GADD45α Induction by Nickel Negatively Regulates JNKs/p38 Activation via Promoting PP2Cα Expression

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Yu, Yonghui ^a,b   Li, Jingxia ^a   Wan, Yu ^b   Lu, Jianyi ^c   Gao, Jimin ^c   Huang, Chuanshu ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WUHAN UNIVERSITY   (China)

^c WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE P38; NICKEL; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2CALPHA; PROTEIN C JUN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE DELETION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN INDUCTION; UPREGULATION;

ANIMALS; CELL CYCLE PROTEINS; CELL LINE; ENZYME ACTIVATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HCT116 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NICKEL; NUCLEAR PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEIN PHOSPHATASES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 84874831156     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057185     Document Type: Article

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