Brain regional differences in CB1 receptor adaptation and regulation of transcription

Life Sciences

Volumn 92, Issue 8-9, 2013, Pages 446-452

  Lazenka, M F ^a   Selley, D E ^a   Sim Selley, L J ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

9 THC; FosB; Cannabinoid receptor; CREB; G protein; Immediate early genes

Indexed keywords

CANNABINOID 1 RECEPTOR; CYCLIC AMP; PROTEIN C FOS; TETRAHYDROCANNABINOL; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FOSB; TRANSCRIPTION FACTOR FRA 1; TRANSCRIPTION FACTOR FRA 2;

BRAIN REGION; CONFERENCE PAPER; CORPUS STRIATUM; DESENSITIZATION; DOWN REGULATION; FOREBRAIN; HIPPOCAMPUS; HUMAN; IMMEDIATE EARLY GENE; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PROTEIN PHOSPHORYLATION;

BRAIN CHEMISTRY; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DOWN-REGULATION; GENE EXPRESSION; GENES, FOS; GENES, IMMEDIATE-EARLY; HUMANS; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTOR, CANNABINOID, CB1; TETRAHYDROCANNABINOL;

CANNABIS SATIVA;

EID: 84874657739     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2012.08.023     Document Type: Conference Paper

References (67)

1. American Psychiatric Association Diagnostic and statistical manual of mental disorders: DSM-IV-TR 4th ed. 2000 Washington, DC
2. C.E. Bass, S.P. Welch, and B.R. Martin Reversal of delta 9-tetrahydrocannabinol-induced tolerance by specific kinase inhibitors Eur J Pharmacol 496 2004 99 108 (Pubitemid 39024322)
3. J.A. Bibb, G.L. Snyder, A. Nishi, Z. Yan, L. Meijer, and A.A. Fienberg Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons Nature 402 1999 669 671 (Pubitemid 129516337)
4. C. Blazquez, A. Chiarlone, O. Sagredo, T. Aguado, M.R. Pazos, and E. Resel Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease Brain 134 2011 119 136
5. A. Borgkvist, and G. Fisone Psychoactive drugs and regulation of the cAMP/PKA/DARPP-32 cascade in striatal medium spiny neurons Neurosci Biobehav Rev 31 2007 79 88 (Pubitemid 44880073)
6. A.A. Boucher, L. Vivier, M. Metna-Laurent, L. Brayda-Bruno, N. Mons, and J.C. Arnold Chronic treatment with Delta(9)-tetrahydrocannabinol impairs spatial memory and reduces zif268 expression in the mouse forebrain Behav Pharmacol 20 2009 45 55
7. C.S. Breivogel, S.R. Childers, S.A. Deadwyler, R.E. Hampson, L.J. Vogt, and L.J. Sim-Selley Chronic delta9-tetrahydrocannabinol treatment produces a time-dependent loss of cannabinoid receptors and cannabinoid receptor-activated G proteins in rat brain J Neurochem 73 1999 2447 2459
8. C. Capper-Loup, J.J. Canales, N. Kadaba, and A.M. Graybiel Concurrent activation of dopamine D1 and D2 receptors is required to evoke neural and behavioral phenotypes of cocaine sensitization J Neurosci 22 2002 6218 6227 (Pubitemid 35387662)
9. M.A. Carai, G. Colombo, and G.L. Gessa Rimonabant: the first therapeutically relevant cannabinoid antagonist Life Sci 77 2005 2339 2350 (Pubitemid 41206861)
10. M.A. Casu, C. Pisu, A. Sanna, S. Tambaro, G.P. Spada, and R. Mongeau Effect of delta9-tetrahydrocannabinol on phosphorylated CREB in rat cerebellum: an immunohistochemical study Brain Res 1048 2005 41 47 (Pubitemid 40800258)
11. J. Chen, M.B. Kelz, B.T. Hope, Y. Nakabeppu, and E.J. Nestler Chronic Fos-related antigens: stable variants of deltaFosB induced in brain by chronic treatments J Neurosci 17 1997 4933 4941 (Pubitemid 27263807)
12. J. Chen, M.B. Kelz, G. Zeng, N. Sakai, C. Steffen, and P.E. Shockett Transgenic animals with inducible, targeted gene expression in brain Mol Pharmacol 54 1998 495 503 (Pubitemid 28442942)
13. D.C. D'Souza, M. Ranganathan, G. Braley, R. Gueorguieva, Z. Zimolo, and T. Cooper Blunted psychotomimetic and amnestic effects of delta-9- tetrahydrocannabinol in frequent users of cannabis Neuropsychopharmacology 33 2008 2505 2516
14. V. De Chiara, F. Angelucci, S. Rossi, A. Musella, F. Cavasinni, and C. Cantarella Brain-derived neurotrophic factor controls cannabinoid CB1 receptor function in the striatum J Neurosci 30 2010 8127 8137
15. P. Derkinderen, E. Valjent, M. Toutant, J.C. Corvol, H. Enslen, and C. Ledent Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus J Neurosci 23 2003 2371 2382 (Pubitemid 36368926)
16. M. Erdtmann-Vourliotis, P. Mayer, U. Riechert, and V. Hollt Acute injection of drugs with low addictive potential (delta(9)-tetrahydrocannabinol, 3,4-methylenedioxymethamphetamine, lysergic acid diamide) causes a much higher c-fos expression in limbic brain areas than highly addicting drugs (cocaine and morphine) Brain Res Mol Brain Res 71 1999 313 324 (Pubitemid 29492975)
17. N. Fan, H. Yang, J. Zhang, and C. Chen Reduced expression of glutamate receptors and phosphorylation of CREB are responsible for in vivo Delta9-THC exposure-impaired hippocampal synaptic plasticity J Neurochem 112 2010 691 702
18. N.S. Foulkes, and P. Sassone-Corsi More is better: activators and repressors from the same gene Cell 68 1992 411 414
19. S. Ghozland, H.W. Matthes, F. Simonin, D. Filliol, B.L. Kieffer, and R. Maldonado Motivational effects of cannabinoids are mediated by mu-opioid and kappa-opioid receptors J Neurosci 22 2002 1146 1154 (Pubitemid 34141794)
20. M. Glass, and M. Dragunow Induction of the Krox 24 transcription factor in striosomes by a cannabinoid agonist Neuroreport 6 1995 241 244
21. M. Haney, C.L. Hart, S.K. Vosburg, J. Nasser, A. Bennett, and C. Zubaran Marijuana withdrawal in humans: effects of oral THC or divalproex Neuropsychopharmacology 29 2004 158 170 (Pubitemid 38068026)
22. T. Herdegen, and J.D. Leah Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins Brain Res Brain Res Rev 28 1998 370 490 (Pubitemid 29012678)
23. J. Hirvonen, R.S. Goodwin, C.T. Li, G.E. Terry, S.S. Zoghbi, and C. Morse Reversible and regionally selective downregulation of brain cannabinoid CB(1) receptors in chronic daily cannabis smokers Mol Psychiatry 17 2012 642 649
24. A.G. Hohmann, and M. Herkenham Localization of cannabinoid CB(1) receptor mRNA in neuronal subpopulations of rat striatum: a double-label in situ hybridization study Synapse 37 2000 71 80 (Pubitemid 30366503)
25. A.C. Howlett, F. Barth, T.I. Bonner, G. Cabral, P. Casellas, and W.A. Devane International Union of Pharmacology. XXVII. Classification of cannabinoid receptors Pharmacol Rev 54 2002 161 202 (Pubitemid 34575709)
26. A.B. James, A.M. Conway, and B.J. Morris Regulation of the neuronal proteasome by Zif268 (Egr1) J Neurosci 26 2006 1624 1634 (Pubitemid 43237033)
27. T. Kasukawa, K.H. Masumoto, I. Nikaido, M. Nagano, K.D. Uno, and K. Tsujino Quantitative expression profile of distinct functional regions in the adult mouse brain PLoS One 6 2011 e23228
28. M.F. Lazenka, H. He, D.E. Selley, and L.J. Sim-Selley Brain region-dependent correlation between ΔFosB induction and the desensitization and downregulation of CB1 receptors following repeated THC administration Carolina Cannabinoid Collaborative 2011
29. M.C. Lee, F.L. Smith, D.L. Stevens, and S.P. Welch The role of several kinases in mice tolerant to delta 9-tetrahydrocannabinol J Pharmacol Exp Ther 305 2003 593 599 (Pubitemid 36459175)
30. P. Mailleux, M. Verslype, X. Preud'homme, and J.J. Vanderhaeghen Activation of multiple transcription factor genes by tetrahydrocannabinol in rat forebrain Neuroreport 5 1994 1265 1268 (Pubitemid 24199813)
31. R. Maldonado, O. Valverde, and F. Berrendero Involvement of the endocannabinoid system in drug addiction Trends Neurosci 29 2006 225 232
32. C. Marie-Claire, I. Laurendeau, C. Canestrelli, C. Courtin, M. Vidaud, and B. Roques Fos but not Cart (cocaine and amphetamine regulated transcript) is overexpressed by several drugs of abuse: a comparative study using real-time quantitative polymerase chain reaction in rat brain Neurosci Lett 345 2003 77 80 (Pubitemid 36734866)
33. B.R. Martin, L.J. Sim-Selley, and D.E. Selley Signaling pathways involved in the development of cannabinoid tolerance Trends Pharmacol Sci 25 2004 325 330 (Pubitemid 38692425)
34. C.A. McClung, and E.J. Nestler Regulation of gene expression and cocaine reward by CREB and DeltaFosB Nat Neurosci 6 2003 1208 1215 (Pubitemid 37346042)
35. V. Mendizabal, A. Zimmer, and R. Maldonado Involvement of kappa/dynorphin system in WIN 55,212-2 self-administration in mice Neuropsychopharmacology 31 2006 1957 1966
36. A. Miyamoto, T. Yamamoto, M. Ohno, and S. Watanabe Desensitization of Fos protein induction in rat striatum and nucleus accumbens following repeated administration of delta9-tetrahydrocannabinol Brain Res 763 1997 137 140 (Pubitemid 27323749)
37. A. Miyamoto, T. Yamamoto, M. Ohno, S. Watanabe, H. Tanaka, and S. Morimoto Roles of dopamine D1 receptors in delta 9-tetrahydrocannabinol-induced expression of Fos protein in the rat brain Brain Res 710 1996 234 240
38. R. Moratalla, H.A. Robertson, and A.M. Graybiel Dynamic regulation of NGFI-A (zif268, egr1) gene expression in the striatum J Neurosci 12 1992 2609 2622
39. E.J. Nestler Molecular mechanisms of drug addiction Neuropharmacology 47 Suppl. 1 2004 24 32 (Pubitemid 39298250)
40. E.J. Nestler Review. Transcriptional mechanisms of addiction: role of DeltaFosB Philos Trans R Soc Lond B Biol Sci 363 2008 3245 3255
41. M.C. Peakman, C. Colby, L.I. Perrotti, P. Tekumalla, T. Carle, and P. Ulery Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine Brain Res 970 2003 73 86 (Pubitemid 36423183)
42. L.I. Perrotti, C.A. Bolanos, K.H. Choi, S.J. Russo, S. Edwards, and P.G. Ulery DeltaFosB accumulates in a GABAergic cell population in the posterior tail of the ventral tegmental area after psychostimulant treatment Eur J Neurosci 21 2005 2817 2824 (Pubitemid 40835124)
43. L.I. Perrotti, R.R. Weaver, B. Robison, W. Renthal, I. Maze, and S. Yazdani Distinct patterns of DeltaFosB induction in brain by drugs of abuse Synapse 62 2008 358 369 (Pubitemid 351451804)
44. A. Porcella, G.L. Gessa, and L. Pani Delta9-tetrahydrocannabinol increases sequence-specific AP-1 DNA-binding activity and Fos-related antigens in the rat brain Eur J Neurosci 10 1998 1743 1751
45. W. Renthal, T.L. Carle, I. Maze, H.E. Covington 3rd, H.T. Truong, and I. Alibhai Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure J Neurosci 28 2008 7344 7349
46. D. Robbe, G. Alonso, F. Duchamp, J. Bockaert, and O.J. Manzoni Localization and mechanisms of action of cannabinoid receptors at the glutamatergic synapses of the mouse nucleus accumbens J Neurosci 21 2001 109 116 (Pubitemid 32098732)
47. A.J. Robison, and E.J. Nestler Transcriptional and epigenetic mechanisms of addiction Nat Rev Neurosci 12 2011 623 637
48. T. Rubino, G. Forlani, D. Vigano, R. Zippel, and D. Parolaro Modulation of extracellular signal-regulated kinases cascade by chronic delta 9-tetrahydrocannabinol treatment Mol Cell Neurosci 25 2004 355 362 (Pubitemid 38366401)
49. T. Rubino, G. Forlani, D. Vigano, R. Zippel, and D. Parolaro Ras/ERK signalling in cannabinoid tolerance: from behaviour to cellular aspects J Neurochem 93 2005 984 991 (Pubitemid 40695757)
50. T. Rubino, C. Guidali, D. Vigano, N. Realini, M. Valenti, and P. Massi CB1 receptor stimulation in specific brain areas differently modulate anxiety-related behaviour Neuropharmacology 54 2008 151 160 (Pubitemid 350299412)
51. T. Rubino, D. Vigano, P. Massi, and D. Parolaro Cellular mechanisms of Delta 9-tetrahydrocannabinol behavioural sensitization Eur J Neurosci 17 2003 325 330 (Pubitemid 36459512)
52. T. Rubino, D. Vigano, F. Premoli, C. Castiglioni, S. Bianchessi, and R. Zippel Changes in the expression of G protein-coupled receptor kinases and beta-arrestins in mouse brain during cannabinoid tolerance: a role for RAS-ERK cascade Mol Neurobiol 33 2006 199 213 (Pubitemid 44284208)
53. M. Sheng, M.A. Thompson, and M.E. Greenberg CREB: a Ca(2 +)-regulated transcription factor phosphorylated by calmodulin-dependent kinases Science 252 1991 1427 1430 (Pubitemid 21917061)
54. L.J. Sim-Selley Regulation of cannabinoid CB1 receptors in the central nervous system by chronic cannabinoids Crit Rev Neurobiol 15 2003 91 119 (Pubitemid 38160440)
55. L.J. Sim-Selley, M.P. Cassidy, A. Sparta, V. Zachariou, E.J. Nestler, and D.E. Selley Effect of DeltaFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens Neuropharmacology 61 2011 1470 1476
56. L.J. Sim-Selley, N.S. Schechter, W.K. Rorrer, G.D. Dalton, J. Hernandez, and B.R. Martin Prolonged recovery rate of CB1 receptor adaptation after cessation of long-term cannabinoid administration Mol Pharmacol 70 2006 986 996 (Pubitemid 44268455)
57. E.T. Tzavara, K. Monory, S. Garel, P. Topilko, P. Charnay, and J. Hanoune Effects of cannabinoids in Krox-24 targeted mice Neuroreport 12 2001 1367 1370 (Pubitemid 32476131)
58. P.G. Ulery, G. Rudenko, and E.J. Nestler Regulation of DeltaFosB stability by phosphorylation J Neurosci 26 2006 5131 5142
59. E. Valjent, V. Pascoli, P. Svenningsson, S. Paul, H. Enslen, and J.C. Corvol Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum Proc Natl Acad Sci U S A 102 2005 491 496 (Pubitemid 40116794)
60. O. Valverde, M. Karsak, and A. Zimmer Analysis of the endocannabinoid system by using CB1 cannabinoid receptor knockout mice Handb Exp Pharmacol 2005 117 145
61. D. Vigano, T. Rubino, A. Vaccani, S. Bianchessi, P. Marmorato, and C. Castiglioni Molecular mechanisms involved in the asymmetric interaction between cannabinoid and opioid systems Psychopharmacology 182 2005 527 536 (Pubitemid 41464634)
62. J. Villares Chronic use of marijuana decreases cannabinoid receptor binding and mRNA expression in the human brain Neuroscience 145 2007 323 334 (Pubitemid 46237689)
63. N.M. White, and N. Hiroi Preferential localization of self-stimulation sites in striosomes/patches in the rat striatum Proc Natl Acad Sci U S A 95 1998 6486 6491 (Pubitemid 28249040)
64. J. Wiskerke, T. Pattij, A.N. Schoffelmeer, and T.J. De Vries The role of CB1 receptors in psychostimulant addiction Addict Biol 13 2008 225 238 (Pubitemid 351692984)
65. K. Yoshioka, T. Deng, M. Cavigelli, and M. Karin Antitumor promotion by phenolic antioxidants: inhibition of AP-1 activity through induction of Fra expression Proc Natl Acad Sci U S A 92 1995 4972 4976
66. V. Zachariou, C.A. Bolanos, D.E. Selley, D. Theobald, M.P. Cassidy, and M.B. Kelz An essential role for DeltaFosB in the nucleus accumbens in morphine action Nat Neurosci 9 2006 205 211 (Pubitemid 43164543)
67. A. Zimmer, E. Valjent, M. Konig, A.M. Zimmer, P. Robledo, and H. Hahn Absence of delta - 9-tetrahydrocannabinol dysphoric effects in dynorphin-deficient mice J Neurosci 21 2001 9499 9505 (Pubitemid 33096894)