Induction of the cystine/glutamate exchanger SLC7A11 in retinal pigment epithelial cells by the antipsoriatic drug monomethylfumarate

Investigative Ophthalmology and Visual Science

Volumn 54, Issue 3, 2013, Pages 1592-1602

  Ananth, Sudha ^a   Babu, Ellappan ^a   Veeranan Karmegam, Rajalakshmi ^a   Baldowski, Brooke R Bozard ^a   Boettger, Thomas ^b   Martin, Pamela M ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSPORTER; CYSTINE; FUMARIC ACID ETHYL ESTER; GLUTAMIC ACID; GLUTATHIONE; HEME OXYGENASE 1; HYPOXIA INDUCIBLE FACTOR 1; IBUPROFEN; MONOCARBOXYLATE TRANSPORTER; PYRUVIC ACID; SLC 7A11; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; KINETICS; MALE; MOUSE; NONHUMAN; OOCYTE; OXIDATIVE STRESS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STIMULATION; UPREGULATION; WESTERN BLOTTING; XENOPUS LAEVIS;

AMINO ACID TRANSPORT SYSTEM Y+; ANIMALS; CELLS, CULTURED; DERMATOLOGIC AGENTS; EPITHELIAL CELLS; EYE; FUMARATES; GLUTATHIONE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALEATES; MICE; MICE, INBRED BALB C; NF-E2-RELATED FACTOR 2; RETINAL PIGMENT EPITHELIUM; RNA, MESSENGER; UP-REGULATION;

EID: 84874634227     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-11289     Document Type: Article

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