-
2
-
-
80155201353
-
The cystine signature and molecular-recognition processes of the vascular endothelial growth factor family of angiogenic cytokines
-
Iyer S, Acharya KR, (2011) The cystine signature and molecular-recognition processes of the vascular endothelial growth factor family of angiogenic cytokines. FEBS J. 278: 4304-4322.
-
(2011)
FEBS J.
, vol.278
, pp. 4304-4322
-
-
Iyer, S.1
Acharya, K.R.2
-
3
-
-
0025986121
-
New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor
-
McDonald NQ, Lapatto R, Murray-Rust J, Gunning J, Wlodawer A, et al. (1991) New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor. Nature 354: 411-4.
-
(1991)
Nature
, vol.354
, pp. 411-414
-
-
McDonald, N.Q.1
Lapatto, R.2
Murray-Rust, J.3
Gunning, J.4
Wlodawer, A.5
-
4
-
-
0027918158
-
Topological similarities in TGF-beta 2, PDGF-BB and NGF define a superfamily of polypeptide growth factors
-
Murray-Rust J, McDonald NQ, Blundell TL, Hosang M, Oefner C, et al. (1993) Topological similarities in TGF-beta 2, PDGF-BB and NGF define a superfamily of polypeptide growth factors. Structure 1: 153-159.
-
(1993)
Structure
, vol.1
, pp. 153-159
-
-
Murray-Rust, J.1
McDonald, N.Q.2
Blundell, T.L.3
Hosang, M.4
Oefner, C.5
-
5
-
-
2442715239
-
Thermal, Chemical, and Enzymatic Stability of the Cyclotide Kalata B1: The Importance of the Cyclic Cystine Knot Biochemistry
-
Colgrave ML, Craik DJ, (2004) Thermal, Chemical, and Enzymatic Stability of the Cyclotide Kalata B1: The Importance of the Cyclic Cystine Knot Biochemistry. 43: 5965-5975.
-
(2004)
, vol.43
, pp. 5965-5975
-
-
Colgrave, M.L.1
Craik, D.J.2
-
6
-
-
0033582942
-
Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution
-
Scheufler C, Sebald W, Hulsmeyer M, (1999) Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution. J Mol Biol 287: 103-115.
-
(1999)
J Mol Biol
, vol.287
, pp. 103-115
-
-
Scheufler, C.1
Sebald, W.2
Hulsmeyer, M.3
-
7
-
-
0035010433
-
Evolution and Classification of Cystine Knot-Containing Hormones and Related Extracellular Signaling Molecules Molecular Endocrinology
-
Vitt UA, Hsu SY, Hsueh AJW, (2001) Evolution and Classification of Cystine Knot-Containing Hormones and Related Extracellular Signaling Molecules Molecular Endocrinology. 15(5): 681-694.
-
(2001)
, vol.15
, Issue.5
, pp. 681-694
-
-
Vitt, U.A.1
Hsu, S.Y.2
Hsueh, A.J.W.3
-
8
-
-
84862762318
-
Promiscuity and specificity in BMP receptor activation FEBS Lett
-
Mueller TD, Nickel J, (2012) Promiscuity and specificity in BMP receptor activation FEBS Lett. 586: 1846-1859.
-
(2012)
, vol.586
, pp. 1846-1859
-
-
Mueller, T.D.1
Nickel, J.2
-
9
-
-
0032852528
-
Molecular and biological properties of vascular endothelial growth factor J Mol Med
-
Ferrara N, (1999) Molecular and biological properties of vascular endothelial growth factor J Mol Med. 77: 527-543.
-
(1999)
, vol.77
, pp. 527-543
-
-
Ferrara, N.1
-
10
-
-
0035395760
-
Role of the cystine-knot motif at the C-terminus of rat mucin protein Muc2 in dimer formation and secretion Biochem J
-
Bell SL, Xu G, Forstner JF, (2001) Role of the cystine-knot motif at the C-terminus of rat mucin protein Muc2 in dimer formation and secretion Biochem J. 357: 203-209.
-
(2001)
, vol.357
, pp. 203-209
-
-
Bell, S.L.1
Xu, G.2
Forstner, J.F.3
-
12
-
-
0003880161
-
-
New York, NY, Garland Science
-
Alberts B, Johnson A, Lewis J, Raff M, Roberts K, et al. (2002) Molecular Biology of the Cell New York, NY, Garland Science.
-
(2002)
Molecular Biology of the Cell
-
-
Alberts, B.1
Johnson, A.2
Lewis, J.3
Raff, M.4
Roberts, K.5
-
13
-
-
70349314644
-
Stem cells, microenvironment mechanics, and growth factor activation Current Opinion in Cell Biology
-
Tenney RM, Discher D, (2009) Stem cells, microenvironment mechanics, and growth factor activation Current Opinion in Cell Biology. 21: 630-635.
-
(2009)
, vol.21
, pp. 630-635
-
-
Tenney, R.M.1
Discher, D.2
-
14
-
-
73549110486
-
Mechanical Strength of 17 134 Model Proteins and Cysteine Slipknots
-
Sikora M, Su lkowska JI, Cieplak M, (2009) Mechanical Strength of 17 134 Model Proteins and Cysteine Slipknots. PLoS Comp Biol 5: e1000547.
-
(2009)
PLoS Comp Biol
, vol.5
-
-
Sikora, M.1
Su lkowska, J.I.2
Cieplak, M.3
-
15
-
-
79952096460
-
Molecular jamming - the cysteine slipknot mechanical clamp in all-atom simulations
-
Peplowski L, Sikora M, Nowak W, Cieplak M, (2011) Molecular jamming - the cysteine slipknot mechanical clamp in all-atom simulations. J Chem Phys 134: 085102.
-
(2011)
J Chem Phys
, vol.134
, pp. 085102
-
-
Peplowski, L.1
Sikora, M.2
Nowak, W.3
Cieplak, M.4
-
16
-
-
0034533671
-
Mechanical design of proteins studied by single-molecule force spectroscopy and protein engineering
-
Carrion-Vazquez M, Oberhauser AF, Fisher TE, Marszalek PE, Li H, et al. (2000) Mechanical design of proteins studied by single-molecule force spectroscopy and protein engineering. Prog Biophys Mol Biol 74: 63-91.
-
(2000)
Prog Biophys Mol Biol
, vol.74
, pp. 63-91
-
-
Carrion-Vazquez, M.1
Oberhauser, A.F.2
Fisher, T.E.3
Marszalek, P.E.4
Li, H.5
-
17
-
-
0033548611
-
How strong is a covalent bond?
-
Grandbois M, Beyer M, Rief M, Clausen-Schaumann H, Gaub HE, (1999) How strong is a covalent bond? Science 283: 1727-1730.
-
(1999)
Science
, vol.283
, pp. 1727-1730
-
-
Grandbois, M.1
Beyer, M.2
Rief, M.3
Clausen-Schaumann, H.4
Gaub, H.E.5
-
18
-
-
41449084585
-
Dynamic strength of the siliconcarbon bond observed over three decades of force-loading rates
-
Schmidt SW, Beyer MK, Clausen-Schaumann H, (2008) Dynamic strength of the siliconcarbon bond observed over three decades of force-loading rates. J Am Chem Soc 130: 3664-3668.
-
(2008)
J Am Chem Soc
, vol.130
, pp. 3664-3668
-
-
Schmidt, S.W.1
Beyer, M.K.2
Clausen-Schaumann, H.3
-
19
-
-
0038206538
-
Molecular nanosprings in spider capture-silk threads
-
Becker N, Oroudjev E, Mutz S, Cleveland JP, Hansma PK, et al. (2003) Molecular nanosprings in spider capture-silk threads. Nature Mat 2: 278-283.
-
(2003)
Nature Mat
, vol.2
, pp. 278-283
-
-
Becker, N.1
Oroudjev, E.2
Mutz, S.3
Cleveland, J.P.4
Hansma, P.K.5
-
20
-
-
77955983405
-
Unravelling the design principles for single protein mechanical strength
-
Crampton N, Brockwell DJ, (2010) Unravelling the design principles for single protein mechanical strength. Curr Opin Struct Biol 20: 508-517.
-
(2010)
Curr Opin Struct Biol
, vol.20
, pp. 508-517
-
-
Crampton, N.1
Brockwell, D.J.2
-
21
-
-
77949317269
-
Understanding biology by stretching proteins: recent progress
-
Galera-Prat A, Gomez-Sicilia A, Oberhauser AF, Cieplak M, Carrion-Vazquez M, (2010) Understanding biology by stretching proteins: recent progress. Curr Opin Struct Biol 20: 63-69.
-
(2010)
Curr Opin Struct Biol
, vol.20
, pp. 63-69
-
-
Galera-Prat, A.1
Gomez-Sicilia, A.2
Oberhauser, A.F.3
Cieplak, M.4
Carrion-Vazquez, M.5
-
23
-
-
84863470496
-
Mechanically untying a protein slipknot: Multiple pathways revealed by force spectroscopy and steered molecular dynamics
-
He C, Genchev GZ, Lu H, Li H, (2012) Mechanically untying a protein slipknot: Multiple pathways revealed by force spectroscopy and steered molecular dynamics. J Am Chem Soc 134: 10428-10435.
-
(2012)
J Am Chem Soc
, vol.134
, pp. 10428-10435
-
-
He, C.1
Genchev, G.Z.2
Lu, H.3
Li, H.4
-
24
-
-
0033954256
-
The Protein Data Bank
-
Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, et al. (2000) The Protein Data Bank. Nucl Acids Res 28: 235-242.
-
(2000)
Nucl Acids Res
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
-
25
-
-
33644846751
-
Mechanical strength of the titin Z1Z2-telethonin complex
-
Lee EH, Gao M, Pinotsis N, Wilmanns M, Schulten K, (2006) Mechanical strength of the titin Z1Z2-telethonin complex. Structure 14: 497-509.
-
(2006)
Structure
, vol.14
, pp. 497-509
-
-
Lee, E.H.1
Gao, M.2
Pinotsis, N.3
Wilmanns, M.4
Schulten, K.5
-
26
-
-
69449083856
-
The titin-telethonin complex is a directed, superstable molecular bond in the muscle Z-disk
-
Bertz M, Wilmanns M, Rief M, (2009) The titin-telethonin complex is a directed, superstable molecular bond in the muscle Z-disk. Proc natl Acad Sci USA 106: 13307-13310.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 13307-13310
-
-
Bertz, M.1
Wilmanns, M.2
Rief, M.3
-
27
-
-
79955724209
-
Proteins: Struct Funct Bioinf
-
Sikora M, Cieplak M, (2011) Proteins: Struct Funct Bioinf. 79: 1786.
-
(2011)
, vol.79
, pp. 1786
-
-
Sikora, M.1
Cieplak, M.2
-
28
-
-
0035069135
-
Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping
-
Janowski R, Kozak M, Janowska E, Grzonka Z, Grubb A, et al. (2001) Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping. Nat Struct Biol 8: 316-320.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 316-320
-
-
Janowski, R.1
Kozak, M.2
Janowska, E.3
Grzonka, Z.4
Grubb, A.5
-
29
-
-
38749091363
-
KNOTTIN: the knottin or inhibitor cystine knot scaffold.Nucl Acid Res
-
Gracy J, Le-Nguyen D, Gelly JC, Kaas Q, Heitz A, et al. (2008) KNOTTIN: the knottin or inhibitor cystine knot scaffold.Nucl Acid Res. 36: D314-319.
-
(2008)
, vol.36
-
-
Gracy, J.1
Le-Nguyen, D.2
Gelly, J.C.3
Kaas, Q.4
Heitz, A.5
-
30
-
-
3042806394
-
Thermal effects in stretching of Go-like models of titin and secondary structures
-
Cieplak M, Hoang TX, Robbins MO, (2004) Thermal effects in stretching of Go-like models of titin and secondary structures. Proteins: Struct Funct Bio 56: 285-297.
-
(2004)
Proteins: Struct Funct Bio
, vol.56
, pp. 285-297
-
-
Cieplak, M.1
Hoang, T.X.2
Robbins, M.O.3
-
31
-
-
34547673274
-
Mechanical stretching of proteins - a theoretical survey of the Protein Data Bank
-
Su lkowska JI, Cieplak M, (2007) Mechanical stretching of proteins - a theoretical survey of the Protein Data Bank. J Phys Cond Mat 19: 283201.
-
(2007)
J Phys Cond Mat
, vol.19
, pp. 283201
-
-
Su lkowska, J.I.1
Cieplak, M.2
-
32
-
-
55949109149
-
Selection of optimal variants of Go-like models of proteins through studies of stretching
-
Su lkowska JI, Cieplak M, (2008) Selection of optimal variants of Go-like models of proteins through studies of stretching. Biophys J 95: 3174-3191.
-
(2008)
Biophys J
, vol.95
, pp. 3174-3191
-
-
Su lkowska, J.I.1
Cieplak, M.2
-
33
-
-
69549122277
-
On the remarkable mechanostability of scaffoldins and the mechanical clamp motif
-
Valbuena A, Oroz J, Hervas A, Vera AM, Rodriguez D, et al. (2009) On the remarkable mechanostability of scaffoldins and the mechanical clamp motif. Proc Natl Acad Sci USA 106: 13791-13796.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 13791-13796
-
-
Valbuena, A.1
Oroz, J.2
Hervas, A.3
Vera, A.M.4
Rodriguez, D.5
-
34
-
-
33747095897
-
Pulling Single Bacteriorhodopsin out of a Membrane: Comparison of simulation and experiment
-
Cieplak M, Filipek S, Janovjak H, Krzysko KA, (2006) Pulling Single Bacteriorhodopsin out of a Membrane: Comparison of simulation and experiment. BBA- Biomembranes 1758: 537-544.
-
(2006)
BBA - Biomembranes
, vol.1758
, pp. 537-544
-
-
Cieplak, M.1
Filipek, S.2
Janovjak, H.3
Krzysko, K.A.4
-
35
-
-
0007725036
-
Folding kinetics of proteinlike heteropolymers
-
Socci DN, Onuchic JN, (1994) Folding kinetics of proteinlike heteropolymers. J Chem Phys 101: 1519-1528.
-
(1994)
J Chem Phys
, vol.101
, pp. 1519-1528
-
-
Socci, D.N.1
Onuchic, J.N.2
-
36
-
-
0037069653
-
Structural basis of BMP signalling inhibition by the cystine knot protein Noggin
-
Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, et al. (2002) Structural basis of BMP signalling inhibition by the cystine knot protein Noggin. Nature 420: 636-42.
-
(2002)
Nature
, vol.420
, pp. 636-642
-
-
Groppe, J.1
Greenwald, J.2
Wiater, E.3
Rodriguez-Leon, J.4
Economides, A.N.5
-
37
-
-
0345255908
-
Nodal signaling in vertebrate development (2003) Annu Rev Cell Dev Biol
-
Schier AF, (2003) Nodal signaling in vertebrate development (2003) Annu Rev Cell Dev Biol. 19: 589-621.
-
(2003)
, vol.19
, pp. 589-621
-
-
Schier, A.F.1
-
38
-
-
0036240683
-
Inhibition of nodal signalling by lefty mediated through interaction with common receptors and efficient diffusion
-
Sakuma R, Ohnishi YI, Meno C, Fujii H, Juan H, et al. (2002) Inhibition of nodal signalling by lefty mediated through interaction with common receptors and efficient diffusion. Genes to Cells 7: 401-412.
-
(2002)
Genes to Cells
, vol.7
, pp. 401-412
-
-
Sakuma, R.1
Ohnishi, Y.I.2
Meno, C.3
Fujii, H.4
Juan, H.5
-
39
-
-
44449087047
-
Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy
-
Neuman KC, Nagy A, (2008) Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy. Nature Methods 5: 491-505.
-
(2008)
Nature Methods
, vol.5
, pp. 491-505
-
-
Neuman, K.C.1
Nagy, A.2
-
40
-
-
73549120339
-
Protein mechanics at the single-molecule level
-
Springer, Editor-in-chief R. A. Meyers, New York
-
Carrion-Vazquez M, Cieplak M, Oberhauser AF (2009) Protein mechanics at the single-molecule level. Encyclopedia of Complexity and Systems Science, Springer, Editor-in-chief R. A. Meyers, 7026-7050, New York.
-
(2009)
Encyclopedia of Complexity and Systems Science
, pp. 7026-7050
-
-
Carrion-Vazquez, M.1
Cieplak, M.2
Oberhauser, A.F.3
-
41
-
-
0042508741
-
Pulling geometry defines mechanical resistance of β-sheet protein
-
Brockwell DJ, Paci E, Zinober ERC, Beddard G, Olmsted PD, et al. (2003) Pulling geometry defines mechanical resistance of β-sheet protein. Nat Struct Biol 10: 731-737.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 731-737
-
-
Brockwell, D.J.1
Paci, E.2
Zinober, E.R.C.3
Beddard, G.4
Olmsted, P.D.5
-
42
-
-
27744539797
-
Mechanical unfolding of ubiquitin molecules
-
Cieplak M, Marszalek PE, (2005) Mechanical unfolding of ubiquitin molecules. J Chem Phys 123: 194903.
-
(2005)
J Chem Phys
, vol.123
, pp. 194903
-
-
Cieplak, M.1
Marszalek, P.E.2
-
44
-
-
84869065519
-
Cystine plug and other mechanisms of large mechanical stability in dimeric proteins
-
Sikora M, (2012) CieplakM (2012) Cystine plug and other mechanisms of large mechanical stability in dimeric proteins. Phys Rev Lett 109: 208101.
-
(2012)
Phys Rev Lett
, vol.109
, pp. 208101
-
-
Sikora, M.1
Cieplak, M.2
-
45
-
-
0037044844
-
Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif
-
Miles LA, Catherine DY, Nielsen J, Barnham KJ, Hiinds MG, et al. (2002) Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif. J Biol Chem 277: 43033-43040.
-
(2002)
J Biol Chem
, vol.277
, pp. 43033-43040
-
-
Miles, L.A.1
Catherine, D.Y.2
Nielsen, J.3
Barnham, K.J.4
Hiinds, M.G.5
-
46
-
-
78651290702
-
ModBase, a database of annotated comparative protein structure models, and associated resources
-
Pieper U, Webb BM, Barkan DT, Schneidman-Duhovny D, Schlessinger A, et al. (2011) ModBase, a database of annotated comparative protein structure models, and associated resources. Nucleic Acids Res 39: D465-74.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Pieper, U.1
Webb, B.M.2
Barkan, D.T.3
Schneidman-Duhovny, D.4
Schlessinger, A.5
-
47
-
-
0037044749
-
The Cystine Knot Promotes Folding and Not Thermodynamic Stability in Vascular Endothelial Growth Factor
-
Muller YA, Heiring C, Misselwitz R, Welfle K, Welfle H, (2002) The Cystine Knot Promotes Folding and Not Thermodynamic Stability in Vascular Endothelial Growth Factor. J Biol Chem 277: 43410-43416.
-
(2002)
J Biol Chem
, vol.277
, pp. 43410-43416
-
-
Muller, Y.A.1
Heiring, C.2
Misselwitz, R.3
Welfle, K.4
Welfle, H.5
-
48
-
-
80053443991
-
Recombinant expression, purification and dimerization of the neurotrophic growth factor Artemin for in vitro and in vivo use
-
Bruinzeel W, Masure S, (2012) Recombinant expression, purification and dimerization of the neurotrophic growth factor Artemin for in vitro and in vivo use. Prot Expr Purif 81: 25-32.
-
(2012)
Prot Expr Purif
, vol.81
, pp. 25-32
-
-
Bruinzeel, W.1
Masure, S.2
-
49
-
-
0028116165
-
The conformational stability of a non-covalent dimer of a platelet-derived growth factor-B mutant lacking the two cysteines involved in interchain disulfide bonds
-
Prestrelski SJ, Arakawa T, Ducker K, KenneyWC, Narhi LO, (2009) The conformational stability of a non-covalent dimer of a platelet-derived growth factor-B mutant lacking the two cysteines involved in interchain disulfide bonds Int. J. Peptide Protein Res. 44: 357.
-
(2009)
Int. J. Peptide Protein Res
, vol.44
, pp. 357
-
-
Prestrelski, S.J.1
Arakawa, T.2
Ducker, K.3
Kenney, W.C.4
Narhi, L.O.5
-
50
-
-
0027469152
-
Conformation of glutathione adduct and oxidized forms of platelet-derived growth factor
-
Narhi LO, Kenney WC, Prestrelski SJ, Arakawa T, Lyons D, et al. (1993) Conformation of glutathione adduct and oxidized forms of platelet-derived growth factor. Int J Pept Protein Res. 1993 41: 8-14.
-
(1993)
Int J Pept Protein Res
, vol.41
, pp. 8-14
-
-
Narhi, L.O.1
Kenney, W.C.2
Prestrelski, S.J.3
Arakawa, T.4
Lyons, D.5
-
51
-
-
0030037084
-
RhNGF slow unfolding is not due to proline isomerization: Possibility of a cystine knot loop-threading mechanism Protein Science
-
de Young LR, Burton LE, Liu J, Schmelzer CH, Skelton NJ, (1996) RhNGF slow unfolding is not due to proline isomerization: Possibility of a cystine knot loop-threading mechanism Protein Science. 5: 1554-1566.
-
(1996)
, vol.5
, pp. 1554-1566
-
-
de Young, L.R.1
Burton, L.E.2
Liu, J.3
Schmelzer, C.H.4
Skelton, N.J.5
-
52
-
-
0032718705
-
A common mechanism for recombinant human NGF, BDNF, NT-3, and murine NGF slow unfolding Protein Science
-
de Young LR, Schmelzer CH, Burton LE, (1999) A common mechanism for recombinant human NGF, BDNF, NT-3, and murine NGF slow unfolding Protein Science. 8: 2513-2518.
-
(1999)
, vol.8
, pp. 2513-2518
-
-
de Young, L.R.1
Schmelzer, C.H.2
Burton, L.E.3
|