Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression

Respiratory Research

Volumn 14, Issue 1, 2013, Pages

  Todt, Jill C ^a   Freeman, Christine M ^a,b   Brown, Jeanette P ^a   Sonstein, Joanne ^a   Ames, Theresa M ^a   McCubbrey, Alexandra L ^a   Martinez, Fernando J ^a   Chensue, Stephen W ^a,b   Beck, James M ^a,b   Curtis, Jeffrey L ^a,b  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

Author keywords

Alveolar; Cigarette smoking; Effects; Lung; Macrophages; Toll like receptors

Indexed keywords

CIGARETTE SMOKE; COLECALCIFEROL; DOUBLE STRANDED RNA; GAMMA INTERFERON INDUCIBLE PROTEIN 10; MESSENGER RNA; MU OPIATE RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; VIRUS NUCLEOPROTEIN; TLR3 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; CELL DIFFERENTIATION; CELL LINE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FLOW CYTOMETRY; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; LUNG RESECTION; MALE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SMOKING; BIOSYNTHESIS; CELL CULTURE; CLINICAL TRIAL; COHORT ANALYSIS; CYTOLOGY; DOWN REGULATION; DRUG ANTAGONISM; GENETICS; LUNG; METABOLISM; MIDDLE AGED; VIROLOGY; YOUNG ADULT; ANTAGONISTS AND INHIBITORS;

ADULT; AGED; CELL LINE; CELLS, CULTURED; COHORT STUDIES; DOWN-REGULATION; FEMALE; HUMANS; LUNG; MACROPHAGES, ALVEOLAR; MALE; MIDDLE AGED; RNA, DOUBLE-STRANDED; SMOKING; TOLL-LIKE RECEPTOR 3; YOUNG ADULT;

EID: 84874694046     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-14-33     Document Type: Article

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