ΔFosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure

Journal of Neuroscience

Volumn 28, Issue 29, 2008, Pages 7344-7349

  Renthal, William ^a   Carle, Tiffany L ^a   Maze, Ian ^a   Covington III, Herbert E ^a   Truong, Hoang Trang ^a   Alibhai, Imran ^a   Kumar, Arvind ^a   Montgomery, Rusty L ^b   Olson, Eric N ^b   Nestler, Eric J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Addiction; Amphetamine; Chromatin; Gene regulation; Histone modification; Striatum

Indexed keywords

AMPHETAMINE; HISTONE DEACETYLASE 1; MESSENGER RNA; TRANSCRIPTION FACTOR FOSB; FOSB PROTEIN, MOUSE; FOSB PROTEIN, RAT; HDAC1 PROTEIN, RAT; HISTONE DEACETYLASE; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; CORPUS STRIATUM; DRUG DEPENDENCE; EPIGENETICS; GENE ACTIVITY; GENE EXPRESSION; GENE EXPRESSION REGULATION; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROMOTER REGION; RAT; ANIMAL; ANIMAL BEHAVIOR; BIOSYNTHESIS; CELL STRAIN; COMPARATIVE STUDY; DOWN REGULATION; DRUG ADMINISTRATION; DRUG ANTAGONISM; DRUG EFFECT; GENETIC EPIGENESIS; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY; PROTEIN TRANSPORT; TRANSGENIC MOUSE; UPREGULATION;

AMPHETAMINE; ANIMALS; BEHAVIOR, ANIMAL; DOWN-REGULATION; DRUG ADMINISTRATION SCHEDULE; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HISTONE DEACETYLASES; MICE; MICE, TRANSGENIC; PC12 CELLS; PROMOTER REGIONS (GENETICS); PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RNA, MESSENGER; UP-REGULATION;

EID: 49049122082     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1043-08.2008     Document Type: Article

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