Activation of nuclear factor-κB and not activator protein-1 in cellular response to nickel compounds

Environmental Health Perspectives

Volumn 110, Issue SUPPL. 5, 2002, Pages 835-839

  Huang, Yi ^a   Davidson, Gerard ^a   Li, Jiangxia ^a   Yan, Yan ^a   Chen, Fei ^a   Costa, Max ^a   Chen, Lung Chi ^a   Huang, Chuanshu ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AP 1; NF B; Nickel compounds

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICKEL; NICKEL CHLORIDE; NICKEL SULFATE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TUMOR PROMOTER;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL STRAIN 3T3; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; EPIDERMIS CELL; INHALATION; LUNG CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSACTIVATION;

ANIMALIA;

EID: 0036804941     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.02110s5835     Document Type: Article

References (67)

1. Greenwood NN, Earnshaw A. Chemistry of the Elements. Oxford: Pergamon Press, 1994.
2. Bennett BG. Environmental nickel pathways to man. IARC Scientific Publication No. 53. Lyon:International Agency for Research on Cancer, 1984.
3. Shen HM, Zhang QF. Risk assessment of nickel carcinogenicity and occupational lung cancer. Environ Health Perspect 102:275-282 (1994).
4. Langard S. Nickel-related cancer in welders. Sci Total Environ 148:303-309 (1994).
5. Sunderman FW, Donnelly AJ. Studies of nickel carcinogenesis metatasizing pulmonary tumors in rats induced by inhalation of nickel carbonyl. Am J Pathol 46:1027-1042 (1965).
6. Ottolenghi AD, Haseman JK, Payne WW, Falk HL, Macfarland HN. Inhalation studies of nickel sulfide in pulmonary carcinogenesis of rats. J Natl Cancer Inst 54:1165-1172 (1975).
7. Sunderman FW. Recent research on nickel carcinogenesis. Environ Health Perspect 40:131-141 (1981).
8. Sunderman FW. Mechanisms of nickel carcinogenesis. Scand J Work Environ Health 15:1-12 (1989).
9. Costa M. Molecular mechanisms of nickel carcinogenesis. Annu Rev Pharmacol Toxicol 31:321-337 (1991).
10. Costa M. Molecular mechanisms of nickel carcinogenesis. Toxicol Environ Chem 49:145-148 (1995).
11. Snow ET. Metal carcinogenesis: mechanistic implications. Pharmacol Ther 53:31-65 (1992).
12. Costa M. Mechanisms of nickel genotoxicity an carcinogenicity. In: Toxicology of Metals (Chang LW, ed). Boca Raton, FL:CRC Press, 1996;245-251.
13. Flessel CP. Metal as mutagens. In: Inorganic and Nutritional Aspects of Cancer (Schrauzer GN, ed). New York:Plenum, 1978;117-128.
14. Fletcher GG, Rossetto FE, Turnbull JD, Nieboer E. Toxicity, uptake, and mutagenicity of particulate and soluble nickel compounds. Environ Health Perspect 102:69-79 (1994).
15. Kargacin B, Klein CB, Costa M. Mutagenic responses of nickel oxides and nickel sulfides in Chinese hamster V79 cell lines at the xanthine-guanine phosphoribosyl transferase locus. Mutat Res 300:63-72 (1993).
16. Morita H, Umeda M. Ogawa HI. Mutagenicity of various chemicals including nickel and cobalt compounds in cultured mouse FM3A cells. Mutat Res 261:131-137 (1991).
17. Epner DE, Herschman HR, Heavy-metals induce expression of the TPA-inducible sequence (TIS) genes. J Cell Physiol 148:68-74 (1991).
18. Bauman JW, Liu J, Klaassen CD. Production of metallothionein and heat-shock proteins in response to metals. Fundam Appl Toxicol 21:15-22 (1993).
19. Yiangou M, Ge X, Carter KC, Papaconstantinou J. Induction of several acute-phase protein genes by heavy metals- a new class of metal-responsive genes. Biochemistry 30:3798-3806 (1991).
20. Sen R, Baltimore D. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 46:705-716 (1986).
21. Sen R. Baltimore D. Inducibility of kappa immunoglobulin enhancer-binding protein NF-ΚB by a posttranslational mechanism. Cell 47:921-928 (1986).
22. Siebenlist U, Franzoso G, Brown K. Structure, regulation and function of NF-κB. Annu Rev Cell Biol 10:405-455 (1994).
23. Baeuerle PA, Baltimore D. NF-κB: ten years after. Cell 87:13-20 (1996).
24. Baldwin AS. The NF-κB and IκB proteins: new discoveries and insights. Annu Rev Immunol 14:649-683 (1996).
25. Li JJ, Westergaard C, Ghosh P, Colburn NH. Inhibitors of both nuclear factor-κB and activator protein-1 activation block the neoplastic transformation response. Cancer Res 57:3569-3576 (1997).
26. Wu H, Lozano G. NF-κB activation of p53. A potential mechanism for supressing cell growth in response to stress. J Biol Chem 269:20067-20074 (1994).
27. Angel P, Karin M. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1072:129-157 (1991).
28. Karin M. The regulation of AP-1 activity by mitogen-activated protein kinases. J Biol Chem 270:16483-16486 (1995).
29. Davis RJ. MAPKS: new JNK expands the group. Trends Biochem Sci 19:470-473 (1994).
30. Bernstein LR, Colburn NH. AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells. Science 244:566-569 (1989).
31. Angel P, Imagawa M, Chiu R, Stein B, Imbra RJ, Rahmsdorf HJ, Jonat C, Herrlich P, Karin M. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 49:729-739 (1987).
32. Lee W, Haslinger A, Karin M, Tijian B. Activation of transcription by two factors that bind promoter and enchancer sequences of the human metallothionein gene. Nature (London) 325:368-372 (1987).
33. Huang C, Zhang Q, Li J, Shi X, Castranova V, Ju G, Costa M, Dong Z. Involvement of Erks activation in cadmium-induced AP-1 transactivation in vitro and in vivo. Mol Cell Biochem 222:141-147 (2001).
34. Huang C, Ma W-Y, Bowden GT, Dong Z. Ultraviolet B-induced activated protein-1 activation does not require epidermal growth factor receptor but is blocked by a dominant negative PKCλ/ι. J Biol Chem 49:31262-31268 (1996).
35. Huang C, Chen N, Ma W-Y, Dong Z, Vanadium induces AP-1 and NFκB-dependent transcription activity. Int J Oncol 13:711-715 (1998).
36. Huang C, Ma WY, Li J, Dong Z. Arsenic induces apoptosis through a c-Jun NH2-terminal kinase-dependent, p53-independent pathway. Cancer Res 59:3053-3058 (1999).
37. Chen F, Lu Y, Zhang Z, Vallyathan V, Ding M, Castranova V, Shi X. Opposite effect of NF-κB and c-Jun N-terminal kinase on p53-independent GADD45 induction by arsenite. J Biol Chem 276:11414-11419 (2001).
38. Huang C, Ma WY, Young MR, Colburn N, Dong Z. Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells. Proc Natl Acad Sci USA 95:156-161 (1998).
39. Huang C, Li J, Costa M, Zhang Z, Leonard SS, Castranova V, Vallyathan V, Ju G, Shi X. Hydrogen peroxide mediates activation of nuclear of activation T cell (NFAT) by nickel subsulfide. Cancer Res 61:8051-8057 (2001).
40. 2+ compounds. Cancer Res 58:2182-2189 (1998).
41. 2+ exposure. In: Metals and Genetics (Sarkar B, ed). New York:Kluwer Academic/Plenum Publisher, 1999;131-144.
42. Cangul H, Salikow K, Yee H, Zagzag D, Commes T, Costa M. Enchanced overexpression of an HIF-1/hypoxia-related protein in cancer cells. Environ Health Perspect 110(suppl 5): 783-788 (2002).
43. Costa M, Sutherland JE, Peng W, Salnikow K, Broday L Kluz T. Molecular biology of nickel carcinogenesis. Mol Cell Biochem 222:205-211 (2001).
44. Baeuerle PA, Baltimore D. Function and activation of NF-κB in the immune systems. Annu Rev Immunol 12:141-179 (1994).
45. Liou HC, Baltimore D. Regulation of the NF-κB/Rel transcripstion factor and LκB inhibitor system. Curr Opin Cell Biol 5:477-487 (1993).
46. Grilli M, Jason JS, Lenardo M. NF-κB and Rel-participants in a multiform transcriptional regulatroy systems. Int Rev Cytol 143:1-62 (1993).
47. Israel A. A role for phosphorylation and degradation in the control of NF-κB activity. Trends Genet 11:203-205 (1995).
48. Beg AA, Baldwin AS. The I-κB proteins: multifunctional regulators of Rel/NF-κB transciption factors. Gene Dev 7:2064-2070 (1993).
49. Gilmore TD, Morin P. The IκB proteins: member of a multifunctional family. Trends Genet 9:427-433(1993).
50. Miyamoto S, Verma IM. Rel/NF-κB/LκB story. Adv Cancer Res 66:255-292 (1995).
51. Finco TS, Baldwin AS. Regulation of NF-κB: the emerging roles of phosphorylation and proteolysis. Immunity 3:263-272 (1995).
52. Palombella VJ, Rando OJ, Goldberg AL, Maniatis T. The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB. Cell 78:773-785 (1994).
53. Traenckner EB, Baeuerle PA. A proteasome inhibitor prevents activation of NF-κB and stabilizes a newly phosphorylated form of IκB-α that is still bound to NF-κB. EMBO J 13:5433-5441 (1994).
54. Miyamoto S, Maki M, Schmitt MJ, Hatanaka M, Verma IM. Tumor necrosis factor-α-induced phosphorylation of IκBα is a signal for its degradation but not dissociation from NF-κB. Proc Natl Acad Sci USA 91:12740-12744 (1994).
55. Gilmore TD, Koedood M, Piffat KA, White DW. Rel/NF-κB/lκB proteins and cancer. Oncogene 13:1367-1378 (1996).
56. Lin J, Arcinas M, Boxer LM. NF-κB sites function as positive regulators of expression of the translocated c-myc allele in Burkitt's lymphoma. Mol Cell Biol 14:7967-7974 (1994).
57. Finco TS, Westwick JK, Norris JL, Beg AA, Der CJ, Baldwin AS. Oncogenic Ha-Ras-induced signaling activates NF-κB transcriptional activity, which is required for cellular transformation. J Biol Chem 272:24113-24116 (1997).
58. Dong Z, Birrer MJ, Watts RG, Matrisian LM, Colburn NH. Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells. Proc Natl Acad Sci USA 91:609-613 (1994).
59. Dong Z, Watts RG, Sun Y, Colburn NH. Progressive elevation of AP-1 activity during preneoplastic progression as modelled in mouse JB6 cell variants. Int J Oncol 7:359-364 (1995).
60. Huang C, Ma WY, Hecht SS, Dong Z. Inositol hexaphosphate inhibits cell transformation and activator protein 1 activation by targeting phosphtidylinositol-3′ kinase. Cancer Res 57:2873-2878 (1997).
61. + cells. Mol Cell Biol 16:6427-6435 (1996).
62. Huang C, Ma W-Y, Dong Z. Inhibitory effects of ascorbic acid on AP-1 activity and transformation in JB6 cells. Int J Oncol 8:389-393 (1996).
63. Huang C, Li J, Ma MY, Dong Z. JNK activation is required for JB6 cell transformation induced by TNF-α but not by 12-O-tetradecanoylphorbol-13-acetate. J Biol Chem 274:29672-29676 (1999).
64. Watts RG, Huang C, Young MR, Li JJ, Dong Z, Pennie WD, Colburn NH. Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation. Oncogene 17:3493-3498 (1998).
65. Cohen DR, Curran T. Fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen. Mol Cell Biol 8:2063-2069 (1987).
66. Huang C, Ma WY, Dawson MI, Rincon M, Flavell RA, Dong Z. Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid. Proc Natl Acad Sci USA 94:5826-5830 (1997).
67. Salnikow K, Blagosklonny MV, Ryan H, Johnson R, Costa M. Carcinogenic nickel induces genes involved with hypoxic stress. Cancer Res 60:38-41 (2000).