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Volumn 7, Issue 2, 2013, Pages

Differential Expression of Toll-like Receptors in Dendritic Cells of Patients with Dengue during Early and Late Acute Phases of the Disease

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; B7 ANTIGEN; CD123 ANTIGEN; CD14 ANTIGEN; CD86 ANTIGEN; GLYCOPROTEIN P 15095; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9;

EID: 84874767745     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0002060     Document Type: Article
Times cited : (43)

References (52)
  • 2
    • 1542676405 scopus 로고    scopus 로고
    • Molecular biology of flaviviruses
    • Lindenbach BD, Rice CM, (2003) Molecular biology of flaviviruses. Adv Virus Res 59: 23-61.
    • (2003) Adv Virus Res , vol.59 , pp. 23-61
    • Lindenbach, B.D.1    Rice, C.M.2
  • 4
    • 0014775305 scopus 로고
    • Observations related to pathogenesis of dengue hemorrhagic fever IV. Relation of disease severity to antibody response and virus recovered
    • Halstead SB, Nimmannitya S, Cohen SN, (1970) Observations related to pathogenesis of dengue hemorrhagic fever IV. Relation of disease severity to antibody response and virus recovered. Yale J Biol MEd 42: 311-328.
    • (1970) Yale J Biol MEd , vol.42 , pp. 311-328
    • Halstead, S.B.1    Nimmannitya, S.2    Cohen, S.N.3
  • 6
    • 48749095596 scopus 로고    scopus 로고
    • Dengue in Vietnamese infants-results of infection-enhancement assays correlate with age-related disease epidemiology, and cellular immune responses correlate with disease severity
    • Chau TN, Quyen NT, Thuy TT, Tuan NM, Hoang DM, et al. (2008) Dengue in Vietnamese infants-results of infection-enhancement assays correlate with age-related disease epidemiology, and cellular immune responses correlate with disease severity. J Infect Dis 198: 516-524.
    • (2008) J Infect Dis , vol.198 , pp. 516-524
    • Chau, T.N.1    Quyen, N.T.2    Thuy, T.T.3    Tuan, N.M.4    Hoang, D.M.5
  • 7
    • 78951488927 scopus 로고    scopus 로고
    • Cell Type Specificity and Host Genetic Polymorphisms Influence Antibody-Dependent Enhancement of Dengue Virus Infection
    • Boonnak K, Dambach KM, Donofrio GC, Tassaneetrithep T, Marovich MA, (2011) Cell Type Specificity and Host Genetic Polymorphisms Influence Antibody-Dependent Enhancement of Dengue Virus Infection. J Virol 85: 1671-1683.
    • (2011) J Virol , vol.85 , pp. 1671-1683
    • Boonnak, K.1    Dambach, K.M.2    Donofrio, G.C.3    Tassaneetrithep, T.4    Marovich, M.A.5
  • 8
    • 68649109084 scopus 로고    scopus 로고
    • Role of antibodies in controlling dengue virus infection
    • van der Schaar HM, Wilschut JC, Smit JM, (2009) Role of antibodies in controlling dengue virus infection. Immunobiology 214: 613-629.
    • (2009) Immunobiology , vol.214 , pp. 613-629
    • van der Schaar, H.M.1    Wilschut, J.C.2    Smit, J.M.3
  • 9
    • 0033970916 scopus 로고    scopus 로고
    • Dengue Viremia Titer, Antibody Response Pattern, and Virus Serotype Correlate with Disease Severity
    • Vaughn DW, (2000) Dengue Viremia Titer, Antibody Response Pattern, and Virus Serotype Correlate with Disease Severity. J Infect Dis 181: 2-9.
    • (2000) J Infect Dis , vol.181 , pp. 2-9
    • Vaughn, D.W.1
  • 10
  • 11
    • 0037080024 scopus 로고    scopus 로고
    • Tissue Expression of Human Toll-Like Receptors and Differential Regulation of Toll-Like Receptor mRNAs in Leukocytes in Response to Microbes, Their Products, and Cytokines
    • Zarember KA, Godowski PJ, (2002) Tissue Expression of Human Toll-Like Receptors and Differential Regulation of Toll-Like Receptor mRNAs in Leukocytes in Response to Microbes, Their Products, and Cytokines. J Immunol 168: 554-561.
    • (2002) J Immunol , vol.168 , pp. 554-561
    • Zarember, K.A.1    Godowski, P.J.2
  • 12
    • 0035179882 scopus 로고    scopus 로고
    • Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells
    • Jarrossay D, Napolitani G, Colonna M, Sallusto F, Lanzavecchia A, (2001) Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells. Eur J Immunol 11: 3388-3393.
    • (2001) Eur J Immunol , vol.11 , pp. 3388-3393
    • Jarrossay, D.1    Napolitani, G.2    Colonna, M.3    Sallusto, F.4    Lanzavecchia, A.5
  • 13
    • 62149139785 scopus 로고    scopus 로고
    • Human TLR3 recognizes dengue virus and modulates viral replication in vitro
    • Tsai YT, Chang SY, Lee CN, Kao CL, (2009) Human TLR3 recognizes dengue virus and modulates viral replication in vitro. Cell Microbiol 11: 604-615.
    • (2009) Cell Microbiol , vol.11 , pp. 604-615
    • Tsai, Y.T.1    Chang, S.Y.2    Lee, C.N.3    Kao, C.L.4
  • 14
    • 78650710149 scopus 로고    scopus 로고
    • Subversion of innate defenses by the interplay between DENV and pre-existing enhancing antibodies: TLRs signaling collapse
    • Modhiran N, Kalayanarooj S, Ubol S, (2010) Subversion of innate defenses by the interplay between DENV and pre-existing enhancing antibodies: TLRs signaling collapse. PLoS Negl Trop Dis 4: e924.
    • (2010) PLoS Negl Trop Dis , vol.4
    • Modhiran, N.1    Kalayanarooj, S.2    Ubol, S.3
  • 15
    • 0036570169 scopus 로고    scopus 로고
    • Molecular and Structural Immunology: Quantitative Expression of Toll-Like Receptor 1-10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides
    • Hornung V, Rothenfusser S, Britsch S, Krug A, Jahrsdörfer B, et al. (2002) Molecular and Structural Immunology: Quantitative Expression of Toll-Like Receptor 1-10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides. J Immunol 168: 4531-4537.
    • (2002) J Immunol , vol.168 , pp. 4531-4537
    • Hornung, V.1    Rothenfusser, S.2    Britsch, S.3    Krug, A.4    Jahrsdörfer, B.5
  • 16
    • 77956397972 scopus 로고    scopus 로고
    • Acquisition of Adult-Like TLR4 and TLR9 Responses during the First Year of Life
    • Nguyen M, Leuridan E, Zhang T, De Wit D, Willems F, et al. (2010) Acquisition of Adult-Like TLR4 and TLR9 Responses during the First Year of Life. PLoS ONE 5: e10407.
    • (2010) PLoS ONE , vol.5
    • Nguyen, M.1    Leuridan, E.2    Zhang, T.3    De Wit, D.4    Willems, F.5
  • 17
    • 79957921699 scopus 로고    scopus 로고
    • Up-Regulation of TLR2 and TLR4 in Dendritic Cells in Response to HIV Type 1 and Coinfection with Opportunistic Pathogens
    • Hernandez JC, Arteaga J, Paul S, Kumar A, Latz E, et al. (2011) Up-Regulation of TLR2 and TLR4 in Dendritic Cells in Response to HIV Type 1 and Coinfection with Opportunistic Pathogens. AIDS Res Hum Retroviruses 10: 1099-1109.
    • (2011) AIDS Res Hum Retroviruses , vol.10 , pp. 1099-1109
    • Hernandez, J.C.1    Arteaga, J.2    Paul, S.3    Kumar, A.4    Latz, E.5
  • 18
    • 84861925077 scopus 로고    scopus 로고
    • HIV Type 1 Infection Up-Regulates TLR2 and TLR4 Expression and Function in Vivo and in Vitro
    • Hernandez JC, Stevenson M, Latz E, Urcuqui-Inchima S, (2012) HIV Type 1 Infection Up-Regulates TLR2 and TLR4 Expression and Function in Vivo and in Vitro. AIDS Res Hum Retroviruses 10: 1313-28.
    • (2012) AIDS Res Hum Retroviruses , vol.10 , pp. 1313-1328
    • Hernandez, J.C.1    Stevenson, M.2    Latz, E.3    Urcuqui-Inchima, S.4
  • 19
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, et al. (2000) A Toll-like receptor recognizes bacterial DNA. Nature 408: 740-745.
    • (2000) Nature , vol.408 , pp. 740-745
    • Hemmi, H.1    Takeuchi, O.2    Kawai, T.3    Kaisho, T.4    Sato, S.5
  • 20
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of Human Dendritic Cell Precursors Express Different Toll-like Receptors and Respond to Different Microbial Antigens
    • Kadowaki N, Ho S, Antonenko S, De Waal Malefyt R, Kastelein RA, et al. (2001) Subsets of Human Dendritic Cell Precursors Express Different Toll-like Receptors and Respond to Different Microbial Antigens. J Exp Med 194: 863-870.
    • (2001) J Exp Med , vol.194 , pp. 863-870
    • Kadowaki, N.1    Ho, S.2    Antonenko, S.3    de Waal Malefyt, R.4    Kastelein, R.A.5
  • 21
    • 77956928890 scopus 로고    scopus 로고
    • TLR3 and Rig-Like Receptor on Myeloid Dendritic Cells and Rig-Like Receptor on Human NK Cells Are Both Mandatory for Production of IFN-γ in Response to Double-Stranded RNA
    • Perrot I, Deauvieau F, Massacrier C, Hughes N, Garrone P, Durand I, et al. (2010) TLR3 and Rig-Like Receptor on Myeloid Dendritic Cells and Rig-Like Receptor on Human NK Cells Are Both Mandatory for Production of IFN-γ in Response to Double-Stranded RNA. J Immunol 185: 2080-2088.
    • (2010) J Immunol , vol.185 , pp. 2080-2088
    • Perrot, I.1    Deauvieau, F.2    Massacrier, C.3    Hughes, N.4    Garrone, P.5    Durand, I.6
  • 23
    • 0031045622 scopus 로고    scopus 로고
    • Origin, maturation and antigen presenting function of dendritic cells
    • Cella M, Sallusto F, Lanzavecchia A, (1997) Origin, maturation and antigen presenting function of dendritic cells. Curr Opin Immunol 9: 10-16.
    • (1997) Curr Opin Immunol , vol.9 , pp. 10-16
    • Cella, M.1    Sallusto, F.2    Lanzavecchia, A.3
  • 25
    • 0014462374 scopus 로고
    • Isolation of dengue viruses in Aedes albopictus cell cultures
    • Singh KR, Paul SD, (1969) Isolation of dengue viruses in Aedes albopictus cell cultures. Bull World Health Organ 40: 982-983.
    • (1969) Bull World Health Organ , vol.40 , pp. 982-983
    • Singh, K.R.1    Paul, S.D.2
  • 27
    • 33646168017 scopus 로고    scopus 로고
    • Improved Dengue Virus Plaque Formation on BHK21 and LLCMK2 Cells: Evaluation of Some factors
    • Alvarez M, Rodriguez-Roche R, Bernardo L, Morier L, Guzman MG, (2005) Improved Dengue Virus Plaque Formation on BHK21 and LLCMK2 Cells: Evaluation of Some factors. Dengue Bulletin 29: 49-57.
    • (2005) Dengue Bulletin , vol.29 , pp. 49-57
    • Alvarez, M.1    Rodriguez-Roche, R.2    Bernardo, L.3    Morier, L.4    Guzman, M.G.5
  • 28
    • 0036211288 scopus 로고    scopus 로고
    • Cytokine gene-expression and protein production in peripheral blood mononuclear cells of children with acute dengue virus infections
    • Gagnon SJ, Mori M, Kurane I, Green S, Vaughn DW, et al. (2002) Cytokine gene-expression and protein production in peripheral blood mononuclear cells of children with acute dengue virus infections. J Med Virol 67: 41-46.
    • (2002) J Med Virol , vol.67 , pp. 41-46
    • Gagnon, S.J.1    Mori, M.2    Kurane, I.3    Green, S.4    Vaughn, D.W.5
  • 29
    • 0028129410 scopus 로고
    • Production of interleukin-1 (IL-1) and IL-1 inhibitor by human monocytes exposed to dengue virus
    • Chang DM, Shaio MF, (1994) Production of interleukin-1 (IL-1) and IL-1 inhibitor by human monocytes exposed to dengue virus. J Infect Dis 170: 811-817.
    • (1994) J Infect Dis , vol.170 , pp. 811-817
    • Chang, D.M.1    Shaio, M.F.2
  • 30
    • 33751424404 scopus 로고    scopus 로고
    • MCP-1, a highly expressed chemokine in dengue haemorrhagic fever/dengue shock syndrome patients, may cause permeability change, possibly through reduced tight junctions of vascular endothelium cells
    • Lee YR, Liu MT, Lei HY, Liu CC, Wu JM, et al. (2006) MCP-1, a highly expressed chemokine in dengue haemorrhagic fever/dengue shock syndrome patients, may cause permeability change, possibly through reduced tight junctions of vascular endothelium cells. J Gen Virol 87: 3623-3630.
    • (2006) J Gen Virol , vol.87 , pp. 3623-3630
    • Lee, Y.R.1    Liu, M.T.2    Lei, H.Y.3    Liu, C.C.4    Wu, J.M.5
  • 31
    • 77952057526 scopus 로고    scopus 로고
    • Differential regulation of toll-like receptor-2, toll-like receptor-4, CD16 and human leucocyte antigen-DR on peripheral blood monocytes during mild and severe dengue fever
    • Azeredo EL, Neves-Souza PC, Alvarenga AR, Reis SR, Torrentes-Carvalho A, et al. (2010) Differential regulation of toll-like receptor-2, toll-like receptor-4, CD16 and human leucocyte antigen-DR on peripheral blood monocytes during mild and severe dengue fever. Immunology 130: 202-216.
    • (2010) Immunology , vol.130 , pp. 202-216
    • Azeredo, E.L.1    Neves-Souza, P.C.2    Alvarenga, A.R.3    Reis, S.R.4    Torrentes-Carvalho, A.5
  • 32
    • 79851492362 scopus 로고    scopus 로고
    • RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection
    • doi: 10.1371/journal.pntd.0000926
    • Nasirudeen AM, Wong HH, Thien P, Xu S, Lam KP, et al. (2011) RIG-I, MDA5 and TLR3 synergistically play an important role in restriction of dengue virus infection. PLoS Negl Trop Dis 5: e926 doi:10.1371/journal.pntd.0000926.
    • (2011) PLoS Negl Trop Dis , vol.5
    • Nasirudeen, A.M.1    Wong, H.H.2    Thien, P.3    Xu, S.4    Lam, K.P.5
  • 33
    • 33750813795 scopus 로고    scopus 로고
    • Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition
    • Wang JP, Liu P, Latz E, Golenbock DT, Finberg RW, et al. (2006) Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition. J Immunol 177: 7114-7121.
    • (2006) J Immunol , vol.177 , pp. 7114-7121
    • Wang, J.P.1    Liu, P.2    Latz, E.3    Golenbock, D.T.4    Finberg, R.W.5
  • 34
    • 0035078793 scopus 로고    scopus 로고
    • Human dendritic cells are activated by dengue virus infection: enhancement by gamma interferon and implications for disease pathogenesis
    • Libraty DH, Pichyangkul S, Ajariyakhajorn C, Endy TP, Ennis FA, (2001) Human dendritic cells are activated by dengue virus infection: enhancement by gamma interferon and implications for disease pathogenesis. J Virol 75: 3501-3508.
    • (2001) J Virol , vol.75 , pp. 3501-3508
    • Libraty, D.H.1    Pichyangkul, S.2    Ajariyakhajorn, C.3    Endy, T.P.4    Ennis, F.A.5
  • 35
    • 13444304281 scopus 로고    scopus 로고
    • Differential effects of dengue virus on infected and bystander dendritic cells
    • Palmer DR, Sun P, Celluzzi C, Bisbing J, Pang S, et al. (2005) Differential effects of dengue virus on infected and bystander dendritic cells. J Virol 79: 2432-2439.
    • (2005) J Virol , vol.79 , pp. 2432-2439
    • Palmer, D.R.1    Sun, P.2    Celluzzi, C.3    Bisbing, J.4    Pang, S.5
  • 36
    • 39149126659 scopus 로고    scopus 로고
    • Effect of intrauterine HIV-1 exposure on the frequency and function of uninfected newborns' dendritic cells
    • Velilla PA, Montoya CJ, Hoyos A, Moreno ME, Chougnet C, Rugeles MT, (2008) Effect of intrauterine HIV-1 exposure on the frequency and function of uninfected newborns' dendritic cells. Clin Immunol 3: 243-50.
    • (2008) Clin Immunol , vol.3 , pp. 243-250
    • Velilla, P.A.1    Montoya, C.J.2    Hoyos, A.3    Moreno, M.E.4    Chougnet, C.5    Rugeles, M.T.6
  • 37
    • 77956859036 scopus 로고    scopus 로고
    • Inhibition of the Type I Interferon Response in Human Dendritic Cells by Dengue Virus Infection Requires a Catalytically Active NS2B3 Complex
    • Rodriguez-Madoz JR, Belicha-Villanueva A, Bernal-Rubio D, Ashou J, Ayllon J, et al. (2010) Inhibition of the Type I Interferon Response in Human Dendritic Cells by Dengue Virus Infection Requires a Catalytically Active NS2B3 Complex. J Virol 84: 9760-74.
    • (2010) J Virol , vol.84 , pp. 9760-9774
    • Rodriguez-Madoz, J.R.1    Belicha-Villanueva, A.2    Bernal-Rubio, D.3    Ashou, J.4    Ayllon, J.5
  • 39
    • 70349432365 scopus 로고    scopus 로고
    • Dengue virus NS5 inhibits interferon-alpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation
    • Mazzon M, Jones M, Davidson A, Chain B, Jacobs M, (2009) Dengue virus NS5 inhibits interferon-alpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation. J Infect Dis 200: 1261-70.
    • (2009) J Infect Dis , vol.200 , pp. 1261-1270
    • Mazzon, M.1    Jones, M.2    Davidson, A.3    Chain, B.4    Jacobs, M.5
  • 40
    • 33846079822 scopus 로고    scopus 로고
    • Of cascades and perfect storms: the immunopathogenesis of dengue haemorrhagic fever-dengue shock syndrome (DHF/DSS)
    • Pang T, Cardosa MJ, Guzman MG, (2007) Of cascades and perfect storms: the immunopathogenesis of dengue haemorrhagic fever-dengue shock syndrome (DHF/DSS). Immunol Cell Biol 85: 43-45.
    • (2007) Immunol Cell Biol , vol.85 , pp. 43-45
    • Pang, T.1    Cardosa, M.J.2    Guzman, M.G.3
  • 41
    • 0015949926 scopus 로고
    • Identification of a novel cell type in peripheral lymphoid organs of mice II. Functional properties in vitro
    • Steinman RM, Cohn ZA, (1974) Identification of a novel cell type in peripheral lymphoid organs of mice II. Functional properties in vitro. J Exp Med 139: 380-397.
    • (1974) J Exp Med , vol.139 , pp. 380-397
    • Steinman, R.M.1    Cohn, Z.A.2
  • 43
    • 58149116611 scopus 로고    scopus 로고
    • Functional characterization of ex vivo blood myeloid and plasmacytoid dendritic cells after infection with dengue virus
    • Sun P, Fernandez S, Marovich MA, Palmer DR, Celluzzi CM, et al. (2009) Functional characterization of ex vivo blood myeloid and plasmacytoid dendritic cells after infection with dengue virus. Virology 383: 207-215.
    • (2009) Virology , vol.383 , pp. 207-215
    • Sun, P.1    Fernandez, S.2    Marovich, M.A.3    Palmer, D.R.4    Celluzzi, C.M.5
  • 44
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3
    • Alexopoulou L, Holt AC, Medzhitov R, Flavell RA, (2001) Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413: 732-738.
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 45
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg AM, (2002) CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 20: 709-760.
    • (2002) Annu Rev Immunol , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 46
    • 34548423284 scopus 로고    scopus 로고
    • Negative regulation of TLR9-mediated IFN-α induction by a small-molecule, synthetic TLR7 ligand
    • Marshall JD, Heeke DS, Gesner ML, Livingston B, Van Nest G, (2007) Negative regulation of TLR9-mediated IFN-α induction by a small-molecule, synthetic TLR7 ligand. J Leukocyte Biol 82: 1-12.
    • (2007) J Leukocyte Biol , vol.82 , pp. 1-12
    • Marshall, J.D.1    Heeke, D.S.2    Gesner, M.L.3    Livingston, B.4    Van Nest, G.5
  • 47
    • 28844460239 scopus 로고    scopus 로고
    • The Tumor Supressor Cylindromatosis (CYLD) Acts as a Negative Regulator for Toll-like Receptor 2 Signaling via Negative Cross-talk with TRAF6 and TRAF7
    • Yoshida H, Jono H, Kai H, Li JD, (2005) The Tumor Supressor Cylindromatosis (CYLD) Acts as a Negative Regulator for Toll-like Receptor 2 Signaling via Negative Cross-talk with TRAF6 and TRAF7. J Biol Chem 280: 41111-41121.
    • (2005) J Biol Chem , vol.280 , pp. 41111-41121
    • Yoshida, H.1    Jono, H.2    Kai, H.3    Li, J.D.4
  • 48
    • 80355133197 scopus 로고    scopus 로고
    • Infection and activation of human peripheral blood monocytes by dengue viruses through the mechanism of antibody-dependent enhancement
    • Sun P, Bauza K, Pal S, Liang Z, Wu SJ, (2011) Infection and activation of human peripheral blood monocytes by dengue viruses through the mechanism of antibody-dependent enhancement. Virol 421: 245-252.
    • (2011) Virol , vol.421 , pp. 245-252
    • Sun, P.1    Bauza, K.2    Pal, S.3    Liang, Z.4    Wu, S.J.5
  • 49
    • 36048975791 scopus 로고    scopus 로고
    • Hepatitis C virus infection induces the beta interferon signaling pathway in immortalized human hepatocytes
    • Kanda T, Steele R, Ray R, Ray RB, (2007) Hepatitis C virus infection induces the beta interferon signaling pathway in immortalized human hepatocytes. J Virol 81: 12375-12381.
    • (2007) J Virol , vol.81 , pp. 12375-12381
    • Kanda, T.1    Steele, R.2    Ray, R.3    Ray, R.B.4
  • 51
    • 23444438390 scopus 로고    scopus 로고
    • Altered cytokine responses of dengue specific CD4+ T cells to heterologous serotypes
    • Mangada MM, Rothman AL, (2005) Altered cytokine responses of dengue specific CD4+ T cells to heterologous serotypes. J immunol 175: 2676-2683.
    • (2005) J Immunol , vol.175 , pp. 2676-2683
    • Mangada, M.M.1    Rothman, A.L.2
  • 52
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: critical proteins linking innate and acquired immunity
    • Akira S, (2001) Toll-like receptors: critical proteins linking innate and acquired immunity. Nature 2: 675-680.
    • (2001) Nature , vol.2 , pp. 675-680
    • Akira, S.1


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