ATP-P2X4 signaling mediates NLRP3 inflammasome activation: A novel pathway of diabetic nephropathy

International Journal of Biochemistry and Cell Biology

Volumn 45, Issue 5, 2013, Pages 932-943

  Chen, Kehong ^a   Zhang, Jianguo ^a   Zhang, Weiwei ^a   Zhang, Jinhua ^a   Yang, Jurong ^a   Li, Kailong ^a   He, Yani ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Diabetic nephropathy; Extracellular ATP; NLRP3 inflammasome; P2X4; Tubulointerstitial inflammation

Indexed keywords

ADENOSINE TRIPHOSPHATE; APYRASE; CRYOPYRIN; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PURINERGIC P2X4 RECEPTOR; SURAMIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DIABETIC NEPHROPATHY; EX VIVO STUDY; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; INTERSTITIAL NEPHRITIS; KIDNEY INTERSTITIUM; KIDNEY TUBULE EPITHELIUM; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; ADULT; AGED; CARRIER PROTEINS; CELL CULTURE TECHNIQUES; DIABETES MELLITUS, TYPE 2; DIABETIC NEPHROPATHIES; FEMALE; GLUCOSE; HUMANS; INFLAMMASOMES; MALE; MIDDLE AGED; NEPHRITIS, INTERSTITIAL; RECEPTORS, PURINERGIC P2X4; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84874930374     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2013.02.009     Document Type: Article

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