Negative regulation of TLR9-mediated IFN-α induction by a small-molecule, synthetic TLR7 ligand

Journal of Leukocyte Biology

Volumn 82, Issue 3, 2007, Pages 497-508

  Marshall, Jason D ^a   Heeke, Darren S ^a   Gesner, Marianne L ^a   Livingston, Brian ^a   Van Nest, Gary ^a  

^a Dynavax Technologies Corporation   (United States)

Author keywords

PDCs; TLR7; TLR9; Type I interferon

Indexed keywords

ALPHA INTERFERON; ANTIGEN; B7 ANTIGEN; BDCA 2; CD86 ANTIGEN; IMIQUIMOD; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 6; LIGAND; MESSENGER RNA; RESIQUIMOD; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

ARTICLE; B LYMPHOCYTE; CELL KINETICS; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; CPG ISLAND; DENDRITIC CELL; DOWN REGULATION; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIGENS, CD80; ANTIGENS, CD86; B-LYMPHOCYTES; CELL DIFFERENTIATION; CELL PROLIFERATION; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; INTERFERON-ALPHA; LECTINS, C-TYPE; LIGANDS; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; OLIGODEOXYRIBONUCLEOTIDES; RECEPTORS, IMMUNOLOGIC; RNA, MESSENGER; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 9;

EID: 34548423284     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0906575     Document Type: Article

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