vol.7 , pp. 30030
    • Othumpangat, S.1    Walton, C.2    Piedimonte, G.3
  • 43
    • 34250732324 scopus 로고    scopus 로고
    • P75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway
    • B.D. Sachs, G.S. Baillie, J.R. McCall, M.A. Passino, C. Schachtrup, and D.A. Wallace p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway J Cell Biol 177 2007 1119 1132
    • (2007) J Cell Biol , vol.177 , pp. 1119-1132
    • Sachs, B.D.1    Baillie, G.S.2    McCall, J.R.3    Passino, M.A.4    Schachtrup, C.5    Wallace, D.A.6
  • 45
    • 77649150074 scopus 로고    scopus 로고
    • The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress
    • G. Cantero-Recasens, C. Fandos, F. Rubio-Moscardo, M.A. Valverde, and R. Vicente The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress Hum Mol Genet 19 2010 111 121
    • (2010) Hum Mol Genet , vol.19 , pp. 111-121
    • Cantero-Recasens, G.1    Fandos, C.2    Rubio-Moscardo, F.3    Valverde, M.A.4    Vicente, R.5
  • 46
    • 42549118015 scopus 로고    scopus 로고
    • The TRPV1 receptor is associated with preferential stress in large dorsal root ganglion neurons in early diabetic sensory neuropathy
    • S. Hong, L. Agresta, C. Guo, and J.W. Wiley The TRPV1 receptor is associated with preferential stress in large dorsal root ganglion neurons in early diabetic sensory neuropathy J Neurochem 105 2008 1212 1222
    • (2008) J Neurochem , vol.105 , pp. 1212-1222
    • Hong, S.1    Agresta, L.2    Guo, C.3    Wiley, J.W.4
  • 47
    • 84860691114 scopus 로고    scopus 로고
    • The airway epithelium in asthma
    • B.N. Lambrecht, and H. Hammad The airway epithelium in asthma Nat Med 18 2012 684 692
    • (2012) Nat Med , vol.18 , pp. 684-692
    • Lambrecht, B.N.1    Hammad, H.2
  • 48
    • 84866534540 scopus 로고    scopus 로고
    • Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma
    • M. Suzukawa, H. Morita, A. Nambu, K. Arae, E. Shimura, and A. Shibui Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma J Immunol 189 2012 3641 3652
    • (2012) J Immunol , vol.189 , pp. 3641-3652
    • Suzukawa, M.1    Morita, H.2    Nambu, A.3    Arae, K.4    Shimura, E.5    Shibui, A.6
  • 49
    • 79551556034 scopus 로고    scopus 로고
    • Interleukin-33 in asthma: How big of a role does it play?
    • L. Borish, and J.W. Steinke Interleukin-33 in asthma: how big of a role does it play? Curr Allergy Asthma Rep 11 2011 7 11
    • (2011) Curr Allergy Asthma Rep , vol.11 , pp. 7-11
    • Borish, L.1    Steinke, J.W.2
  • 50
    • 75749149721 scopus 로고    scopus 로고
    • Thymic stromal lymphopoietin
    • R. He, and R.S. Geha Thymic stromal lymphopoietin Ann N Y Acad Sci 1183 2010 13 24
    • (2010) Ann N y Acad Sci , vol.1183 , pp. 13-24
    • He, R.1    Geha, R.S.2


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