Interaction of ibuprofen and other structurally related NSAIDs with the sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8)

Pharmaceutical Research

Volumn 23, Issue 6, 2006, Pages 1209-1216

  Itagaki, Shirou ^a   Gopal, Elangovan ^a   Zhuang, Lina ^a   Fei, You Jun ^a   Miyauchi, Seiji ^a   Prasad, Puttur D ^a   Ganapathy, Vadivel ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Blocker; Electrophysiology; Ibuprofen; SMCT1; Sodium dependence

Indexed keywords

CARBON 14; FENOPROFEN; IBUPROFEN; KETOPROFEN; MONOCARBOXYLATE TRANSPORTER; NAPROXEN; NICOTINIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; PROPIONIC ACID; SODIUM COUPLED MONOCARBOXYLATE TRANSPORTER; SODIUM ION; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG PROTEIN BINDING; DRUG STRUCTURE; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; NONHUMAN; OOCYTE; PRIORITY JOURNAL; XENOPUS LAEVIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CATION TRANSPORT PROTEINS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FENOPROFEN; HUMANS; IBUPROFEN; MEMBRANE POTENTIALS; MOLECULAR STRUCTURE; NIACIN; OOCYTES; PROPIONATES; SODIUM; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; XENOPUS LAEVIS;

EID: 33745404319     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-0023-1     Document Type: Article

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