TNF-α and IL-6 affect human sperm function by elevating nitric oxide production

Reproductive BioMedicine Online

Volumn 17, Issue 5, 2008, Pages 628-631

  Lampiao, Fanuel ^a   du Plessis, Stefan S ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MALE; SEMEN ABNORMALITY; SPERMATOZOON MOTILITY;

EID: 56749143082     PISSN: 14726483     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1472-6483(10)60309-4     Document Type: Article

References (21)

1. Aksoy H, Aksoy Y, Ozbey I et al. 2000 The relationship between varicocele and semen nitric oxide concentrations. Urological Research 28, 357-359.
2. Alexander RB, Ponniah S, Hasday J, Hebel JR 1998 Elevated levels of proinflammatory cytokines in the semen of patients with chronic prostatitis/chronic pelvic pain syndrome. Urology 52, 744-749.
3. Comhaire F, Bosmans E, Ombelet W et al. 1994 Cytokines in semen of normal men and of patients with andrological diseases. American Journal of Reproductive Immunology 31, 99-103.
4. Diemer T, Hales DB, Weidner W 2003 Immune-endocrine interactions and Leydig cell function: the role of cytokines. Andrologia 35, 55-63.
5. Dimmeler S, Lottspeich F, Brüne B 1992 Nitric oxide causes ADP-ribosylation and inhibition of glyceraldehydes-3-phosphate dehydrogenase. Journal of Biological Chemistry 267, 16771-16774.
6. Eisermann J, Register KB, Strickler RC, Collins JL 1989 The effect of tumor necrosis factor on human sperm motility in vitro. Journal of Andrology 10, 270-274.
7. Hales DB, Diemer T, Hales KH 1999 Role of cytokines in testicular function. Endocrine 10, 201-217.
8. Huleihel M, Lunenfeld E, Levy A et al. 1996 Distinct expression levels of cytokines and soluble cytokine receptors in seminal plasma of fertile and infertile men. Fertility and Sterility 66, 135-139.
9. Hussenet F, Dousset B, Cordonnier JL et al. 1993 Tumor necrosis factor-α and interleukin 2 in normal and infected human fluid. Human Reproduction 8, 409-411.
10. Lampiao F, Strijdom H, Du Plessis SS 2006 Direct nitric oxide measurement in human spermatozoa: flow cytometric analysis using the fluorescent probe, diaminofluorescein. International Journal of Andrology 29, 564-567.
11. Matalliotakis I, Kiriakou D, Fragouli I et al. 1998 Interleukin-6 in seminal plasma of fertile and infertile men. Archives of Andrology 41, 43-50.
12. Nallella KP, Allamaneni SSR, Pasqualotto FF et al. 2004 Relationship of interleukin-6 with semen characteristics and oxidative stress in patients with varicocele. Urology 64, 1010-1013.
13. Naz RK, Kaplan P 1994 Increased levels of Interleukin-6 in seminal plasma of fertile and infertile men. Archives of Andrology 15, 220-227.
14. Ozmen B, Caglar GS, Koster F et al. 2007 Relationship between sperm DNA damage, induced acrosome reaction and viability in ICSI patients. Reproductive BioMedicine Online 15, 208-214.
15. Perdichizzi A, Nicoletti F, Vignera S et al. 2007 Effects of tumor necrosis factor-α on human sperm motility and apoptosis. Journal of Clinical Immunology 27, 152-162.
16. Sahin Z, Celik-Ozenci C, Akkoyunlu G et al. 2006 Increased expression of interleukin-1α and interleukin-1β is associated with experimental varicocele. Fertility and Sterility 85, 1265-1275.
17. Sakamoto Y, Ishikawa T, Kondo Y et al. 2008 The assessment of oxidative stress in infertile patients with varicocele. British Journal of Urology International 101, 1547-1552.
18. Syed V, Stephan JP, Gerard N et al. 1995 Residual bodies activate Sertoli cell interleukin-1α (IL-1α) release, which triggers IL-6 production by an autocrine mechanism, through the lipoxygenase pathway. Endocrinology 136, 3070-3078.
19. Tarrozi N, Bizzaro D, Flamigni C, Borini A 2007 Clinical relevance of sperm DNA damage in assisted reproduction. Reproductive BioMedicine Online 14, 746-757.
20. Weinberg TB, Doty E, Bonaventure J, Haney AF 1995 Nitric oxide inhibition of human sperm motility. Fertility and Sterility 64, 408-413.
21. World Health Organization 1999 WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. Cambridge University Press, Cambridge.