A chemical-biological study reveals C9-type iridoids as novel heat shock protein 90 (Hsp90) inhibitors

Journal of Medicinal Chemistry

Volumn 56, Issue 4, 2013, Pages 1583-1595

  Piaz, Fabrizio Dal ^a   Vassallo, Antonio ^b   Temraz, Abeer ^c   Cotugno, Roberta ^a   Belisario, Maria A ^a   Bifulco, Giuseppe ^a   Chini, Maria G ^a   Pisano, Claudio ^d   De Tommasi, Nunziatina ^a   Braca, Alessandra ^e  

^a UNIVERSITY OF SALERNO   (Italy)

^b UNIVERSITY OF BASILICATA   (Italy)

^c Al Azhar University   (Egypt)

^d Sigma Tau SpA   (Italy)

^e UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CITRATE SYNTHASE; HEAT SHOCK PROTEIN 90 INHIBITOR; IRIDOID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; COLLISIONALLY ACTIVATED DISSOCIATION; COMPLEX FORMATION; DIMERIZATION; ELECTROSPRAY MASS SPECTROMETRY; HETERONUCLEAR MULTIPLE BOND CORRELATION; HYDROGEN BOND; HYDROLYSIS; IN VITRO STUDY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR WEIGHT; NONHUMAN; PETIOLE; PLANT LEAF; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; SURFACE PLASMON RESONANCE; TABEBUIA; TABEBUIA ARGENTEA;

EID: 84874603530     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301398y     Document Type: Article

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