메뉴 건너뛰기




Volumn 8, Issue 2, 2013, Pages 139-148

The impact of obesity on male reproduction: Its biological significance

Author keywords

epididymal maturation; epididymis; hypothalamic pituitary testicular axis; leptin; male fertility; obesity; overweight; semen quality; spermatogenesis; spermatozoa

Indexed keywords

ALPHA GLUCOSIDASE; AROMATASE; CHORIONIC GONADOTROPIN; FOLLITROPIN; GONADORELIN; INHIBIN B; INTERLEUKIN 6; LUTEINIZING HORMONE; PLASMINOGEN ACTIVATOR INHIBITOR 1; REACTIVE OXYGEN METABOLITE; SEX HORMONE BINDING GLOBULIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84874630235     PISSN: 17446651     EISSN: 17448417     Source Type: Journal    
DOI: 10.1586/eem.13.8     Document Type: Review
Times cited : (8)

References (98)
  • 1
    • 0026657024 scopus 로고
    • Evidence for decreasing quality of semen during past 50 years
    • Carlsen E, Giwercman A, Keiding N, Skakkebaek NE. Evidence for decreasing quality of semen during past 50 years. BMJ 305 (6854), 609-613 (1992).
    • (1992) BMJ , vol.305 , Issue.6854 , pp. 609-613
    • Carlsen, E.1    Giwercman, A.2    Keiding, N.3    Skakkebaek, N.E.4
  • 2
    • 0034947140 scopus 로고    scopus 로고
    • Semen quality and male reproductive health: The controversy about human sperm concentration decline
    • Jouannet P, Wang C, Eustache F, Kold-Jensen T, Auger J. Semen quality and male reproductive health: the controversy about human sperm concentration decline. APMIS 109 (5), 333-344 (2001).
    • (2001) APMIS , vol.109 , Issue.5 , pp. 333-344
    • Jouannet, P.1    Wang, C.2    Eustache, F.3    Kold-Jensen, T.4    Auger, J.5
  • 3
    • 0033724655 scopus 로고    scopus 로고
    • The question of declining sperm density revisited: An analysis of 101 studies published 1934-1996
    • Swan SH, Elkin EP, Fenster L. The question of declining sperm density revisited: an analysis of 101 studies published 1934-1996. Environ. Health. Perspect. 108, 961-966 (2000).
    • (2000) Environ. Health. Perspect. , vol.108 , pp. 961-966
    • Swan, S.H.1    Elkin, E.P.2    Fenster, L.3
  • 5
    • 80051924339 scopus 로고    scopus 로고
    • Functional relationship between obesity and male reproduction: From humans to animal models
    • Teerds KJ, de Rooij DG, Keijer J. Functional relationship between obesity and male reproduction: from humans to animal models. Hum. Reprod. Update 17 (5), 667-683 (2011).
    • (2011) Hum. Reprod. Update , vol.17 , Issue.5 , pp. 667-683
    • Teerds, K.J.1    De Rooij, D.G.2    Keijer, J.3
  • 6
    • 5144232195 scopus 로고    scopus 로고
    • Body mass index in relation to semen quality and reproductive hormones among 1,558 Danish men
    • Jensen TK, Andersson AM, Jørgensen N et al. Body mass index in relation to semen quality and reproductive hormones among 1,558 Danish men. Fertil. Steril. 82 (4), 863-870 (2004).
    • (2004) Fertil. Steril. , vol.82 , Issue.4 , pp. 863-870
    • Jensen, T.K.1    Andersson, A.M.2    Jørgensen, N.3
  • 8
    • 52949105798 scopus 로고    scopus 로고
    • Impact of male obesity on infertility: A critical review of the current literature
    • Hammoud AO, Gibson M, Peterson CM, Meikle AW, Carrell DT. Impact of male obesity on infertility: a critical review of the current literature. Fertil. Steril. 90 (4), 897-904 (2008).
    • (2008) Fertil. Steril. , vol.90 , Issue.4 , pp. 897-904
    • Hammoud, A.O.1    Gibson, M.2    Peterson, C.M.3    Meikle, A.W.4    Carrell, D.T.5
  • 9
    • 72449208482 scopus 로고    scopus 로고
    • Obesity and testicular function
    • Mah PM, Wittert GA. Obesity and testicular function. Mol. Cell. Endocrinol. 316 (2), 180-186 (2010).
    • (2010) Mol. Cell. Endocrinol. , vol.316 , Issue.2 , pp. 180-186
    • Mah, P.M.1    Wittert, G.A.2
  • 10
    • 84155172577 scopus 로고    scopus 로고
    • Food intake and social habits in male patients and its relationship to intracytoplasmic sperm injection outcomes
    • Braga DP, Halpern G, Figueira Rde C, Setti AS, Iaconelli A Jr, Borges E Jr. Food intake and social habits in male patients and its relationship to intracytoplasmic sperm injection outcomes. Fertil. Steril. 97 (1), 53-59 (2012).
    • (2012) Fertil. Steril. , vol.97 , Issue.1 , pp. 53-59
    • Braga, D.P.1    Halpern, G.2    Figueira Rde, C.3    Setti, A.S.4    Iaconelli Jr., A.5    Borges Jr., E.6
  • 12
    • 26444515048 scopus 로고    scopus 로고
    • The decline of androgen levels in elderly men and its clinical and therapeutic implications
    • Kaufman JM, Vermeulen A. The decline of androgen levels in elderly men and its clinical and therapeutic implications. Endocr. Rev. 26 (6), 833-876 (2005).
    • (2005) Endocr. Rev. , vol.26 , Issue.6 , pp. 833-876
    • Kaufman, J.M.1    Vermeulen, A.2
  • 15
    • 0022910337 scopus 로고
    • Serum bioavailability of sex steroid hormones
    • Pardridge WM. Serum bioavailability of sex steroid hormones. Clin. Endocrinol. Metab. 15 (2), 259-278 (1986).
    • (1986) Clin. Endocrinol. Metab. , vol.15 , Issue.2 , pp. 259-278
    • Pardridge, W.M.1
  • 16
    • 0033678650 scopus 로고    scopus 로고
    • Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men
    • van den Beld AW, de Jong FH, Grobbee DE, Pols HA, Lamberts SW. Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men. J. Clin. Endocrinol. Metab. 85 (9), 3276-3282 (2000).
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , Issue.9 , pp. 3276-3282
    • Van Den Beld, A.W.1    De Jong, F.H.2    Grobbee, D.E.3    Pols, H.A.4    Lamberts, S.W.5
  • 18
    • 0025146990 scopus 로고
    • Changing relationships between testis size, Sertoli cell number and spermatogenesis in Sprague-Dawley rats
    • Berndtson WE, Thompson TL. Changing relationships between testis size, Sertoli cell number and spermatogenesis in Sprague-Dawley rats. J. Androl. 11 (5), 429-435 (1990).
    • (1990) J. Androl. , vol.11 , Issue.5 , pp. 429-435
    • Berndtson, W.E.1    Thompson, T.L.2
  • 19
    • 33746561251 scopus 로고    scopus 로고
    • Inhibin B is a better marker of spermatogenesis than other hormones in the evaluation of male factor infertility
    • Kumanov P, Nandipati K, Tomova A, Agarwal A. Inhibin B is a better marker of spermatogenesis than other hormones in the evaluation of male factor infertility. Fertil. Steril. 86 (2), 332-338 (2006).
    • (2006) Fertil. Steril. , vol.86 , Issue.2 , pp. 332-338
    • Kumanov, P.1    Nandipati, K.2    Tomova, A.3    Agarwal, A.4
  • 21
    • 0033942502 scopus 로고    scopus 로고
    • Sex hormones, obesity, fat distribution, Type 2 diabetes and insulin resistance: Epidemiological and clinical correlation
    • Haffner SM. Sex hormones, obesity, fat distribution, Type 2 diabetes and insulin resistance: epidemiological and clinical correlation. Int. J. Obes. Relat. Metab. Disord. 24 (Suppl. 2), S56-S58 (2000).
    • (2000) Int. J. Obes. Relat. Metab. Disord. , vol.24 , Issue.SUPPL. 2
    • Haffner, S.M.1
  • 22
    • 0026070702 scopus 로고
    • Effect of obesity and body fat distribution on sex hormones and insulin in men
    • Pasquali R, Casimirri F, Cantobelli S et al. Effect of obesity and body fat distribution on sex hormones and insulin in men. Metab. Clin. Exp. 40 (1), 101-104 (1991).
    • (1991) Metab. Clin. Exp. , vol.40 , Issue.1 , pp. 101-104
    • Pasquali, R.1    Casimirri, F.2    Cantobelli, S.3
  • 23
    • 0033304558 scopus 로고    scopus 로고
    • Leptin and androgens in male obesity: Evidence for leptin contribution to reduced androgen levels
    • Isidori AM, Caprio M, Strollo F et al. Leptin and androgens in male obesity: evidence for leptin contribution to reduced androgen levels. J. Clin. Endocrinol. Metab. 84 (10), 3673-3680 (1999).
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , Issue.10 , pp. 3673-3680
    • Isidori, A.M.1    Caprio, M.2    Strollo, F.3
  • 24
    • 0033757537 scopus 로고    scopus 로고
    • Decreased androgen levels in massively obese men may be associated with impaired function of the gonadostat
    • Lima N, Cavaliere H, Knobel M, Halpern A, Medeiros-Neto G. Decreased androgen levels in massively obese men may be associated with impaired function of the gonadostat. Int. J. Obes. Relat. Metab. Disord. 24 (11), 1433-1437 (2000).
    • (2000) Int. J. Obes. Relat. Metab. Disord. , vol.24 , Issue.11 , pp. 1433-1437
    • Lima, N.1    Cavaliere, H.2    Knobel, M.3    Halpern, A.4    Medeiros-Neto, G.5
  • 25
    • 47549107694 scopus 로고    scopus 로고
    • Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: The European Male Aging Study
    • European Male Aging Study Group
    • Wu FC, Tajar A, Pye SR et al.; European Male Aging Study Group. Hypothalamic-pituitary-testicular axis disruptions in older men are differentially linked to age and modifiable risk factors: the European Male Aging Study. J. Clin. Endocrinol. Metab. 93 (7), 2737-2745 (2008).
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , Issue.7 , pp. 2737-2745
    • Wu, F.C.1    Tajar, A.2    Pye, S.R.3
  • 26
    • 0027210856 scopus 로고
    • Attenuated luteinizing hormone (LH) pulse amplitude but normal LH pulse frequency, and its relation to plasma androgens in hypogonadism of obese men
    • Vermeulen A, Kaufman JM, Deslypere JP, Thomas G. Attenuated luteinizing hormone (LH) pulse amplitude but normal LH pulse frequency, and its relation to plasma androgens in hypogonadism of obese men. J. Clin. Endocrinol. Metab. 76 (5), 1140-1146 (1993).
    • (1993) J. Clin. Endocrinol. Metab. , vol.76 , Issue.5 , pp. 1140-1146
    • Vermeulen, A.1    Kaufman, J.M.2    Deslypere, J.P.3    Thomas, G.4
  • 28
    • 0034890103 scopus 로고    scopus 로고
    • Physiological role of adipose tissue: White adipose tissue as an endocrine and secretory organ
    • Trayhurn P, Beattie JH. Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ. Proc. Nutr. Soc. 60 (3), 329-339 (2001).
    • (2001) Proc. Nutr. Soc. , vol.60 , Issue.3 , pp. 329-339
    • Trayhurn, P.1    Beattie, J.H.2
  • 29
    • 0034456463 scopus 로고    scopus 로고
    • Expression of the leptin receptor during germ cell development in the mouse testis
    • El-Hefnawy T, Ioffe S, Dym M. Expression of the leptin receptor during germ cell development in the mouse testis. Endocrinology 141 (7), 2624-2630 (2000).
    • (2000) Endocrinology , vol.141 , Issue.7 , pp. 2624-2630
    • El-Hefnawy, T.1    Ioffe, S.2    Dym, M.3
  • 30
    • 33846001719 scopus 로고    scopus 로고
    • Expression of leptin and leptin receptor in the testis of fertile and infertile patients
    • Ishikawa T, Fujioka H, Ishimura T, Takenaka A, Fujisawa M. Expression of leptin and leptin receptor in the testis of fertile and infertile patients. Andrologia 39 (1), 22-27 (2007).
    • (2007) Andrologia , vol.39 , Issue.1 , pp. 22-27
    • Ishikawa, T.1    Fujioka, H.2    Ishimura, T.3    Takenaka, A.4    Fujisawa, M.5
  • 31
    • 32144439859 scopus 로고    scopus 로고
    • Altered luteinizing hormone and testosterone secretion in middle-aged obese men with obstructive sleep apnea
    • Luboshitzky R, Lavie L, Shen-Orr Z, Herer P. Altered luteinizing hormone and testosterone secretion in middle-aged obese men with obstructive sleep apnea. Obes. Res. 13 (4), 780-786 (2005).
    • (2005) Obes. Res. , vol.13 , Issue.4 , pp. 780-786
    • Luboshitzky, R.1    Lavie, L.2    Shen-Orr, Z.3    Herer, P.4
  • 32
    • 0242383371 scopus 로고    scopus 로고
    • Endocrine effects of nasal continuous positive airway pressure in male patients with obstructive sleep apnoea
    • Meston N, Davies RJ, Mullins R, Jenkinson C, Wass JA, Stradling JR. Endocrine effects of nasal continuous positive airway pressure in male patients with obstructive sleep apnoea. J. Intern. Med. 254 (5), 447-454 (2003).
    • (2003) J. Intern. Med. , vol.254 , Issue.5 , pp. 447-454
    • Meston, N.1    Davies, R.J.2    Mullins, R.3    Jenkinson, C.4    Wass, J.A.5    Stradling, J.R.6
  • 34
    • 27344450660 scopus 로고    scopus 로고
    • Estrogen regulation of testicular function
    • Akingbemi BT. Estrogen regulation of testicular function. Reprod. Biol. Endocrinol. 3, 51 (2005).
    • (2005) Reprod. Biol. Endocrinol. , vol.3 , pp. 51
    • Akingbemi, B.T.1
  • 35
    • 17444362664 scopus 로고    scopus 로고
    • Letrozole normalizes serum testosterone in severely obese men with hypogonadotropic hypogonadism
    • de Boer H, Verschoor L, Ruinemans-Koerts J, Jansen M. Letrozole normalizes serum testosterone in severely obese men with hypogonadotropic hypogonadism. Diabetes. Obes. Metab. 7 (3), 211-215 (2005).
    • (2005) Diabetes. Obes. Metab. , vol.7 , Issue.3 , pp. 211-215
    • De Boer, H.1    Verschoor, L.2    Ruinemans-Koerts, J.3    Jansen, M.4
  • 37
    • 0035137587 scopus 로고    scopus 로고
    • Evidence of a treatable endocrinopathy in infertile men
    • Pavlovich CP, King P, Goldstein M, Schlegel PN. Evidence of a treatable endocrinopathy in infertile men. J. Urol. 165 (3), 837-841 (2001).
    • (2001) J. Urol. , vol.165 , Issue.3 , pp. 837-841
    • Pavlovich, C.P.1    King, P.2    Goldstein, M.3    Schlegel, P.N.4
  • 39
    • 77957205789 scopus 로고    scopus 로고
    • An aromatase polymorphism modulates the relationship between weight and estradiol levels in obese men
    • Hammoud A, Carrell DT, Meikle AW et al. An aromatase polymorphism modulates the relationship between weight and estradiol levels in obese men. Fertil. Steril. 94 (5), 1734-1738 (2010).
    • (2010) Fertil. Steril. , vol.94 , Issue.5 , pp. 1734-1738
    • Hammoud, A.1    Carrell, D.T.2    Meikle, A.W.3
  • 41
    • 0348134969 scopus 로고    scopus 로고
    • Leptin and leptin receptor in human seminal plasma and in human spermatozoa
    • Jope T, Lammert A, Kratzsch J, Paasch U, Glander HJ. Leptin and leptin receptor in human seminal plasma and in human spermatozoa. Int. J. Androl. 26 (6), 335-341 (2003).
    • (2003) Int. J. Androl. , vol.26 , Issue.6 , pp. 335-341
    • Jope, T.1    Lammert, A.2    Kratzsch, J.3    Paasch, U.4    Glander, H.J.5
  • 42
    • 77954562886 scopus 로고    scopus 로고
    • Is male fertility associated with type 2 diabetes mellitus? Int
    • Bener A, Al-Ansari AA, Zirie M, Al-Hamaq AO. Is male fertility associated with type 2 diabetes mellitus? Int. Urol. Nephrol. 41 (4), 777-784 (2009).
    • (2009) Urol. Nephrol. , vol.41 , Issue.4 , pp. 777-784
    • Bener, A.1    Al-Ansari, A.A.2    Zirie, M.3    Al-Hamaq, A.O.4
  • 43
    • 43449133625 scopus 로고    scopus 로고
    • The metabolic syndrome and male infertility
    • Kasturi SS, Tannir J, Brannigan RE. The metabolic syndrome and male infertility. J. Androl. 29 (3), 251-259 (2008).
    • (2008) J. Androl. , vol.29 , Issue.3 , pp. 251-259
    • Kasturi, S.S.1    Tannir, J.2    Brannigan, R.E.3
  • 45
    • 45249108491 scopus 로고    scopus 로고
    • Rosiglitazone increases bioactive testosterone and reduces waist circumference in hypogonadal men with Type 2 diabetes
    • Kapoor D, Channer KS, Jones TH. Rosiglitazone increases bioactive testosterone and reduces waist circumference in hypogonadal men with Type 2 diabetes. Diab. Vasc. Dis. Res. 5 (2), 135-137 (2008).
    • (2008) Diab. Vasc. Dis. Res. , vol.5 , Issue.2 , pp. 135-137
    • Kapoor, D.1    Channer, K.S.2    Jones, T.H.3
  • 46
    • 26444609724 scopus 로고    scopus 로고
    • Inhibin B in men with severe obesity and after weight reduction following gastroplasty
    • Globerman H, Shen-Orr Z, Karnieli E, Aloni Y, Charuzi I. Inhibin B in men with severe obesity and after weight reduction following gastroplasty. Endocr. Res. 31 (1), 17-26 (2005).
    • (2005) Endocr. Res. , vol.31 , Issue.1 , pp. 17-26
    • Globerman, H.1    Shen-Orr, Z.2    Karnieli, E.3    Aloni, Y.4    Charuzi, I.5
  • 47
    • 33746394167 scopus 로고    scopus 로고
    • Inhibin-B levels in healthy young adult men and prepubertal boys: Is obesity the cause for the contemporary decline in sperm count because of fewer Sertoli cells? J
    • Winters SJ, Wang C, Abdelrahaman E, Hadeed V, Dyky MA, Brufsky A. Inhibin-B levels in healthy young adult men and prepubertal boys: is obesity the cause for the contemporary decline in sperm count because of fewer Sertoli cells? J. Androl. 27 (4), 560-564 (2006).
    • (2006) Androl. , vol.27 , Issue.4 , pp. 560-564
    • Winters, S.J.1    Wang, C.2    Abdelrahaman, E.3    Hadeed, V.4    Dyky, M.A.5    Brufsky, A.6
  • 48
    • 34548633710 scopus 로고    scopus 로고
    • Leptin levels in infertile male patients are correlated with inhibin B, testosterone and SHBG but not with sperm characteristics
    • Zorn B, Osredkar J, Meden-Vrtovec H, Majdic G. Leptin levels in infertile male patients are correlated with inhibin B, testosterone and SHBG but not with sperm characteristics. Int. J. Androl. 30, 439-444 (2007).
    • (2007) Int. J. Androl. , vol.30 , pp. 439-444
    • Zorn, B.1    Osredkar, J.2    Meden-Vrtovec, H.3    Majdic, G.4
  • 49
    • 17144466340 scopus 로고    scopus 로고
    • The Danish National Birth Cohort - Its background, structure and aim
    • Olsen J, Melbye M, Olsen SF et al. The Danish National Birth Cohort - its background, structure and aim. Scand. J. Public Health 29 (4), 300-307 (2001).
    • (2001) Scand. J. Public Health , vol.29 , Issue.4 , pp. 300-307
    • Olsen, J.1    Melbye, M.2    Olsen, S.F.3
  • 53
    • 69149095345 scopus 로고    scopus 로고
    • Associations between andrological measures, hormones and semen quality in fertile Australian men: Inverse relationship between obesity and sperm output
    • Stewart TM, Liu DY, Garrett C, Jørgensen N, Brown EH, Baker HW. Associations between andrological measures, hormones and semen quality in fertile Australian men: inverse relationship between obesity and sperm output. Hum. Reprod. 24 (7), 1561-1568 (2009).
    • (2009) Hum. Reprod. , vol.24 , Issue.7 , pp. 1561-1568
    • Stewart, T.M.1    Liu, D.Y.2    Garrett, C.3    Jørgensen, N.4    Brown, E.H.5    Baker, H.W.6
  • 54
    • 84858391597 scopus 로고    scopus 로고
    • Obesity and increased risk for oligozoospermia and azoospermia
    • Obesity-Fertility Collaborative Group
    • Sermondade N, Faure C, Fezeu L, Lévy R, Czernichow S; Obesity-Fertility Collaborative Group. Obesity and increased risk for oligozoospermia and azoospermia. Arch. Intern. Med. 172 (5), 440-442 (2012).
    • (2012) Arch. Intern. Med. , vol.172 , Issue.5 , pp. 440-442
    • Sermondade, N.1    Faure, C.2    Fezeu, L.3    Lévy, R.4    Czernichow, S.5
  • 55
    • 77954409583 scopus 로고    scopus 로고
    • Overweight and seminal quality: A study of 794 patients
    • Martini AC, Tissera A, Estofán D et al. Overweight and seminal quality: a study of 794 patients. Fertil. Steril. 94 (5), 1739-1743 (2010).
    • (2010) Fertil. Steril. , vol.94 , Issue.5 , pp. 1739-1743
    • Martini, A.C.1    Tissera, A.2    Estofán, D.3
  • 56
    • 77954484607 scopus 로고    scopus 로고
    • The impact of body mass index on semen parameters and reproductive hormones in human males: A systematic review with meta-analysis
    • MacDonald AA, Herbinson GP, Showell M, Farquhar CM. The impact of body mass index on semen parameters and reproductive hormones in human males: a systematic review with meta-analysis. Hum. Reprod. Update 16, 293-311 (2010).
    • (2010) Hum. Reprod. Update , vol.16 , pp. 293-311
    • Macdonald, A.A.1    Herbinson, G.P.2    Showell, M.3    Farquhar, C.M.4
  • 57
    • 36049042227 scopus 로고    scopus 로고
    • Do reproductive hormones explain the association between body mass index and semen quality? Asian J
    • Qin DD, Yuan W, Zhou WJ, Cui YQ, Wu JQ, Gao ES. Do reproductive hormones explain the association between body mass index and semen quality? Asian J. Androl. 9 (6), 827-834 (2007).
    • (2007) Androl. , vol.9 , Issue.6 , pp. 827-834
    • Qin, D.D.1    Yuan, W.2    Zhou, W.J.3    Cui, Y.Q.4    Wu, J.Q.5    Gao, E.S.6
  • 58
    • 3242755921 scopus 로고    scopus 로고
    • Androgenregulated genes in the murine epididymis
    • Chauvin TR, Griswold MD. Androgenregulated genes in the murine epididymis. Biol. Reprod. 71 (2), 560-569 (2004).
    • (2004) Biol. Reprod. , vol.71 , Issue.2 , pp. 560-569
    • Chauvin, T.R.1    Griswold, M.D.2
  • 60
    • 0031941824 scopus 로고    scopus 로고
    • Seminal plasma α-glucosidase activity and male infertility
    • Mahmoud AM, Geslevich J, Kint J et al. Seminal plasma α-glucosidase activity and male infertility. Hum. Reprod. 13 (3), 591-595 (1998).
    • (1998) Hum. Reprod. , vol.13 , Issue.3 , pp. 591-595
    • Mahmoud, A.M.1    Geslevich, J.2    Kint, J.3
  • 61
    • 0033057144 scopus 로고    scopus 로고
    • Androgen regulation of glycosidase secretion in epithelial cell cultures from human epididymis
    • Castellón EA, Huidobro CC. Androgen regulation of glycosidase secretion in epithelial cell cultures from human epididymis. Hum. Reprod. 14 (6), 1522-1527 (1999).
    • (1999) Hum. Reprod. , vol.14 , Issue.6 , pp. 1522-1527
    • Castellón, E.A.1    Huidobro, C.C.2
  • 62
    • 34248373254 scopus 로고    scopus 로고
    • Neutral α-glucosidase activity in mouse: A marker of epididymal function? Reprod
    • Martini AC, Molina RI, Vincenti LM et al. Neutral α-glucosidase activity in mouse: a marker of epididymal function? Reprod. Fertil. Dev. 19 (4), 563-568 (2007).
    • (2007) Fertil. Dev. , vol.19 , Issue.4 , pp. 563-568
    • Martini, A.C.1    Molina, R.I.2    Vincenti, L.M.3
  • 63
    • 33646339136 scopus 로고    scopus 로고
    • Impact of body mass index values on sperm quantity and quality
    • Kort HI, Massey JB, Elsner CW et al. Impact of body mass index values on sperm quantity and quality. J. Androl. 27 (3), 450-452 (2006).
    • (2006) J. Androl. , vol.27 , Issue.3 , pp. 450-452
    • Kort, H.I.1    Massey, J.B.2    Elsner, C.W.3
  • 65
    • 0036172658 scopus 로고    scopus 로고
    • Absence of microdeletions in the y chromosome in patients with Prader-Willi syndrome with cryptorchidism
    • Suzuki Y, Sasagawa I, Tateno T, Yazawa H, Ashida J, Nakada T. Absence of microdeletions in the Y chromosome in patients with Prader-Willi syndrome with cryptorchidism. Int. J. Androl. 25 (1), 1-5 (2002).
    • (2002) Int. J. Androl. , vol.25 , Issue.1 , pp. 1-5
    • Suzuki, Y.1    Sasagawa, I.2    Tateno, T.3    Yazawa, H.4    Ashida, J.5    Nakada, T.6
  • 66
    • 0041700224 scopus 로고    scopus 로고
    • Sexual function in men older than 50 years of age: Results from the health professionals follow-up study
    • Bacon CG, Mittleman MA, Kawachi I, Giovannucci E, Glasser DB, Rimm EB. Sexual function in men older than 50 years of age: results from the health professionals follow-up study. Ann. Intern. Med. 139 (3), 161-168 (2003).
    • (2003) Ann. Intern. Med. , vol.139 , Issue.3 , pp. 161-168
    • Bacon, C.G.1    Mittleman, M.A.2    Kawachi, I.3    Giovannucci, E.4    Glasser, D.B.5    Rimm, E.B.6
  • 67
    • 0034040591 scopus 로고    scopus 로고
    • Erectile dysfunction and coronary risk factors: Prospective results from the Massachusetts male aging study
    • Feldman HA, Johannes CB, Derby CA et al. Erectile dysfunction and coronary risk factors: prospective results from the Massachusetts male aging study. Prev. Med. 30 (4), 328-338 (2000).
    • (2000) Prev. Med. , vol.30 , Issue.4 , pp. 328-338
    • Feldman, H.A.1    Johannes, C.B.2    Derby, C.A.3
  • 68
    • 79957491763 scopus 로고    scopus 로고
    • Testosterone deficiency and risk factors in the metabolic syndrome: Implications for erectile dysfunction
    • Guay AT, Traish A. Testosterone deficiency and risk factors in the metabolic syndrome: implications for erectile dysfunction. Urol. Clin. North Am. 38 (2), 175-183 (2011).
    • (2011) Urol. Clin. North Am. , vol.38 , Issue.2 , pp. 175-183
    • Guay, A.T.1    Traish, A.2
  • 69
    • 78651247085 scopus 로고    scopus 로고
    • Cardiovascular diseases and erectile dysfunction: The two faces of the coin of androgen deficiency
    • Yassin AA, Akhras F, El-Sakka AI, Saad F. Cardiovascular diseases and erectile dysfunction: the two faces of the coin of androgen deficiency. Andrologia 43 (1), 1-8 (2011).
    • (2011) Andrologia , vol.43 , Issue.1 , pp. 1-8
    • Yassin, A.A.1    Akhras, F.2    El-Sakka, A.I.3    Saad, F.4
  • 71
    • 0019960045 scopus 로고
    • Mild Hypogonadotropic hypogonadism in obese men
    • Strain GW, Zumoff B, Kream J et al. Mild Hypogonadotropic hypogonadism in obese men. Metab. Clin. Exp. 31 (9), 871-875 (1982).
    • (1982) Metab. Clin. Exp. , vol.31 , Issue.9 , pp. 871-875
    • Strain, G.W.1    Zumoff, B.2    Kream, J.3
  • 72
    • 70349510639 scopus 로고    scopus 로고
    • Mechanisms of obesity and related pathologies: Androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction
    • Traish AM, Feeley RJ, Guay A. Mechanisms of obesity and related pathologies: androgen deficiency and endothelial dysfunction may be the link between obesity and erectile dysfunction. FEBS J. 276 (20), 5755-5767 (2009).
    • (2009) FEBS J. , vol.276 , Issue.20 , pp. 5755-5767
    • Traish, A.M.1    Feeley, R.J.2    Guay, A.3
  • 73
    • 0033566591 scopus 로고    scopus 로고
    • Nitric oxide and penile erection: Is erectile dysfunction another manifestation of vascular disease? Cardiovasc
    • Sullivan ME, Thompson CS, Dashwood MR et al. Nitric oxide and penile erection: is erectile dysfunction another manifestation of vascular disease? Cardiovasc. Res. 43 (3), 658-665 (1999).
    • (1999) Res. , vol.43 , Issue.3 , pp. 658-665
    • Sullivan, M.E.1    Thompson, C.S.2    Dashwood, M.R.3
  • 74
    • 62649124818 scopus 로고    scopus 로고
    • Diabetes, obesity, and erectile dysfunction
    • Tamler R. Diabetes, obesity, and erectile dysfunction. Gend. Med. 6 (Suppl. 1), 4-16 (2009).
    • (2009) Gend. Med. , vol.6 , Issue.SUPPL. 1 , pp. 4-16
    • Tamler, R.1
  • 75
    • 33646371004 scopus 로고    scopus 로고
    • Role of oxidative stress in the pathophysiological mechanism of erectile dysfunction
    • Agarwal A, Nandipati KC, Sharma RK, Zippe CD, Raina R. Role of oxidative stress in the pathophysiological mechanism of erectile dysfunction. J. Androl. 27 (3), 335-347 (2006).
    • (2006) J. Androl. , vol.27 , Issue.3 , pp. 335-347
    • Agarwal, A.1    Nandipati, K.C.2    Sharma, R.K.3    Zippe, C.D.4    Raina, R.5
  • 76
    • 0034883169 scopus 로고    scopus 로고
    • Contribution of environmental factors to the risk of male infertility
    • Oliva A, Spira A, Multigner L. Contribution of environmental factors to the risk of male infertility. Hum. Reprod. 16 (8), 1768-1776 (2001).
    • (2001) Hum. Reprod. , vol.16 , Issue.8 , pp. 1768-1776
    • Oliva, A.1    Spira, A.2    Multigner, L.3
  • 77
    • 37749022163 scopus 로고    scopus 로고
    • Endocrine disruptors and estrogenic effects on male reproductive axis
    • Sikka SC, Wang R. Endocrine disruptors and estrogenic effects on male reproductive axis. Asian J. Androl. 10 (1), 134-145 (2008).
    • (2008) Asian J. Androl. , vol.10 , Issue.1 , pp. 134-145
    • Sikka, S.C.1    Wang, R.2
  • 78
    • 56749143082 scopus 로고    scopus 로고
    • TNF-α and IL-6 affect human sperm function by elevating nitric oxide production
    • Lampiao F, du Plessis SS. TNF-α and IL-6 affect human sperm function by elevating nitric oxide production. Reprod. Biomed. Online 17 (5), 628-631 (2008).
    • (2008) Reprod. Biomed. Online , vol.17 , Issue.5 , pp. 628-631
    • Lampiao, F.1    Du Plessis, S.S.2
  • 79
    • 15444366991 scopus 로고    scopus 로고
    • Metabolic syndrome: A comprehensive perspective based on interactions between obesity, diabetes, and inflammation
    • Dandona P, Aljada A, Chaudhuri A, Mohanty P, Garg R. Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation. Circulation 111 (11), 1448-1454 (2005).
    • (2005) Circulation , vol.111 , Issue.11 , pp. 1448-1454
    • Dandona, P.1    Aljada, A.2    Chaudhuri, A.3    Mohanty, P.4    Garg, R.5
  • 80
    • 26244441533 scopus 로고    scopus 로고
    • Oxidant stress, inflammation and atherogenesis
    • Davì G, Falco A. Oxidant stress, inflammation and atherogenesis. Lupus 14 (9), 760-764 (2005).
    • (2005) Lupus , vol.14 , Issue.9 , pp. 760-764
    • Davì, G.1    Falco, A.2
  • 82
    • 84870715031 scopus 로고    scopus 로고
    • Reactive oxygen species and sperm function - In sickness and in health
    • Aitken RJ, Jones KT, Robertson SA. Reactive oxygen species and sperm function - in sickness and in health. J. Androl. 33 (6), 1096-1106 (2012).
    • (2012) J. Androl. , vol.33 , Issue.6 , pp. 1096-1106
    • Aitken, R.J.1    Jones, K.T.2    Robertson, S.A.3
  • 83
    • 77952779297 scopus 로고    scopus 로고
    • Environmental/lifestyle effects on spermatogenesis
    • Sharpe RM. Environmental/lifestyle effects on spermatogenesis. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 365 (1546), 1697-1712 (2010).
    • (2010) Philos. Trans. R. Soc. Lond., B, Biol. Sci. , vol.365 , Issue.1546 , pp. 1697-1712
    • Sharpe, R.M.1
  • 85
    • 0032408041 scopus 로고    scopus 로고
    • The parkes lecture. Heat and the testis
    • Setchell BP. The Parkes Lecture. Heat and the testis. J. Reprod. Fertil. 114 (2), 179-194 (1998).
    • (1998) J. Reprod. Fertil. , vol.114 , Issue.2 , pp. 179-194
    • Setchell, B.P.1
  • 86
    • 65949097241 scopus 로고    scopus 로고
    • A single, mild, transient scrotal heat stress causes hypoxia and oxidative stress in mouse testes, which induces germ cell death
    • Paul C, Teng S, Saunders PT. A single, mild, transient scrotal heat stress causes hypoxia and oxidative stress in mouse testes, which induces germ cell death. Biol. Reprod. 80 (5), 913-919 (2009).
    • (2009) Biol. Reprod. , vol.80 , Issue.5 , pp. 913-919
    • Paul, C.1    Teng, S.2    Saunders, P.T.3
  • 88
    • 0019349277 scopus 로고
    • Lipectomy in the treatment of scrotal lipomatosis
    • Shafik A, Olfat S. Lipectomy in the treatment of scrotal lipomatosis. Br. J. Urol. 53 (1), 55-61 (1981).
    • (1981) Br. J. Urol. , vol.53 , Issue.1 , pp. 55-61
    • Shafik, A.1    Olfat, S.2
  • 90
    • 2342432570 scopus 로고    scopus 로고
    • Sex hormones and sexual function in obese men losing weight
    • Kaukua J, Pekkarinen T, Sane T, Mustajoki P. Sex hormones and sexual function in obese men losing weight. Obes. Res. 11 (6), 689-694 (2003).
    • (2003) Obes. Res. , vol.11 , Issue.6 , pp. 689-694
    • Kaukua, J.1    Pekkarinen, T.2    Sane, T.3    Mustajoki, P.4
  • 92
    • 18744396408 scopus 로고    scopus 로고
    • Secondary male factor infertility after Roux-en-Y gastric bypass for morbid obesity: Case report
    • di Frega AS, Dale B, Di Matteo L, Wilding M. Secondary male factor infertility after Roux-en-Y gastric bypass for morbid obesity: case report. Hum. Reprod. 20 (4), 997-998 (2005).
    • (2005) Hum. Reprod. , vol.20 , Issue.4 , pp. 997-998
    • Di Frega, A.S.1    Dale, B.2    Di Matteo, L.3    Wilding, M.4
  • 93
    • 84856671356 scopus 로고    scopus 로고
    • Sperm parameters and male fertility after bariatric surgery: Three case series
    • Sermondade N, Massin N, Boitrelle F et al. Sperm parameters and male fertility after bariatric surgery: three case series. Reprod. Biomed. Online 24 (2), 206-210 (2012).
    • (2012) Reprod. Biomed. Online , vol.24 , Issue.2 , pp. 206-210
    • Sermondade, N.1    Massin, N.2    Boitrelle, F.3
  • 94
    • 33646110761 scopus 로고    scopus 로고
    • Obesity and androgens: Facts and perspectives
    • Pasquali R. Obesity and androgens: facts and perspectives. Fertil. Steril. 85 (5), 1319-1340 (2006).
    • (2006) Fertil. Steril. , vol.85 , Issue.5 , pp. 1319-1340
    • Pasquali, R.1
  • 95
    • 0036144667 scopus 로고    scopus 로고
    • Aromatase inhibitors for male infertility
    • Raman JD, Schlegel PN. Aromatase inhibitors for male infertility. J. Urol. 167 (2 Pt 1), 624-629 (2002).
    • (2002) J. Urol. , vol.167 , Issue.2 PART 1 , pp. 624-629
    • Raman, J.D.1    Schlegel, P.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.