Expression of the leptin receptor during germ cell development in the mouse testis

Endocrinology

Volumn 141, Issue 7, 2000, Pages 2624-2630

  El Hefnawy, Talal ^a,b   Ioffe, Sergey ^a   Dym, Martin ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; LEPTIN; LEPTIN RECEPTOR; TRANSCRIPTION FACTOR;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; GERM CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INFERTILITY; MALE; MOUSE; NONHUMAN; OBESITY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEMINIFEROUS TUBULE; SIGNAL TRANSDUCTION; SPERMATOGENESIS; SPERMATOGONIUM; TESTIS; WESTERN BLOTTING;

EID: 0034456463     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.141.7.7542     Document Type: Article

References (50)

1. The male reproductive system
2. Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
3. The OB protein (leptin) pathway-a link between adipose tissue mass and central neural networks
4. Weight-reducing effects of the plasma protein encoded by the obese gene
5. Effects of the obese gene product on body weight regulation in ob/ob mice
6. Leptin treatment rescues the sterility of genetically obese ob/ob males
7. Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
8. Evidence for GnRH regulation by leptin: Leptin administration prevents reduced pulsatile LH secretion during fasting
9. Leptin is a metabolic signal to the reproductive system
10. Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility
11. Is FSH required for maintenance of spermatogenesis in adult rats
12. Expression of leptin receptor isoforms in rat brain microvessels
13. Expression of leptin receptor mRNA and the long form splice variant in human anterior pituitary and pituitary adenoma
14. Abnormal splicing of the leptin receptor in diabetic mice
15. Leptin receptor signal transduction: OBRa and OBRb of fa type
16. Detection and quantification of the leptin receptor splice variants Ob-Ra, b, and, e in different mouse tissues
17. A short form of leptin receptor performs signal transduction
18. Molecular cloning of rat leptin receptor isoform complementary DNAs-identification of a missense mutation in Zucker fatty (fa/fa) rats
19. A role for leptin and its cognate receptor in hematopoiesis
20. Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells
21. The ful-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors
22. Defective STAT signaling by the leptin receptor in diabetic mice
23. Tyrosine phosphorylation of STAT3 by leptin through leptin receptor in mouse metaphase 2 stage oocyte
24. STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells
25. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3
26. Essential role of STAT3 for embryonic stem cell pluripotency
27. Leptin's actions on the reproductive axis: Perspectives and mechanisms
28. Serum leptin levels in males with delayed puberty during short-term pulsatile GnRH administration
29. Serum immunoreactive leptin concentrations in women with polycystic ovary syndrome
30. Choice of stimulation in polycystic ovarian syndrome: The influence of obesity
31. The expression of leptin and its receptors in pre-ovulatory human follicles
32. Expression of functional leptin receptors in the human ovary
33. Leptin antagonizes the insulin-like growth factor-I augmentation of steroidogenesis in granulosa and theca cells of the human ovary
34. Leptin directly stimulates aromatase activity in human luteinized granulosa cells
35. Direct intraovarian effects of leptin: Impairment of the synergistic action of insulin-like growth factor-I on follicle-stimulating hormone-dependent estradiol-17β production by rat ovarian granulosa cells
36. Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat
37. Expression of functional leptin receptors in rodent Leydig cells
38. Leptin inhibits testosterone secretion from adult rat testis in vitro
39. Passage of leptin across the blood-testis barrier
40. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
41. Leptin and human reproduction
42. Early onset of reproductive function in normal female mice treated with leptin
43. Hyperleptinaemia is associated with impaired gonadotrophin response to GnRH during late puberty in obese girls, not boys
44. Stage-specific expression of the FSH receptor gene in the prepubertal and adult rat seminiferous epithelium
45. Stage-specific regulation of stem cell factor gene expression in the rat seminiferous epithelium
46. Stage- and cell-specific gene expression and hormone regulation of the seminiferous epithelium
47. Stage-specific expression of nucleoprotein mRNAs during rat and mouse spermiogenesis
48. Germ cell-Sertoli cell interactions: Regulation by germ cells of the stage-specific expression of CP-2/cathepsin L mRNA by Sertoli cells
49. Expression of β-nerve growth factor and its receptor in rat seminiferous epithelium: Specific function at the onset of meiosis
50. bFGF and LIF signaling activates STAT3 in proliferating myoblasts