An investigation into the effect of spray drying temperature and atomizing conditions on miscibility, physical stability, and performance of naproxen-PVP K 25 solid dispersions

Journal of Pharmaceutical Sciences

Volumn 102, Issue 4, 2013, Pages 1249-1267

  Paudel, Amrit ^a   Loyson, Yves ^a   Van den Mooter, Guy ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Amorphous; Compositional heterogeneity; Crystallization; Infrared spectroscopy; Physical stability; Solid dispersion; Spray drying

Indexed keywords

NAPROXEN; POVIDONE;

AIRFLOW; ARTICLE; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG SOLUBILITY; DRUG STABILITY; GLASS TRANSITION TEMPERATURE; HUMIDITY; HYDROGEN BOND; INFRARED SPECTROMETRY; MISCIBILITY; MOISTURE; SPRAY DRYING; TABLET COMPRESSION; TEMPERATURE SENSITIVITY; X RAY DIFFRACTION;

EID: 84874675191     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23459     Document Type: Article

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